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compositionComposition:Glimepiride-2Mg+Metformin-500Mg+Pioglitazone-15Mg
prescriptionPrescription Medicine
Glimibet-PM 2 mg Tablet 10's

Glimibet-PM 2 mg Tablet 1 is used to treat type 2 diabetes. It works by reducing sugar production in the liver, delaying sugar absorption from the intestines, and removing sugar from the blood. In some cases, this medicine may cause side effects such as stomach pain, nausea, diarrhoea, vomiting, headache, metallic taste, or low blood sugar. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

Glimepiride-2Mg+Metformin-500Mg+Pioglitazone-15Mg

Manufacturer/Marketer :

Gopal Life Sciences

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Glimibet-PM 2 mg Tablet 1

Glimibet-PM 2 mg Tablet 1 belongs to a class of medicines called anti-diabetic drugs used in the treatment of type 2 diabetes, especially in patients whose blood sugar levels are not controlled by diet and exercise alone. Type 2 diabetes is a chronic (long-lasting) condition that affects the way our body processes glucose.

Glimibet-PM 2 mg Tablet 1 contains Glimepiride, Metformin, and Pioglitazone. Glimepiride lowers blood sugar by causing the pancreas to produce insulin. Metformin reduces the production of sugar in the liver and delays sugar absorption from the intestines. Pioglitazone increases the body's sensitivity to insulin. Thereby, Glimibet-PM 2 mg Tablet 1 helps to control blood sugar levels.

In some cases, you may experience stomach pain, nausea, diarrhoea, vomiting, headache, a metallic taste, or low blood sugar. Most of these side effects of Glimibet-PM 2 mg Tablet 1 do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Glimibet-PM 2 mg Tablet 1 or any other medicines, please tell your doctor. Glimibet-PM 2 mg Tablet 1 is not recommended for children. Consult your doctor if you are breastfeeding, pregnant or planning for pregnancy. Avoid alcohol consumption with Glimibet-PM 2 mg Tablet 1 as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).

Uses of Glimibet-PM 2 mg Tablet 1

Glimibet-PM 2 mg Tablet 1 is used in the treatment of type 2 diabetes mellitus. The detailed uses of Glimibet-PM 2 mg Tablet 1 are as follows:

  • Manages Type 2 Diabetes Mellitus: Glimibet-PM 2 mg Tablet 1 to treat type 2 diabetes, especially in patients whose blood sugar levels are not controlled by diet and exercise alone.
  • Reduces Risk of Diabetes-Related Complications: By effectively controlling blood sugar levels, Glimibet-PM 2 mg Tablet 1 helps reduce the risk of long-term complications such as neuropathy and cardiovascular disease.

Have a query?

Directions for Use

  • Glimibet-PM 2 mg Tablet 1 can be taken with food to avoid stomach upset or as advised by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Glimibet-PM 2 mg Tablet 1 as a whole with a glass of water.
  • Do not chew, crush or break it.

Key Benefits

  • Glimibet-PM 2 mg Tablet 1 is effective in controlling blood sugar levels in people with Type 2 Diabetes.
  • It combines three complementary antidiabetic agents to provide comprehensive glycemic control when diet, exercise, or monotherapy is insufficient.
  • Glimepiride works by stimulating beta cells in the pancreas that produce insulin. Thus, insulin helps to remove sugar from the blood.
  • Metformin works by reducing the sugar production by cells in the liver and delaying sugar absorption from the intestines. Also, it increases the sensitivity of muscle cells to insulin, which enables these cells to remove sugar more effectively from the blood.
  • Pioglitazone works by increasing the sensitivity of liver, muscle and fat cells to insulin and enabling them to remove glucose from the blood more effectively.
  • This medicine ensures long-lasting glycaemic control, reducing the frequency of dosage. It also prevents unnecessary sugar spikes.
  • Glimibet-PM 2 mg Tablet 1 manages blood glucose levels, thereby lowering the risk of complications such as nerve problems, kidney problems, eye problems, and cardiovascular disease.

How Glimibet-PM 2 mg Tablet 1 Works

Glimibet-PM 2 mg Tablet 1 contains Glimepiride, Metformin, and Pioglitazone. Glimepiride lowers blood sugar by causing the pancreas to produce insulin. Metformin reduces the production of sugar in the liver and delays sugar absorption from the intestines. Pioglitazone increases the body's sensitivity to insulin. Thereby, Glimibet-PM 2 mg Tablet 1 helps to control blood sugar levels.

Storage

Store in a cool and dry place away from sunlight
Side effects of Glimibet-PM 2 mg Tablet 10's
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

What if I have taken an overdose of Glimibet-PM 2 mg Tablet 1

Take Glimibet-PM 2 mg Tablet 1 only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include loss of consciousness, lactic acidosis (buildup of lactic acid in the blood), and pancreatitis (inflammation of the pancreas). If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • If you are allergic to Glimibet-PM 2 mg Tablet 1 or any other medicines, please tell your doctor.
  • Glimibet-PM 2 mg Tablet 1 is not recommended for children.
  • Avoid breastfeeding while taking Glimibet-PM 2 mg Tablet 1 as it may be excreted in human milk.
  • If you are pregnant or planning for pregnancy, please inform your doctor before taking Glimibet-PM 2 mg Tablet 1 as it may harm the unborn baby.
  • Glimibet-PM 2 mg Tablet 1 should be used with caution in elderly patients.
  • Avoid alcohol consumption with Glimibet-PM 2 mg Tablet 1 as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).
  • Drive only if you are alert after taking Glimibet-PM 2 mg Tablet 1.
  • Let your doctor know if you are taking any other medicines, including supplements and herbal products.

Drug-Drug Interactions

verifiedApollotooltip
MetforminIotroxic acid
Critical
MetforminIoglycamic acid
Critical

Drug-Drug Interactions

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MetforminIotroxic acid
Critical
How does the drug interact with Glimibet-PM 2 mg Tablet 10's :
Co-administration of Iotroxic acid with Glimibet-PM 2 mg Tablet 10's can increase the risk of side effects.

How to manage the interaction:
Taking Glimibet-PM 2 mg Tablet 10's with Iotroxic acid is not recommended, please consult your doctor before taking it.
MetforminIoglycamic acid
Critical
How does the drug interact with Glimibet-PM 2 mg Tablet 10's :
Co-administration of Ioglycamic acid with Glimibet-PM 2 mg Tablet 10's can increase the risk of side effects.

How to manage the interaction:
Taking Glimibet-PM 2 mg Tablet 10's with Ioglycamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIomeprol
Critical
How does the drug interact with Glimibet-PM 2 mg Tablet 10's :
Co-administration of Iomeprol with Glimibet-PM 2 mg Tablet 10's can increase the risk of side effects.

How to manage the interaction:
Taking Glimibet-PM 2 mg Tablet 10's with Iomeprol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIopamidol
Critical
How does the drug interact with Glimibet-PM 2 mg Tablet 10's :
Co-administration of Iopamidol with Glimibet-PM 2 mg Tablet 10's can increase the risk of side effects.

How to manage the interaction:
Taking Glimibet-PM 2 mg Tablet 10's with Iopamidol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIocarmic acid
Critical
How does the drug interact with Glimibet-PM 2 mg Tablet 10's :
Co-administration of Glimibet-PM 2 mg Tablet 10's and Iocarmic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Glimibet-PM 2 mg Tablet 10's with Iocarmic acid is generally avoided as it can result in an interaction. please consult your doctor before taking it.
MetforminIobitridol
Critical
How does the drug interact with Glimibet-PM 2 mg Tablet 10's :
Co-administration of Glimibet-PM 2 mg Tablet 10's and Iobitridol can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Glimibet-PM 2 mg Tablet 10's with Iobitridol is generally avoided as it can result in an interaction. Please consult your doctor before taking it.
MetforminIocetamic acid
Critical
How does the drug interact with Glimibet-PM 2 mg Tablet 10's :
Co-administration of Glimibet-PM 2 mg Tablet 10's and Iocetamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Glimibet-PM 2 mg Tablet 10's with Iocetamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIodamide
Critical
How does the drug interact with Glimibet-PM 2 mg Tablet 10's :
Co-administration of Glimibet-PM 2 mg Tablet 10's and Iodamide can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Glimibet-PM 2 mg Tablet 10's with Iodamide is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIodixanol
Critical
How does the drug interact with Glimibet-PM 2 mg Tablet 10's :
Co-administration of Iodixanol with Glimibet-PM 2 mg Tablet 10's can increase the risk of side effects.

How to manage the interaction:
Taking Glimibet-PM 2 mg Tablet 10's with Iodixanol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIofendylate
Critical
How does the drug interact with Glimibet-PM 2 mg Tablet 10's :
Co-administration of Iofendylate with Glimibet-PM 2 mg Tablet 10's can increase the risk of side effects.

How to manage the interaction:
Taking Glimibet-PM 2 mg Tablet 10's with Iofendylate is generally avoided as it can result in an interaction, please consult your doctor before taking it.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do regular exercise such as cycling, walking, jogging, dancing or swimming for a minimum of 30 minutes per day. Invest at least 150 minutes of your week in exercise.
  • Maintain a healthy body weight, as obesity is also related to the onset of diabetes.
  • Maintain a low-fat and low-sugar diet. Replace carbohydrate-containing foods with whole grains, fruits and vegetables, as carbohydrates turn to sugars, leading to high blood sugar.
  • Avoid consumption of alcohol and quit smoking.

Habit Forming

No

Therapeutic Class

[ANTIDIABETICS]

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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Glimibet-PM 2 mg Tablet 1 as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).

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Pregnancy

Unsafe

Glimibet-PM 2 mg Tablet 1 is not recommended for pregnant women as it may harm an unborn baby. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Glimibet-PM 2 mg Tablet 1 as it may be excreted in breastmilk and cause adverse effects in the baby. Therefore, please consult a doctor before using Glimibet-PM 2 mg Tablet 1 if you are breastfeeding.

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Driving

Caution

Glimibet-PM 2 mg Tablet 1 may decrease alertness in some people. Therefore, drive only if you are alert after taking Glimibet-PM 2 mg Tablet 1.

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Liver

Caution

Take Glimibet-PM 2 mg Tablet 1 with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Glimibet-PM 2 mg Tablet 1 with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Glimibet-PM 2 mg Tablet 1 is not recommended for children as the safety and effectiveness were not established.

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Heart

Glimibet-PM 2 mg Tablet 1 should be used with caution in patients with heart problems. Inform your doctor about any heart-related conditions before taking Glimibet-PM 2 mg Tablet 1.

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Geriatrics

Caution

Glimibet-PM 2 mg Tablet 1 should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Glimibet-PM 2 mg Tablet 1.

FAQs

Glimibet-PM 2 mg Tablet 1 is used in the treatment of type 2 diabetes, especially in patients whose blood sugar levels are not controlled by diet and exercise alone.

Glimibet-PM 2 mg Tablet 1 contains Glimepiride, Metformin, and Pioglitazone. Glimepiride lowers blood sugar by causing the pancreas to produce insulin. Metformin reduces the production of sugar in the liver and delays sugar absorption from the intestines. Pioglitazone increases the body's sensitivity to insulin. Thereby, Glimibet-PM 2 mg Tablet 1 helps to control blood sugar levels.

Glimibet-PM 2 mg Tablet 1 may increase the risk of low blood sugar levels, especially with alcohol intake, when you exercise more than usual, delay or miss snacks or meals. However, if you experience any signs of low blood pressure such as dizziness, nausea, light-headedness, dehydration or fainting, please consult a doctor.

You are not recommended to take Glimibet-PM 2 mg Tablet 1 with pregabalin as it may cause weight gain and fluid retention that could lead to heart failure. However, please consult a doctor before using Glimibet-PM 2 mg Tablet 1 with other medicines.

In type 1 diabetes, the body does not produce insulin as the islet cells (insulin-producing cells) in the pancreas are completely destroyed. In type 2 diabetes, though islet cells are working, the body does not respond to insulin as the body becomes resistant to it.

You are not recommended to stop taking Glimibet-PM 2 mg Tablet 1 on your own, as discontinuing Glimibet-PM 2 mg Tablet 1 suddenly may cause recurring symptoms or worsen the condition. However, if you experience any difficulty while taking Glimibet-PM 2 mg Tablet 1, please consult your doctor so that alternative medicine may be prescribed.

Yes, Glimibet-PM 2 mg Tablet 1 may cause stomach upset as a side effect. Drink water/fluids in small, frequent amounts and chew the food properly while eating.

You are recommended to avoid consumption of alcohol with Glimibet-PM 2 mg Tablet 1 as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).

Inform the doctor if you are taking any other medicines, have any other medical conditions, and if you are pregnant or breastfeeding.

Yes, Glimibet-PM 2 mg Tablet 1 may lead to vitamin B12 deficiency, particularly on long-term use. Consult the doctor if you experience symptoms of vitamin b12 deficiency such as headache, loss of appetite, fatigue, mental impairment, pins and needle sensation, and pale skin.

Store Glimibet-PM 2 mg Tablet 1 at room temperature, in a dry place. Keep out of sight and reach of children.

Glimibet-PM 2 mg Tablet 1 may cause side effects like stomach pain, nausea, diarrhoea, vomiting, headache, metallic taste, or low blood sugar. If the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

336, Industrial Area, Phase-Ii, Panchkula - 134109
Other Info - GLI0650

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Nov 18, 2025 | 7:29 AM IST

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