If you are allergic to soya, PROGESTERONE or any other medicines, please tell your doctor. Avoid taking PROGESTERONE if you have breast cancer, unexplained vaginal bleeding, blood clots or blood clotting disorder, liver disease, porphyria (a disorder in the formation of red blood pigment) or cerebral haemorrhage  (bleeding in the brain). Avoid taking PROGESTERONE if you are pregnant as it may harm the unborn baby. You are advised to use effective birth control methods while taking PROGESTERONE to prevent pregnancy. However, if you are pregnant, planning for pregnancy or breastfeeding, please consult a doctor before taking PROGESTERONE. Drive only if you are alert as PROGESTERONE may cause drowsiness or dizziness. If you have diabetes, high blood pressure, migraine or severe headaches, gallstones, asthma, fits, systemic lupus erythematosus (an autoimmune disease) or if you ever had depression, inform your doctor before taking PROGESTERONE. If you are about to undergo any surgery, please inform your doctor that you are taking PROGESTERONE.

Drug-Drug Interaction: PROGESTERONE may interact with anticonvulsants (carbamazepine, phenytoin, phenobarbital), anti-tuberculosis drugs (rifabutin, rifampicin), anti-HIV drugs (ritonavir, nevirapine, nelfinavir, efavirenz), benzodiazepine (diazepam), water tablet (spironolactone), immunosuppressant (ciclosporin), blood thinners (phenindione), skeletal muscle relaxants (tizanidine), antifungals (terbinafine, ketoconazole, griseofulvin).

Drug- Food Interaction: PROGESTERONE may interact with St. Jonh’s wort (herbal supplement to treat depression).

Drug-Disease Interaction: Avoid taking PROGESTERONE if you have breast cancer, unexplained vaginal bleeding, blood clots or blood clotting disorder, liver disease, porphyria (a disorder in the formation of red blood pigment), or cerebral hemorrhage  (bleeding in the brain). If you have diabetes, high blood pressure, migraine or severe headaches, gallstones, asthma, fits, systemic lupus erythematosus (an autoimmune disease), or if you ever had depression, inform your doctor before taking PROGESTERONE.

• Do regular exercise and physical activity to minimize hot flushes and improve sleep. Aerobics, yoga, and activities like tai chi may help in relaxing the body and mind.
• Try to wear loose clothes before going to bed and sleep in a cool, well-ventilated room. Doing this can prevent symptoms of hot flushes and night sweats. Take minimum sleep of 8 hours.
• Avoid or limit intake of caffeine-containing beverages, alcohol, and spicy food, as these are known triggering agents for hot flushes.
• Try to be stress-free to improve your mood swings due to hormonal fluctuations.
• Quit smoking as it will help to reduce hot flushes and your risk of developing chronic conditions like heart disease, stroke, and cancer.

If you need to undergo any blood test, please inform the lab technician that you are taking hormone replacement therapy (HRT) as it may affect some test results.