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Forecox-150 Tablet is used to treat tuberculosis. It works by preventing the growth of bacteria or killing bacteria. In some cases, you may experience certain common side effects such as weakness, nausea, vomiting, malaise (feeling of discomfort), fatigue and vision problems. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

ETHAMBUTOL-275MG+ISONIAZID-100MG+PYRAZINAMIDE-500MG+RIFAMPICIN-150MG

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Forecox-150 Tablet

The medicine Forecox-150 Tablet is a prescription oral tablet used to treat active tuberculosis, a serious bacterial infection that primarily affects the lungs. Its main medical purpose is to eliminate the tuberculosis bacteria from your body, preventing the disease from spreading or worsening. By targeting the bacteria at multiple stages of growth, it helps you recover safely and completely.

To get the best results, you must take Forecox-150 Tablet daily and consistently at the same time every day to keep a steady level of medicine in your body. It is best to take this medicine on an empty stomach, either one hour before or two hours after meals. Additionally, avoiding alcohol completely and eating nutrient-rich foods will significantly support your recovery.

While taking Forecox-150 Tablet, you may notice some common, harmless side effects, such as your urine, saliva, or tears turning a temporary red-orange colour. However, you must contact your doctor immediately if you experience serious side effects like yellowing of your skin or eyes, severe stomach pain, or changes in your vision.

Before starting this treatment, tell your doctor if you have a history of liver disease, kidney problems, gout, or eye conditions. Do not take this if you have severe liver damage or are known to be allergic to any of the active components in this medicine.

This medicine can interact with alcohol, raising the risk of severe liver damage, and it can make certain medications, like hormonal birth control, much less effective. If you are pregnant, breastfeeding, or an older adult, you must talk to your doctor or pharmacist to ensure this treatment is safe for your specific situation.

Uses of Forecox-150 Tablet

Forecox-150 Tablet is used to treat tuberculosis. The detailed uses of Forecox-150 Tablet are as follows:

  • Active Tuberculosis (TB): Forecox-150 Tablet is prescribed to treat active tuberculosis infections in the lungs and other parts of the body. It works by stopping the growth, multiplication, and spread of the bacteria causing the infection.

Key Benefits

Forecox-150 Tablet helps treat tuberculosis effectively by combining multiple anti-tuberculosis medicines into a single formulation. This comprehensive approach targets the bacteria in different stages of growth, helping control the infection and supporting successful recovery.

  • Simplifies Tuberculosis Treatment: By combining four essential tuberculosis medicines into one tablet, Forecox-150 Tablet reduces the number of pills you need to take each day. This simplified treatment approach can help improve adherence to therapy and support better treatment outcomes.
  • Helps Relieve Tuberculosis Symptoms: As the bacterial infection comes under control, symptoms such as persistent cough, fever, night sweats, fatigue, and weight loss gradually improve, helping you regain strength and return to your daily activities.
  • Helps Prevent Drug Resistance: Using multiple anti-tuberculosis medicines together helps reduce the risk of the bacteria developing resistance to treatment. This supports the effectiveness of therapy throughout the full treatment course and helps prevent the spread of resistant strains.
Side effects of Forecox-150 Tablet
  • If you have excess nerve pain and numbness, soak in Epsom salt and warm water. This can help ease the pain and associated discomfort.
  • Use compression socks and make sure to rest for a while to get relief from pain.
  • Avoid smoking and intake of alcohol or fluids that aggravate the pain.
  • Massage your feet or affected area often to get relief from pain. Take the medication prescribed by your doctor without fail.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Directions for Use

To get the full benefit of this medication and ensure it works properly, follow these step-by-step instructions:

  • Take Forecox-150 Tablet on an empty stomach, either 1 hour before or 2 hours after a meal, as food can significantly reduce how much of the medicine your body absorbs.
  • Swallow the tablet whole with a full glass of water. Do not crush, chew, break, or dissolve the tablet.
    Take your dose at the exact same time every day to keep a constant amount of the medicine in your bloodstream.
  • Continue taking this medicine for the entire duration prescribed by your doctor, even if your symptoms clear up and you start feeling better. Stopping early can cause the infection to return and make the bacteria resistant to treatment.
  • Always follow your doctor's exact instructions regarding your treatment plan. If you have questions about how to take this medication, talk to your doctor or pharmacist.

How Forecox-150 Tablet Works

The medicine Forecox-150 Tablet combines four active ingredients, rifampicin, isoniazid, pyrazinamide and ethambutol, that work in harmony to attack and destroy tuberculosis bacteria from multiple angles. Rifampicin stops the bacteria from reproducing by blocking its genetic copying machinery, specifically preventing it from making essential proteins. Isoniazid targets the outer defences of the bacteria by blocking the production of mycolic acids, which are critical building blocks for the bacterial cell wall. Without a strong wall, the bacteria die. Pyrazinamide specifically targets bacteria living in highly acidic environments inside your body's immune cells. It disrupts their energy production, weakening them so they cannot survive. Ethambutol works by interfering with the synthesis of another key structural component of the bacterial cell wall, stopping the bacteria from multiplying and growing. By attacking the bacteria's genetic material, cell wall structure, and energy production simultaneously, Forecox-150 Tablet ensures that even dormant or hard-to-reach bacteria are successfully eliminated.
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Alcohol

Unsafe

Avoid alcohol consumption while taking Forecox-150 Tablet as it could lead to increased dizziness and liver damage.

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Pregnancy

Caution

Please consult your doctor if you are pregnant, your doctor will prescribe Forecox-150 Tablet only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Forecox-150 Tablet passes into breast milk. Do not breastfeed while taking Forecox-150 Tablet. Consult your doctor for further advice.

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Driving

Unsafe

Forecox-150 Tablet may cause dizziness, vision problems, numbness and tingling sensation in hands and feet. Do not drive or operate machinery if you experience these symptoms.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor before taking Forecox-150 Tablet if you have liver impairment/liver disease.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease.

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Children

Unsafe

Forecox-150 Tablet is not recommended for use in children.

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Heart

Caution

Forecox-150 Tablet can be used in heart patients if prescribed by the physician. Please consult your physician if you have any concerns.

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Geriatrics

Consult your doctor

Forecox-150 Tablet should be given to elderly patients only if recommended by a doctor. Please consult your doctor before using Forecox-150 Tablet.

What if I have taken an overdose of Forecox-150 Tablet

Do not take more than the prescribed dose of Forecox-150 Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Avoid alcohol entirely: Alcohol significantly increases the risk of severe liver damage when combined with Forecox-150 Tablet.
  • Take vitamin B6: Ask your doctor if you should take a pyridoxine (vitamin B6) supplement. This is often recommended to prevent nerve tingling or numbness in your hands and feet while on this medication.
  • Limit high-tyramine and high-histamine foods: Avoid eating aged cheeses, red wine, cured meats, yeast extracts, and certain fish like tuna or mackerel. Combining these foods with your medicine can trigger a reaction causing headaches, sweating, a fast heartbeat, or flushing.
  • Eat a nutrient-dense diet: Focus on high-protein foods, fresh vegetables, and whole grains to help your body rebuild tissue, boost your immune system, and recover from the infection.
  • Stay hydrated: Drink plenty of water throughout the day to help your kidneys safely filter and clear the medication from your system.
health query

Have a query?

How Soon It Starts Working

The time required for Forecox-150 Tablet to start to work: The time required for Forecox-150 Tablet to show its action is unknown. The time for which the effects of Forecox-150 Tablet last: The duration of action for Forecox-150 Tablet is unknown.

What if you forget to take Forecox-150 Tablet

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next dose at the scheduled time. Do not take a double dose.

Storage

• Store Forecox-150 Tablet at room temperature, strictly between 15°C and 30°C (59°F to 86°F). • Keep the tablets in their original blister packaging or container to protect them from light and moisture.

Drug Warnings

  • Do not wear soft contact lenses while taking this medicine, as it can permanently stain them a red-orange colour. Switch to glasses during your treatment.
  • If you use hormonal birth control (such as pills, patches, or rings), use a reliable non-hormonal barrier method like condoms, because Forecox-150 Tablet makes hormonal contraceptives much less effective.
  • Attend all scheduled doctor appointments for regular blood tests to check your liver function and for regular eye exams to monitor your vision.
  • Do not take antacids containing aluminium or magnesium within 2 hours of taking your medication, as they can stop your body from absorbing Forecox-150 Tablet properly.
  • Always inform any healthcare provider, including your dentist, surgeon, or laboratory technician, that you are taking Forecox-150 Tablet, as it can interfere with certain medical test results.

Drug-Drug Interactions

verifiedApollotooltip

Before using Forecox-150 Tablet, it is important to understand how it may interact with other medicines, foods, or existing health conditions.

Drug-Drug Interactions

  • Oral blood thinners (e.g., warfarin): Forecox-150 Tablet may reduce the effectiveness of certain anticoagulants, potentially affecting blood clotting control. Your doctor may recommend closer monitoring and dose adjustments if these medicines are used together.
  • Heart medicines (e.g., digoxin, beta-blockers): This medicine may alter the blood levels or effectiveness of certain cardiovascular medications. Regular monitoring may be required to ensure optimal treatment response.
  • Anti-seizure medicines: Some anticonvulsants may have reduced effectiveness when taken with Forecox-150 Tablet, which could affect seizure control. Inform your doctor if you are receiving treatment for epilepsy or other seizure disorders.
  • Antifungal medicines: Forecox-150 Tablet may lower the blood levels of certain antifungal medications, potentially reducing their effectiveness in treating fungal infections.
  • Oral diabetes medicines: This medicine may affect the levels or effectiveness of some medicines used to control blood sugar, requiring closer monitoring of glucose levels during treatment.
  • Pain relievers: Certain analgesics may become less effective when taken with Forecox-150 Tablet. Consult your healthcare provider before starting any new pain medication.
  • Other medicines that may affect the liver (e.g., high-dose paracetamol/acetaminophen): Using these medicines together may increase the risk of liver-related side effects or liver damage. Your doctor may recommend additional monitoring if combination therapy is necessary.

Drug-Food Interactions

  • Foods high in tyramine (e.g., aged cheeses, soy sauce): Consuming large amounts of tyramine-rich foods while taking Forecox-150 Tablet may increase the risk of flushing, headaches, rapid heartbeats, or changes in blood pressure.
  • Foods high in histamine (e.g., tuna, mackerel, yeast-containing products): These foods may increase the likelihood of symptoms such as flushing, headache, palpitations, or discomfort in susceptible individuals.

Drug-Disease Interaction

  • Liver disease: Patients with pre-existing liver impairment may be at increased risk of adverse effects and may require closer monitoring during treatment.
  • Kidney disease: Reduced kidney function may affect how your body processes and eliminates Forecox-150 Tablet, potentially increasing the risk of side effects. Dose adjustments or additional monitoring may be necessary.
  • Gout: This medicine may increase uric acid levels in the blood, which can trigger gout attacks or worsen existing gout symptoms.
  • Diabetes: Forecox-150 Tablet may affect blood glucose control. Patients with diabetes should monitor their blood sugar levels regularly and consult their doctor if they notice significant changes in glucose readings.
Ethambutol + Isoniazid + Pyrazinamide + RifampicinVoriconazole
Critical
Ethambutol + Isoniazid + Pyrazinamide + RifampicinDarunavir
Critical

Drug-Drug Interactions

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Ethambutol + Isoniazid + Pyrazinamide + RifampicinVoriconazole
Critical
How does the drug interact with Forecox-150 Tablet:
Co-administration of Voriconazole with Ethambutol, Isoniazid, Pyrazinamide and Rifampicin can decrease the blood levels of Voriconazole.

How to manage the interaction:
Although there is an interaction between Voriconazole and Ethambutol, Isoniazid, Pyrazinamide and Rifampicin, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Ethambutol + Isoniazid + Pyrazinamide + RifampicinDarunavir
Critical
How does the drug interact with Forecox-150 Tablet:
Co-administration of darunavir with Forecox-150 Tablet can decrease the blood levels of darunavir.

How to manage the interaction:
Although there is an interaction between darunavir and Forecox-150 Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Ethambutol + Isoniazid + Pyrazinamide + RifampicinIndinavir
Critical
How does the drug interact with Forecox-150 Tablet:
Co-administration of Indinavir with Forecox-150 Tablet can decrease the blood levels of Indinavir.

How to manage the interaction:
Although there is an interaction between Indinavir and Forecox-150 Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Ethambutol + Isoniazid + Pyrazinamide + RifampicinPirfenidone
Critical
How does the drug interact with Forecox-150 Tablet:
Taking pirfenidone with Forecox-150 Tablet can increase the side effects.

How to manage the interaction:
Although there is an interaction between pirfenidone and Forecox-150 Tablet, they can be taken if prescribed by a doctor. However, if you experience any unusual symptoms like dizziness, rashes, loose stools, nausea, vomiting, dark colour urine or light colour stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Ethambutol + Isoniazid + Pyrazinamide + RifampicinRanolazine
Critical
How does the drug interact with Forecox-150 Tablet:
Co-administration of Ranolazine with Forecox-150 Tablet can decrease the blood levels of Ranolazine.

How to manage the interaction:
Although there is an interaction between Ranolazine and Forecox-150 Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Ethambutol + Isoniazid + Pyrazinamide + RifampicinSaquinavir
Critical
How does the drug interact with Forecox-150 Tablet:
Taking Saquinavir with Forecox-150 Tablet can increase the side effects.

How to manage the interaction:
Although there is an interaction between Saquinavir and Forecox-150 Tablet, they can be taken if prescribed by a doctor. However, if you experience any unusual symptoms like loss of hunger, yellowing of eyes or skin, nausea, vomiting, dark colour urine or light colour stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Ethambutol + Isoniazid + Pyrazinamide + RifampicinNelfinavir
Severe
How does the drug interact with Forecox-150 Tablet:
Co-administration of Nelfinavir with Ethambutol, Isoniazid, Pyrazinamide and Rifampicin can decrease the blood levels of Nelfinavir.

How to manage the interaction:
Although there is an interaction between Nelfinavir and Ethambutol, Isoniazid, Pyrazinamide and Rifampicin, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Ethambutol + Isoniazid + Pyrazinamide + RifampicinSimvastatin
Severe
How does the drug interact with Forecox-150 Tablet:
Co-administration of Simvastatin with Ethambutol, Isoniazid, Pyrazinamide and Rifampicin can decrease the blood levels of Simvastatin.

How to manage the interaction:
Although there is an interaction between Simvastatin and Ethambutol, Isoniazid, Pyrazinamide and Rifampicin, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Ethambutol + Isoniazid + Pyrazinamide + RifampicinVigabatrin
Severe
How does the drug interact with Forecox-150 Tablet:
Taking Vigabatrin with Ethambutol, Isoniazid, Pyrazinamide and Rifampicin can increase the risk of vision loss.

How to manage the interaction:
Although there is an interaction between Vigabatrin and with Ethambutol, Isoniazid, Pyrazinamide and Rifampicin, they can be taken if prescribed by a doctor. However, if you experience any unusual symptoms or eye sight problems, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Ethambutol + Isoniazid + Pyrazinamide + RifampicinBCG vaccine
Severe
How does the drug interact with Forecox-150 Tablet:
Co-administration of BCG vaccine with Ethambutol, Isoniazid, Pyrazinamide and Rifampicin can decrease the blood levels of BCG vaccine.

How to manage the interaction:
Although there is an interaction between BCG vaccine and Ethambutol, Isoniazid, Pyrazinamide and Rifampicin, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTI- TUBERCULOSIS]

FAQs

Forecox-150 Tablet belongs to the group of medicines called anti-tuberculosis drugs primarily used to treat tuberculosis. Tuberculosis is an infectious disease that mainly affects the lungs but can also spread to other body parts such as kidneys, brain, spine and bone marrow.
Forecox-150 Tablet is a combination of four anti-tuberculosis drugs, namely: Rifampicin, isoniazid, pyrazinamide, and ethambutol. Forecox-150 Tablet works by killing the bacteria named Mycobacterium tuberculosis which causes TB (tuberculosis).
Do not stop taking Forecox-150 Tablet despite symptomatic relief. To treat your condition effectually, continue taking Forecox-150 Tablet for as long as it has been prescribed for you.
Do not take Forecox-150 Tablet along with antacids as it might decrease the effectiveness of Forecox-150 Tablet. Maintain a minimum gap of 1 hour between both. However, please consult your doctor before taking other medicines with Forecox-150 Tablet.
Consult your doctor before taking Forecox-150 Tablet with other medicines. Your doctor would suggest the right time, dose and precautions before taking Forecox-150 Tablet with other drugs.
Forecox-150 Tablet contains isoniazid which might interact with foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine and beer. Avoid these foods while taking Forecox-150 Tablet.
Forecox-150 Tablet might decrease the effectiveness of oral contraceptives (birth control pills). This could lead to an unplanned pregnancy. Instead, use a reliable barrier method of contraception such as condoms or the coil while taking Forecox-150 Tablet. Consult your doctor if you have any concerns regarding this, your doctor may suggest an alternate method of contraception.
Forecox-150 Tablet may cause discolouration of teeth, sweat, urine, sputum (phlegm), saliva or tears. The colour in tears may last for some time even after you stop taking Forecox-150 Tablet. Do not worry as it is a common side-effect of Forecox-150 Tablet.
Yes, Forecox-150 Tablet might permanently stain soft contact lenses. Use spectacles and avoid wearing contact lens while taking Forecox-150 Tablet.
Forecox-150 Tablet may affect test results of some blood tests such as tests for folate, vitamin B12 and liver function. Inform the person doing the tests that you are taking Forecox-150 Tablet.
Yes, Forecox-150 Tablet may cause liver problems, especially in people who are 35 and older. Consult your doctor if you notice symptoms such as yellowing of eyes or skin, dark urine, pale stools, weakness, loss of appetite, nausea or vomiting. Your doctor may advise you to get regular liver tests while taking Forecox-150 Tablet to check how your liver is functioning.
Take Forecox-150 Tablet as directed by your doctor. Take Forecox-150 Tablet on an empty stomach, either one hour before eating or two hours after a meal. Swallow it as whole with a glass of water; do not crush, chew, or break it.
You are recommended to avoid alcohol while taking Forecox-150 Tablet, as it may cause headache, sweating, dizziness, and feeling lightheaded or faint. Please, consult the doctor if you have any concerns.
Yes, Forecox-150 Tablet may cause visual impairment (blurred vision, loss of vision). This condition may affect the patient's ability to drive or operate machinery safely. However, if you notice any changes in your vision, stop taking Forecox-150 Tablet and inform your doctor immediately.
Store Forecox-150 Tablet at a temperature below 30°C in a cool and dry place as advised on the label. Protect from light and moisture. Keep it out of reach of children. Forecox-150 Tablet should be disposed, by following local guidelines or asking your pharmacist how to properly dispose of any unused medicine.
Forecox-150 Tablet causes side effects such as weakness, nausea, vomiting, malaise (feeling of discomfort), and fatigue. However, please contact a doctor if these side effects persist longer.
This is a very common and harmless side effect of one of the active ingredients in the medicine. It causes a reddish-orange discolouration of body fluids, including urine, saliva, sweat, tears, and stool. This will go away once you complete your treatment. Talk to your doctor if you have concerns.
One of the components of this medicine can cause a temporary deficiency of vitamin B6, which can lead to nerve problems like tingling, burning, or numbness in your hands and feet. Taking a daily vitamin B6 (pyridoxine) supplement helps prevent this side effect. Talk to your doctor or pharmacist for a specific recommendation.

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Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - FOR0021
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