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About Globucel VF 10% Solution 100 ml
Globucel VF 10% Solution 100 ml belongs to the class of medications called ‘immunising agents’ used to treat immunoglobulin (antibody) deficiency and certain inflammatory disorders. It is used to treat immunoglobulin deficiency in people with primary immunodeficiency or PID (present from birth) and secondary immunodeficiency or SID (developed in the later stages of life). Globucel VF 10% Solution 100 ml is also used to treat inflammatory disorders such as primary immune thrombocytopenia (reduced number of platelets), Guillain-Barre syndrome (short-term inflammation of the peripheral nerves causing weakness of legs and upper limbs), Kawasaki disease (inflammation of blood vessels in children), chronic inflammatory demyelinating polyneuropathy or CIDP (long-term inflammation of peripheral nerves), and multifocal motor neuropathy (progressive disease leading to weakness of arms and legs).
Globucel VF 10% Solution 100 ml contains ‘Human normal immunoglobulin’, which replaces the deficient antibodies necessary to act against infections and inflammation. It works exactly as the immunoglobulins present in the body. Immunoglobulins are an essential part of the immune system, which recognises the antigens or foreign elements in the body and aids in their destruction. It also helps to reduce inflammation by improving immunity.
Globucel VF 10% Solution 100 ml will be administered by a trained healthcare professional; hence do not self-administer. This may cause side effects such as swelling or hardening at the injection site and headache, pain in the face, back, arms, legs, joints, or neck, fever, flu-like illness (runny nose and sore throat), blisters in the mouth, and throat, and throat tightness. These side effects are usually mild and temporary. However, if any of the side effects persist or get worse, inform your doctor immediately.
It is not recommended to take Globucel VF 10% Solution 100 ml if you are allergic to any of its contents or have blood clotting disorders. Before taking Globucel VF 10% Solution 100 ml, inform your doctor if you have had any vaccinations recently or have already had this product recently. Globucel VF 10% Solution 100 ml should be used with caution in people with immunoglobulin A (IgA) deficiency (IgA is a type of antibody that protects against infections). Globucel VF 10% Solution 100 ml is probably safe when given to children, pregnant women, and breastfeeding mothers. Globucel VF 10% Solution 100 ml should be used with caution in elderly people. Globucel VF 10% Solution 100 ml may not interact with alcohol. Globucel VF 10% Solution 100 ml may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.
Uses of Globucel VF 10% Solution 100 ml
Directions for Use
Medicinal Benefits
Globucel VF 10% Solution 100 ml acts by replacing the deficient antibodies that are necessary to act against infections and inflammation. It works exactly as the immunoglobulins present in the body. Immunoglobulins are an important part of the immune system, which recognizes the antigens or foreign elements in the body and causes their destruction. It is used to treat immunoglobulin deficiency in people with primary immunodeficiency or PID (present from birth) and secondary immunodeficiency or SID (developed in the later stages of life). Globucel VF 10% Solution 100 ml is also used to treat inflammatory disorders such as primary immune thrombocytopenia (reduced number of platelets), Guillain-Barre syndrome (short-term inflammation of the peripheral nerves causing weakness of legs and upper limbs), Kawasaki disease (inflammation of blood vessels in children), chronic inflammatory demyelinating polyneuropathy or CIDP (long-term inflammation of peripheral nerves), and multifocal motor neuropathy (progressive disease leading to weakness of arms and legs).
How Globucel VF 10% Solution 100 ml Works
Storage
What if I have taken an overdose of Globucel VF 10% Solution 100 ml
Drug Warnings
Globucel VF 10% Solution 100 ml should be used with caution in people with immunoglobulin A (IgA) deficiency (IgA is a type of antibody that protects against infections) as there is an increased risk of allergic reactions. Globucel VF 10% Solution 100 ml may cause a sudden fall in blood pressure with an allergic reaction, including shock, even in patients who have tolerated previous treatment with this medicine. So, it is advised to monitor patients during infusion and at least 20 min after the infusion. If you develop a severe headache, drowsiness, fever, neck stiffness, sensitivity to light, nausea, and vomiting after Globucel VF 10% Solution 100 ml, inform your doctor immediately. It may signify aseptic meningitis syndrome (severe inflammation of the brain's linings). Globucel VF 10% Solution 100 ml should be used with caution in people with obesity or overweight, diabetes, high blood pressure (hypertension), hypovolemia (low blood volume), and blood clotting disorders, as there is a risk of developing a blood clot (very rare effect of Globucel VF 10% Solution 100 ml). So, inform your doctor if you notice any sign of a blood clot, such as pain, swelling and unusual warmth of a limb, weakness on one side of the body, confusion, sudden shortness of breath, chest pain worsening on deep breathing, and difficulty speaking. Globucel VF 10% Solution 100 ml should be used with caution in patients with kidney problems or who have taken medicines that may harm kidneys (nephrotoxic drugs) as Globucel VF 10% Solution 100 ml may cause problems with kidney function in these people. In rare cases, Globucel VF 10% Solution 100 ml may cause non-cardiogenic pulmonary oedema (accumulation of fluid in the lungs' air spaces, which is a non-heart related condition). In such cases, patients may experience breathing difficulty, bluish skin, and very low oxygen levels in the blood.
Drug-Drug Interactions
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Diet & Lifestyle Advise
Habit Forming
Therapeutic Class
Alcohol
Safe if prescribed
Globucel VF 10% Solution 100 ml may not interact with alcohol. However, limit or avoid consumption of alcohol to avoid possible side effects.
Pregnancy
Safe if prescribed
Inform your doctor if you are pregnant or planning pregnancy before receiving Globucel VF 10% Solution 100 ml. Your doctor will assess the benefits and the risks before prescribing.
Breast Feeding
Safe if prescribed
Inform your doctor if you are breastfeeding before receiving Globucel VF 10% Solution 100 ml. Your doctor will assess the benefits and the risks before prescribing.
Driving
Caution
Globucel VF 10% Solution 100 ml may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy after receiving this medicine.
Liver
Caution
Globucel VF 10% Solution 100 ml should be used with caution in patients with liver diseases. Your doctor may adjust the dose if necessary based on your condition.
Kidney
Caution
Globucel VF 10% Solution 100 ml should be used with caution in patients with kidney diseases. Your doctor may adjust the dose if necessary based on your condition.
Children
Safe if prescribed
Globucel VF 10% Solution 100 ml can be safely used in children when prescribed.
Have a query?
Globucel VF 10% Solution 100 ml is used to treat immunoglobulin (antibody) deficiency and certain inflammatory disorders.
The Globucel VF 10% Solution 100 ml contains 'Human normal immunoglobulin', which helps restore the deficient immunoglobulins or antibodies in the body. Antibodies are an essential part of the immune system that helps to reduce infection and inflammation. They act by identifying, attacking, and thereby destroying the antigen or foreign body that has entered or is present in the body.
Globucel VF 10% Solution 100 ml may alter some blood test results for a certain time, so inform your doctor that you have Globucel VF 10% Solution 100 ml before undergoing blood tests. Taking any vaccines (especially live vaccines) at least three months after taking Globucel VF 10% Solution 100 ml is not recommended as this medicine may make the vaccines less effective.
Globucel VF 10% Solution 100 ml should be used with caution in patients with diabetes if this medicine is given as an infusion, as it may alter blood sugar levels. Globucel VF 10% Solution 100 ml doesn’t contain sugar; however, it can be diluted in a special sugar solution before giving the infusion.
Globucel VF 10% Solution 100 ml is usually well-tolerated. However, some patients may experience side effects such as swelling or hardening at the injection site and headache, pain in the face, back, arms, legs, joints, or neck, fever, flu-like illness (runny nose and sore throat), blisters in the mouth, and throat, and throat tightness. If any side effects persist or get worse, inform your doctor immediately.
It is a condition in which there is a decrease in antibody levels in the body due to decreased ability or inability to produce enough antibodies. It can be present from birth (primary) or acquired during the later stages of life (secondary).
Certain vaccinations, such as those for chickenpox, measles, mumps, and rubella, may become less effective when administered with Globucel VF 10% Solution 100 ml. Therefore, before receiving any vaccinations, inform your doctor if you are allergic to Globucel VF 10% Solution 100 ml. Let your doctor know that you are taking Globucel VF 10% Solution 100 ml. And also inform your doctor if you are breastfeeding, pregnancy or planning pregnancy.
No, you should not discontinue using Globucel VF 10% Solution 100 ml without consulting your doctor, even if you feel fine. Stopping the usage of Globucel VF 10% Solution 100 ml early can increase the risk of infections. Always follow your doctor's instructions and complete the prescribed course of treatment to ensure the best outcome.
The effects of Globucel VF 10% Solution 100 ml can vary depending on the individual and the condition being treated. Generally, it may take up to 4 weeks of regular therapy to notice a steady improvement in your symptoms. Therefore, complete the full course of treatment as prescribed by your doctor.
Yes, Globucel VF 10% Solution 100 ml can cause kidney damage but not in everyone. Patients having a pre-existing kidney problem, hypovolemia (a decrease in the volume of circulating blood) and diabetes are at risk of developing kidney failure. Additionally, patients who are overweight, above 65 years of age and who are taking medicines that can cause kidney damage are also at risk of developing kidney failure. Therefore, please inform your doctor if you have any pre-existing kidney problems.
No, hair loss is not a commonly reported side effect of Globucel VF 10% Solution 100 ml. If you experience hair loss, it might be due to some other underlying problem. Please consult your doctor if bothers you.
Globucel VF 10% Solution 100 ml benefits people with weakened immune systems, such as those who have undergone bone marrow transplants or have severely reduced antibody-forming capacity. It can also treat or prevent infections who are suffering with measles, hepatitis, and mumps. It is used for patients with primary immunodeficiency syndromes (PID) and acquired or secondary immunodeficiency (SID). Please consult your doctor if you have any concerns.
If you are pregnant, take your doctor’s advice before using Globucel VF 10% Solution 100 ml. Your doctor will assess the benefits and risks of Globucel VF 10% Solution 100 ml before prescribing.
Store Globucel VF 10% Solution 100 ml in a refrigerator (2 - 8°C). Do not freeze. Protect it from light. Keep out of reach of children.
No, Globucel VF 10% Solution 100 ml should not be self-administered. It is usually administered by a healthcare professional, such as a doctor or nurse.
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