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  3. Gestobond 400 Softgel Capsule 10's

Gestobond 400 Softgel Capsule 10's, Pack of 10
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

Gestobond 400 Softgel Capsule 10's is a female hormone used in the treatment of female infertility. This medicine helps boost the production of hormones involved in the ovulation process. Common side effects include flushing (reddening of the skin, especially the face), headache, Insomnia, tiredness, dizziness, breast pain or tenderness, heavy periods, etc. It is also used to restore the menstrual cycle in women who have missed their periods. This medicine is only intended for use in women. Hence should not be used in male population, pregnant/breastfeeding women, and children.

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Composition :

PROGESTERONE-400MG

Manufacturer/Marketer :

Gufic Bioscience Ltd

Consume Type :

VAGINAL

Return Policy :

Not Returnable

Expires on or after :

About Gestobond 400 Softgel Capsule 10's

Gestobond 400 Softgel Capsule 10's is used to treat female infertility and to aid pregnancy. Female infertility is a condition in which a female body is unable to conceive despite regular, unprotected sexual intercourse for at least one year.

Gestobond 400 Softgel Capsule 10's contains progesterone, a female hormone that regulates ovulation and menstruation in women. 

In some cases, Gestobond 400 Softgel Capsule 10's may cause abdominal pain, headache, constipation, nausea, and breast pain/enlargement. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Use Gestobond 400 Softgel Capsule 10's as directed by your doctor. It is intended for intra-vaginal use only. Wash your hands thoroughly with soap and water before and after each use. Ensure the vaginal area is clean and dry before applying the medicament.

Inform your doctor if you are allergic to it. Before using Gestobond 400 Softgel Capsule 10's inform your doctor if you have/had liver or kidney problems, heart problems, diabetes, asthma, epilepsy, migraine or depression. Let your doctor know if you are pregnant or breastfeeding. Avoid smoking and alcohol consumption as it can worsen the condition.

Uses of Gestobond 400 Softgel Capsule 10's

Gestobond 400 Softgel Capsule 10's is used in the treatment of female infertility. The detailed uses of Gestobond 400 Softgel Capsule 10's are as follows:<br/>

  • Luteal Phase Support: Gestobond 400 Softgel Capsule 10's is prescribed to support the luteal phase during assisted reproductive technologies like in vitro fertilization (IVF), increasing the chances of pregnancy.<br/>
  • Menstrual Disorders: Gestobond 400 Softgel Capsule 10's helps regulate the menstrual cycle and manage symptoms related to irregular menstruation.<br/>
  • Endometrial Preparation: Gestobond 400 Softgel Capsule 10's aids in preparing the endometrium for implantation during fertility treatments, ensuring an optimal environment for a fertilized egg.<br/>
  • Prevention of Miscarriage: In some cases, Gestobond 400 Softgel Capsule 10's is recommended for pregnant women with a history of recurrent miscarriages to help maintain the pregnancy and provide support during its early stages.<br/>

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication. • Check the label for directions before using Gestobond 400 Softgel Capsule 10's. Gently insert the applicator into the vagina while lying down or standing with one leg raised. Push the plunger to release the medication. • Wash your hands thoroughly with soap and water. Ensure the vaginal area is clean and dry. Remove the applicator carefully and remain lying down for a few minutes to allow the medication to absorb.

Medicinal Benefits

  • Gestobond 400 Softgel Capsule 10's contains progesterone, which helps with ovulation and menstruation.
  • It also causes secretory changes in the uterine endometrium, relaxes the uterus, prevents follicle maturation, and helps maintain pregnancy.
  • It is also used to restore the menstrual cycle in women who have missed their periods.

How Gestobond 400 Softgel Capsule 10's Works

Gestobond 400 Softgel Capsule 10's contains progesterone, a female hormone that regulates ovulation and menstruation in women. Gestobond 400 Softgel Capsule 10's induces secretory changes in the endometrium lining of the uterus, relaxes the uterus, blocks the maturation and release of follicles and maintains pregnancy.

Storage

• Store in a cool and dry place away from sunlight.• Keep Gestobond 400 Softgel Capsule 10's out of sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Gestobond 400 Softgel Capsule
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.

What if I have taken an overdose of Gestobond 400 Softgel Capsule 10's

Avoid exceeding the recommended dose as it might cause an overdose. Consult the doctor if you experience any unusual symptoms.

Drug Warnings

  • Do not use Gestobond 400 Softgel Capsule 10's if you are allergic to any of its components
  • Let your doctor know if you have if you have any history of unexplained vaginal bleeding, porphyria, cancer, thrombophlebitis and missed abortion or miscarriage.
  • Keep your doctor informed about your health condition and all the medicines you are taking before taking Gestobond 400 Softgel Capsule 10's to rule out any side effects/interactions.
  • If you are pregnant, planning for pregnancy or breastfeeding, please consult a doctor before taking Gestobond 400 Softgel Capsule 10's.
  • Gestobond 400 Softgel Capsule 10's is not recommended for children below 18 years of age.
  • Before taking this medication, your doctor will do a smear test and examine your breasts and pelvic area.

Drug-Drug Interactions

verifiedApollotooltip
ProgesteroneMorphine
Severe
ProgesteroneVenetoclax
Severe

Drug-Drug Interactions

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ProgesteroneMorphine
Severe
How does the drug interact with Gestobond 400 Softgel Capsule:
Co-administration of Gestobond 400 Softgel Capsule with Morphine may increase the blood levels and side effects of Morphine.

How to manage the interaction:
Co-administration of Morphine with Gestobond 400 Softgel Capsule can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.
ProgesteroneVenetoclax
Severe
How does the drug interact with Gestobond 400 Softgel Capsule:
Co-administration of Gestobond 400 Softgel Capsule with Venetoclax may increase the blood levels of Venetoclax which increases the risk of side effects.

How to manage the interaction:
Although taking Gestobond 400 Softgel Capsule and Venetoclax together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any symptoms such as fatigue, nausea, vomiting, diarrhea, and infections, it is advised to consult a doctor. Without consulting a doctor, never stop taking any drugs.
ProgesteroneEdoxaban
Severe
How does the drug interact with Gestobond 400 Softgel Capsule:
When Gestobond 400 Softgel Capsule is taken with Edoxaban, may increase the blood levels of Edoxaban which increases the risk of serious bleeding complications.

How to manage the interaction:
Although taking Gestobond 400 Softgel Capsule and edoxaban together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness, you should consult a doctor. Do not discontinue any medications without a doctor's advice.
ProgesteroneTirzepatide
Moderate
How does the drug interact with Gestobond 400 Softgel Capsule:
Gestobond 400 Softgel Capsule may interfere with blood glucose control and reduce the effectiveness of tirzepatide and other diabetic medications.

How to manage the interaction:
It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Monitor your blood sugar levels closely.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • It is critical to lose weight and maintain a healthy BMI in order to boost fertility.
  • Caffeine and caffeinated drinks should be avoided for improved fertility.
  • Reduce your carbohydrate intake and eat more antioxidant-rich foods.
  • Include beans, lentils, Greek yoghurt, cheese, probiotics, and vitamin D, as they aid in ovulation.
  • Asparagus should be included in your everyday diet. Asparagus is a superfood that has amazing benefits for women attempting to conceive.
  • Quit smoking.
  • Avoid consumption of alcohol.

Habit Forming

No

Therapeutic Class

HORMONES

Gestobond 400 Softgel Capsule 10's Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

It is not known if alcohol affects Gestobond 400 Softgel Capsule 10's. However, it is advisable not to take or limit alcohol as a precautionary measure.

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Pregnancy

Caution

Contact the doctor before using Gestobond 400 Softgel Capsule 10's. Your doctor will decide whether Gestobond 400 Softgel Capsule 10's should be used by the pregnant woman or not depending on her condition.

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Breast Feeding

Unsafe

The use of Gestobond 400 Softgel Capsule 10's during breastfeeding is not recommended.

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Driving

Caution

Gestobond 400 Softgel Capsule 10's does not influence the ability to drive and use machines.

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Liver

Unsafe

Do not use Gestobond 400 Softgel Capsule 10's if you have/had liver disease or abnormal liver tests.

bannner image

Kidney

Consult your doctor

Please consult your doctor if you have aany kidney disease. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Unsafe

Gestobond 400 Softgel Capsule 10's is not recommended for use in children or adolescents.

Have a query?

FAQs

Gestobond 400 Softgel Capsule 10's belongs to the class of medicines known as hormones used to treat female infertility and to aid pregnancy. It is also used to restore the menstrual cycle in women who have missed their periods.

Gestobond 400 Softgel Capsule 10's causes secretory changes in the uterine endometrium, relaxes the uterus, prevents follicle maturation, and helps to maintain pregnancy.

Do not use Gestobond 400 Softgel Capsule 10's if you are allergic to any of its components or if you have/had porphyria, breast or genital cancer, abnormal vaginal bleeding due to miscarriage or missed abortion, blood clots or stroke, liver disease or abnormal liver tests.

Abnormal uterine bleeding, irregular or missed periods (amenorrhea), abdominal pain during pregnancy and frequent miscarriages are the signs of low progesterone. Additionally, low progesterone levels lead to high estrogen levels, and women can have decreased sex drive, weight gain or gallbladder problems.

Gestobond 400 Softgel Capsule 10's may cause vaginal spotting, vaginal irritation, or application site reactions. Consult your doctor if the condition persists or worsens.

Country of origin

India

Manufacturer/Marketer address

37,1St Floor, Kamala Bhavan Ii, Swami Nityanand Road, Andheri (East), Mumbai - 400 069. (India).
Other Info - GES0139

Disclaimer

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 23, 2025 | 2:12 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.1283.pdf
  2. https://www.medicines.org.uk/emc/product/1283/smpc
  3. https://www.medsafe.govt.nz/Consumers/cmi/c/crinone.pdf
  4. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/020701s026lbl.pdf

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