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Foligraf 150IU Injection is used to treat female infertility. It contains Urofollitropin which works by increasing oestrogen production that stimulates the development of the egg and mature follicles. In some cases, this medicine may cause side effects such as headache, stomach pain, nausea, vomiting, pelvic pain, and hot flushes. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Bharat Serums and Vaccines Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Foligraf 150IU Injection

Foligraf 150IU Injection is a specialised injection used in fertility medicine to stimulate the ovaries to produce and mature healthy eggs. It is typically prescribed to treat infertility in women who do not ovulate regularly, or as part of assisted reproductive technologies such as In Vitro Fertilisation (IVF) to help prepare multiple eggs for collection.

This medication is injected daily, and maintaining a strict schedule is essential for the best possible results. You should inject your dose at the same time each day to keep hormone levels stable. While food intake does not affect this injectable medicine, making supportive lifestyle adjustments—such as eating a balanced diet and avoiding smoking and alcohol—can optimise your overall treatment outcomes.

Most patients tolerate the treatment well, though some may experience mild side effects like headaches or minor discomfort at the injection site. However, it is vital to contact your healthcare provider immediately if you experience severe abdominal pain, swelling, or nausea, as these can be signs of a serious response in your ovaries.

Do not take this if you are already pregnant, have primary ovarian failure, or have untreated thyroid, pituitary, or adrenal gland issues. Foligraf 150IU Injection is also not suitable for individuals with ovarian cysts not caused by polycystic ovary syndrome (PCOS), or those experiencing unexplained vaginal bleeding.

Talk to your doctor or pharmacist about all other medications you are taking, as some fertility drugs may interact. It is also important to consult your healthcare provider if you are breastfeeding, as this treatment is not intended for nursing mothers or elderly individuals.

Uses of Foligraf 150IU Injection

Foligraf 150IU Injection is used in the treatment of female infertility. The detailed uses of Foligraf 150IU Injection are as follows:

  • Female Infertility: Foligraf 150IU Injection helps by stimulating the ovaries to develop and mature eggs in women who are unable to ovulate on their own.
  • Assisted Reproductive Technology (ART): This medication helps by encouraging the growth of multiple follicles simultaneously, which is required for procedures like In Vitro Fertilisation (IVF).

Key Benefits

Taking Foligraf 150IU Injection can help stimulate healthy follicle development and improve the chances of successful ovulation in women with certain fertility problems. Here are the key benefits of this treatment:

  • Stimulates follicle growth: Helps the ovaries develop and mature healthy follicles, increasing the likelihood of ovulation.
  • Supports ovulation: Encourages the release of mature eggs in women who do not ovulate regularly or have ovulation disorders.
  • Improves fertility treatment outcomes: Helps produce multiple mature eggs during assisted reproductive techniques such as IVF or ICSI, increasing the chances of successful egg retrieval.
  • Allows precise treatment planning: Enables your fertility specialist to closely monitor and control ovarian stimulation, helping optimize the timing of ovulation and fertility procedures.
  • Increases the chance of pregnancy: By promoting healthy egg development and ovulation, it improves the likelihood of achieving pregnancy when used as part of a medically supervised fertility treatment plan.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Foligraf 150IU Injection may be administered by your doctor, or you may be told to inject the medication yourself at home. Your doctor will train you on how to use Foligraf 150IU Injection at home. Check the label for directions and use it as advised by the doctor. Foligraf 150IU Injection should be administered subcutaneously (under the skin) on your lower abdomen, 1-2 inches below the navel, alternating between left and right and right sides.
  • Rotate injection site each time to prevent skin problems.
  • If there is any bleeding at your injection site, place a gauze pad over your injection site. Apply gentle pressure to stop the bleeding. Do not rub the site. If your injection site becomes sore or red, you may put ice on your injection site for a few minutes.

How Foligraf 150IU Injection Works

Foligraf 150IU Injection contains urofollitropin which works by mimicking the natural follicle-stimulating hormone (FSH) produced by your pituitary gland. When injected, it acts directly on your ovaries, binding to specific receptors to prompt the small sacs (follicles) that contain your eggs to grow and mature. Because it acts directly on the target tissue, it bypasses the brain's hormone-production center. This provides a direct, controlled stimulus to your ovaries, helping eggs reach the optimal size and maturity required for successful fertilization or collection.
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Alcohol

Caution

Interaction of Foligraf 150IU Injection with alcohol is unknown. Please consult a doctor before consuming alcohol while using Foligraf 150IU Injection .

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Pregnancy

Unsafe

Foligraf 150IU Injection is a category X pregnancy drug and is not recommended for use during pregnancy as it may cause multiple pregnancy (twins, triplets, etc.) and increase the risk of miscarriage, tubal pregnancy, birth defects or premature labour. However, please consult a doctor if you are pregnant.

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Breast Feeding

Unsafe

Foligraf 150IU Injection is contraindicated in breastfeeding women. It is unknown whether Foligraf 150IU Injection is excreted in human milk. Therefore, please consult a doctor if you are breastfeeding.

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Driving

Safe if prescribed

Foligraf 150IU Injection usually does not affect your ability to drive or operate machinery.

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Liver

Caution

If you have any concerns regarding the use of Foligraf 150IU Injection in patients with Liver problems, please consult a doctor.

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Kidney

Caution

If you have any concerns regarding the use of Foligraf 150IU Injection in patients with kidney problems, please consult a doctor.

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Children

Unsafe

Foligraf 150IU Injection is not recommended for children.

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before using Foligraf 150IU Injection . Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Limited information available for use of Foligraf 150IU Injection in elderly patients. Please consult your doctor.

What if I have taken an overdose of Foligraf 150IU Injection

If you suspect you have injected more than your prescribed dose, seek immediate medical attention or contact your fertility specialist right away. An overdose can lead to overstimulation of the ovaries, which requires prompt medical evaluation.

Diet & Lifestyle Advise

  • Modify physical activity: Avoid high-impact exercises, heavy lifting, or vigorous twisting motions during treatment, as enlarged ovaries are at risk of twisting (ovarian torsion).
  • Stay well-hydrated: Drink plenty of water and electrolyte-rich fluids daily, especially if you experience mild bloating or abdominal discomfort.
  • Avoid smoking and alcohol: Refrain from using tobacco products and drinking alcohol, as both can negatively impact egg quality and reduce the success rates of fertility treatments.
  • Maintain balanced nutrition: Focus on a nutrient-rich diet with adequate protein, leafy greens, and healthy fats to support your body's cellular environment during follicle development.
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How Soon It Starts Working

The time required for Foligraf 150IU Injection to start to work: The time required for Foligraf 150IU Injection to show its action is unknown. The time for which the effects of Foligraf 150IU Injection last: The duration of action for Foligraf 150IU Injection is clinically unknown.

What if you forget to take Foligraf 150IU Injection

If you miss an injection, contact your doctor or fertility clinic immediately for instructions. Do not inject a double dose to make up for the missed one, as this can increase your risk of severe complications.

Storage

•Store Foligraf 150IU Injection according to the specific manufacturer guidelines provided with your pack. •Most formulations should be stored either in the refrigerator between 2°C to 8°C (36°F to 46°F) or at controlled room temperature up to 25°C (77°F).
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Keep Refrigerated. Do not freeze.

Drug Warnings

  • Inspect the solution before use: Always check the vial before drawing up Foligraf 150IU Injection . Do not use it if the solution appears discolored or contains visible particles.
  • Rotate injection sites regularly: Change your injection site each day by alternating between the abdomen and thighs to help reduce skin irritation and prevent hard lumps from forming.
  • Do not reuse or share injection equipment: Never reuse syringes or needles, and never share your medication or injection devices with anyone else, as this may increase the risk of infection.
  • Seek immediate medical attention for serious symptoms: Contact your doctor immediately if you develop sudden severe abdominal pain, chest pain, leg swelling, or other unusual symptoms during treatment.
  • Attend regular monitoring appointments: Keep all scheduled ultrasound scans and blood tests so your doctor can monitor your response to treatment and adjust your therapy as needed.

Drug-Drug Interactions

verifiedApollotooltip
  • Other gonadotropins or fertility medicines: Taking these medicines alongside Foligraf 150IU Injection may overstimulate the ovaries and increase the risk of ovarian hyperstimulation syndrome (OHSS).
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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  • No clinically significant food interactions are known with Foligraf 150IU Injection when used as directed. 
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[HORMONES]

FAQs

Foligraf 150IU Injection is used to treat infertility in women whose ovaries do not produce eggs and in women receiving treatments like IVF (in-vitro fertilization).
Foligraf 150IU Injection contains Urofollitropin that works similar to follicle stimulating hormone (natural sex hormone). Foligraf 150IU Injection increases oestrogen production that stimulates the development of egg and mature follicle in women having ovulation (release of egg from ovary) problems and those undergoing IVF treatments.
You are not recommended to take Foligraf 150IU Injection with ganirelix (used to prevent premature ovulation) as co-administration of these two medicines may reduce the effects of Foligraf 150IU Injection . However, please consult a doctor before taking Foligraf 150IU Injection with other medicines.
Foligraf 150IU Injection alone does not cause ovulation (release of egg from ovaries). Foligraf 150IU Injection in combination with other medicine such as human chorionic gonadotrophin (hCG) may stimulate ovulation.
Foligraf 150IU Injection may be used in women undergoing IVF (in-vitro fertilization) treatment to help ovaries develop multiple follicles (egg sacs) where eggs develop. However, please consult a doctor before using Foligraf 150IU Injection .
Foligraf 150IU Injection may increase the risk of uterine cancer. However, if you experience any unusual vaginal bleeding, please consult a doctor immediately.
Foligraf 150IU Injection may cause miscarriage, ectopic pregnancy (pregnancy outside the womb), birth defects or multiple pregnancy (twins, triplets). Therefore, avoid Foligraf 150IU Injection if you are pregnant and consult a doctor.
If you miss a dose of Foligraf 150IU Injection , inform your doctor or healthcare provider as soon as possible. They will advise you on the next steps and when to administer the next dose.
The common side effects of Foligraf 150IU Injection may include headache, stomach pain, nausea, vomiting, pelvic pain, hot flushes (sudden feeling of warmth), or inflammation of the throat and nasal passage. Most of these side effects of Foligraf 150IU Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Foligraf 150IU Injection is injected either under the skin (subcutaneously) or into the muscle (intramuscularly) using sterile, single-use syringes. Your healthcare provider will show you how to prepare and administer the injection. Talk to your doctor or pharmacist if you are unsure of the technique.
Yes, many patients inject this medication at home after receiving proper training from their clinic. Do not attempt to self-inject until you feel fully confident and have been cleared by your healthcare provider. Talk to your doctor if you have any doubts.
Severe stomach pain, bloating, or nausea can be a sign of a serious condition called Ovarian Hyperstimulation Syndrome (OHSS). Stop using Foligraf 150IU Injection and seek emergency medical care or contact your clinic immediately. Talk to your doctor right away if this occurs.
Yes, because this medication stimulates the development of multiple egg follicles, it increases the likelihood of becoming pregnant with twins, triplets, or more. Your clinical team will monitor you closely via ultrasound to manage this risk. Talk to your doctor about your specific risk level.
The medication is typically taken daily for 7 to 14 days per cycle, depending on how your follicles grow. Your doctor will monitor your progress with frequent blood tests and ultrasounds to decide when the eggs are ready. Talk to your doctor to understand your timeline.
Storage depends on the specific brand and formulation your pharmacist dispenses. Some require refrigeration, while others can be kept at room temperature up to a certain limit. Always check the package label or talk to your pharmacist to verify correct storage.
No, this medication must not be used during pregnancy. If you suspect you have become pregnant during your treatment cycle, stop using Foligraf 150IU Injection immediately and contact your clinic. Talk to your doctor to confirm your pregnancy status.
OHSS is a recognized medical risk where the ovaries become swollen and painful from producing too many eggs. It is more common in women with PCOS or those receiving high doses, which is why close ultrasound monitoring is mandatory. Talk to your doctor about how this risk is managed for you.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

34 NAND BHAVANBABU GENU ROAD NEW HANUMAN LANE MUMBAI MH 000000 IN
Other Info - FOL0132
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