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  3. Gestofem-400 Softgel Capsule 10's

Gestofem-400 Softgel Capsule 10's, Pack of 10 SoftgelsS
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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

Gestofem-400 Softgel Capsule is used to treat amenorrhoea (absence of menstrual periods) and prevent endometrial hyperplasia (thickened uterus lining). Also, it is indicated for the maintenance of pregnancy, threatened abortion and prevention of preterm labour. It contains progesterone which works by replacing oestrogen and progesterone hormone levels in the body. This medicine may sometimes cause side effects such as dizziness, drowsiness, headache, mood changes, diarrhoea, vaginal discharge, joint pain, hot flashes or constipation. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Composition :

PROGESTERONE-400MG

Manufacturer/Marketer :

Gynofem Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Gestofem-400 Softgel Capsule

Gestofem-400 Softgel Capsule is used as hormone replacement therapy, and in the treatment of amenorrhoea (absence of menstrual periods), prevents endometrial hyperplasia (thickened uterus lining). Hormone replacement therapy is a treatment to relieve menopause symptoms. It replaces hormones that are at a lower level as you approach menopause.

Gestofem-400 Softgel Capsule contains progesterone, which works by replacing oestrogen and progesterone hormone levels in the body and providing relief from menopause symptoms.

In some cases, you may experience side effects such as dizziness, drowsiness, headache, mood changes, diarrhoea, vaginal discharge, joint pain, or constipation. Most of these side effects do not require medical attention and resolve on their own. However, if they persist, please consult your doctor.

Administer Gestofem-400 Softgel Capsule orally, with or without food. You are advised to take Gestofem-400 Softgel Capsule for as long as your doctor has prescribed it for you based on your medical condition. For better results, take Gestofem-400 Softgel Capsule around the same time daily.

If you are allergic to soy, Gestofem-400 Softgel Capsule , or any other medicines, please tell your doctor. Avoid taking Gestofem-400 Softgel Capsule if you have breast cancer, unexplained vaginal bleeding, blood clots or blood clotting disorder, liver disease, porphyria (a disorder in the formation of red blood pigment) or cerebral haemorrhage (bleeding in the brain). Avoid taking Gestofem-400 Softgel Capsule if you are pregnant, as it may harm the unborn baby. Drive only if you are alert, as Gestofem-400 Softgel Capsule may cause drowsiness or dizziness.

Uses of Gestofem-400 Softgel Capsule

Gestofem-400 Softgel Capsule is used in the treatment of female infertility and female hormonal imbalance. The detailed uses of Gestofem-400 Softgel Capsule are as follows:<br/> 

  • Hormonal Replacement Therapy: Gestofem-400 Softgel Capsule is commonly used in women undergoing hormonal replacement therapy to manage symptoms associated with menopause or hormonal imbalances.<br/>
  • Luteal Phase Support: Gestofem-400 Softgel Capsule is prescribed to support the luteal phase during assisted reproductive technologies like in vitro fertilization (IVF), increasing the chances of pregnancy.<br/>
  • Menstrual Disorders: Gestofem-400 Softgel Capsule helps regulate the menstrual cycle and manage symptoms related to irregular menstruation.<br/>
  • Endometrial Preparation: Gestofem-400 Softgel Capsule aids in preparing the endometrium for implantation during fertility treatments, ensuring an optimal environment for a fertilized egg.<br/>
  • Prevention of Miscarriage: In some cases, Gestofem-400 Softgel Capsule is recommended for pregnant women with a history of recurrent miscarriages to help maintain the pregnancy and provide support during its early stages.<br/>

Directions for Use

• Gestofem-400 Softgel Capsule can be taken with or without food as advised by your doctor. • Follow your doctor's instructions on the dosage and timing of this medication. • Swallow Gestofem-400 Softgel Capsule as a whole with a glass of water. • Do not crush, break, or chew it.

Medicinal Benefits

  • Gestofem-400 Softgel Capsule contains progesterone that is used in combination with oestrogen for hormone replacement therapy.
  • Gestofem-400 Softgel Capsule replaces estrogen and progesterone hormone levels in the body and helps in providing relief from menopause symptoms.
  • Gestofem-400 Softgel Capsule is also indicated for the maintenance of pregnancy, threatened abortion and prevention of preterm labour.

How Gestofem-400 Softgel Capsule Works

Gestofem-400 Softgel Capsule contains progesterone, which works by replacing oestrogen and progesterone hormone levels in the body and providing relief from menopause symptoms.

Storage

• Store in a cool and dry place away from sunlight.• Keep Gestofem-400 Softgel Capsule out of reach and sight of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Gestofem-400 Softgel Capsule
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.

What if I have taken an overdose of Gestofem-400 Softgel Capsule

Avoid exceeding the recommended dose as it might cause an overdose. Seek immediate medical attention if you experience any unusual symptoms.

Drug Warnings

  • If you are allergic to soy, Gestofem-400 Softgel Capsule , or any other medicines, please tell your doctor.
  • Avoid taking Gestofem-400 Softgel Capsule if you have breast cancer, unexplained vaginal bleeding, blood clots or blood clotting disorder, liver disease, porphyria (a disorder in the formation of red blood pigment) or cerebral haemorrhage  (bleeding in the brain).
  • Avoid taking Gestofem-400 Softgel Capsule if you are pregnant, as it may harm the unborn baby.
  • You are advised to use effective birth control methods while taking Gestofem-400 Softgel Capsule to prevent pregnancy.
  • If you are pregnant, planning for pregnancy or breastfeeding, please consult a doctor before taking Gestofem-400 Softgel Capsule .
  • It is advised to drive only if you are alert, as Gestofem-400 Softgel Capsule may cause drowsiness or dizziness.
  • If you have diabetes, high blood pressure, migraine or severe headaches, gallstones, asthma, fits, systemic lupus erythematosus (an autoimmune disease) or if you ever had depression, inform your doctor before taking Gestofem-400 Softgel Capsule .
  • Also, if you are about to undergo any surgery, please inform your doctor that you are taking Gestofem-400 Softgel Capsule .

Drug-Drug Interactions

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ProgesteroneEdoxaban
Severe
ProgesteroneVenetoclax
Severe

Drug-Drug Interactions

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ProgesteroneEdoxaban
Severe
How does the drug interact with Gestofem-400 Softgel Capsule:
When Gestofem-400 Softgel Capsule is taken with Edoxaban, may increase the blood levels of Edoxaban which increases the risk of serious bleeding complications.

How to manage the interaction:
Although taking Gestofem-400 Softgel Capsule and edoxaban together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness, you should consult a doctor. Do not discontinue any medications without a doctor's advice.
ProgesteroneVenetoclax
Severe
How does the drug interact with Gestofem-400 Softgel Capsule:
Co-administration of Gestofem-400 Softgel Capsule with Venetoclax may increase the blood levels of Venetoclax which increases the risk of side effects.

How to manage the interaction:
Although taking Gestofem-400 Softgel Capsule and Venetoclax together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any symptoms such as fatigue, nausea, vomiting, diarrhea, and infections, it is advised to consult a doctor. Without consulting a doctor, never stop taking any drugs.
ProgesteroneMorphine
Severe
How does the drug interact with Gestofem-400 Softgel Capsule:
Co-administration of Gestofem-400 Softgel Capsule with Morphine may increase the blood levels and side effects of Morphine.

How to manage the interaction:
Co-administration of Morphine with Gestofem-400 Softgel Capsule can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.
ProgesteroneTirzepatide
Moderate
How does the drug interact with Gestofem-400 Softgel Capsule:
Gestofem-400 Softgel Capsule may interfere with blood glucose control and reduce the effectiveness of tirzepatide and other diabetic medications.

How to manage the interaction:
It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Monitor your blood sugar levels closely.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do regular exercise and physical activity to minimize hot flushes and improve sleep. Aerobics, yoga, and activities like tai chi may help in relaxing the body and mind.
  • Try to wear loose clothes before going to bed and sleep in a cool, well-ventilated room. Doing this can prevent symptoms of hot flushes and night sweats. Take minimum sleep of 8 hours.
  • Avoid or limit intake of caffeine-containing beverages, alcohol, and spicy food, as these are known triggering agents for hot flushes.
  • Try to be stress-free to improve your mood swings due to hormonal fluctuations.
  • Quit smoking as it will help to reduce hot flushes and your risk of developing chronic conditions like heart disease, stroke, and cancer.

Habit Forming

No

Therapeutic Class

HORMONES

Gestofem-400 Softgel Capsule Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Consult your doctor

Interaction of Gestofem-400 Softgel Capsule with alcohol is unknown. Please consult a doctor before consuming alcohol while using Gestofem-400 Softgel Capsule .

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Pregnancy

Consult your doctor

Gestofem-400 Softgel Capsule supports pregnancy and helps in the maintenance of pregnancy. However, please consult a doctor if you are pregnant before taking Gestofem-400 Softgel Capsule .

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Breast Feeding

Consult your doctor

Gestofem-400 Softgel Capsule may be excreted in human milk. Therefore, please consult a doctor if you are breastfeeding.

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Driving

Unsafe

Gestofem-400 Softgel Capsule may cause dizziness or drowsiness. Therefore, avoid driving if you feel dizzy or drowsy after taking Gestofem-400 Softgel Capsule .

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Liver

Consult your doctor

Please consult a doctor if you have a history of liver disease. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Gestofem-400 Softgel Capsule should be given with caution, especially if you have a history of kidney disease. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Gestofem-400 Softgel Capsule is not recommended for children.

Have a query?

FAQs

Gestofem-400 Softgel Capsule is used in combination with oestrogen for hormone replacement therapy. Besides this, Gestofem-400 Softgel Capsule also treats amenorrhoea (absence of menstrual periods) and prevents endometrial hyperplasia (thickened uterus lining). Also, it is indicated for the maintenance of pregnancy, threatened abortion and prevention of preterm labour.

Gestofem-400 Softgel Capsule contains Progesterone that works by replacing oestrogen and progesterone hormone levels in the body and helps in providing relief from menopause symptoms.

Gestofem-400 Softgel Capsule may increase the risk of blood clots especially in patients with a history of blood clots. However, if you experience sudden chest pain, difficulty in breathing or painful swelling and redness of legs, stop taking Gestofem-400 Softgel Capsule and consult a doctor immediately as these might be signs of blood clot.

If oestrogen is used alone for hormone replacement therapy, it may increase the risk of endometrial hyperplasia (excessive thickening of uterus lining) and endometrial cancer (cancer of the womb). Oestrogen in combination with Gestofem-400 Softgel Capsule reduces this risk.

You are recommended to inform your doctor that you are taking Gestofem-400 Softgel Capsule as you may need to stop taking Gestofem-400 Softgel Capsule 4 to 6 weeks before surgery to decrease the risk of blood clot.

Gestofem-400 Softgel Capsule may increase the risk of uterine cancer. However, if you experience any unusual vaginal bleeding, please consult a doctor immediately.

Gestofem-400 Softgel Capsule is not a contraceptive. You are recommended to use additional contraceptive methods to prevent pregnancy while taking Gestofem-400 Softgel Capsule .

Gestofem-400 Softgel Capsule should be swallowed as a whole with water. Do not crush or chew it.

Gestofem-400 Softgel Capsule is a hormone extracted from plants and is chemically identical to human progesterone.

Yes, Gestofem-400 Softgel Capsule can be taken daily. Usually, it is taken once everyday in the evening or at bedtime.

Some people might gain weight due to other reasons while taking Gestofem-400 Softgel Capsule . Consult the doctor if you notice weight gain during Gestofem-400 Softgel Capsule therapy.

Yes, Gestofem-400 Softgel Capsule is safe if taken in the dose and duration prescribed by the doctor.

Progesterone plays a vital role in fertility. It improves the chances of becoming and staying pregnant by preparing the uterus lining.

Gestofem-400 Softgel Capsule may cause side effects like dizziness, drowsiness, headache, mood changes, diarrhoea, vaginal discharge, joint pain, hot flashes (sudden feeling of warmth) or constipation. If the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

75/2/16, S K Compound, Lasudiya Mori Dewas Naka Indore Indore Mp 452010 In
Other Info - GES0168

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 23, 2025 | 2:12 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.352.pdf
  2. https://www.drugs.com/progesterone.html

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