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compositionComposition:VERICIGUAT-2.5MG
prescription
Prescription Medicine
info
Gantra 2.5 mg Tablet 14's
Gantra 2.5 mg Tablet 14's
Gantra 2.5 mg Tablet 14's

Gantra 2.5 mg Tablet 14's is used to manage Systolic heart failure to reduce mortality and hospitalizations. It contains Vericiguat, which relaxes the blood vessels in the lungs to allow blood to flow easily. This medication can cause fetal harm when administered to a pregnant woman. It is critical not to become pregnant while undergoing therapy and for one month after the treatment. Using effective contraceptive methods is recommended while in therapy with it. Contact your doctor immediately if you or your partner becomes pregnant while undergoing therapy. Breastfeeding is usually not advised during this treatment.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

VERICIGUAT-2.5MG

Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Gantra 2.5 mg Tablet 14's

Gantra 2.5 mg Tablet 14's is used to reduce the risk of death and the need for hospitalization in adults with heart failure. Heart failure is a condition in which the heart is unable to pump blood as effectively as it should.

Gantra 2.5 mg Tablet 14's contains Vericiguat, which works by relaxing the blood vessels in the lungs to allow blood to flow easily.

Sometimes, Gantra 2.5 mg Tablet 14's may cause hypotension, anaemia, dizziness and light-headedness as side effects. Most of these side effects are temporary, do not require medical attention, and gradually resolve over time. However, if the side effects persist or worsen, contact your doctor.

Before taking Gantra 2.5 mg Tablet 14's, inform your doctor about all your allergic to medicines or food. Gantra 2.5 mg Tablet 14's can cause fetal harm when administered to a pregnant woman. Using effective contraceptive methods is recommended while on therapy with Gantra 2.5 mg Tablet 14's. Breastfeeding is usually not advised during this treatment.

Uses of Gantra 2.5 mg Tablet 14's

Gantra 2.5 mg Tablet 14's is used in the management of systolic heart failure to reduce mortality and hospitalisations. The detailed uses of Gantra 2.5 mg Tablet 14's are as follows:

  • Chronic heart failure with reduced ejection fraction (HFrEF): Gantra 2.5 mg Tablet 14's is used in adults with symptomatic chronic heart failure who have a left ventricular ejection fraction (LVEF) less than 45%. It helps the heart pump blood more efficiently by stimulating soluble guanylate cyclase (sGC), an enzyme involved in cardiovascular regulation.
  • Post-hospitalization heart failure management: Gantra 2.5 mg Tablet 14's is prescribed to reduce the risk of cardiovascular death and heart failure-related hospitalizations in patients who have recently been hospitalized for heart failure or required outpatient intravenous (IV) diuretics.
  • Improved blood circulation: Gantra 2.5 mg Tablet 14's works by relaxing blood vessels and improving blood flow, which helps reduce the workload on the heart and alleviates symptoms like breathlessness, fatigue, and swelling.

Key Benefits

  • Gantra 2.5 mg Tablet 14's contains Vericiguat, a soluble guanylate cyclase (sGC) stimulator.
  • It is primarily used in adults who have symptoms of chronic (long-term) heart failure, have recently been hospitalised or require intravenous (IV) medications.
  • Gantra 2.5 mg Tablet 14's is also used in patients who have an ejection fraction (amount of blood pumped with each heartbeat of less than 45 per cent) to reduce the risk of death and the need to be hospitalized.
  • Vericiguat works by relaxing the blood vessels in the lungs to allow blood to flow easily.
Side effects of Gantra 2.5 mg Tablet
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Directions for Use

  • Take Gantra 2.5 mg Tablet 14's with food or as advised by your doctor.
  • It is recommended to take Gantra 2.5 mg Tablet 14's once daily; however, follow your doctor’s advice regarding the dosage and duration.
  • Swallow the tablet as a whole with water. Tablets may be crushed and mixed with water for patients who have difficulty swallowing.
  • Do not chew Gantra 2.5 mg Tablet 14's.

How Gantra 2.5 mg Tablet 14's Works

Gantra 2.5 mg Tablet 14's contains Vericiguat, which works by relaxing the blood vessels in the lungs to allow blood to flow easily.
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Alcohol

Unsafe

Intake of alcohol should be avoided with Gantra 2.5 mg Tablet 14's.

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Pregnancy

Unsafe

Gantra 2.5 mg Tablet 14's should not be used during pregnancy. So, inform your doctor if you are pregnant or suspect pregnancy. You or your partner must use a reliable form of contraception to prevent pregnancy while taking Gantra 2.5 mg Tablet 14's.

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Breast Feeding

Unsafe

You should not breastfeed while taking this medication.

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Driving

Unsafe

Gantra 2.5 mg Tablet 14's may cause dizziness. So, driving vehicles and operating machinery which requires concentration should be avoided.

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Liver

Caution

Caution is advised. Gantra 2.5 mg Tablet 14's has not been studied in patients with severe hepatic impairment. Inform your doctor before using Gantra 2.5 mg Tablet 14's if you have liver problems or a history of liver conditions.

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Kidney

Caution

Caution is advised. Inform your doctor before using Gantra 2.5 mg Tablet 14's if you have kidney problems or a history of kidney conditions.

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Children

Unsafe

The safety and effectiveness of Gantra 2.5 mg Tablet 14's in children have not been established.

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Heart

Safe if prescribed

Gantra 2.5 mg Tablet 14's is specifically approved for patients with chronic heart failure and reduced ejection fraction. It help lower the risk of cardiovascular death and hospitalization by improving blood vessel function and heart performance. Always follow your doctor’s guidance to ensure it's suitable for your condition.

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Geriatrics

Caution

Gantra 2.5 mg Tablet 14's can be used in geriatric patients with chronic heart failure, but careful monitoring is essential. Older adults may be more sensitive to side effects like low blood pressure or dizziness.

What if I have taken an overdose of Gantra 2.5 mg Tablet 14's

Do not take more than the prescribed dose. Using more medication will not improve your symptoms; rather, they may cause poisoning or serious side effects. If you suspect that you may have overdosed on Gantra 2.5 mg Tablet 14's, please go to the emergency department of the closest hospital or nursing home.

Diet & Lifestyle Advise

  • Follow a cholesterol-lowering diet.
  • Consume low salt and a low-fat diet.
  • Exercise regularly. It helps in maintaining proper weight and lowers cholesterol.
  • Limit salt and sugar intake.
  • Avoid smoking and alcohol consumption.
  • Choose healthy fats and cut down on trans fats.
  • Include omega-3 fatty acids, fibre-rich food, fruits, and vegetables.
  • Get active by doing physical activities such as swimming, brisk walking, or jogging. Take the stairs instead of elevators/lifts.

Have a query?

How Soon It Starts Working

  • The time required for Gantra 2.5 mg Tablet 14's to start to work: Gantra 2.5 mg Tablet 14's ideally shows its action within 1 hour after administration. 
  • The time for which the effects of Gantra 2.5 mg Tablet 14's last: The duration of action for Gantra 2.5 mg Tablet 14's is unknown.

What if you forget to take Gantra 2.5 mg Tablet 14's

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with the regular dosing schedule. Do not take a double dose.

Storage

• Store in a cool and dry place away from sunlight.• Keep Gantra 2.5 mg Tablet 14's out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Before taking Gantra 2.5 mg Tablet 14's, let your doctor know about any allergies or hypersensitivities to medicines or food.
  • Do not use Gantra 2.5 mg Tablet 14's and any medication for erectile dysfunction (male impotence) simultaneously.
  • Please check with your doctor before using Gantra 2.5 mg Tablet 14's if you have/had anaemia, low blood pressure, or any severe medical illness.
  • Before starting Gantra 2.5 mg Tablet 14's, inform your doctor about your medical history and ongoing therapies to rule out potential adverse effects or interactions.
  • Gantra 2.5 mg Tablet 14's can cause fetal harm when administered to a pregnant woman.
  • Using effective contraceptive methods is recommended while on therapy with Gantra 2.5 mg Tablet 14's.
  • Breastfeeding is usually not advised during this treatment.
  • Gantra 2.5 mg Tablet 14's is not recommended for use in children below 16 years.

Drug-Drug Interactions

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Drug-Drug interactions: Gantra 2.5 mg Tablet 14's may interact with medicines used for erectile dysfunction (e.g. avanafil, sildenafil, vardenafil, tadalafil) and certain medications used to treat pulmonary arterial hypertension (e.g. riociguat)

Drug-Food Interactions: Avoid the consumption of alcoholic beverages.

Drug-Disease Interactions: Inform your doctor if you have/had anaemia (low red blood cells), low blood pressure, and liver or kidney impairment.

No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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FAQs

Gantra 2.5 mg Tablet 14's is used to reduce the risk of death and the need for hospitalization in adults with heart failure.
Gantra 2.5 mg Tablet 14's contains Vericiguat, which works by relaxing the blood vessels and allowing blood to flow easily. As a result, the heart can pump more efficiently and does not have to work as hard. As a result, it helps to lower the risk of death and hospitalization in people with heart failure.
No, you should not combine Gantra 2.5 mg Tablet 14's with an erectile dysfunction medicine such as sildenafil or tadalafil since it may interfere with the blood pressure-lowering action of Gantra 2.5 mg Tablet 14's.
Yes, dizziness or light-headedness is the most common side effect encountered while using Gantra 2.5 mg Tablet 14's. Please take sufficient rest. If the problem persists, consult your doctor.
Gantra 2.5 mg Tablet 14's may not be recommended for patients with hypotension (low blood pressure); inform your doctor before using Gantra 2.5 mg Tablet 14's if you have a history of hypotension.
Gantra 2.5 mg Tablet 14's may not be recommended for patients with severe anaemia (does not have enough healthy red blood cells); inform your doctor before using Gantra 2.5 mg Tablet 14's if you have ever had anaemia.
Entresto and Gantra 2.5 mg Tablet 14's are both medications used to manage heart failure, but they work in different ways and have distinct uses. Entresto contains sacubitril/valsartan, while Gantra 2.5 mg Tablet 14's contains Vericiguat. Both medications have shown effectiveness in managing heart failure and reducing hospitalizations. The choice between them may depend on individual patient factors, such as medical history, current symptoms, and overall health. Ultimately, the decision between Entresto and Gantra 2.5 mg Tablet 14's should be made in consultation with your doctor, who can consider your medical history and needs.
Gantra 2.5 mg Tablet 14's should be taken once daily with food. The specific time of day is not as important as taking it consistently at the same time each day to maintain an even level in your blood. If you have any concerns or specific instructions from your healthcare provider, it is best to follow their guidance.
Gantra 2.5 mg Tablet 14's is primarily used to reduce the risk of cardiovascular death and heart failure hospitalization in patients with symptomatic chronic heart failure with reduced ejection fraction (HFrEF). While Gantra 2.5 mg Tablet 14's helps improve heart function by enhancing the production of cyclic guanosine monophosphate (cGMP), which relaxes blood vessels and reduces the workload on the heart, it does not directly improve ejection fraction.
Your doctor will determine the dosing of Gantra 2.5 mg Tablet 14's and prescribe the appropriate dose based on various factors, such as your medical condition, response to treatment, and ability to tolerate the medication.
No, Gantra 2.5 mg Tablet 14's should not be taken during pregnancy. It may cause fetal harm when administered to a pregnant woman. It is important to exclude pregnancy before starting treatment with Gantra 2.5 mg Tablet 14's and to use effective contraception during treatment and for at least one month after stopping the medication.
Vericiguat can lower blood pressure, and hypotension (low blood pressure) is a common side effect of this medication. If you experience symptoms such as dizziness or lightheadedness, taking precautions to avoid falls or injuries is essential. To cope with these symptoms, sit or lie down immediately if you feel dizzy, stay hydrated by drinking plenty of water, avoid standing for long periods, rise slowly from sitting or lying down positions, and avoid heavy lifting or bending. However, consult your healthcare provider for guidance if symptoms persist or worsen.
Heart failure can present a variety of symptoms, some of which may be subtle and easily overlooked. Here are some common symptoms to watch out for: shortness of breath with activity or when lying down, fatigue and weakness, swelling in the legs, ankles and feet, rapid or irregular heartbeat, wheezing, very fast weight gain from fluid buildup, nausea and lack of appetite, difficulty concentrating or decreased alertness, chest pain if a heart attack causes heart failure. If you or someone you know is experiencing these symptoms, it is essential to seek medical attention for proper evaluation and management.
Making positive lifestyle changes can significantly impact heart failure management and overall health. Some key lifestyle modifications that can make a difference are maintaining a healthy diet, regular exercise, weight management, managing stress, quitting smoking, limiting alcohol, and following medical advice.
A heart-healthy diet is designed to support cardiovascular health and reduce the risk of heart disease. Some key components of a heart-healthy diet are fruits and vegetables, limited added sugars, moderate alcohol intake, whole grains, lean proteins, and hydration. Following these guidelines can help protect your heart and improve your overall well-being.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Dr. Reddy'S Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, India.
Other Info - GAN0093

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