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compositionComposition:IFOSFAMIDE-1000MG
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Fosfa 1 gm With Mesna Injection is used to treat blood cancer, breast cancer, non-small cell lung cancer, ovarian cancer, testicular cancer, and pancreatic cancer. It contains Ifosfamide which works by preventing the growth and multiplication of cancer cells. In some cases, this medicine may cause side effects such as nausea, vomiting, low number of red/white blood cells, hair loss, and infection. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

IFOSFAMIDE-1000MG

Manufacturer/Marketer :

Getwell Oncology Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Fosfa 1 gm With Mesna Injection

Fosfa 1 gm With Mesna Injection is a specialised prescription medication injected into the body to treat specific types of cancer, particularly testicular cancer that has not responded well to other treatments. It belongs to a group of cancer-fighting medicines that target and slow down the growth of abnormal cells. Because of its strength and the way it must be given, this medicine is only administered under the direct supervision of an experienced medical team in a hospital or specialised clinic.

This medication is not a daily home drug; it is given in treatment cycles. Your medical team will schedule your treatment sessions with specific rest periods in between to allow your body to recover. Since it is delivered directly into a vein, it does not depend on food intake, but eating light meals before your scheduled treatment can help manage potential nausea. Staying highly hydrated by drinking plenty of water before, during, and after your session is one of the most important steps you must take to protect your bladder from irritation.

While Fosfa 1 gm With Mesna Injection is highly effective, it can cause side effects. Common temporary issues include hair loss, nausea, vomiting, and feeling very tired. However, you must contact your doctor immediately if you notice serious symptoms such as blood in your urine, painful urination, severe confusion, or signs of an infection like a sudden fever or chills.

Before you begin treatment, it is vital to tell your healthcare provider about your complete medical history. Do not take this if you have a severe bladder infection, active bladder inflammation or if your bone marrow is severely suppressed, meaning your body is not producing enough blood cells. Your doctor will carefully evaluate your kidneys, liver, and blood counts before starting each cycle.

Fosfa 1 gm With Mesna Injection can interact with other medicines, such as certain antibiotics, anti-seizure drugs, or other chemotherapy medicines, which may increase the risk of kidney or liver damage. You should avoid alcohol during your treatment because it can worsen nausea and place extra strain on your liver. If you are pregnant, planning to become pregnant, or breastfeeding, you must consult your doctor immediately, as this medicine can harm an unborn baby. Elderly individuals may also require closer monitoring, as they are often more sensitive to the side effects on the kidneys and brain.

Uses of Fosfa 1 gm With Mesna Injection

Your doctor may prescribe Fosfa 1 gm With Mesna Injection for several serious conditions, often as part of a combination chemotherapy plan:

  • Testicular cancer: Fosfa 1 gm With Mesna Injection helps by stopping the growth and spread of cancer cells in the testicles, particularly when initial treatments have not been successful.
  • Soft tissue sarcomas: This medicine is used to treat cancers that develop in supporting tissues of the body, such as muscles, fat, blood vessels, and nerves, by slowing down the division of abnormal cells.
  • Other solid tumours: In certain specialised cases, doctors use Fosfa 1 gm With Mesna Injection to treat bone cancers or lung cancers by interfering with the replication of cancer cells.
     

Key Benefits

Fosfa 1 gm With Mesna Injection helps treat certain advanced and difficult-to-treat cancers by slowing or stopping the growth of rapidly dividing cancer cells. By controlling tumour growth, it supports cancer treatment and helps improve quality of life.

  • Helps Control Cancer Growth: By targeting rapidly dividing cancer cells, Fosfa 1 gm With Mesna Injection helps shrink tumours, slows disease progression, and may improve the effectiveness of other cancer treatments, including surgery.
  • Helps Prevent the Spread of Cancer: By limiting the multiplication of cancer cells, Fosfa 1 gm With Mesna Injection helps reduce the risk of the cancer spreading to other parts of the body.
  • Relieves Cancer-Related Symptoms: By reducing tumour size and controlling disease progression, Fosfa 1 gm With Mesna Injection may help relieve symptoms such as pain, pressure, or discomfort caused by the tumour, improving daily comfort and overall well-being during treatment.
     

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Fosfa 1 gm With Mesna Injection will be administered by a nurse or doctor.
  • Do not self-administer

How Fosfa 1 gm With Mesna Injection Works

To understand how Fosfa 1 gm With Mesna Injection works, it helps to think of cancer cells as rapidly copying machines. This medicine works by attaching itself to the DNA inside these fast-growing cancer cells. Once attached, it damages the DNA strands so they cannot separate or replicate correctly. Because the cancer cells cannot repair this damage, they are prevented from dividing and growing, which eventually causes them to break down and die. Since cancer cells divide much faster than most healthy cells in your body, they are far more sensitive to this DNA damage.
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Alcohol

Caution

Consumption of alcohol is not recommended while receiving this Fosfa 1 gm With Mesna Injection as it may increase the risk of adverse effects such as dizziness, drowsiness, abnormal muscle movements, seizures.

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Pregnancy

Unsafe

Fosfa 1 gm With Mesna Injection is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before receiving this Fosfa 1 gm With Mesna Injection.

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Breast Feeding

Caution

Fosfa 1 gm With Mesna Injection is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine. Your doctor may advise you to discontinue breastfeeding for a specific period of time or prescribe an alternative medicine based on your clinical condition.

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Driving

Caution

Use of this Fosfa 1 gm With Mesna Injection may cause blurred vision or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this Fosfa 1 gm With Mesna Injection.

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Liver

Caution

Fosfa 1 gm With Mesna Injection should be used with caution in patients with liver disease. A dose adjustment of Fosfa 1 gm With Mesna Injection may be needed. Please consult your doctor.

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Kidney

Caution

Fosfa 1 gm With Mesna Injection should be used with caution in patients with kidney disease. A dose adjustment of Fosfa 1 gm With Mesna Injection may be needed. Please consult your doctor.

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Children

Caution

Fosfa 1 gm With Mesna Injection is not recommended for use in patients below 18 years of age unless prescribed by your physician. Your doctor may prescribe this medicine if the benefits significantly outweigh the risks. In such a case, the patient should be monitored closely for any adverse effects.

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before using Fosfa 1 gm With Mesna Injection. Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Limited information available for use of Fosfa 1 gm With Mesna Injection in elderly patients. Please consult your doctor.

What if I have taken an overdose of Fosfa 1 gm With Mesna Injection

Your medical team will carefully measure and administer every dose under strict protocols, making an overdose highly unlikely. In the rare event of an accidental overdose, clinical staff are trained to recognise the signs immediately and will provide supportive care to manage symptoms. If you experience severe sudden side effects shortly after a treatment session, notify your healthcare team immediately.

Diet & Lifestyle Advise

  • Drink plenty of fluids: Try to drink 2 to 3 liters of water daily, especially on treatment days, to flush your bladder and help prevent severe irritation.
  • Eat small, frequent meals: To manage nausea and keep your energy up, eat light, bland meals (such as crackers, toast, or rice) throughout the day instead of three large meals.
  • Avoid raw foods: Wash all fruits and vegetables thoroughly, and avoid raw fish, runny eggs, or undercooked meats to protect yourself from infections while your immune system is weak.
  • Practise gentle oral care: Use a soft-bristled toothbrush to clean your teeth and avoid alcohol-based mouthwashes to prevent bleeding gums and mouth sores.
     
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How Soon It Starts Working

The time required for Fosfa 1 gm With Mesna Injection to start to work: Fosfa 1 gm With Mesna Injection starts to show its action within 2 hours of administration. The time for which the effects of Fosfa 1 gm With Mesna Injection last: Fosfa 1 gm With Mesna Injection effect lasts for 24 hours.

What if you forget to take Fosfa 1 gm With Mesna Injection

Since this medication is given by professionals in a clinical setting, a missed dose is very rare. However, if you miss a scheduled treatment appointment, contact your cancer clinic immediately to reschedule your session and keep your therapy on track.

Storage

• The dry powder is kept at room temperature, between 20°C to 25°C (68°F to 77°F), away from direct light and excessive heat. • Once the healthcare team mixes the powder into a liquid, it must be used within a specific time or stored under strict ref
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Keep Refrigerated. Do not freeze.

Drug Warnings

  • Check your urine colour frequently during your treatment cycle; if it looks pink, red, or smoky, contact your doctor immediately.
  • Watch your injection site closely during the infusion and tell your nurse immediately if you feel any burning, stinging, or swelling where the needle is placed.
  • Avoid receiving live vaccines (such as the shingles or yellow fever vaccine) while using Fosfa 1 gm With Mesna Injection, as your weakened immune system cannot handle them safely.
  • Use highly effective birth control during treatment and for several months afterward, as Fosfa 1 gm With Mesna Injection can cause severe birth defects.
  • Keep a safe distance from anyone who is actively sick with a cold, flu, or other contagious infections.
     

Drug-Drug Interactions

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  • Other chemotherapy drugs: Combining these may increase the risk of bone marrow suppression, lowering your blood counts further.
  • Medicines that cause kidney damage: Taking certain antibiotics or antivirals alongside Fosfa 1 gm With Mesna Injection can significantly increase the strain on your kidneys.
  • Anti-seizure medications: Some of these drugs can speed up how your liver processes Fosfa 1 gm With Mesna Injection, which can either make the treatment less effective or increase its toxic side effects.
     
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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  • Grapefruit and grapefruit juice: Can interfere with the liver enzymes that break down Fosfa 1 gm With Mesna Injection, potentially raising the levels of the medicine in your blood and increasing side effects.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTINEOPLASTIC]

FAQs

Fosfa 1 gm With Mesna Injection is used to treat blood cancer, breast cancer, non-small cell lung cancer, ovarian cancer, testicular cancer and pancreatic cancer.
Fosfa 1 gm With Mesna Injection contains ‘ifosfamide’, which is an anti-cancer drug. Fosfa 1 gm With Mesna Injection works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.Â
Fosfa 1 gm With Mesna Injection causes common side effects like nausea, vomiting, anemia (low number of red blood cells), hair loss, decreased white blood cell count, infection, blood in urine, CNS toxicity. Most of these side effects of Fosfa 1 gm With Mesna Injection do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.
Yes, Fosfa 1 gm With Mesna Injection used in combination with other chemotherapy medicines, radiotherapy, and surgery to treat cancer of blood, breast, lung, ovaries, pancreas, testes, and lymph nodes.
Fosfa 1 gm With Mesna Injection may increase the risk of toxic effects on the heart and could lead to congestive heart failure. So Fosfa 1 gm With Mesna Injection should be taken as advised by your doctor.
Fosfa 1 gm With Mesna Injection is given as a slow injection or infusion directly into a vein (intravenously) by a trained medical professional in a hospital or clinic setting. Talk to your doctor for more details about your specific infusion schedule.
Drinking plenty of water helps flush the medicine out of your bladder quickly. This prevents the drug's breakdown products from sitting in your bladder and causing severe bleeding or irritation. Talk to your doctor about how much fluid you should drink.
Doctors usually inject a protective medicine called mesna alongside Fosfa 1 gm With Mesna Injection. Mesna safely binds to harmful substances in your bladder to shield the bladder lining from damage. Talk to your doctor or pharmacist if you want to know more about this protective treatment.
Yes, temporary hair loss is a very common side effect of Fosfa 1 gm With Mesna Injection. Hair typically begins to grow back a few months after your final chemotherapy session is completed. Talk to your doctor if you have concerns about managing hair loss.
You should avoid live vaccines during your treatment because your immune system is weakened by Fosfa 1 gm With Mesna Injection, making these vaccines unsafe. Always consult your healthcare team before getting any vaccine, including flu shots. Talk to your doctor or pharmacist to plan safe vaccinations.
Fosfa 1 gm With Mesna Injection can temporarily lower your white blood cells, red blood cells, and platelets. This increases your risk of catching infections, feeling extremely tired, and bruising or bleeding easily. Talk to your doctor about having your blood counts monitored regularly.
It is best to avoid alcohol during your treatment. Alcohol can stress your liver and kidneys, make nausea worse, and increase the risk of dehydration. Talk to your doctor or pharmacist for personalized guidance.
No, Fosfa 1 gm With Mesna Injection can cause severe harm to an unborn baby. Both men and women must use highly reliable birth control during treatment and for a specified time after the last dose. Talk to your doctor to discuss safe family planning and fertility options before starting treatment.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

464, Udyog Vihar, Phase-V Sector 19, Gurugram Haryana 122016
Other Info - FOS0076
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