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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Gentastar 40 mg Injection 2 ml is an antibiotic used in the treatment of bacterial infections of the ear, nose, throat, respiratory tract, gastrointestinal tract, biliary tract, bone and joint, skin and soft tissue. It helps by inhibiting the protein synthesis of the bacterial cell and thereby helps fight infection causing bacteria. This medicine is not effective for treating viral infections.
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Composition :

GENTAMICIN-40MG

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Gentastar 40 mg Injection 2 ml

Gentastar 40 mg Injection 2 ml belongs to the class of 'antibiotics', primarily used to treat serious bacterial infections. Bacterial infection occurs when harmful bacteria grow in the body and causes illness. It can infect any part of the body and multiply very quickly. 

Gentastar 40 mg Injection 2 ml is composed of Gentamicin, an aminoglycoside antibiotic. It prevents bacteria from synthesising essential proteins required to carry out vital functions. It has broad-spectrum activity against aerobic gram-positive and gram-negative bacteria. 

Gentastar 40 mg Injection 2 ml will be administered by a healthcare professional. Gentastar 40 mg Injection 2 ml may cause a few side effects, although not everybody gets them. Common side effects of Gentastar 40 mg Injection 2 ml include stomach upset, nausea, vomiting, loss of appetite, weight loss, light-headedness, headache, mood changes, joint pain, itching or rash, pain and swelling at the injection site. Most of these side effects do not require medical attention and gradually resolve over time. If these side effects persist longer, please consult your doctor.

Let your doctor know if you have any allergic reactions to medicines, liver/kidney problems, cystic fibrosis (a genetic disorder that affects the digestive and respiratory system), hearing problems, electrolyte imbalance, myasthenia gravis (muscular weakness), or Parkinson's disease before starting Gentastar 40 mg Injection 2 ml. Gentastar 40 mg Injection 2 ml should be used only with a doctor's advice during pregnancy and breastfeeding. Gentastar 40 mg Injection 2 ml may cause light-headedness; in such cases, please do not drive until you are alert. Gentastar 40 mg Injection 2 ml may cause dizziness/vertigo; hence avoid or limit alcohol consumption. 

Uses of Gentastar 40 mg Injection 2 ml

Treatment of Bacterial infections

Directions for Use

Gentastar 40 mg Injection 2 ml will be administered by a healthcare professional. Do not self-administer.

Medicinal Benefits

Gentastar 40 mg Injection 2 ml is an antibiotic that treats severe/serious bacterial infections. It contains Gentamicin which works by inhibiting bacterial protein synthesis, thus inhibiting bacterial growth. It shows a bacteriostatic effect, which stops bacterial reproduction but doesn't kill them. Gentastar 40 mg Injection 2 ml is useful in treating recurrent infections of kidneys, urinary ducts and bladder, lungs and airways infections during hospitalization, infections of the skin and soft tissues, including burns, and sepsis (blood poisoning by bacteria).

How Gentastar 40 mg Injection 2 ml Works

Gentastar 40 mg Injection 2 ml is composed of Gentamicin, an aminoglycoside antibiotic. It prevents bacteria from synthesising essential proteins required to carry out vital functions. It has broad-spectrum activity against aerobic gram-positive and gram-negative bacteria.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Gentastar 40 mg Injection 2 ml

Gentastar 40 mg Injection 2 ml is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. An accidental overdose may cause kidney damage, renal failure and nerve damage. Your doctor may take necessary measures if an overdose is suspected.

Drug Warnings

Brief your medical history to the doctor if you are allergic to any of the components in Gentastar 40 mg Injection 2 ml. Let your doctor know if you have any liver/kidney problems, cystic fibrosis, hearing problems, low blood minerals, myasthenia gravis, or Parkinson's disease. Inform your doctor if you are pregnant or breastfeeding before starting this medicine. Gentastar 40 mg Injection 2 ml may cause dizziness; hence drive or operate machinery only when you are alert. Avoid alcohol consumption to prevent any undesired effects like dizziness while undergoing treatment. 

Drug-Drug Interactions

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GentamicinMannitol
Severe

Drug-Drug Interactions

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How does the drug interact with Gentastar 40 mg Injection 2 ml:
Co-administration of Gentastar 40 mg Injection 2 ml and Temsirolimus may increase the risk of kidney problems.

How to manage the interaction:
Co-administration of Gentastar 40 mg Injection 2 ml with Temsirolimus can possibly result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on how much you pee. If you notice any changes like peeing more or less than usual, it's a good idea to let your doctor know right away. Some signs to watch out for include gaining weight quickly, feeling bloated, having trouble breathing, or feeling sick to your stomach. Other symptoms to be aware of are not feeling hungry, losing weight, swelling, muscle cramps, feeling weak or dizzy, feeling confused, or having an irregular heartbeat. Do not stop using any medications without a doctor's advice.
GentamicinMannitol
Severe
How does the drug interact with Gentastar 40 mg Injection 2 ml:
Co-administration of Mannitol with Gentastar 40 mg Injection 2 ml can increase the risk of kidney damage.

How to manage the interaction:
There may be a possibility of interaction between Gentastar 40 mg Injection 2 ml and Mannitol, but it can be taken if prescribed by a doctor. If you're having problems like hearing loss, ringing in your ears, feeling dizzy, or having kidney issues, it's important to let your doctor know right away. They may be able to recommend other options for you that won't cause these problems. Do not stop using any medications without a doctor's advice.
How does the drug interact with Gentastar 40 mg Injection 2 ml:
Coadministration of Sirolimus with Gentastar 40 mg Injection 2 ml may increase the risk or severity of kidney problems.

How to manage the interaction:
Although there is a possible interaction, Gentastar 40 mg Injection 2 ml can be taken with sirolimus if prescribed by the doctor. Consult the doctor if you experience symptoms of kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medication without consulting your doctor.
How does the drug interact with Gentastar 40 mg Injection 2 ml:
Taking Gentastar 40 mg Injection 2 ml with cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Although taking Gentastar 40 mg Injection 2 ml and cidofovir together can possibly cause an interaction, it can be taken if your doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Gentastar 40 mg Injection 2 ml:
When Rocuronium is used with Gentastar 40 mg Injection 2 ml, it can make the treatment more effective.

How to manage the interaction:
Co-administration of Rocuronium bromide with Gentastar 40 mg Injection 2 ml can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
GentamicinMetrizamide
Severe
How does the drug interact with Gentastar 40 mg Injection 2 ml:
Co-administration of Metrizamide with Gentastar 40 mg Injection 2 ml may increase the risk of kidney problems.

How to manage the interaction:
Taking Gentastar 40 mg Injection 2 ml with Metrizamide together can possibly result in an interaction, but it can be taken if your doctor has advised it. It's important to keep an eye on how much you pee. If you notice any changes, like peeing more or less than usual, it's a good idea to let a doctor know right away. Other symptoms to watch out for include feeling sick, throwing up, not wanting to eat, gaining or losing weight suddenly, or having trouble with your muscles, balance, or heart rhythm. Do not stop using any medications without a doctor's advice.
How does the drug interact with Gentastar 40 mg Injection 2 ml:
Co-administration of Tenofovir alafenamide may cause kidney problems and combining it Gentastar 40 mg Injection 2 ml may increase that risk.

How to manage the interaction:
Although there is a possible interaction, Gentastar 40 mg Injection 2 ml can be taken with tenofovir alafenamide if prescribed by the doctor. Consult the doctor if you experience signs and symptoms of kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without consulting a doctor.
GentamicinFoscarnet
Severe
How does the drug interact with Gentastar 40 mg Injection 2 ml:
Co-administration of Gentastar 40 mg Injection 2 ml with Foscarnet can increase the risk of kidney damage.

How to manage the interaction:
Although taking Gentastar 40 mg Injection 2 ml and Foscarnet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms, it's important to contact your doctor right away: seizures, an irregular heart rhythm, feeling sick, swelling, sudden weight gain or loss, severe pain in your upper stomach, strong heartbeats, feeling dizzy, or chest pain. Do not stop using any medications without a doctor's advice.
How does the drug interact with Gentastar 40 mg Injection 2 ml:
Co-administration of Human immunoglobulin with Gentastar 40 mg Injection 2 ml may raise the risk of kidney problems.

How to manage the interaction:
Although taking Human immunoglobulin and Gentastar 40 mg Injection 2 ml together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
GentamicinIopamidol
Severe
How does the drug interact with Gentastar 40 mg Injection 2 ml:
Co-administration of Iopamidol with Gentastar 40 mg Injection 2 ml may increase the risk of kidney problems.

How to manage the interaction:
Co-administration of Gentastar 40 mg Injection 2 ml with Iopamidol can possibly result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on how much you pee. If you notice any changes, like peeing more or less than usual, it's a good idea to let your doctor know right away. These changes could be a sign of problems with your kidneys, diabetes, or other health issues. Other symptoms to watch out for include feeling sick, throwing up, not wanting to eat, gaining or losing weight suddenly, or having trouble breathing. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Wash your hands often to maintain cleanliness.
  • Include whole-grain foods like multigrain bread and brown rice in your diet. 
  • Taking probiotics after an antibiotic treatment reduces the risk of antibiotic-associated diarrhoea. 
  • Try taking yoghurt, cheese, sauerkraut, and kimchi that help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet that is easily digested by your gut bacteria. Fibre foods may also help restore healthy gut bacteria after a course of antibiotics. 
  • Avoid intake of alcoholic beverages as it can make you dehydrated and affect your sleep. 
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep. 

Habit Forming

No

Therapeutic Class

ANTIBIOTICS
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Alcohol

Caution

Limit or avoid alcohol intake while being treated with Gentastar 40 mg Injection 2 ml since it may worsen side effects like dizziness.

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Pregnancy

Caution

Gentastar 40 mg Injection 2 ml should be cautiously administered during pregnancy since there are chances of fetal harm. Please consult your doctor before taking Gentastar 40 mg Injection 2 ml if you are pregnant or planning to conceive.

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Breast Feeding

Caution

Gentastar 40 mg Injection 2 ml can be excreted into breast milk in small amounts when used by a nursing mother. Please consult your doctor before taking Gentastar 40 mg Injection 2 ml if you are breastfeeding.

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Driving

Caution

Gentastar 40 mg Injection 2 ml may cause side effects like dizziness or vertigo that could affect your driving ability. Do not drive or operate machinery in such cases. Drive only when you are mentally alert.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Gentastar 40 mg Injection 2 ml since it may cause abnormal liver function tests.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases or impairment before taking Gentastar 40 mg Injection 2 ml. Dose adjustment may be required.

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Children

Caution

Gentastar 40 mg Injection 2 ml should be used for children only when prescribed by a doctor. The dose may depend on the child's age and body weight.

Have a query?

FAQs

Gentastar 40 mg Injection 2 ml belongs to the class of 'antibiotics', primarily used to treat serious bacterial infections. Bacterial infection occurs when harmful bacteria grow in the body and causes illness.

Gentastar 40 mg Injection 2 ml is an antibiotic that treats bacterial infections. It works by inhibiting bacterial protein synthesis, which retards bacterial growth.

Gentastar 40 mg Injection 2 ml should be used with proper caution and doctor consultation if you have any allergic reactions to medicines, liver/kidney problems, cystic fibrosis, hearing problems, low blood minerals/electrolyte imbalance, myasthenia gravis (muscular weakness), and Parkinson's disease.

Gentastar 40 mg Injection 2 ml can affect the live vaccines like typhoid vaccine and decrease its effectiveness. Please consult a doctor if you are undergoing any vaccinations.

Gentastar 40 mg Injection 2 ml may cause abnormal liver function tests as one of its side effects. It may increase the levels of liver enzymes and blood bilirubin. Please consult your doctor before starting Gentastar 40 mg Injection 2 ml if you have any history of liver problems.

Diarrhoea can be a side-effect of Gentastar 40 mg Injection 2 ml. Clostridium difficile-associated diarrhoea (CDAD) is also reported during usage of antibiotics like Gentastar 40 mg Injection 2 ml. Therefore, when the patient has diarrhoea, undergoing an examination is advised to rule out the chances of CDAD following Gentastar 40 mg Injection 2 ml therapy.

Country of origin

India

Manufacturer/Marketer address

G-54 3Rd Floor Laxmi Nagar Vikas Marg Delhi -110092
Other Info - GEN0518

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