Glipril MF Plus Tablet 10's
MRP ₹5
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₹0.8 Cashback (15%)
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About Glipril MF Plus Tablet
Glipril MF Plus Tablet belongs to a class of medicines called anti-diabetic drugs used in the treatment of type 2 diabetes, especially in patients whose blood sugar levels are not controlled by diet and exercise alone.
Glipril MF Plus Tablet contains Glimepiride and Metformin. Glimepiride helps the pancreas release more insulin, thereby lowering blood sugar levels. Metformin reduces the amount of sugar produced by the liver, slows down sugar absorption from food, and helps the body use insulin more effectively.
In some cases, Glipril MF Plus Tablet may cause side effects like stomach pain, nausea, diarrhoea, vomiting, headache or metallic taste. Most of these side effects of Glipril MF Plus Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Do not take Glipril MF Plus Tablet if you are allergic to any of its components. Glipril MF Plus Tablet is not recommended during pregnancy, breastfeeding and in children. Avoid alcohol consumption with Glipril MF Plus Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).
Uses of Glipril MF Plus Tablet
Glipril MF Plus Tablet is used in the treatment of type 2 diabetes mellitus. The detailed uses of Glipril MF Plus Tablet are as follows:
- Management of Type 2 Diabetes: Glipril MF Plus Tablet helps lower blood sugar levels in individuals diagnosed with type 2 diabetes.
- Improvement of Insulin Sensitivity: Glipril MF Plus Tablet enhances the action of insulin, making the body's tissues more responsive to it.
- Reduction of Cardiovascular Risks: Regular use of Glipril MF Plus Tablet can help reduce the risk of cardiovascular diseases in diabetic patients.
- Control of Blood Sugar Levels Post Meals: Glipril MF Plus Tablet assists in lowering postprandial blood sugar spikes, which is beneficial for overall diabetes management.
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Directions for Use
- Glipril MF Plus Tablet can be taken with meals or as prescribed by the doctor.
- Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
- Swallow Glipril MF Plus Tablet as a whole with a glass of water.
- Do not chew, crush or break it.
Key Benefits
- Glipril MF Plus Tablet is indicated as an adjunct to diet and exercise to improve glycaemic control in patients with type 2 diabetes.
- It helps manage blood glucose levels in patients with diabetes and prevents diabetes-related complications like kidney damage, eye problems, and nerve issues.
- Glipril MF Plus Tablet contains Glimepiride and Metformin, which work together to offer a dual-action approach for effectively managing type 2 diabetes.
- Glimepiride stimulates cells in the pancreas that produce insulin, which helps remove sugar from the blood.
- Metformin reduces sugar production by cells in the liver and delays sugar absorption from the intestines. Additionally, it enhances the sensitivity of muscle cells to insulin, allowing these cells to remove sugar more effectively from the bloodstream.
How Glipril MF Plus Tablet Works
Storage
- Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
- Divide your daily food intake into smaller, more frequent meals to reduce nausea.
- Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
- Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
- Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
- Use ginger (tea, ale, or candies) to help relieve nausea.
- Get adequate rest and also avoid strenuous activities that can worsen nausea.
- Talk to your doctor about taking anti-nausea medication if your nausea is severe.
- Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
- Preventing Vomiting (Before it Happens)
- Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
- Having a small meal before taking your medication can help reduce nausea and vomiting.
- Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
- Managing Vomiting (If it Happens)
- Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
- What to Do if Vomiting Persists
- Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
- Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
- Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
- Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
- Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
- Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
- Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
- Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
- Drink water or other clear fluids.
- To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
- Include bland foods like rice, toast, crackers, and rice in your diet.
- Avoid lying down immediately after eating as it may cause indigestion or heartburn.
- Avoid acidic and spicy food as it may cause indigestion.
What if I have taken an overdose of Glipril MF Plus Tablet
Drug Warnings
- Do not take Glipril MF Plus Tablet if you are allergic to any of its components, if you have type 1 diabetes mellitus, diabetic ketoacidosis or diabetic coma.
- Inform the doctor if you have liver or kidney problems, low blood sugar, or circulation problems.
- Glipril MF Plus Tablet is not recommended for pregnant women as it may harm the unborn baby. Please consult a doctor if you are pregnant or planning to become pregnant. This medicine may pass into breast milk; therefore, it should be avoided in nursing mothers.
- Glipril MF Plus Tablet may decrease alertness in some people. Therefore, drive only if you are alert after taking Glipril MF Plus Tablet .
- Avoid alcohol consumption with Glipril MF Plus Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).
- Beware of symptoms of hypoglycemia (low blood sugar), which include sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, frequent urination, etc. Whenever you experience any of these symptoms, immediately consume candies, glucose biscuits, or honey/sugar. Make sure to carry these with you at all times, especially during long travels.
Drug-Drug Interactions
Drug-Drug Interactions
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Co-administration of Iopanoic acid with Glipril MF Plus Tablet can increase the risk of side effects.
How to manage the interaction:
Taking Glipril MF Plus Tablet with Iopanoic acid is not recommended, please consult your doctor before taking it.
Co-administration of Iohexol with Glipril MF Plus Tablet can increase the risk of side effects.
How to manage the interaction:
Taking Glipril MF Plus Tablet with Iohexol is generally avoided as it can result in an interaction, please consult your doctor before taking it.
Co-administration of Iopromide with Glipril MF Plus Tablet can increase the risk of lactic acidosis.
How to manage the interaction:
Taking Iopromide with Glipril MF Plus Tablet is not recommended, please consult a doctor before taking it. Do not discontinue the medication without consulting a doctor.
Co-administration of Iodixanol with Glipril MF Plus Tablet can increase the risk of side effects.
How to manage the interaction:
Taking Glipril MF Plus Tablet with Iodixanol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
Co-administration of Iopamidol with Glipril MF Plus Tablet can increase the risk of side effects.
How to manage the interaction:
Taking Glipril MF Plus Tablet with Iopamidol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
Co-administration of Ioglycamic acid with Glipril MF Plus Tablet can increase the risk of side effects.
How to manage the interaction:
Taking Glipril MF Plus Tablet with Ioglycamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
Co-administration of Glipril MF Plus Tablet and Iocarmic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).
How to manage the interaction:
Taking Glipril MF Plus Tablet with Iocarmic acid is generally avoided as it can result in an interaction. please consult your doctor before taking it.
Co-administration of Iomeprol with Glipril MF Plus Tablet can increase the risk of side effects.
How to manage the interaction:
Taking Glipril MF Plus Tablet with Iomeprol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
Co-administration of Iotroxic acid with Glipril MF Plus Tablet can increase the risk of side effects.
How to manage the interaction:
Taking Glipril MF Plus Tablet with Iotroxic acid is not recommended, please consult your doctor before taking it.
Co-administration of Ioglicic acid with Glipril MF Plus Tablet can increase the risk of side effects.
How to manage the interaction:
Taking Glipril MF Plus Tablet with Ioglicic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
Drug-Food Interactions
Drug-Food Interactions
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Diet & Lifestyle Advise
- Do regular exercise such as cycling, walking, jogging, dancing, or swimming for a minimum of 30 minutes per day. Invest at least 150 minutes of your week in exercise.
- Maintain a healthy body weight, as obesity is also related to the onset of diabetes.
- Maintain a low-fat and low-sugar diet. Replace carbohydrate-containing foods with whole grains, fruits, and vegetables, as carbohydrates turn to sugars, leading to high blood sugar.
- Avoid the consumption of alcohol and quit smoking.
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Alcohol
Safe if prescribed
You are recommended to avoid consumption of alcohol with Glipril MF Plus Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).
Pregnancy
Consult your doctor
Glipril MF Plus Tablet is not recommended for pregnant women as it may harm the unborn baby. Please consult a doctor if you are pregnant or planning for pregnancy.
Breast Feeding
Consult your doctor
Avoid breastfeeding while taking Glipril MF Plus Tablet as it may be excreted in breastmilk and cause adverse effects in the baby. Therefore, please consult a doctor before using Glipril MF Plus Tablet if you are breastfeeding.
Driving
Safe if prescribed
Glipril MF Plus Tablet may decrease alertness in some people. Therefore, drive only if you are alert after taking Glipril MF Plus Tablet .
Liver
Consult your doctor
Take Glipril MF Plus Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.
Kidney
Consult your doctor
Take Glipril MF Plus Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.
Children
Safe if prescribed
Glipril MF Plus Tablet is not recommended for children as the safety and effectiveness were not established.
Heart
Glipril MF Plus Tablet should be taken with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems before using Glipril MF Plus Tablet .
Geriatrics
Consult your doctor
Glipril MF Plus Tablet should be given with caution in elderly patients due to an increased risk of side effects. If you have any concerns about the usage of Glipril MF Plus Tablet in geriatrics, please consult your doctor.
FAQs
Glipril MF Plus Tablet is indicated in the treatment of type 2 diabetes mellitus.
Glipril MF Plus Tablet works by decreasing the amount of glucose absorbed from the food and the amount of glucose made by the liver. It helps the pancreas to produce insulin and helps the body use insulin efficiently.
Glipril MF Plus Tablet may increase the risk of low blood sugar levels, especially with alcohol intake, exercise more than usual, delay or miss snacks or meals. However, if you experience any signs of low blood pressure, such as dizziness, nausea, light-headedness, dehydration or fainting, please consult a doctor.
In type 1 diabetes, the body does not produce insulin as the islet cells (insulin-producing cells) in the pancreas are destroyed completely. In type 2 diabetes, though islet cells are working, the body doesn't respond to insulin as the body becomes resistant to it.
You are not recommended to stop taking Glipril MF Plus Tablet on your own as discontinuing Glipril MF Plus Tablet suddenly may cause recurring symptoms or worsen the condition. However, if you experience any difficulty while taking Glipril MF Plus Tablet , please consult your doctor so that alternative medicine may be prescribed.
You are not recommended to take Glipril MF Plus Tablet with phenytoin as it may reduce the effect of Glipril MF Plus Tablet and increase blood sugar levels. However, please consult a doctor before using Glipril MF Plus Tablet with other medicines.
Include a diet rich in fruits, vegetables and whole grains like brown rice, whole wheat, oats, barley, and quinoa. Non-fat or low-fat dairy and proteins like chicken, lean meats, nuts, beans, tofu, lentils, eggs, fish, and turkey can also be included.
Cut back on foods high in sodium, alcohol, fried foods, and high-carb food and drinks like sugary drinks, drinks with added sugar, white rice and starchy vegetables.
You are advised to take Glipril MF Plus Tablet for the duration recommended by the doctor.
Store Glipril MF Plus Tablet at room temperature, in a dry place. Keep out of sight and reach of children.
Glipril MF Plus Tablet may cause lactic acidosis (builds up of lactic acid in the blood). Consult the doctor if you notice symptoms of lactic acidosis like abdominal pain, vomiting, muscle cramps, difficulty breathing, reduced body temperature and heartbeat, and severe tiredness.
Glipril MF Plus Tablet is an anti-diabetic medicine used to treat type 2 diabetes mellitus, also known as noninsulin-dependent diabetes mellitus.
Side effects of Glipril MF Plus Tablet are stomach pain, nausea, diarrhoea, vomiting, headache or metallic taste. Most of these side effects may not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Long-term use of Glipril MF Plus Tablet may lead to vitamin B12 deficiency. Regular monitoring of vitamin B12 levels is recommended.
You are recommended to avoid consumption of alcohol with Glipril MF Plus Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).
Glipril MF Plus Tablet should be swallowed as a whole with water; do not crush, break or chew it.
Regularly monitor blood glucose levels. Have your meals regularly and never miss a meal. Always carry a source of sugar and consume it if you experience low blood sugar. If you are due to undergo any tests or surgery, inform the doctor that you are taking Glipril MF Plus Tablet . Avoid drinking alcohol.
Other medicines should be taken with Glipril MF Plus Tablet only if prescribed by the doctor. To prevent any interactions it is advised to consult the doctor before taking other medicines during treatment with Glipril MF Plus Tablet .
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Reference
- https://www.sanofi.in/-/media/Project/One-Sanofi-Web/Websites/Asia-Pacific/Sanofi-IN/Home/science-and-innovation/for-healthcare-professionals/product-information/Amaryl-M-PI--May-2018.pdf?la=en
- https://www.tmda.go.tz/uploads/1678353865-T20H0128SmPCV1.pdf
- https://www.nafdac.gov.ng/wp-content/uploads/Files/SMPC/Feb_2022/Co-mepiryl-Forte.pdf
- https://www.centaurpharma.com/downloads/Glimitab-M2018.pdf
- https://simsrc.edu.in/pdf_df/M-drugs/Metformin%20+%20glimepiride.pdf
