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compositionComposition:FUROSEMIDE-20MG+SPIRONOLACTONE-50MG
prescription
Prescription Medicine
info
Frusidip Tablet

Frusidip Tablet is used to treat oedema (fluid retention). It works by increasing the amount of urine that is passed out from the kidneys. Sometimes, you may experience side effects like low blood pressure (hypotension), dehydration, electrolyte disturbances (potassium and sodium), headache, nausea, or dizziness. Inform your doctor if you are pregnant, breastfeeding, taking any other medicine or have pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

FUROSEMIDE-20MG+SPIRONOLACTONE-50MG

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Frusidip Tablet

Frusidip Tablet is an oral medicine prescribed to help remove excess fluid build-up in the body, a condition known as 'oedema'. It is commonly used for individuals dealing with fluid retention caused by heart, liver, or kidney issues, as well as to help manage high blood pressure. By helping your body get rid of extra water and salt, this medicine relieves strain on your heart and blood vessels.

To get the most benefit, you should take Frusidip Tablet consistently every day, exactly as your doctor has prescribed. It is usually best to take this medicine in the morning, with or without food, so that the increased need to urinate does not disturb your sleep. Making simple lifestyle adjustments, such as reducing your daily salt intake and staying moderately active, can significantly improve how well this medicine works for you.

While taking Frusidip Tablet, you may experience some mild and common side effects like mild dizziness, dry mouth, or needing to urinate more frequently. However, you must contact your doctor immediately if you notice serious symptoms such as severe muscle cramps, irregular heartbeats, or signs of extreme dehydration.

Talk to your doctor or pharmacist before starting this medicine if you have pre-existing health conditions like diabetes, gout, or severe kidney problems. Do not take this if you are completely unable to pass urine, have severe kidney failure, or have dangerously high potassium levels in your blood.

This medicine can interact with alcohol, which may worsen dizziness or cause your blood pressure to drop too low, so it is best to limit or avoid alcohol. You should also consult your doctor before using Frusidip Tablet if you are pregnant, planning to breastfeed, or are an older adult, as these groups may require special monitoring or dosage adjustments.

Uses of Frusidip Tablet

Frusidip Tablet is used to help remove excess fluid build-up in the body. The detailed uses of Frusidip Tablet are as follows:

  • Treatment of fluid retention (oedema): Frusidip Tablet helps your body eliminate excess fluid that accumulates in the ankles, feet, legs, or abdomen due to heart failure, liver disease, or kidney issues.
  • Management of high blood pressure (hypertension): By removing excess salt and water from your bloodstream, Frusidip Tablet relaxes blood vessels, helping to lower blood pressure and reduce the risk of future heart attacks or strokes.

Key Benefits

Frusidip Tablet provides effective relief from excess fluid retention, helping reduce swelling and improve overall comfort. By removing excess fluid from the body and reducing strain on the heart and lungs, this medicine offers several key benefits:

  • Helps Reduce Swelling and Fluid Build-Up: Frusidip Tablet helps remove excess fluid that accumulates in the body, reducing swelling in areas such as the legs, ankles, and abdomen. This can help you feel lighter, more comfortable, and better able to carry out everyday activities.
  • Supports Easier Breathing: By helping clear excess fluid from the lungs, this medicine can relieve shortness of breath and chest discomfort caused by fluid congestion. This makes breathing easier during daily activities and can improve comfort while resting or sleeping.
  • Improves Daily Comfort and Mobility: Reducing fluid retention can lessen feelings of heaviness and discomfort, making it easier to move around and stay active. Improved mobility and physical comfort can contribute to a better quality of life and greater independence in daily routines.
Side effects of Frusidip Tablet
  • Consume controlled amounts of salt to raise sodium levels.
  • Eat fresh fruits like apples, berries, oranges, mangoes, and bananas.
  • Include fresh vegetables like broccoli, sweet potatoes, beets, okra, spinach, peppers, carrots, and edamame.
  • Choose frozen vegetables without added butter or sauce.
  • Drink electrolyte beverages like sports drinks or electrolyte solutions to replenish sodium and other electrolytes.
  • Avoid excessive salt intake, but allow for controlled increases as needed.
  • Monitor and manage underlying health conditions that may contribute to hyponatremia.

Directions for Use

Take Frusidip Tablet exactly as prescribed by your doctor to ensure safe and effective results. Follow these simple steps:

  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet.
  • Take this medicine with or without food. Taking it with food may help if you experience a mild upset stomach.
  • Try to take your dose in the morning, preferably before 4:00 PM, to avoid waking up during the night to use the bathroom.
  • Always follow your doctor's exact instructions regarding how and when to take your medication. Do not stop taking it suddenly, even if you feel better, without consulting your healthcare provider first.
     

How Frusidip Tablet Works

Frusidip Tablet is a combination medicine that contains two active ingredients working in harmony to manage fluid levels while keeping your body's essential minerals balanced. The first active ingredient, furosemide, works in the kidneys to block the absorption of sodium, chloride, and water. This causes your body to produce more urine, rapidly flushing out the excess fluid that causes swelling and high blood pressure. However, this process can also cause your body to lose potassium, an important mineral for heart and muscle function. The second active ingredient, spironolactone, addresses this potassium loss. It is a potassium-sparing water pill that prevents your body from absorbing too much sodium while keeping your potassium levels from dropping too low. Together, these two ingredients ensure efficient fluid removal while maintaining a safer balance of vital electrolytes in your bloodstream.
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Alcohol

Caution

You are recommended not to consume alcohol along with Frusidip Tablet to avoid unpleasant side effects.

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Pregnancy

Unsafe

Frusidip Tablet must not be taken during pregnancy.

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Breast Feeding

Unsafe

Breastfeeding must be avoided during treatment with Frusidip Tablet.

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Driving

Unsafe

It is not recommended to drive after taking Frusidip Tablet as it may occasionally cause drowsiness due to orthostatic hypotension (sudden drop in blood pressure on standing from a lying position).

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Liver

Caution

Frusidip Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending upon your current liver conditions.

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Kidney

Caution

Frusidip Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. Your doctor may adjust your dose depending upon your current kidney conditions.

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Children

Unsafe

Frusidip Tablet is not recommended for children below 12 years of age.

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Heart

Safe if prescribed

Frusidip Tablet is safe for use in heart patients if recommended by the physician.

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Geriatrics

Caution

Frusidip Tablet should be used under caution in geriatric patients. Please consult your physician.

What if I have taken an overdose of Frusidip Tablet

Do not take more than the prescribed dose of Frusidip Tablet as it may cause serious side effects. If you suspect you have taken an overdose, seek immediate medical attention.

Diet & Lifestyle Advise

  • Watch your salt intake: High-sodium diets cause your body to hold onto water, which fights against the benefits of Frusidip Tablet. Avoid processed foods and do not add extra salt to your meals.
  • Be careful with potassium: Because one of the ingredients in Frusidip Tablet helps your body hold onto potassium, you should avoid taking potassium supplements or using salt substitutes that contain potassium, unless specifically told to do so by your doctor.
  • Stay hydrated safely: Drink the amount of fluids recommended by your doctor. Do not drastically increase or decrease your fluid intake without medical advice.
  • Monitor your weight daily: Weigh yourself every morning at the same time (after using the bathroom but before eating). A sudden, rapid increase in weight can mean your body is holding onto fluid again, which you should report to your doctor.

Have a query?

How Soon It Starts Working

  • The time required for Frusidip Tablet to start to work: Frusidip Tablet ideally shows its action within 1 hour after administration.
  • The time for which the effects of Frusidip Tablet last: The duration of action for Frusidip Tablet is unknown.

What if you forget to take Frusidip Tablet

If you miss a dose of Frusidip Tablet, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Storage

• Store Frusidip Tablet tablets at room temperature, ideally between 15°C and 30°C (59°F to 86°F). •Keep the medicine in its original container to protect it from direct light, moisture, and extreme heat.

Drug Warnings

  • Change positions slowly: To prevent dizziness or fainting, take your time when standing up from a sitting or lying position.
  • Schedule your doses wisely: Take your medicine early in the day so that the frequent urination does not disrupt your nighttime sleep.
  • Expect regular lab work: Your doctor will need to perform regular blood tests to check your kidney function and monitor your potassium and sodium levels. Keep all your lab appointments.
  • Limit direct sun exposure: This medicine can make your skin more sensitive to sunlight, increasing your risk of sunburn. Wear protective clothing and sunscreen when outdoors.
  • Avoid alcohol: Drinking alcohol while taking this medicine can cause a sudden drop in blood pressure, leading to severe dizziness or fainting.
     

Drug-Drug Interactions

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Drug-Drug Interactions

  • ACE inhibitors and potassium supplements: Taking these alongside Frusidip Tablet can cause dangerously high potassium levels in your blood.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs): These pain relievers can reduce the fluid-clearing effects of Frusidip Tablet and increase the risk of kidney damage.
  • Other blood pressure-lowering medicines: Combining these may cause your blood pressure to drop too low, resulting in severe dizziness.

Drug-Food Interactions

  • Potassium-rich foods and salt substitutes: Eating excessive amounts of bananas, oranges, or leafy greens or using potassium-based salt substitutes may lead to abnormally high blood potassium levels.

Drug-Disease Interactions

  • Severe kidney disease: If your kidneys are not producing urine, taking this medicine can lead to dangerous accumulations of the drug and fluids.
  • Severe liver damage: Patients with severe liver issues must be monitored closely, as rapid shifts in fluid levels can trigger serious brain complications.
  • Diabetes: This medicine may affect your blood sugar levels, requiring closer monitoring of your glucose readings.
  • Gout: Frusidip Tablet can increase uric acid levels in your blood, potentially triggering painful gout attacks.
     
Furosemide + SpironolactoneCisapride
Critical
Furosemide + SpironolactoneMorphine
Severe

Drug-Drug Interactions

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Furosemide + SpironolactoneCisapride
Critical
How does the drug interact with Frusidip Tablet:
Using Cisapride together with Frusidip Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although Frusidip Tablet and Cisapride can cause an interaction, it can be taken if a doctor prescribes it. Consult a doctor if you develop dizziness, lightheadedness, fainting, or fast or pounding heartbeats. Do not stop using any medications without talking to a doctor.
Furosemide + SpironolactoneMorphine
Severe
How does the drug interact with Frusidip Tablet:
Taking spironolactone with morphine may increase the blood levels and side effects of morphine.

How to manage the interaction:
Co-administration of Morphine with Spironolactone can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed, and motor coordination make sure to contact a doctor. Do not stop using any medications without consulting a doctor.
Furosemide + SpironolactoneQuinapril
Severe
How does the drug interact with Frusidip Tablet:
Using quinapril together with spironolactone may cause hyperkalemia (increase the levels of potassium in your blood).

How to manage the interaction:
Although taking spironolactone and quinapril together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as weakness, confusion, numbness or tingling, and uneven heartbeat. Do not stop using any medications without consulting doctor.
Furosemide + SpironolactoneValsartan
Severe
How does the drug interact with Frusidip Tablet:
Using spironolactone together with valsartan may increase potassium levels in the blood.

How to manage the interaction:
Although taking spironolactone and valsartan together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor immediately if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without consulting a doctor.
Furosemide + SpironolactoneLosartan
Severe
How does the drug interact with Frusidip Tablet:
Coadministration of Losartan with Spironolactone can increase potassium levels in blood which can lead to severe conditions like kidney problems and irregular heart rhythm.

How to manage the interaction:
Taking Losartan with Spironolactone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feeling of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctor's advice.
Furosemide + SpironolactoneNeomycin
Severe
How does the drug interact with Frusidip Tablet:
Coadministration of Frusidip Tablet and Neomycin can increase the risk of kidney damage and other side effects.

How to manage the interaction:
Although Frusidip Tablet and Neomycin can cause an interaction, it can be taken if a doctor prescribes it. Do not stop using any medications without talking to a doctor.
Furosemide + SpironolactoneTelmisartan
Severe
How does the drug interact with Frusidip Tablet:
Taking spironolactone with telmisartan may increase potassium levels in the blood.

How to manage the interaction:
Although there is a possible interaction, telmisartan can be taken with spironolactone if prescribed by the doctor. Consult the prescriber if you experience symptoms of high potassium such as nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Do not discontinue the medications without consulting a doctor.
Furosemide + SpironolactoneColchicine
Severe
How does the drug interact with Frusidip Tablet:
Coadministration of colchicine and Spironolactone increases blood levels of colchicine and its side effects.

How to manage the interaction:
Although taking Colchicine and Spironolactone together may result in an interaction, they can be taken together if a doctor prescribes it. However, contact a doctor immediately if you experience nausea, vomiting, abdominal pain, numbness or tingling in your hands and legs, muscle pain, or weakness. Do not discontinue any medication without consulting a doctor.
Furosemide + SpironolactoneDroperidol
Severe
How does the drug interact with Frusidip Tablet:
Coadministration of Frusidip Tablet and Droperidol can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although Frusidip Tablet and Droperidol can cause an interaction, it can be taken if a doctor prescribes it. Consult a doctor if you develop sudden dizziness, lightheadedness, fainting, fast or pounding heartbeats, weakness, tiredness, confusion, muscle pain, cramps, nausea, or vomiting. Do not stop using any medications without talking to a doctor.
Furosemide + SpironolactonePotassium chloride
Severe
How does the drug interact with Frusidip Tablet:
Taking Spironolactone with Potassium chloride may increase potassium levels in the blood which can lead to kidney problems and abnormal heart rhythm.

How to manage the interaction:
Taking Potassium chloride with Spironolactone can result in an interaction, it can be taken if a doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feeling of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

Frusidip Tablet is a combination medicine used to treat hypertension (high blood pressure) and oedema (fluid retention). It helps the body remove excess fluid through urine, reducing swelling and helping lower blood pressure.
Frusidip Tablet works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease.
No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and not recommend discontinuing it.
Yes. While taking Frusidip Tablet, regular monitoring of blood pressure, kidney function, and electrolyte levels (such as potassium and sodium) is important. Your doctor may recommend blood tests within the first few weeks of treatment and periodically thereafter, especially if you have kidney disease or other medical conditions.
If your leg (foot, ankle) or any other body part is swelling, you need to visit a physician or cardiologist who could perform an ultrasound examination of your leg veins and an ultrasound of your heart (echocardiogram-ECG).
Store Frusidip Tablet at room temperature, in a dry place. Keep out of sight and reach of children.
Do not take Frusidip Tablet if you are allergic to any of its components, have low blood pressure (less than 90 mm of Hg), have had a heart attack, or have kidney disease (with creatinine clearance less than 30 mL/min). Besides this, it is contraindicated in cardiogenic shock (sudden stopping of blood flow to the heart), and aortic stenosis (heart valve problem).
Yes, Frusidip Tablet is safe if taken in the dose and duration prescribed by the doctor.
Yes, Frusidip Tablet may cause dizziness, especially when standing up quickly due to a drop in blood pressure. If you feel dizzy, sit or lie down until you feel better and rise slowly from sitting or lying positions. Avoid driving or operating machinery if affected. Contact your doctor if the dizziness is severe or persistent.
Frusidip Tablet contains furosemide which may increase uric acid levels leading to gout. Consult the doctor if you experience sudden severe pain in a joint (usually your big toe).
It is not recommended to take Frusidip Tablet late in the day. Because it increases urination, taking it close to bedtime will likely disrupt your sleep. It is best to take it in the morning. Talk to your doctor or pharmacist if you need to adjust your schedule.
Yes, this is how the medicine works to rid your body of excess fluid. You will likely notice an increase in urination, especially during the first few hours after taking a dose. This effect usually becomes more manageable over time.
You should avoid taking potassium supplements or using potassium-based salt substitutes unless your doctor explicitly prescribes them. One of the active ingredients in Frusidip Tablet helps your body retain potassium, and adding more could lead to dangerously high levels.
It is best to avoid or strictly limit alcohol while taking Frusidip Tablet. Alcohol can increase the blood pressure-lowering effects of this medicine, making you feel extremely dizzy, lightheaded, or faint.
This medicine is generally not recommended during pregnancy unless your doctor decides the benefits outweigh the risks. It can affect fluid balance and blood flow to the placenta. If you are pregnant or planning to become pregnant, talk to your doctor.
You should notice an increase in urination within 1 to 2 hours after taking your dose. However, it may take several days or weeks of consistent use to notice a significant reduction in swelling or improvement in your blood pressure.

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Country of origin

India
Other Info - FR52687
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