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compositionComposition:GLIMEPIRIDE-2MG+METFORMIN-500MG
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Prescription Medicine
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Glimestar M 2 Tablet is used to treat type 2 diabetes. It helps manage blood glucose levels in patients with diabetes and prevents diabetes-related complications like kidney damage, eye problems, and nerve issues.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

GLIMEPIRIDE-2MG+METFORMIN-500MG

Manufacturer/Marketer :

Mankind Pharma Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Glimestar M 2 Tablet

Glimestar M 2 Tablet is a prescription oral tablet used to manage type 2 diabetes in adults. This medicine helps control blood sugar levels when diet and exercise alone are not enough. It is designed to keep your blood sugar within a healthy range to prevent long-term health complications.

For the best results, you must take Glimestar M 2 Tablet consistently every day as prescribed by your doctor. It is typically taken with meals, which helps reduce the chance of experiencing stomach upset. Combining this medicine with a balanced diet and regular physical activity is essential to achieve proper blood sugar control.

Some people may experience mild side effects, such as a temporary upset stomach or a metallic taste in the mouth. However, you should contact your doctor immediately if you experience signs of extremely low blood sugar, such as sweating, shaking, or confusion. Severe symptoms like persistent vomiting, deep rapid breathing, or unusual muscle pain also require urgent medical advice.

Before taking Glimestar M 2 Tablet , tell your doctor if you have kidney or liver issues, heart problems, or severe dehydration. Do not take this if you have type 1 diabetes, severe kidney failure, or diabetic ketoacidosis (a serious complication of diabetes). It is also unsafe for those with severe liver damage.

This medicine can interact with alcohol, which can dangerously increase the risk of low blood sugar or a rare but serious acid buildup in the blood. You should also tell your doctor about all other medicines you take, as some can affect how this tablet works. If you are pregnant, breastfeeding, or are an elderly individual, consult your doctor before starting this treatment to ensure it is safe for you.

Uses of Glimestar M 2 Tablet

Glimestar M 2 Tablet is used to treat Type 2 diabetes mellitus. The detailed uses of Glimestar M 2 Tablet are as follows:

  • Type 2 Diabetes Mellitus: Glimestar M 2 Tablet helps lower high blood sugar levels in adults whose diabetes cannot be controlled by diet, exercise, and single-medicine therapy alone.
  • Prevention of Diabetes Complications: By maintaining stable blood sugar levels, this medicine helps reduce the risk of serious long-term issues like kidney damage, nerve problems, blindness, and loss of limbs.

Key Benefits

Glimestar M 2 Tablet helps manage type 2 diabetes by combining two complementary blood sugar-lowering medicines in a single daily tablet. With regular use, it helps maintain stable blood sugar levels, improves daily well-being, and reduces the risk of long-term diabetes-related complications.

  • Provides Stable Blood Sugar Control: By lowering blood sugar through two different mechanisms, this medicine helps keep blood glucose levels within a healthy range, reducing symptoms such as excessive thirst, frequent urination, and energy fluctuations.
  • Improves Daily Well-Being: Maintaining stable blood sugar levels helps prevent sudden energy crashes, allowing you to stay more active and feel better throughout the day.
  • Protects Against Long-Term Complications: Consistent blood sugar control helps protect your blood vessels and vital organs, reducing the risk of complications such as kidney damage, nerve damage, vision problems, and cardiovascular disease.

Directions for Use

  • Glimestar M 2 Tablet can be taken with meals or as prescribed by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Glimestar M 2 Tablet as a whole with a glass of water.
  • Do not chew, crush or break it.

How Glimestar M 2 Tablet Works

Glimestar M 2 Tablet works through a dual-action mechanism to control blood sugar levels. It contains two active ingredients that target different pathways in the body to manage type 2 diabetes effectively. The first active ingredient, glimepiride, which works by stimulating the pancreas to release more insulin, which is the natural hormone that helps your body process sugar. This helps lower the amount of glucose circulating in your bloodstream after meals. The second active ingredient, metformin, which works in two ways: it reduces the amount of sugar your liver produces and improves your body's sensitivity to insulin. This allows your muscles and tissues to absorb and use sugar from the blood more efficiently. Together, these two actions provide a highly effective way to keep your blood sugar within a target range.
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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Glimestar M 2 Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).

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Pregnancy

Unsafe

Glimestar M 2 Tablet is not recommended for pregnant women as it may harm the unborn baby. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Glimestar M 2 Tablet as it may be excreted in breastmilk and cause adverse effects in the baby. Therefore, please consult a doctor before using Glimestar M 2 Tablet if you are breastfeeding.

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Driving

Caution

Glimestar M 2 Tablet may decrease alertness in some people. Therefore, drive only if you are alert after taking Glimestar M 2 Tablet .

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Liver

Caution

Take Glimestar M 2 Tablet with caution, especially if you have a history of liver diseases. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Glimestar M 2 Tablet with caution, especially if you have a history of kidney diseases. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Glimestar M 2 Tablet is not recommended for children as the safety and effectiveness were not established.

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Heart

Caution

Glimestar M 2 Tablet should be taken with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems before using Glimestar M 2 Tablet .

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Geriatrics

Caution

Glimestar M 2 Tablet should be given with caution in elderly patients due to an increased risk of side effects. If you have any concerns about the usage of Glimestar M 2 Tablet in geriatrics, please consult your doctor.

What if I have taken an overdose of Glimestar M 2 Tablet

If you suspect an overdose, seek immediate medical attention or contact a poison control center right away. An overdose can cause severe low blood sugar or a dangerous buildup of acid in your blood, which requires urgent treatment in a hospital.

Diet & Lifestyle Advise

  • Monitor your carbohydrates: Focus on complex carbohydrates like whole grains, vegetables, and legumes, which release sugar slowly into your bloodstream, rather than simple sugars and refined flours.
  • Stay consistently active: Aim for at least 150 minutes of moderate physical activity, such as brisk walking, each week, as regular exercise helps your body use insulin more effectively.
  • Eat meals at regular times: Avoid skipping meals, especially when taking Glimestar M 2 Tablet , to prevent sudden drops in your blood sugar levels.
  • Keep a fast-acting sugar source nearby: Always carry a source of fast-acting sugar, such as fruit juice, hard candy, or glucose tablets, in case you experience symptoms of low blood sugar.
  • Stay hydrated: Drink plenty of water throughout the day to support your kidney function and help your body process the medication safely.

Health Queries

Can taking Glimestar PM2 and Neurobian-Forte cause weight gain or other side effects for someone with a morning blood sugar of 119 and an after-meal blood sugar of 194?

Dr. S Aneela

Dr. S Aneela

M. Pharm (Pharmacology)., PhD

Yes, Glimestar PM2 (which contains glimepiride, pioglitazone, and metformin) can cause weight gain, primarily due to the glimepiride and pioglitazone components. Neurobion-Forte, a vitamin B complex, does not cause weight gain. Other potential side effects of your diabetes medication include mild digestive changes or low blood sugar. Your fasting blood sugar of 119 mg/dL is reasonable, but the after-meal reading of 194 mg/dL is slightly elevated, suggesting your treatment plan may need a gentle adjustment.

Given that my morning and after-meal blood sugar levels have decreased over the past 20 days while taking Glimestar PM2 and Neurobion-Forte, exercising, and dieting, what additional lifestyle tips can you share to help me continue improving my health?

Dr. S Aneela

Dr. S Aneela

M. Pharm (Pharmacology)., PhD

Your dedication is truly paying off! To continue this positive trend, try prioritizing 7?8 hours of quality sleep each night, as consistent rest directly impacts insulin sensitivity. Stay well-hydrated with water throughout the day, and practice simple stress-relief techniques like deep breathing, which help prevent cortisol-induced sugar spikes. Lastly, focus on adding more soluble fiber, like oats and legumes, to your meals to further stabilize glucose.

Is a post-meal blood sugar level of 118 normal for someone with diabetes who is taking Glimestar PM2 and Neurobion-Forte?

Dr. S Aneela

Dr. S Aneela

M. Pharm (Pharmacology)., PhD

For adults managing diabetes, a typical post-meal target is under 180 mg/dL, so your reading shows wonderful control. This indicates that your daily routine and your medications?Glimestar PM2 (which contains glimepiride, pioglitazone, and metformin) and Neurobion-Forte (a vitamin B-complex supplement)?are working very well together. Please continue taking your prescribed doses, maintain your healthy habits, and share these encouraging results with your doctor during your next visit.

I have been diabetic for 8 years and take two Glimestar M-2 tablets daily. My FBS is 140-160 and PBS is 250-280, with urine sugar at 1.5.

Dr. S Aneela

Dr. S Aneela

M. Pharm (Pharmacology)., PhD

Your fasting blood sugar of 140-160 and post-meal levels of 250-280, along with sugar in urine, show that your current diabetes treatment with Glimestar M?2 is not adequately controlling your sugar. It is important to consult your doctor, who may adjust your medication, add another medicine if needed, and guide you on diet, exercise, and regular monitoring to bring your blood sugar within a safer range and prevent complications.

What could be causing my acidity and heartburn while taking GLIMESTAR M2 for diabetes?

Dr. S Aneela

Dr. S Aneela

M. Pharm (Pharmacology)., PhD

GLIMESTAR M2 itself usually does not cause acidity, but diabetes can slow stomach emptying and increase reflux, leading to heartburn. Other factors, such as diet (especially spicy or fatty foods) and irregular meals, can also trigger acidity, so managing lifestyle alongside medicines helps reduce symptoms.
health query

Have a query?

How Soon It Starts Working

The time required for Glimestar M 2 Tablet to start to work: Glimestar M 2 Tablet ideally shows its action within few hours after administration. 

The time for which the effects of Glimestar M 2 Tablet last: The duration of action for Glimestar M 2 Tablet is clinically unknown.

What if you forget to take Glimestar M 2 Tablet

If you miss a dose, take it with your next meal if it is close to your scheduled time. However, if it is almost time for your next regular dose, skip the missed dose and resume your normal schedule. Do not take two doses at the same time to make up for a missed one, as this can cause your blood sugar to drop dangerously low.

Storage

•Store Glimestar M 2 Tablet at room temperature, ideally between 20°C and 25°C (68°F to 77°F). •Keep the tablets in their original packaging to protect them from moisture and direct light.

Drug Warnings

  • Monitor your blood sugar regularly: Check your blood sugar levels as directed by your doctor to ensure the medicine is working safely and effectively.
  • Inform healthcare providers before surgery: Tell any surgeon, dentist, or doctor that you are taking Glimestar M 2 Tablet , as you may need to stop taking it temporarily before certain procedures or medical scans using contrast dyes.
  • Limit alcohol consumption: Avoid heavy drinking while taking this medicine, as alcohol significantly increases the risk of severe low blood sugar and lactic acid buildup.
  • Watch for signs of dehydration: Severe vomiting, diarrhoea, or not drinking enough fluids can increase the risk of serious side effects; contact your doctor if you cannot keep fluids down.
  • Check your feet daily: Diabetes can affect circulation and nerve health; inspect your feet regularly for any cuts, sores, or infections and report them to your doctor.

Drug-Drug Interactions

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Drug-Drug Interaction Summary:

  • Water pills (diuretics) and steroids: May raise your blood sugar levels, making Glimestar M 2 Tablet less effective.
  • Heart medicines (like beta-blockers): Can hide the warning signs of low blood sugar, such as a rapid heart rate.
  • Pain relievers (like NSAIDs) and certain blood pressure drugs: May increase the risk of kidney problems when combined with this medicine.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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Drug-Food Interaction Summary:

  • Alcohol: Interacts dangerously by increasing the risk of extremely low blood sugar and a serious buildup of lactic acid in the blood.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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FAQs

Glimestar M 2 Tablet is indicated in the treatment of type 2 diabetes mellitus.
Glimestar M 2 Tablet works by decreasing the amount of glucose absorbed from the food and the amount of glucose made by the liver. It helps the pancreas to produce insulin and helps the body use insulin efficiently.
In type 1 diabetes, the body does not produce insulin as the islet cells (insulin-producing cells) in the pancreas are destroyed completely. In type 2 diabetes, though islet cells are working, the body doesn't respond to insulin as the body becomes resistant to it.
You are not recommended to stop taking Glimestar M 2 Tablet on your own as discontinuing Glimestar M 2 Tablet suddenly may cause recurring symptoms or worsen the condition. However, if you experience any difficulty while taking Glimestar M 2 Tablet , please consult your doctor so that alternative medicine may be prescribed.
Include a diet rich in fruits, vegetables and whole grains like brown rice, whole wheat, oats, barley, and quinoa. Non-fat or low-fat dairy and proteins like chicken, lean meats, nuts, beans, tofu, lentils, eggs, fish, and turkey can also be included.
Store Glimestar M 2 Tablet at room temperature, in a dry place. Keep out of sight and reach of children.
Glimestar M 2 Tablet may cause lactic acidosis (builds up of lactic acid in the blood). Consult the doctor if you notice symptoms of lactic acidosis like abdominal pain, vomiting, muscle cramps, difficulty breathing, reduced body temperature and heartbeat, and severe tiredness.
Side effects of Glimestar M 2 Tablet are stomach pain, nausea, diarrhoea, vomiting, headache or metallic taste. Most of these side effects may not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Long-term use of Glimestar M 2 Tablet may lead to vitamin B12 deficiency. Regular monitoring of vitamin B12 levels is recommended.
Glimestar M 2 Tablet should be swallowed as a whole with water; do not crush, break or chew it.
Regularly monitor blood glucose levels. Have your meals regularly and never miss a meal. Always carry a source of sugar and consume it if you experience low blood sugar. If you are due to undergo any tests or surgery, inform the doctor that you are taking Glimestar M 2 Tablet . Avoid drinking alcohol.
Other medicines should be taken with Glimestar M 2 Tablet only if prescribed by the doctor. To prevent any interactions it is advised to consult the doctor before taking other medicines during treatment with Glimestar M 2 Tablet .
It is highly recommended to avoid or strictly limit alcohol while taking Glimestar M 2 Tablet . Alcohol can cause your blood sugar to drop dangerously low and increase the risk of a rare but serious condition called lactic acidosis, which is an acid buildup in your blood. Talk to your doctor about safe alcohol limits for you.
If you experience signs of low blood sugar, such as shaking, sweating, or dizziness, immediately consume 15 to 20 grams of fast-acting sugar (like half a cup of fruit juice or 3 to 4 glucose tablets). Check your blood sugar again after 15 minutes. If symptoms persist or if you feel confused, seek immediate medical help. Talk to your doctor about how to manage these episodes.
Some patients may experience mild weight loss or a stable weight while taking this medication, primarily due to how one of the active ingredients affects insulin use and appetite. However, Glimestar M 2 Tablet is not a weight-loss drug and should only be used to manage blood sugar. Talk to your doctor for advice on managing your weight.
Glimestar M 2 Tablet is generally not recommended during pregnancy or breastfeeding, as alternative treatments are usually preferred to manage blood sugar during these times. If you are planning a pregnancy or become pregnant while taking this medicine, contact your healthcare provider immediately. Talk to your doctor to discuss safer alternatives.
Glimestar M 2 Tablet does not typically cause kidney damage, but your kidneys are responsible for clearing this medicine from your body. If your kidney function declines, the medicine can build up and cause serious side effects. Your doctor will perform routine blood tests to check your kidney health. Talk to your doctor if you have concerns about your kidneys.
You must temporarily stop taking Glimestar M 2 Tablet before or at the time of any imaging test that uses iodinated contrast dye, as the dye can temporarily affect your kidney function and increase the risk of a serious blood acid buildup. You can usually restart the medicine 48 hours after the procedure once your kidney function is checked. Talk to your doctor for specific instructions.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

208, Okhla Industrial Estate, Phase III, New Delhi - 110020

Therapeutic Class

[ANTIDIABETICS]

Habit Forming

No
Other Info - GLI0015
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