Gem-Rtu 200Mg/5.26Ml Inj
MRP ₹2343.5
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About Gem-Rtu 200Mg/5.26Ml Inj
Gem-Rtu 200Mg/5.26Ml Inj belongs to the group of anti-cancer drugs called cytotoxics used alone or in combination with other anti-cancer drugs to treat various types of cancers like breast cancer, pancreatic cancer, non-small cell lung cancer, bladder cancer, and ovarian cancer. Cancer is the uninhibited and uncontrolled growth of cells in the body.
Gem-Rtu 200Mg/5.26Ml Inj contains Gemcitabine which works by interfering with the synthesis of DNA, thereby causing cell death and arresting the uncontrolled production of new cells. Thus, Gem-Rtu 200Mg/5.26Ml Inj is very effective in controlling cancer cells from multiplying and is used in the treatment of various types of cancers.
A healthcare professional will administer Gem-Rtu 200Mg/5.26Ml Inj. Do not self-administer. Gem-Rtu 200Mg/5.26Ml Inj may cause certain common side effects such as nausea, hair loss, skin rash, vomiting, and oedema. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist.
It is advisable to inform the doctor if you are allergic to any of the components. Consult your doctor if you are pregnant, planning to get pregnant, or breastfeeding. Talk to your doctor if you are planning to father a child before taking Gem-Rtu 200Mg/5.26Ml Inj; your doctor may advise you regarding sperm storage. Avoid taking alcohol with Gem-Rtu 200Mg/5.26Ml Inj.
Uses of Gem-Rtu 200Mg/5.26Ml Inj
Gem-Rtu 200Mg/5.26Ml Inj is used in the treatment of Breast Cancer, Pancreatic Cancer, Non-small-cell Lung Cancer, Bladder Cancer, and Ovarian Cancer. The detailed use of Gem-Rtu 200Mg/5.26Ml Inj is as follows:
- Treatment of cancer: Gem-Rtu 200Mg/5.26Ml Inj is used to treat several types of solid tumors like pancreatic cancer, non-small cell lung cancer, breast cancer, ovarian cancer, urinary bladder cancer.
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Directions for Use
- Your doctor will decide the dosage and timing of Gem-Rtu 200Mg/5.26Ml Inj based on the type of cancer and your body's response to the treatment.
- Gem-Rtu 200Mg/5.26Ml Inj will be administered by the doctor or nurse in a medical setting.
- Do not self-administer it.
Medicinal Benefits
Gem-Rtu 200Mg/5.26Ml Inj is an anti-cancer drug used in the treatment of various types of cancers. Gem-Rtu 200Mg/5.26Ml Inj is used either independently or in conjunction with other chemotherapy medications to treat breast cancer, pancreatic cancer, non-small cell lung cancer, bladder cancer, and ovarian cancer. Gem-Rtu 200Mg/5.26Ml Inj works by interfering with DNA synthesis. It blocks the production of new DNA, by locking itself into the DNA strands and inhibiting any further proliferation or growth of the cell. Hence, Gem-Rtu 200Mg/5.26Ml Inj has widespread application in the field of oncology (cancer-related medicine) and chemotherapy.
How Gem-Rtu 200Mg/5.26Ml Inj Works
Storage
- Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
- Divide your daily food intake into smaller, more frequent meals to reduce nausea.
- Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
- Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
- Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
- Use ginger (tea, ale, or candies) to help relieve nausea.
- Get adequate rest and also avoid strenuous activities that can worsen nausea.
- Talk to your doctor about taking anti-nausea medication if your nausea is severe.
- Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
- Preventing Vomiting (Before it Happens)
- Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
- Having a small meal before taking your medication can help reduce nausea and vomiting.
- Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
- Managing Vomiting (If it Happens)
- Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
- What to Do if Vomiting Persists
- Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
- Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
- Consume vitamin C-rich foods as they aid iron absorption.
- Limit tea, cocoa, and coffee as these can slow iron absorption.
- Exercise regularly; however, do not overdo it.
- Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
- Avoid contact with people who are sick.
- Wash your hands regularly with soap and water.
- Avoid unpasteurized dairy products.
- Your doctor may recommend regular liver function tests (LFT) to monitor liver enzyme levels.
- To support your liver, eat a healthy diet with lots of fruits, vegetables, lean proteins, and healthy fats.
- Avoid eating processed meats, sugary foods, and unhealthy fats.
- Limit your alcohol consumption, since too much can worsen liver function and contribute to high levels of Alkaline Phosphatase (ALP).
- Stay active with regular exercise, drink plenty of water, and try to avoid harmful chemicals that can damage your liver.
- Quit smoking to lower the risk of elevated ALP levels.
- Increased protein levels indicate the body is dehydrated and when blood plasma is concentrated.
- Consume water and stay hydrated. Talk to your doctor and take an oral rehydrating salt (ORS).
- Sleep for 7-8 hours per night to assist your body in repairing and rebuilding hydration.
- Manage your blood pressure by implementing changes in lifestyle like losing weight, reducing stress and exercising regularly.
- Inform your doctor immediately if you experience a fever after starting a new medication.
- Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
- Monitor your body temperature to monitor fever progression.
- Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
- Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
- Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
- If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
What if I have taken an overdose of Gem-Rtu 200Mg/5.26Ml Inj
Drug Warnings
Gem-Rtu 200Mg/5.26Ml Inj should not be used in case of any known allergy to any of the components. Gem-Rtu 200Mg/5.26Ml Inj should be used with caution in case of high risk or previous history of heart disease, vascular disease, liver problems, kidney disease or alcoholism. Keep your doctor informed if you suffer from any shortness of breath, kidney problems, hypertension diabetes or epilepsy. Avoid Gem-Rtu 200Mg/5.26Ml Inj during pregnancy and breastfeeding. Offer a detailed medical history, vaccination history, and inform the doctor especially if you are on any radiotherapy.
Drug-Drug Interactions
Drug-Drug Interactions
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Gem-Rtu 200Mg/5.26Ml Inj can cause higher levels of Deferiprone in the blood by reducing its excretion rate. This can increase the risk or severity of side effects.
How to manage the interaction:
Although there is a possible interaction between Gem-Rtu 200Mg/5.26Ml Inj and Deferiprone, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, or pain while urinating contact a doctor right away. Do not stop using any medications without a doctor's advice.
When Gem-Rtu 200Mg/5.26Ml Inj is taken with Voclosporin, the amount of Gem-Rtu 200Mg/5.26Ml Inj in the blood can go up. This can increase the risk or severity of side effects.
How to manage the interaction:
There may be a possibility of interaction between Gem-Rtu 200Mg/5.26Ml Inj and Voclosporin, but it can be taken if prescribed by a doctor. If you have any of these symptoms fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain, or burning during urination contact a doctor right away. Do not stop using any medications without talking to a doctor.
Combining Gem-Rtu 200Mg/5.26Ml Inj with Certolizumab can increase the risk of infections.
How to manage the interaction:
Co-administration of Gem-Rtu 200Mg/5.26Ml Inj with Certolizumab can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain, or burning during urination. Do not discontinue any medications without consulting a doctor.
Taking thalidomide together with Gem-Rtu 200Mg/5.26Ml Inj may increase the risk of blood clots and other complications.
How to manage the interaction:
Although taking thalidomide and Gem-Rtu 200Mg/5.26Ml Inj together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
Coadministration of Ketoconazole and Gem-Rtu 200Mg/5.26Ml Inj may increase the risk of liver damage.
How to manage the interaction:
Although taking Ketoconazole and Gem-Rtu 200Mg/5.26Ml Inj together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience a fever, chills, joint pain or swelling, unusual bleeding or bruises, skin rash, itching, tiredness, nausea, vomiting, abdominal pain, dark urine, light stools, or yellowing of the skin or eyes, consult a doctor. Do not discontinue any medication without consulting a doctor.
Combining Gem-Rtu 200Mg/5.26Ml Inj with Natalizumab can increase the risk of side effects.
How to manage the interaction:
Co-administration of Gem-Rtu 200Mg/5.26Ml Inj with Natalizumab can result in an interaction, but it can be taken if your doctor has advised it. If you experience any symptoms such as fever, diarrhea, sore throat, muscle aches, or vision changes, contact a doctor right away. Do not discontinue any medications without consulting a doctor.
Taking Cladribine with Gem-Rtu 200Mg/5.26Ml Inj can increase the risk and severity of developing serious infections.
How to manage the interaction:
Co-administration of Gem-Rtu 200Mg/5.26Ml Inj with Cladribine can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning urination, contact a doctor immediately. Do not stop using any medications without a doctor's advice.
Coadministration of Tofacitinib and Gem-Rtu 200Mg/5.26Ml Inj can lead to or increase the risk of infection.
How to manage the interaction:
There may be a possibility of interaction between Tofacitinib and Gem-Rtu 200Mg/5.26Ml Inj, but it can be taken if advised by a doctor. Contact your doctor immediately if you develop symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting a doctor.
When Gem-Rtu 200Mg/5.26Ml Inj is taken with Lomitapide, the amount of Gem-Rtu 200Mg/5.26Ml Inj in the blood can go up. This can increase the risk or severity of liver injury.
How to manage the interaction:
Co-administration of Gem-Rtu 200Mg/5.26Ml Inj with Lomitapide can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms - liver problems, fever, joint pain, swelling, rash, itching, loss of appetite, tiredness, nausea, vomiting, stomach pain, dark urine, or bleeding please call a doctor right away. Do not stop using any medications without talking to a doctor.
Coadministration of Gem-Rtu 200Mg/5.26Ml Inj with Mipomersen can lead to or increase the risk of liver injury.
How to manage the interaction:
Taking Gem-Rtu 200Mg/5.26Ml Inj with Mipomersen together can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, or bleeding contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Drug-Food Interactions
Drug-Food Interactions
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Diet & Lifestyle Advise
- Cancer can take a toll on anyone. Make sure you regularly see a therapist and take care of your mental health.
- Meditation and yoga have also proven very effective in helping cancer patients maintain a healthy attitude and body.
- Eat more lean meats, healthy fats, fruits, vegetables and whole-grain foods to give you more energy.
- Avoid taking Gem-Rtu 200Mg/5.26Ml Inj with alcohol as there may be an interaction.
- Stay hydrated by drinking plenty of water, as dehydration is often seen in cancers.
- Taking a stroll in the garden or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired.
- Avoid tobacco use.
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Alcohol
Unsafe
It is not recommended to use alcohol with Gem-Rtu 200Mg/5.26Ml Inj as it might lead to increased drowsiness.
Pregnancy
Unsafe
Gem-Rtu 200Mg/5.26Ml Inj should be avoided during pregnancy. Please consult your doctor if you have any concerns.
Breast Feeding
Unsafe
Gem-Rtu 200Mg/5.26Ml Inj is not recommended during breastfeeding. Please consult your doctor in case of any concerns.
Driving
Caution
Gem-Rtu 200Mg/5.26Ml Inj may cause drowsiness and sleepiness, which may affect your ability to drive. Do not drive if you experience any side effects after using Gem-Rtu 200Mg/5.26Ml Inj.
Liver
Caution
Exercise caution before using Gem-Rtu 200Mg/5.26Ml Inj in case of established liver disease. Please consult your doctor to address any concerns.
Kidney
Caution
Exercise caution before using Gem-Rtu 200Mg/5.26Ml Inj in case of established kidney disease. Please consult your doctor to address any concerns.
Children
Unsafe
Gem-Rtu 200Mg/5.26Ml Inj is not recommended for use in children under 18 years of age. Please consult your doctor in case of any concerns.
Heart
Gem-Rtu 200Mg/5.26Ml Inj should be administered with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems before receiving Gem-Rtu 200Mg/5.26Ml Inj.
Geriatrics
Caution
Gem-Rtu 200Mg/5.26Ml Inj should be administered with caution in elderly patients due to an increased risk of side effects. Seek medical advice if you have any concerns.
FAQs
Gem-Rtu 200Mg/5.26Ml Inj belongs to the group of anti-cancer drugs called cytotoxics used alone or in combination with other anti-cancer drugs to treat various types of cancers like breast cancer, pancreatic cancer, non-small cell lung cancer, bladder cancer, and ovarian cancer.
Gem-Rtu 200Mg/5.26Ml Inj works blocking DNA synthesis and causing cell death, thereby preventing the cells from proliferating beyond normal.
Men taking Gem-Rtu 200Mg/5.26Ml Inj are advised not to father a child during the treatment with Gem-Rtu 200Mg/5.26Ml Inj and for 6months after the treatment. Consult your doctor before starting Gem-Rtu 200Mg/5.26Ml Inj if you are planning to father a child. Your doctor may advise you regarding sperm storage.
If you suffer from CKD, please consult with your doctor before using Gem-Rtu 200Mg/5.26Ml Inj and discuss any concerns with them. Gem-Rtu 200Mg/5.26Ml Inj is to be used with caution in those suffering from kidney and liver problems.
Gem-Rtu 200Mg/5.26Ml Inj might cause low white blood cell count leading to increased risk of infections. Consult your doctor if you have a fever, sweating, and any signs of infections.
Gem-Rtu 200Mg/5.26Ml Inj may cause bleeding and bruising due to less platelet count. Consult a doctor if you notice unexpected bruising, pinkish or reddish urine, bleeding from gums, mouth, or nose.
Gem-Rtu 200Mg/5.26Ml Inj contains Gemcitabine which works by interfering with the synthesis of DNA, thereby causing cell death and arresting the uncontrolled production of new cells. It is very effective in controlling cancer cells from multiplying and is used for the treatment of various types of cancers.
The side effects of Gem-Rtu 200Mg/5.26Ml Inj include hair loss, vomiting, nausea, skin rash and oedema. Consult the doctor if any of these symptoms persist or worsen.
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Reference
- https://www.medicines.org.uk/emc/files/pil.2839.pdf
- https://chemocare.com/chemotherapy/drug-info/gemcitabine.aspx
- https://pubmed.ncbi.nlm.nih.gov/7481842/
- https://www.cancer.gov/about-cancer/understanding/what-is-cancer
- https://www.webmd.com/drugs/2/drug-13451/gemcitabine-intravenous/details
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649805/
