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compositionComposition:HUMAN NORMAL IMMUNOGLOBULIN-5%W/V
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Prescription Medicine
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Gamma First Injection is used to treat immunoglobulin (antibody) deficiency and certain inflammatory disorders. It contains Human normal immunoglobulin which helps the body fight against infections and works the same way as natural immunoglobulins. In some cases, this medicine may cause side effects such as injection site reactions, headache, fever, flu-like symptoms, and throat tightness. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

HUMAN NORMAL IMMUNOGLOBULIN-5%W/V

Manufacturer/Marketer :

Celon Laboratories Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Gamma First Injection

Gamma First Injection is an injection used to protect the body against infections and to treat certain inflammatory conditions. It is prescribed for people whose immune systems do not make enough of their own protective antibodies. It is also used to treat specific autoimmune disorders where the body mistakenly attacks its own healthy tissues.

This medicine is given regularly, with the frequency depending on your specific condition and how your body responds to treatment. Because it is given as an injection or infusion, its absorption is not affected by food, though drinking plenty of fluids before your treatment is highly recommended. Incorporating simple habits like practising good hand hygiene and avoiding close contact with sick individuals can further support your immune health.

While taking Gamma First Injection , some people may experience mild side effects like headaches, chills, or redness at the injection site. It is important to watch for more serious symptoms, such as severe back pain, a sudden decrease in urination, or chest discomfort, and consult your doctor immediately if these occur.

Before you begin treatment, talk to your doctor if you have pre-existing kidney disease, diabetes, high blood pressure, or a history of blood clots. Do not take this medicine if you have had a severe allergic reaction to immunoglobulin therapies in the past, or if you have selective IgA deficiency with anti-IgA antibodies.

This medicine can interfere with live virus vaccines, making them less effective. Avoid drinking alcohol or smoking during treatment, as they can worsen side effects like dehydration and headaches. If you are pregnant, breastfeeding, or an older adult, consult your doctor or pharmacist to discuss the risks and benefits before starting this therapy.

Uses of Gamma First Injection

Gamma First Injection is used in the treatment of Immunoglobulin deficiency and inflammatory disorders. The detailed use of Gamma First Injection is as follows:

  • Primary Immunodeficiency Diseases (PIDD): Gamma First Injection provides necessary antibodies to protect individuals whose bodies cannot produce enough of their own to fight off bacteria and viruses.
  • Idiopathic Thrombocytopenic Purpura (ITP): It helps raise low platelet counts in the blood, reducing the risk of severe bruising or dangerous bleeding episodes.
  • Guillain-Barré Syndrome: Gamma First Injection helps reduce nerve inflammation, which helps speed up recovery and restores muscle strength.
  • Kawasaki Disease: It is used to lower severe blood vessel inflammation, helping prevent long-term damage to the heart's blood vessels.
  • Chronic Inflammatory Demyelinating Polyneuropathy (CIDP): It protects the protective covering of nerves from being damaged by the immune system, preserving muscle strength and coordination.

Key Benefits

Gamma First Injection helps strengthen the body's immune defences and manage certain autoimmune and nerve conditions.

The following are the benefits of Gamma First Injection :

  • Helps reduce the frequency of serious infections.
  • Supports a stronger immune system in people with immune deficiencies.
  • Improves muscle strength and physical mobility in certain nerve disorders.
  • Reduces symptoms caused by an overactive immune response.
  • Promotes faster recovery and better day-to-day functioning.
  • Provides long-term support for immune and neurological health.

Directions for Use

  • This medicine is given as an injection under the skin (subcutaneously) or infused directly into a vein (intravenously).
  • Most often, a healthcare professional will inject or infuse this medicine in a hospital, clinic, or doctor's office.
  • In some cases, you or a caregiver may be trained to inject the medicine at home. Always follow the step-by-step training provided by your medical team.
  • Before injecting, look at the liquid in the vial. It should be clear or slightly yellow. Do not use it if it looks cloudy, is discoloured, or contains visible floating particles.
  • If you are injecting under the skin, choose a different injection spot each time to help prevent skin irritation or pain.
  • Always follow your doctor's exact instructions regarding your schedule and the rate at which the medicine is injected.

How Gamma First Injection Works

Gamma First Injection contains Human normal immunoglobulin, which works by supplying your body with healthy antibodies obtained from donor blood. Antibodies are crucial proteins that the immune system normally uses to recognise and destroy foreign invaders like bacteria and viruses. If your body does not make enough antibodies, this medicine acts as a direct replacement to help fight off infections. In autoimmune or inflammatory conditions, your immune system mistakenly attacks healthy cells. In these cases, the healthy antibodies in Gamma First Injection help block or neutralise the harmful antibodies causing the attack, lowering inflammation and preventing further tissue damage.
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Alcohol

Safe if prescribed

Gamma First Injection may not interact with alcohol. However, limit or avoid consumption of alcohol to avoid possible side effects.

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Pregnancy

Safe if prescribed

Inform your doctor if you are pregnant or planning pregnancy before receiving Gamma First Injection . Your doctor will assess the benefits and the risks before prescribing.

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Breast Feeding

Safe if prescribed

Inform your doctor if you are breastfeeding before receiving Gamma First Injection . Your doctor will assess the benefits and the risks before prescribing.

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Driving

Caution

Gamma First Injection may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy after receiving this medicine.

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Liver

Caution

Gamma First Injection should be used with caution in patients with liver diseases. Your doctor may adjust the dose if necessary based on your condition.

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Kidney

Caution

Gamma First Injection should be used with caution in patients with kidney diseases. Your doctor may adjust the dose if necessary based on your condition.

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Children

Safe if prescribed

Gamma First Injection can be safely used in children when prescribed.

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before using Gamma First Injection . Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Limited information available for use of Gamma First Injection in elderly patients. Please consult your doctor.

What if I have taken an overdose of Gamma First Injection

Because this medicine is typically managed by healthcare professionals, an overdose is highly unlikely. However, if you self-inject and suspect you have used too much, seek emergency medical care or call your doctor right away.

Diet & Lifestyle Advise

  • Prioritise Hydration: Drink plenty of water or clear fluids before, during, and after your infusion. Proper hydration helps protect your kidneys from damage and can significantly lower your risk of getting a severe headache.
  • Practice Infection Prevention: Since this therapy is used for immune support, continue to wash your hands regularly, avoid close contact with people who are sick, and stay up to date on non-live vaccines recommended by your doctor.
  • Maintain a Balanced Diet: Eat a nutrient-rich diet with plenty of fruits, vegetables, and lean proteins to support your body's healing processes and overall strength.
  • Track Your Symptoms: Keep a health journal to record the dates of your injections, the site used, and any symptoms or side effects you notice. Share this log with your medical team.
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How Soon It Starts Working

  • The time required for Gamma First Injection to start to work: Gamma First Injection ideally shows its action within 30 to 60 minutes after administration.
  • The time for which the effects of Gamma First Injection last: The effect of Gamma First Injection lasts for 3 to 4 weeks.

What if you forget to take Gamma First Injection

If you miss an appointment for your infusion or forget to inject your scheduled dose at home, contact your doctor or healthcare provider immediately to reschedule. Do not inject a double dose to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight.• Keep this medicine out of the sight and reach of children.• Cold chain - To be stored in cold places at 2ºC to 8ºC.
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Keep Refrigerated. Do not freeze.

Drug Warnings

  • Check the Medicine: Always inspect the liquid before injecting. It should be clear or pale yellow. If it is cloudy or contains particles, do not inject it.
  • Do Not Shake: Avoid shaking the vial, as this can cause foaming and ruin the active proteins. Gently swirl the vial if needed.
  • Infuse Slowly: Ensure the infusion speed is kept slow, especially during the first half-hour of your session, to minimise side effects like headache or chills.
  • Rotate Injection Sites: If you are self-injecting under the skin, change your injection site every time to protect your skin tissues.
  • Delay Live Vaccines: Talk to your doctor before getting any vaccinations. This medicine can make live virus vaccines (like MMR or chickenpox) ineffective for several months after your last dose.
  • Watch Your Kidneys: Have your kidney function monitored regularly by your doctor, as this medicine can occasionally put strain on the kidneys.

verifiedApollotooltip
  • Live Vaccines (e.g., measles, mumps, rubella, varicella): May decrease the effectiveness of live vaccines if given within several months of this therapy.
  • Other Medicines(e.g., ibuprofen, gentamicin, furosemide): Taking this medicine alongside other drugs that can cause kidney strain may increase your risk of kidney damage.

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verifiedApollotooltip
  • No clinically significant food or drink interactions are commonly recognized with this medicine.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[IMMUNIZING AGENTS]

FAQs

Gamma First Injection is used to treat immunoglobulin (antibody) deficiency and certain inflammatory disorders.
The Gamma First Injection contains Human normal immunoglobulin, which helps restore the deficient immunoglobulins or antibodies in the body. Antibodies are an essential part of the immune system that help to reduce infection and inflammation. They act by identifying, attacking, and thereby destroying the antigen or foreign body that has entered or is present in the body.
Gamma First Injection may alter some blood test results for a certain time, so inform your doctor that you have Gamma First Injection before undergoing blood tests. Taking any vaccines (especially live vaccines) at least three months after taking Gamma First Injection is not recommended as this medicine may make the vaccines less effective.
Gamma First Injection should be used with caution in patients with diabetes if this medicine is given as an infusion, as it may alter blood sugar levels. Gamma First Injection doesn't contain sugar; however, it can be diluted in a special sugar solution before giving the infusion.
Gamma First Injection is usually well-tolerated. However, some patients may experience side effects such as swelling or hardening at the injection site and headache, pain in the face, back, arms, legs, joints, or neck, fever, flu-like illness (runny nose and sore throat), blisters in the mouth, and throat, and throat tightness. If any side effects persist or get worse, inform your doctor immediately.
It is a condition in which there is a decrease in antibody levels in the body due to decreased ability or inability to produce enough antibodies. It can be present from birth (primary) or acquired during the later stages of life (secondary).
Certain vaccinations, such as those for chickenpox, measles, mumps, and rubella, may become less effective when administered with Gamma First Injection . Therefore, before receiving any vaccinations, inform your doctor if you are allergic to Gamma First Injection . Let your doctor know that you are taking Gamma First Injection . And also inform your doctor if you are breastfeeding, pregnancy or planning pregnancy.
No, you should not discontinue using Gamma First Injection without consulting your doctor, even if you feel fine. Stopping the usage of Gamma First Injection early can increase the risk of infections. Always follow your doctor's instructions and complete the prescribed course of treatment to ensure the best outcome.
The effects of Gamma First Injection can vary depending on the individual and the condition being treated. Generally, it may take up to 4 weeks of regular therapy to notice a steady improvement in your symptoms. Therefore, complete the full course of treatment as prescribed by your doctor.
Yes, Gamma First Injection can cause kidney damage but not in everyone. Patients having a pre-existing kidney problem, hypovolemia (a decrease in the volume of circulating blood) and diabetes are at risk of developing kidney failure. Additionally, patients who are overweight, above 65 years of age and who are taking medicines that can cause kidney damage are also at risk of developing kidney failure. Therefore, please inform your doctor if you have any pre-existing kidney problems.
No, hair loss is not a commonly reported side effect of Gamma First Injection . If you experience hair loss, it might be due to some other underlying problem. Please consult your doctor if bothers you.
Gamma First Injection benefits people with weakened immune systems, such as those who have undergone bone marrow transplants or have severely reduced antibody-forming capacity. It can also treat or prevent infections who are suffering with measles, hepatitis, and mumps. It is used for patients with primary immunodeficiency syndromes (PID) and acquired or secondary immunodeficiency (SID). Please consult your doctor if you have any concerns.
If you are pregnant, take your doctor’s advice before using Gamma First Injection . Your doctor will assess the benefits and risks of Gamma First Injection before prescribing.
Store Gamma First Injection in a refrigerator (2 - 8°C). Do not freeze. Protect it from light. Keep out of reach of children.
Gamma First Injection is given parenterally, meaning it is injected under the skin (subcutaneously) or infused directly into a vein (intravenously). It is usually given by a trained healthcare professional, though some patients may be taught how to inject it at home. Talk to your doctor about the safest way to receive your treatment.
You should avoid receiving live vaccines, such as the measles, mumps, rubella (MMR), or chickenpox vaccine, while receiving Gamma First Injection , as the medicine can make these vaccines less effective. Non-live vaccines are generally safe but may not work as well. Always talk to your doctor or pharmacist before scheduling any vaccinations.
Headaches are a very common side effect of Gamma First Injection infusions. They are often caused by the speed of the infusion or mild dehydration. Drinking plenty of water before and during your treatment can help prevent this. If your headache is severe, lasts a long time, or is accompanied by a stiff neck and fever, talk to your doctor immediately.
If you miss a scheduled dose or infusion, contact your healthcare provider as soon as possible to reschedule your appointment. Maintaining a regular schedule is important for keeping your antibody levels stable. Do not try to double your next dose. Talk to your doctor if you have questions about your schedule.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Plot No 264, Patrika Nagar Madhapur, Hitech City Hyderabad, Telangana India - 500081
Other Info - GAM0148
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