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Gastobid Tablet is used to treat irritable bowel syndrome, peptic ulcers, and indigestion. It contains Trifluoperazine and Isopropamide which work by relaxing the muscles in the digestive tract and decreasing intestinal spasms. In some cases, this medicine may cause side effects such as nausea, dry mouth, constipation, sleepiness, weight gain, and dizziness. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Thrift Pharmaceuticals Pvt Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Gastobid Tablet

Gastobid Tablet is a prescription medication designed to manage functional gastrointestinal disorders, such as irritable bowel syndrome and peptic ulcers. It is formulated to calm painful spasms in your digestive tract and reduce the emotional tension that often triggers stomach distress. By treating both the physical gut spasms and the nervous system components, it helps restore digestive comfort.

For maximum benefits, you must take this medication consistently at the same times every day as directed by your doctor. It is typically taken with a glass of water, and you can take it with or without food. Combining this treatment with a balanced diet, smaller meals, and stress-reduction techniques can significantly improve your overall results.

While using this medicine, you may notice mild side effects such as dry mouth, blurred vision, or light drowsiness. However, you must seek medical attention immediately if you experience serious side effects like muscle stiffness, uncontrollable twitching, or difficulty urinating.

Talk to your doctor before starting this medicine if you have a history of heart issues, kidney disease, or glaucoma. Do not take this medication if you suffer from severe urinary retention, a severe blockage in your stomach or intestines, or if you are allergic to any of its components.

This medicine can interact with alcohol and sleep medications, which can significantly worsen drowsiness and other side effects. Tell your doctor about all prescription medicines, over-the-counter products, and herbal supplements you are taking before starting treatment. If you are pregnant, breastfeeding, or are an older adult, consult your healthcare provider before taking this medication to ensure it is safe for your specific situation.

Uses of Gastobid Tablet

Gastobid Tablet is used to manage functional gastrointestinal disorders, such as irritable bowel syndrome and peptic ulcers. The detailed uses of Gastobid Tablet are as follows:

  • Irritable Bowel Syndrome (IBS): It helps calm overactive gut muscles, reducing painful stomach cramps, bloating, and irregular bowel patterns caused by stress.
  • Peptic ulcer disease: This medicine may be used as an adjunctive treatment to help relieve stomach spasms and discomfort associated with peptic ulcers. It is not a primary treatment for ulcer healing, and your doctor may prescribe other medicines, such as acid-suppressing therapy as the main treatment.
  • Gastrointestinal Spasms: It provides targeted relief from acute, painful contractions of the smooth muscles in the digestive tract.
     

Key Benefits

Gastobid Tablet helps relieve digestive discomfort by relaxing intestinal muscle spasms while also reducing anxiety that may worsen gastrointestinal symptoms. This dual action helps improve comfort and supports better day-to-day digestive health.

  • Relieves Abdominal Pain and Muscle Spasms: By relaxing the smooth muscles of the digestive tract, Gastobid Tablet helps ease stomach cramps, spasms, and abdominal discomfort, promoting a more comfortable digestive process.
  • Helps Manage Anxiety-Related Digestive Symptoms: The calming component helps reduce nervousness and tension that can trigger or aggravate digestive symptoms, supporting overall gastrointestinal comfort.
  • Improves Daily Comfort and Wellbeing: By addressing both the physical and emotional factors contributing to digestive discomfort, Gastobid Tablet helps you return to your normal daily activities with greater ease and an improved quality of life.

Directions for Use

  • Take Gastobid Tablet with or without food as advised by your doctor.
  • It is advised to take Gastobid Tablet twice daily; however, follow your doctor’s recommendation regarding the dosage and duration.
  • Swallow it as a whole with a glass of water.
  • Do not crush or chew it.

How Gastobid Tablet Works

Gastobid Tablet works through a dual-action mechanism that addresses both the physical and neurological aspects of digestive distress. The first active component, isopropamide, functions as an anticholinergic agent. It works by blocking specific chemical receptors in the gut, which prevents the nervous system from sending spasm-inducing signals to your digestive muscles. This relaxes the stomach and intestinal walls, helping to relieve painful cramping. It also has a modest effect on reducing stomach acid secretion, although this is not its primary therapeutic role. For peptic ulcer disease, modern treatment primarily relies on proton pump inhibitors (PPIs) or H2-receptor blockers, with this combination serving only as supportive therapy where appropriate. The second active component, trifluoperazine, is a phenothiazine antipsychotic that is used at low doses for its anxiolytic properties in certain gastrointestinal disorders. It acts on the central nervous system to help reduce anxiety and emotional tension that can aggravate digestive symptoms. Because phenothiazines can cause extrapyramidal side effects, such as muscle stiffness, tremors, or involuntary movements, any new neurological symptoms should be reported to your doctor promptly.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Gastobid Tablet as it may worsen sleepiness.

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Pregnancy

Unsafe

Consult your doctor before taking Gastobid Tablet if you are pregnant or planning for pregnancy as Gastobid Tablet may cause harmful effects on the unborn baby.

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Breast Feeding

Unsafe

Breastfeeding is not recommended. Gastobid Tablet may pass into the breast milk and may harm the new-born baby. Breast-feeding mothers should not take Gastobid Tablet.

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Driving

Unsafe

Gastobid Tablet may cause drowsiness and sleepiness. Do not drive or handle machinery unless you are alert.

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Liver

Caution

Gastobid Tablet to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor. However, Gastobid Tablet is not safe in patients with liver disease as per available data.

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Kidney

Caution

Gastobid Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Gastobid Tablet should not be given to children below 6 years of age.

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Heart

Unsafe

Gastobid Tablet is not recommended in cardiac patients due to its adverse effects. However, if prescribed, extreme caution should be exercised.

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Geriatrics

Caution

Gastobid Tablet should be used under caution in geriatric patients. Please consult your physician.

What if I have taken an overdose of Gastobid Tablet

In case of an accidental overdose, seek immediate medical attention. Symptoms of an overdose can include severe dry mouth, extreme drowsiness, rapid heart rate, dilated pupils, fever, or confusion.

Diet & Lifestyle Advise

  • Eat smaller, regular meals: Consuming smaller portions throughout the day prevents your stomach from stretching too much, which reduces the chance of painful spasms.
  • Identify your trigger foods: Keep a detailed food diary to track and avoid foods that provoke your symptoms, such as highly spicy foods, high-fat dishes, caffeine, or alcohol.
  • Stay adequately hydrated: Drink plenty of water throughout the day to help manage dry mouth and reduce the risk of constipation.
  • Manage daily stress: Since anxiety can worsen gut spasms, incorporate stress-relief practices into your routine, such as deep breathing, gentle stretching, or meditation.
  • Introduce fibre carefully: If your symptoms involve changes in bowel habits, add dietary fibre slowly to avoid sudden bloating or gas.
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How Soon It Starts Working

The time required for Gastobid Tablet to start to work: The effect of Gastobid Tablet starts to show its action within 1 to 2 hours of administration. The time for which the effects of Gastobid Tablet last: Gastobid Tablet effect lasts for 6 to 8 hours.

What if you forget to take Gastobid Tablet

If you miss a dose of Gastobid Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Storage

•it is generally stored between 20°C and 25°C (68°F to 77°F). •Keep the medication in its original container, tightly closed, to protect it from moisture and direct light.

Drug Warnings

  • Be careful in hot weather: This medicine can decrease your body's ability to sweat, which makes you more vulnerable to heatstroke. Avoid prolonged exposure to high temperatures and intense physical activity in the heat.
  • Do not drive immediately: Because this medicine can cause blurred vision and drowsiness, do not drive, use tools, or operate heavy machinery until you are certain you can perform these activities safely.
  • Avoid sudden movements: Stand up slowly from a sitting or lying position to prevent a sudden drop in blood pressure, which can make you feel dizzy or lightheaded.
  • Watch for involuntary movements: Alert your doctor immediately if you notice any unusual, uncontrollable movements of your tongue, mouth, face, arms, or legs.
  • Relieve dry mouth safely: Use sugar-free gum, hard candy, or ice chips to stimulate saliva flow if your mouth feels uncomfortably dry.
  • Do not stop treatment suddenly: Because this medicine contains trifluoperazine (a phenothiazine), treatment should only be stopped under medical supervision. Abrupt discontinuation may increase the risk of withdrawal symptoms or neurological effects in some patients.
  • Important note: This combination contains trifluoperazine, which is used at very low doses in this product to help manage anxiety-related gastrointestinal symptoms. Its use for gastrointestinal disorders is considered off-label or legacy practice in many current treatment guidelines, so it should only be used under the guidance of your doctor, who will determine whether it is appropriate for your condition.

Drug-Drug Interactions

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  • Medicines that cause drowsiness (e.g., sleeping pills, opioid pain relievers, muscle relaxants, or antihistamines): Taking Gastobid Tablet together with other central nervous system (CNS) depressants may cause excessive drowsiness, dizziness, impaired coordination, slowed breathing, and, in severe cases, life-threatening respiratory depression. Your doctor may recommend avoiding these combinations or monitoring you closely.
  • Other anticholinergic medicines: Taking Gastobid Tablet with other medicines that have anticholinergic effects may increase the risk of severe dry mouth, constipation, blurred vision, and difficulty passing urine (urinary retention). Inform your doctor if you are taking medicines for allergies, depression, bladder problems, or Parkinson's disease.
  • Oral medicines: Because Gastobid Tablet can slow the movement of food and medicines through the digestive tract, it may delay or reduce the absorption of certain oral medications. Your doctor or pharmacist may advise spacing the timing of your medicines if necessary.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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  • Alcohol: Avoid drinking alcohol while taking Gastobid Tablet, as it can significantly increase drowsiness, dizziness, impaired coordination, and the risk of low blood pressure and falls.
  • Caffeine: Excessive caffeine intake may reduce the calming effects of Gastobid Tablet on the nervous system and digestive tract. Consider limiting coffee, tea, energy drinks, and other caffeinated beverages during treatment.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTICHOLINERGICS]

FAQs

Gastobid Tablet is used to treat irritable bowel syndrome, peptic ulcers, and indigestion.
Gastobid Tablet is a combination of two medicines namely Trifluoperazine and Isopropamide. Isopropamide works by relaxes the muscles in the digestive tract and decreases intestinal spasms. Trifluoperazine is an antipsychotic that works by blocking a chemical messenger's action in the brain known as dopamine that disturbs mood and thoughts.
Constipation might be a side-effect of Gastobid Tablet. Drink enough fluids and eat fiber-rich food if you experience constipation.
Dry mouth could be a side-effect of Gastobid Tablet. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.
Please do not stop taking Gastobid Tablet on your own as it might cause withdrawal symptoms such as fits, shaking, muscle cramps, stomach cramps, depression, vomiting, sleeping problems, and sweating. Consult your doctor if you experience any difficulty while taking Gastobid Tablet, the doctor may gradually reduce the dose.
The most common side effects of Gastobid Tablet are nausea, dryness in the mouth, constipation, sleepiness, weight gain, dizziness, orthostatic hypotension (sudden lowering of blood pressure on standing), difficulty in urination, blurred vision. Most of these side effects of Gastobid Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Yes, you can take Gastobid Tablet after meals. Taking it with food may help reduce any potential stomach discomfort. However, it is recommended that you take it at the same time every day to maintain a consistent level of the medication in your body.
No, you should avoid alcohol while taking Gastobid Tablet. Alcohol can significantly increase the risk of severe drowsiness, dizziness, and dangerous breathing complications. Talk to your doctor if you have concerns about alcohol use.
You should avoid taking Gastobid Tablet during pregnancy unless your doctor decides it is absolutely necessary. Some components of this medicine may affect the developing baby or cause withdrawal symptoms in newborns. Talk to your doctor to discuss safer alternatives.
Yes, Gastobid Tablet can cause drowsiness, tiredness, or blurred vision. You should avoid driving, operating machinery, or performing dangerous tasks until you are sure how this medication affects you. Talk to your doctor if drowsiness persists.
While Gastobid Tablet can help reduce stomach acid production and muscle spasms, it is not a primary treatment for gastro-oesophageal reflux disease (GERD). It is typically prescribed for irritable bowel syndrome or peptic ulcers. Talk to your doctor to find the most appropriate treatment for your acid reflux.

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Country of origin

India

Manufacturer/Marketer address

606,Bansidhar Complex, Opp Polo Ground, Raj Mehal Road, Vadodara-3090001 (Gujarat) INDIA
Other Info - GA40180
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