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  3. Glypro 0.2 mg/ml Injection 1 ml

Glypro 0.2 mg/ml Injection 1 ml, Pack of 1
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Glypro 0.2 mg/ml Injection 1 ml contains glycopyrrolate, which works by inhibiting the action of acetylcholine. It is used to reduce secretions from the mouth, throat, or stomach (such as saliva or stomach acid), to avoid cardiac rhythm issues during anaesthesia, intubation, or surgery. Some of the common side effects include blurred vision, palpitations, urinary retention, and decreased sweating.

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Composition :

GLYCOPYRROLATE-0.2MG

Manufacturer/Marketer :

Jackson Laboratories Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Glypro 0.2 mg/ml Injection 1 ml

Glypro 0.2 mg/ml Injection 1 ml is used to reduce secretions from the mouth, throat, or stomach (such as saliva or stomach acid), to avoid cardiac rhythm issues during anesthesia, intubation, or surgery, or to minimize side effects from specific medications (such as pyridostigmine and neostigmine).

Glypro 0.2 mg/ml Injection 1 ml contains 'Glycopyrrolate', which works by inhibiting the action of acetylcholine. Thus, reduces gastric secretions' volume and free acidity and controls excessive pharyngeal, bronchial, and tracheal secretions.

Glypro 0.2 mg/ml Injection 1 ml will be administered by a healthcare professional; do not self-administer. In some cases, Glypro 0.2 mg/ml Injection 1 ml may cause dry mouth, urinary retention and hesitancy, blurred vision, palpitations, and decreased sweating. Most of these side effects of Glypro 0.2 mg/ml Injection 1 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Inform your doctor if you are allergic to any components in Glypro 0.2 mg/ml Injection 1 ml. Consult your doctor if you are pregnant or breastfeeding. Glypro 0.2 mg/ml Injection 1 ml may cause drowsiness and blurred vision, do not drive or operate machinery unless you are alert. Let your doctor know if you are taking prescription and non-prescription medications, including vitamins and herbal supplements.

Uses of Glypro 0.2 mg/ml Injection 1 ml

Glypro 0.2 mg/ml Injection 1 ml is used to treat various medical conditions. The detailed uses are as follows:

  • Reduction of preoperative secretions: It decreases saliva, tracheobronchial, and pharyngeal secretions to help maintain a clear airway during surgery.
  • Prevention and treatment of intraoperative bradycardia: It helps manage a slow heart rate during anaesthesia or surgical procedures.
  • Adjunct to anaesthesia: It minimises airway secretions and suppresses certain reflexes during anaesthesia, improving surgical safety and patient comfort.

Directions for Use

  • Glypro 0.2 mg/ml Injection 1 ml is administered by a qualified healthcare professional, typically in a hospital or clinic setting.
  • Your doctor will determine the appropriate dose and frequency based on your medical condition.
  • Follow your healthcare provider's instructions about the medication and any steps to track your progress or precautions during treatment.

Medicinal Benefits

  • Glypro 0.2 mg/ml Injection 1 ml contains Glycopyrrolate, which belongs to the group of medicines called anticholinergics.
  • Used during anaesthesia to reduce airway and gastric secretions, including the volume and acidity of gastric secretions.
  • Helps block cardiac inhibitory reflexes during induction of anaesthesia and intubation.
  • Used during surgery to manage arrhythmias caused by surgery, drugs, or vagal reflexes.
  • Protects against peripheral muscarinic effects of cholinergic agents.
  • Also used as adjunct therapy for treating peptic ulcers when an immediate anticholinergic effect is needed or when oral medication is not possible.
  • Works by inhibiting acetylcholine, thereby reducing gastric acidity and controlling excessive pharyngeal, bronchial, and tracheal secretions.

How Glypro 0.2 mg/ml Injection 1 ml Works

Glypro 0.2 mg/ml Injection 1 ml contains Glycopyrrolate, which works by blocking the action of acetylcholine, a chemical messenger involved in muscle contraction and secretion production. This action reduces the volume and acidity of gastric secretions and helps control excessive secretions in the mouth, throat, and airways, making it useful during surgery and certain medical conditions.

Storage

• Store in a cool and dry place away from sunlight.• Keep Glypro 0.2 mg/ml Injection 1 ml out of reach and sight of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Glypro 0.2 mg/ml Injection 1 ml

Glypro 0.2 mg/ml Injection 1 ml is a parenteral formulation, hence the chance of overdose may be less. However, keep a track of your medicine as an overdose of Glypro 0.2 mg/ml Injection 1 ml may cause serious side effects such as blurred vision. confusion, dizziness, faintness, etc. Reach the nearest hospital if you observe any of these side effects.

Drug Warnings

  • Inform your doctor if you are allergic to any medicines or foods.
  • Before receiving this injection, tell your doctor if you have any medical conditions such as glaucoma, bowel or bladder blockage, heart disease, irregular heartbeat, heart failure, high blood pressure, overactive thyroid, kidney or liver problems, muscle weakness, severe ulcerative colitis, toxic megacolon, or if you are very weak.
  • Let your doctor know if you are pregnant, planning to become pregnant, or breastfeeding.
  • Inform your doctor about all prescription and non-prescription medicines, vitamins, supplements, and herbal products you are taking to avoid interactions.
  • This medicine should be given only by a healthcare professional in a clinical setting where monitoring is available.

Drug-Drug Interactions

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GlycopyrrolatePotassium citrate
Critical
GlycopyrrolatePotassium chloride
Critical

Drug-Drug Interactions

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GlycopyrrolatePotassium citrate
Critical
How does the drug interact with Glypro 0.2 mg/ml Injection 1 ml:
Co-administration of Glypro 0.2 mg/ml Injection 1 ml with Potassium citrate can increase the risk or severity of ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
Taking Glypro 0.2 mg/ml Injection 1 ml with Potassium citrate together is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GlycopyrrolatePotassium chloride
Critical
How does the drug interact with Glypro 0.2 mg/ml Injection 1 ml:
Taking Glypro 0.2 mg/ml Injection 1 ml with Potassium chloride can increase the risk or severity of ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
Taking Glypro 0.2 mg/ml Injection 1 ml with Potassium chloride together is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GlycopyrrolateTopiramate
Severe
How does the drug interact with Glypro 0.2 mg/ml Injection 1 ml:
Coadministration of Glypro 0.2 mg/ml Injection 1 ml with Topiramate can increase the risk or severity of side effects like increased body temperature and decreased sweating.

How to manage the interaction:
Taking Glypro 0.2 mg/ml Injection 1 ml with Topiramate together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience drowsiness, dizziness, lightheadedness, fever, chills, or decreased sweating, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GlycopyrrolateZonisamide
Severe
How does the drug interact with Glypro 0.2 mg/ml Injection 1 ml:
Coadministration of Glypro 0.2 mg/ml Injection 1 ml with Zonisamide can increase the risk or severity of Zonisamide side effects like increased body temperature and decreased sweating especially in warm weather.

How to manage the interaction:
Taking Glypro 0.2 mg/ml Injection 1 ml with Zonisamide together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience dizziness, drowsiness, fatigue, increased heart rate, fever, or excessive sweating, contact a doctor immediately. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting a doctor.
GlycopyrrolateTirzepatide
Moderate
How does the drug interact with Glypro 0.2 mg/ml Injection 1 ml:
Tirzepatide may raise heart rate and may interact with other drugs that raise heart rate, like Glypro 0.2 mg/ml Injection 1 ml, to have additive effects.

How to manage the interaction:
If you discover that your heart rate is elevated at other times for no apparent cause, or if it is happening frequently, you should speak with your doctor. Chest pain, shortness of breath, and the feeling of a pounding or racing heartbeat are all indications of an increased heart rate.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Peptic ulcers:
  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight through regular exercise.
  • Avoid lying down after eating to prevent acid reflux.
  • Avoid tight-fitting clothes as they might increase the pressure on the abdomen, leading to acid reflux.
  • Practice relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat, spicy, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea, and soda.
  • Avoid sitting continuously, as it may trigger acidity. Take a break of 5 minutes every hour by brisk walking or stretching.

Habit Forming

No

Therapeutic Class

ANTICHOLINERGICS

Glypro 0.2 mg/ml Injection 1 ml Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

It is best to avoid alcohol while taking Glypro 0.2 mg/ml Injection 1 ml, as it can increase side effects like drowsiness, dizziness, blurred vision, and dry mouth. Combining the two may also impair judgment and coordination. Speak to your doctor if you have any concerns regarding this.

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Pregnancy

Caution

Inform your doctor if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Inform your doctor if you are breastfeeding; your doctor will decide whether Glypro 0.2 mg/ml Injection 1 ml can be given to breastfeeding mothers or not.

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Driving

Caution

Glypro 0.2 mg/ml Injection 1 ml may cause drowsiness and blurred vision. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Please inform your doctor if you have liver problems or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Please inform your doctor if you have kidney problems.

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Children

Caution

Glypro 0.2 mg/ml Injection 1 ml is generally not recommended for children unless prescribed by a doctor. Safety and effectiveness can vary with age, and the dose must be carefully adjusted by a healthcare professional based on medical need. Always follow your doctor’s advice before giving this medicine to a child.

Have a query?

FAQs

Glypro 0.2 mg/ml Injection 1 ml is used to reduce secretions from the mouth, throat, or stomach (such as saliva or stomach acid), to avoid cardiac rhythm issues during anesthesia, intubation, or surgery, or to minimize side effects from specific medications (such as pyridostigmine and neostigmine).

Dry mouth could be a side effect of Glypro 0.2 mg/ml Injection 1 ml. Limiting caffeine intake, avoiding smoking, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva, thereby preventing drying of the mouth.

Glypro 0.2 mg/ml Injection 1 ml may cause heat prostration (overheating of the body due to severe weather conditions). You are advised to avoid high environmental temperatures.

Glypro 0.2 mg/ml Injection 1 ml may cause mydriasis (pupil dilation) and increased intraocular pressure in patients with glaucoma. Inform your doctor if you have glaucoma or ocular hypertension.

Glypro 0.2 mg/ml Injection 1 ml may cause tachycardia (increased heart rate). Inform your doctor if you have heart rate problems. Glypro 0.2 mg/ml Injection 1 ml should be used with caution in patients with cardiac arrhythmia, congestive heart failure, coronary artery disease, high blood pressure, and hyperthyroidism.

Glypro 0.2 mg/ml Injection 1 ml works by inhibiting the action of acetylcholine. Thus, it reduces the volume and free acidity of gastric secretions and controls excessive pharyngeal, bronchial, and tracheal secretions.

Country of origin

India

Manufacturer/Marketer address

Jackson Laboratories Private Limited, Majitha Road Bypass, Amritsar-143004, Punjab, India
Other Info - GLY0775

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 8, 2025 | 12:08 PM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/210997s000lbl.pdf
  2. https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=62267afe-1a73-4623-984e-646db590ec5b&type=display
  3. https://pdf.hres.ca/dpd_pm/00044183.PDF

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