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  3. Gardenal Syrup 100 ml

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Gardenal Syrup 100 ml, Pack of 1 SYRUP
Gardenal Syrup 100 ml, Pack of 1 SYRUP
Gardenal Syrup 100 ml, Pack of 1 SYRUP
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Written By ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Gardenal Syrup belongs to the class of anticonvulsants and is used to treat or prevent epilepsy (seizures). It is also used as a sedative to relieve anxiety and as a hypnotic for the short-term management of insomnia (sleeplessness). It contains Phenobarbitone, which works by controlling the abnormal electrical activity in the brain, thereby preventing and managing seizures. Additionally, it helps calm overly active brain chemicals, promoting relaxation and sedation. In some cases, it may cause side effects such as drowsiness, dizziness, restlessness, nausea, vomiting, and headache. Before taking this medicine, you should inform your doctor if you are allergic to any of its components, if you are pregnant or breastfeeding, and provide details about any other medications you are taking or existing medical conditions.

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Synonym :

PHENOBARBITAL, FENOBARBITAL

Composition :

PHENOBARBITONE-20MG

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Gardenal Syrup

Gardenal Syrup belongs to the class of medicines known as 'anticonvulsants,' primarily used for the treatment or prevention of epilepsy (seizures). It is also used as a sedative to relieve anxiety and as a hypnotic for the short-term management of insomnia (sleeplessness). Epilepsy is a neurological disorder in which the nerves in the brain fail to function properly, resulting in seizures, unusual sensations or behaviour, and sometimes loss of consciousness.

Gardenal Syrup contains Phenobarbitone, which works by controlling abnormal electrical activity in the brain, thereby preventing and managing seizures. Additionally, it calms overactive chemicals in the brain, helping a person feel relaxed so the brain can function normally.

Take Gardenal Syrup exactly as prescribed. Your doctor will determine the appropriate dosage and timing based on your medical condition. Some patients taking Gardenal Syrup may experience side effects, including drowsiness, dizziness, restlessness, nausea, vomiting, and headache. Most of these side effects do not require medical attention and tend to resolve gradually over time. However, if the side effects persist or worsen, please consult your doctor.

Do not take Gardenal Syrup if you are allergic to Phenobarbitone or any of its ingredients. Use this medicine exactly as prescribed; do not change your dose or stop using it without consulting your doctor. If you need to stop using Gardenal Syrup , your doctor may gradually reduce your dose to prevent withdrawal symptoms. Tell your doctor before using Gardenal Syrup if you have liver disease, kidney disease, breathing problems (such as severe asthma or COPD), a history of substance use disorder, porphyria, or if you are taking anticoagulant medicines (like warfarin) or other sedatives. If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits with your doctor, as Phenobarbitone can affect fetal development and may pass into breast milk. Gardenal Syrup should only be used in children if specifically recommended and supervised by a doctor.

Uses of Gardenal Syrup

Gardenal Syrup is used in the treatment or prevention of epilepsy (seizures). The detailed uses of Gardenal Syrup are as follows:

  • Seizure Control:Gardenal Syrup is commonly prescribed for the long-term management of various types of seizures, including partial seizures, febrile seizures, and generalised tonic-clonic seizures.
  • Anxiety Relief:Gardenal Syrup is used as a sedative for the short-term relief of anxiety, particularly when a rapid calming effect is required.
  • Sleep Disorders:Gardenal Syrup acts as a hypnotic and may be used to manage insomnia or other sleep-related disturbances due to its sedative properties.
  • Withdrawal Management:Gardenal Syrup may be used to prevent withdrawal symptoms in individuals dependent on other barbiturates during discontinuation or tapering.
  • Hyperbilirubinemia Management:Gardenal Syrup is used to prevent or treat elevated bilirubin levels in newborns. It may also help reduce bilirubin levels in individuals with certain liver conditions, such as chronic intrahepatic cholestasis or congenital non-hemolytic unconjugated hyperbilirubinemia.

Directions for Use

  • Gardenal Syrup may be taken with or without food; taking it with food can help reduce stomach upset.
  • Shake the bottle well before each use to ensure the medicine is evenly mixed.
  • Measure the prescribed dose carefully using the provided measuring cup, syringe, or dropper.
  • Follow your doctor’s instructions on dosage and timing exactly to ensure safe and effective treatment.

Medicinal Benefits

Gardenal Syrup belongs to a group of medications known as anticonvulsants, primarily used for the treatment of various types of epilepsy except absence seizures. It contains Phenobarbitone, which works by controlling abnormal electrical activity in the brain, thereby preventing and managing seizures. Additionally, it calms overactive chemicals in the brain, helping a person feel relaxed so the brain can function normally. Gardenal Syrup is also used as a sedative to relieve anxiety and tension, and as a hypnotic for the short-term management of insomnia (sleeplessness).

How Gardenal Syrup Works

Gardenal Syrup contains Phenobarbitone, which works by controlling the abnormal electrical activity in the brain, thereby preventing and controlling seizures. Additionally, it calms the excited chemicals in the brain, allowing a person to feel relaxed and enabling the brain to function normally.

Storage

• Store in a cool and dry place away from sunlight.• Keep Gardenal Syrup out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Gardenal Syrup

Do not take more than the prescribed dose of Gardenal Syrup , as it may cause an overdose. The symptoms of an overdose include weak pulse, slow or shallow breathing, little or no urination, pinpoint pupils, cold or clammy skin, feeling cold, or fainting. If you suspect you have taken an overdose or notice any of these symptoms, please consult a doctor immediately.

Drug Warnings

Do not take Gardenal Syrup if you are allergic to phenobarbitone, other barbiturates, or any of its ingredients. This medicine can be habit-forming, so avoid prolonged use to prevent dependence and tolerance. Please do not stop taking it suddenly without your doctor's advice, as this may cause withdrawal symptoms like anxiety, hallucinations, or trouble sleeping. Gardenal Syrup is not recommended for people with severe asthma, COPD, severe liver disease, porphyria, or a history of addiction. Tell your doctor if you are pregnant, planning pregnancy, or breastfeeding, as seizure control is essential during pregnancy, and your doctor will decide if Gardenal Syrup is suitable. It should not be given to children without a doctor's recommendation, as it may impact learning and development. Always inform your doctor about any other health conditions you may have before using Gardenal Syrup .

Drug-Drug Interactions

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PhenobarbitalSodium oxybate
Critical
PhenobarbitalRitonavir
Critical

Drug-Drug Interactions

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PhenobarbitalSodium oxybate
Critical
How does the drug interact with Gardenal Syrup 100 ml:
Using Sodium oxybate together with Gardenal Syrup 100 ml may increase side effects (drowsiness, dizziness, lightheadedness, confusion, depression, low blood pressure, slow or shallow breathing, and impairment in thinking, judgment, and motor coordination).

How to manage the interaction:
Taking Sodium oxybate with Gardenal Syrup 100 ml is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
PhenobarbitalRitonavir
Critical
How does the drug interact with Gardenal Syrup 100 ml:
Taking Gardenal Syrup 100 ml with Ritonavir may significantly reduce the blood levels of ritonavir.

How to manage the interaction:
Taking Gardenal Syrup 100 ml with Ritonavir is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. If you notice any unusual symptoms consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
PhenobarbitalChlorpromazine
Critical
How does the drug interact with Gardenal Syrup 100 ml:
When Chlorpromazine is taken with Gardenal Syrup 100 ml, can change the drug levels and effects of both medications.

How to manage the interaction:
Taking Chlorpromazine with Gardenal Syrup 100 ml is not recommended, as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience unusual symptoms, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
PhenobarbitalVoriconazole
Critical
How does the drug interact with Gardenal Syrup 100 ml:
Using Voriconazole together with Gardenal Syrup 100 ml may significantly reduce the blood levels of voriconazole.

How to manage the interaction:
Taking Voriconazole with Gardenal Syrup 100 ml is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
PhenobarbitalIsavuconazole
Critical
How does the drug interact with Gardenal Syrup 100 ml:
When Isavuconazole is taken with Gardenal Syrup 100 ml, may decrease the blood levels of Isavuconazole, which may make Isavuconazole less effective.

How to manage the interaction:
Taking Isavuconazole with Gardenal Syrup 100 ml is not recommended it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
PhenobarbitalBedaquiline
Critical
How does the drug interact with Gardenal Syrup 100 ml:
Using Bedaquiline together with Gardenal Syrup 100 ml may reduce the blood levels of bedaquiline, which may decrease its effectiveness.

How to manage the interaction:
Taking Gardenal Syrup 100 ml with Bedaquiline is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
PhenobarbitalPraziquantel
Critical
How does the drug interact with Gardenal Syrup 100 ml:
Using praziquantel together with Gardenal Syrup 100 ml may significantly reduce the blood levels of praziquantel, which may make the medication less effective.

How to manage the interaction:
Taking Gardenal Syrup 100 ml with Praziquantel is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
PhenobarbitalPirfenidone
Critical
How does the drug interact with Gardenal Syrup 100 ml:
When Pirfenidone is taken with Gardenal Syrup 100 ml, it can decrease the effects of Pirfenidone.

How to manage the interaction:
Taking Pirfenidone with Gardenal Syrup 100 ml is not recommended but can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
PhenobarbitalNimodipine
Critical
How does the drug interact with Gardenal Syrup 100 ml:
When Nimodipine is taken with Gardenal Syrup 100 ml, it may decrease the blood levels of Nimodipine, which may make Nimodipine less effective in treating the condition.

How to manage the interaction:
Taking Nimodipine with Gardenal Syrup 100 ml is not recommended, as it can result in an interaction, but it can be taken if a doctor has advised it. However, consult the doctor if you experience any unusual symptoms while taking the therapy. Do not discontinue any medications without consulting the doctor.
PhenobarbitalRanolazine
Critical
How does the drug interact with Gardenal Syrup 100 ml:
When Ranolazine is taken with Gardenal Syrup 100 ml, may significantly reduce the blood levels of Ranolazine, which may make the medication ineffective or less effective.

How to manage the interaction:
Taking Gardenal Syrup 100 ml with Ranolazine can lead to an interaction, consult a doctor before taking it. They can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Quit smoking, as it can reduce the effectiveness of Gardenal Syrup , increase the risk of epileptic attacks, and damage the lungs. Stopping smoking is strongly recommended.
  • Include fruits and vegetables rich in antioxidants in your diet to support brain health and help reduce the risk of seizures.
  • Maintain a regular sleep schedule, aiming for 7–8 hours of sleep each night. Fatigue is a common trigger for seizures, so proper rest helps relax the brain.
  • Avoid alcohol, as it can increase the risk of epileptic attacks and interfere with seizure control.
  • Manage stress effectively and maintain emotional balance. Stress is known to trigger seizures, and people who maintain healthy stress levels often respond better to treatment.

Habit Forming

Yes

Therapeutic Class

ANTICONVULSANT

Gardenal Syrup Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Being barbiturates, Gardenal Syrup is a habit-forming medication that can cause drug dependence in them. The risks of dependence get enhanced when coupled with alcohol, so do not drink alcohol to get more reliable results.

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Pregnancy

Safe if prescribed

Follow all the directions given by your physician if you are taking Gardenal Syrup during pregnancy, as controlling seizures is very important at this time. The occurrence of a seizure can harm both the mother and the unborn baby. Inform your doctor if you are pregnant so they can prescribe the appropriate dose of this medicine.

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Breast Feeding

Caution

Gardenal Syrup can only be given to breastfeeding mothers if strongly suggested by the doctor.

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Driving

Caution

Gardenal Syrup may cause drowsiness, dizziness, and other symptoms that can affect a person's thinking ability, so avoid engaging in such activities.

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Liver

Unsafe

Gardenal Syrup is not recommended for use in patients with severe liver disease. Please discuss this with your doctor if you have any concerns.

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Kidney

Caution

Gardenal Syrup should only be used in patients with kidney disease if strongly suggested by a doctor.

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Children

Safe if prescribed

Gardenal Syrup is safe for children if prescribed by a doctor. Initially, the child may feel sleepy, but they will soon develop tolerance to the unpleasant effects of the medication.

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Heart

Gardenal Syrup can be used in heart patients only under strict medical supervision. Therefore please consult your doctor if you have any concerns.

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Geriatrics

Consult your doctor

Gardenal Syrup should be given to geriatrics only when prescribed by a doctor. If you have any concerns about using Gardenal Syrup for geriatrics, please consult a doctor.

Have a query?

FAQs

Gardenal Syrup belongs to the class of medicines known as 'anticonvulsants,' primarily used in the treatment or prevention of epilepsy (seizures). It is also used as a sedative to relieve anxiety and as a hypnotic for the short-term management of insomnia (sleeplessness).

Gardenal Syrup belongs to a class of medications known as barbiturate anticonvulsants/hypnotics. It works by controlling the abnormal electrical activity in the brain that occurs during a seizure. Additionally, it calms the excitatory chemicals in the brain, allowing a person to feel relaxed.

Yes, Gardenal Syrup is a habit-forming medicine that can cause serious drug addiction, so one should talk to their doctor before quitting it completely.

Being barbiturates, Gardenal Syrup is a habit-forming medicine that can cause drug addiction in them. The dangers of addiction increase when combined with alcohol, so do not consume alcohol to get better results.

Gardenal Syrup can be taken with or without food; however, there are chances of vomiting when taken on an empty stomach. It is better to take Gardenal Syrup with one glass of milk or after a meal to avoid stomach upset, or as suggested by your doctor.

No, do not stop taking Gardenal Syrup without confirming with the doctor, as it may worsen or cause a severe seizure. It is better to consult with the doctor, as they may be able to reduce the dosage before completely stopping it.

If you forget to take a dose of Gardenal Syrup , take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a forgotten dose.

Long-term side effects of Gardenal Syrup are changes in the soft tissues of the body. Symptoms include joint pain, discomfort, or thickening in certain areas, such as the palm or bottom of the foot. If you experience any of these symptoms, please consult your doctor.

Taking more than the recommended dose of Gardenal Syrup can lead to an overdose. Overdose symptoms include drowsiness, speech problems, jerky movements, jerky eye movements, loss of inhibition, reduced reflex response, low body temperature, low blood pressure and breathing problems. If you experience any of these symptoms, please consult your doctor immediately.

Gardenal Syrup is used in children to treat and prevent seizures. However, it can cause side effects such as nausea, vomiting, drowsiness, dizziness, and hyperactivity. It's essential to monitor your child for any unusual symptoms and consult your doctor if you have any concerns.

No, do not take folic acid while taking Gardenal Syrup . Because folic acid interacts with Gardenal Syrup and may decrease the levels of Gardenal Syrup in your body. Please consult your doctor if you have any concerns.

The duration for taking Gardenal Syrup depends on your specific condition and your doctor's recommendations. However, the exact duration should be determined by your doctor based on your response to Gardenal Syrup and any side effects you may experience. Therefore, it's essential to follow your doctor's instructions and do not stop taking Gardenal Syrup without consulting your doctor.

Yes, there is a test called the phenobarbital test that measures the level of phenobarbital in your blood. If you feel excessively sleepy and experience tremors, balance issues, or double vision, inform your doctor and have your levels checked.

Yes, Gardenal Syrup can cause withdrawal symptoms like hallucinations, twitching, anxiety, and trouble sleeping. Therefore, the dosage should be reduced gradually before being stopped altogether. And also inform your doctor before stopping Gardenal Syrup . However, if you experience any of these symptoms, please consult your doctor.

The common side effects of Gardenal Syrup are drowsiness, dizziness, restlessness, nausea, vomiting, and headache. Most of these side effects of Gardenal Syrup do not require medical attention and tend to resolve gradually over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

401, LSC, C-Block, Mohan Place Saraswati Vihar Delhi DL 110034 In
Other Info - GAR0445

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Reference

  1. https://pdf.hres.ca/dpd_pm/00048221.PDF
  2. https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=037c7532-7688-44fd-8c76-d25e8adf5fb5&type=display
  3. https://medlineplus.gov/druginfo/meds/a682007.html
  4. https://www.drugs.com/mtm/phenobarbital.html
  5. https://www.medicines.org.uk/emc/files/pil.4920.pdf
  6. https://www.webmd.com/drugs/2/drug-8689/phenobarbital-oral/details

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