Glocarbazin 50mg Tablet

Glocarbazin 50mg Tablet belongs to the group of anti-cancer drugs and chemotherapeutic agents. Glocarbazin 50mg Tablet is used to treat cancers and malignant conditions such as Hodgkin’s disease (cancer that originates in the white blood cells) and certain brain tumours.

Glocarbazin 50mg Tablet contains ‘’Procarbazine.’’ Cancer is an uncontrolled growth of cells in the body. Glocarbazin 50mg Tablet interferes with the growth of cells, nipping it in the bud. It functions by inhibiting the molecular production of materials such as proteins and DNA necessary for cell growth and division.

Glocarbazin 50mg Tablet is a prescription-only medicine. It may be taken as a tablet at the same time every day. Glocarbazin 50mg Tablet may be taken with or without food. It should be swallowed as a whole and not chewed or broken down. Avoid consuming Glocarbazin 50mg Tablet with certain foods like cheese, smoked fish, fermented wine and meat.

In some cases, Glocarbazin 50mg Tablet may cause common side effects such as nausea, vomiting, bruising, cramps, rash and loss of appetite. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist.

It is advisable to inform your doctor if you are allergic to Glocarbazin 50mg Tablet or any of its components. Keep your doctor informed if you suffer from kidney or liver disease, bleeding problems, anaemia or recurrent infections. Keep your doctor informed if you are on any radiation therapy. Consult your doctor if you are pregnant, planning pregnancy or breastfeeding before taking Glocarbazin 50mg Tablet as Glocarbazin 50mg Tablet is not recommended for routine use in these states. Consult your doctor before taking alcohol with Glocarbazin 50mg Tablet as there may be an interaction. Avoid smoking while taking Glocarbazin 50mg Tablet.

Glocarbazin 50mg Tablet is an antineoplastic/anti-cancer drug. It contains PROCARBAZINE. It is used primarily in the treatment of cancers, especially Hodgkin’s lymphoma. Glocarbazin 50mg Tablet shows antineoplastic activity, meaning it targets neoplastic (abnormally growing cells) in the body and inhibits their uncontrolled division and growth. Glocarbazin 50mg Tablet works by preventing DNA, RNA and protein synthesis required for the molecular development of cells. Glocarbazin 50mg Tablet also acts by destroying DNA, thereby arresting cell growth in the roots. Hence, Glocarbazin 50mg Tablet is very effective in cancer therapy.

• Vomiting
• Nausea
• Stomach cramps
• Rash             
• Bruising
• Loss of appetite
• Hair loss
• Joint pains
• Difficulty sleeping

Glocarbazin 50mg Tablet should not be used in case of any known allergy to either of the components. Avoid foods such as processed cheese, smoked fish, meats, overripe fruit, fermented wine, and yeast while taking Glocarbazin 50mg Tablet. Glocarbazin 50mg Tablet should be used with caution in case of high-risk or previous history cancers, cardiovascular health disorders, bleeding disorders, kidney disease, liver disease or anaemia. Keep your doctor informed of your medical history and if you suffer from epilepsy, an adrenal tumour such as phaeochromocytoma, or have had a stroke. Consult your doctor before using Glocarbazin 50mg Tablet during pregnancy, breastfeeding, or even if you are trying to get pregnant. Keep your doctor informed if you are on painkillers or using any nasal decongestants or anti-anxiety, anti-depressant, antiepileptic, anaesthetic or analgesic medications. Keep your doctor informed in case you are undergoing any radiation therapy. Inform your doctor of your vaccination history and do not take any vaccines without consent. Avoid contact with those who have recently received live vaccines (like the nasal flu, pox, or MMR vaccine). Glocarbazin 50mg Tablet makes your skin more sensitive to UV radiation. Wear sunscreen and protective clothing while venturing out in the sun. Glocarbazin 50mg Tablet may interact with alcohol, please consult your doctor before use. Glocarbazin 50mg Tablet may cause dizziness and is not recommended to take while driving or operating heavy machinery.

Drug-Drug Interactions: Glocarbazin 50mg Tablet may interact with painkillers (pethidine), ADHD medicines (atomoxetine, bupropion, buspirone), anti-migraine drugs (triptans), narcotics (methadone, tapentadol), certain supplements (such as tryptophan, tyramine), certain drugs for Parkinson's disease (entacapone, levodopa, tolcapone), diet-pills and food suppressants (diethylpropion), antipsychotic (clozapine), antihypertensives (ramipril, enalapril, losartan), antiepileptics (phenytoin, carbamazepine) and anti-depressants (fluoxetine, duloxetine, venlafaxine, St John’s wort).

Drug-Food Interactions: Glocarbazin 50mg Tablet can interact with alcohol and tobacco.

Drug-Disease Interactions: Glocarbazin 50mg Tablet should be used with caution in patients with a known hypersensitivity disorder, asthma, diabetes mellitus, epilepsy, stroke, heart failure, liver disease, kidney disease, blood disorder, clotting problems and non-cancerous tumours such as phaeochromocytoma.

• ATOMOXETINE
• BUSPIRONE
• SUMATRIPTAN
• PETHIDINE
• METHADONE
• TAPENTADOL
• TRYPTOPHAN
• RAMIPRIL
• ENALAPRIL
• LOSARTAN
• PHENYTOIN
• CARBAMAZEPINE
• CLOZAPINE
• FLUOXETINE
• DULOXETINE
• ENTACAPONE
• LEVODOPA

• Keep your doctor informed if you are planning to or are pregnant.

• Cancer can take a toll on anyone. Make sure you regularly see a therapist and take care of your mental health.

• Meditation and yoga have also proven very effective in helping cancer patients maintain a healthy attitude and body.

• Cut back on foods that are high in tyramine such as overripe fruit, processed cheese, smoked fish, meat etc. Eat more healthy meats, healthy fats, fruits, vegetables and whole-grain foods to give you more energy.

• Avoid taking Glocarbazin 50mg Tablet with alcohol as there may be an interaction.

• Stay hydrated by drinking plenty of water as dehydration is often seen in cancers.

• Taking a stroll in the garden, or spending 30 mins of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired.

• Avoid tobacco use as smoking can increase the chances of lung cancer when used with Glocarbazin 50mg Tablet. Inform your doctor in case of marijuana use.

• Take Glocarbazin 50mg Tablet exactly as prescribed. 

• In case you miss a dose of Glocarbazin 50mg Tablet, take it as soon as possible. However, revert to the original schedule if it is too close to the next dose. Do not ever take a double dose.

• Please inform your doctor immediately if you accidentally take an extra dose of Glocarbazin 50mg Tablet. Some common symptoms of an overdose can be low blood pressure, slow pulse, shortness of breath, low blood sugar, fits, dizziness, feeling sick and discolouration of the skin.

•  Do not discontinue taking Glocarbazin 50mg Tablet abruptly or without the advice of the physician.

• Please know that your doctor may order blood tests to check your tolerance and need of Glocarbazin 50mg Tablet.

• Avoid getting out in the sun after taking Glocarbazin 50mg Tablet and if you do, make sure you use a potent sunscreen and wear protective clothing.

Hodgkin’s Disease: Hodgkin’s disease or lymphoma is a blood cancer of a certain type of cells called WBCs, specifically lymphocytes. Lymphocytes normally help control infection and maintain the body's normal immunity. However, in a cancerous state, there is an abnormal multiplication of these blood cells causing many problems such as fatigue, fever, loss of appetite, itching, night sweats and lymph node swelling.