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compositionComposition:CEFIXIME-50MG+CLAVULANIC ACID-31.25MG
prescription
Prescription Medicine
info
Grandclav Dry Syrup
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CEFIXIME-50MG+CLAVULANIC ACID-31.25MG

Manufacturer/Marketer :

Ronyd Healthcare Pvt Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Grandclav Dry Syrup

Grandclav Dry Syrup is a prescription oral combination antibiotic used to treat a wide variety of bacterial infections. It is commonly prescribed to treat infections of the lungs, airways, urinary tract, ears, and throat. By targetting the bacteria causing your illness, this medication clears the infection and supports your body's recovery.

To get the best results, you must take Grandclav Dry Syrup consistently at the same times each day as directed by your doctor. It can be taken with or without food, though taking your dose with a meal can help prevent a mild upset stomach. Adopting supportive lifestyle habits, such as staying well-hydrated and prioritising quality rest, will also help your body heal more quickly.

While taking Grandclav Dry Syrup, you may experience mild side effects such as loose stools, nausea, or stomach discomfort. However, if you develop severe watery diarrhoea, a skin rash, swelling, or difficulty breathing, you must stop taking the medicine and seek immediate medical attention. Always consult your doctor if you experience any unusual or persistent symptoms.

Before starting this medication, tell your healthcare provider if you have a history of kidney disease, liver problems, or severe allergies. You should not take this medicine if you have previously had a severe allergic reaction to cefixime, other cephalosporin antibiotics, or any component of the formulation. Cefixime is a cephalosporin antibiotic, not a penicillin. Although cross-reactivity between penicillins and cephalosporins can occur, the overall risk is generally considered low (approximately 1–2%). Your doctor will help determine whether this medicine is appropriate based on your allergy history.

This medicine can interact with blood thinners, certain gout medications, and live vaccines, which may alter how it works or increase your risk of side effects. Alcohol does not have a major direct interaction with this medicine, but it may worsen stomach irritation, nausea, or dehydration in some individuals. Limiting alcohol intake during treatment may help improve comfort and recovery. If you are pregnant, breastfeeding, or managing health conditions in your elderly years, consult your doctor before starting Grandclav Dry Syrup.

Uses of Grandclav Dry Syrup

Grandclav Dry Syrup is used to treat a wide variety of bacterial infections. The detailed uses of Grandclav Dry Syrup are as follows:

  • Respiratory Tract Infections: Grandclav Dry Syrup clears bacterial infections in the lungs and airways, such as bacterial bronchitis and pneumonia, by stopping bacterial growth. Most cases of bronchitis are caused by viruses and do not require antibiotics, so this medicine should only be used when a bacterial infection is suspected or confirmed by a doctor.
  • Urinary Tract Infections (UTIs): It targets and eliminates the bacteria responsible for painful infections in the bladder and kidneys.
  • Ear, Nose, and Throat Infections: This medicine helps resolve painful middle ear infections, severe sinus infections, and tonsillitis.
  • Typhoid Fever: In certain cases, doctors prescribe Grandclav Dry Syrup to treat typhoid fever by clearing the systemic bacterial infection.

 

Key Benefits

The primary benefit of Grandclav Dry Syrup is its ability to successfully treat infections that might otherwise resist standard antibiotics. By combining two active components, this medicine ensures a more reliable and complete recovery.

  • Overcomes Bacterial Resistance: It remains highly effective even against difficult bacterial strains that have developed defences against older antibiotics.
  • Faster Symptom Relief: By rapidly stopping the spread of bacteria, it helps reduce fever, pain, and discomfort within a few days of starting treatment.
  • Prevents Infection Spread: Clearing the bacteria quickly prevents the infection from travelling to other parts of your body or worsening.
     
Side effects of Grandclav Dry Syrup
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Avoid trigger foods that can cause allergic reactions, such as nuts, shellfish, or dairy products.
  • Keep a food diary to track potential food allergens.
  • Include omega-3 rich foods like salmon and walnuts to reduce inflammation.
  • Wear loose, comfortable clothing made from soft fabrics like cotton.
  • Apply cool compresses or take cool baths to reduce itching.
  • Use gentle soaps and avoid harsh skin products.
  • Reduce stress through relaxation techniques like meditation or deep breathing.
Here are the steps to manage angioedema (Swelling Under The Skin) as a side effect of medication:
  • If you experience angioedema, inform your doctor immediately. Treatment can help keep the swelling under control.
  • Seek medical attention if symptoms are severe, such as difficulty breathing or swallowing.
  • Follow your doctor's instructions to manage symptoms, which may include stopping or adjusting the medication that triggered angioedema.
  • Your doctor may also recommend antihistamines, steroids, or other treatments to reduce swelling and inflammation.
  • Make dietary and lifestyle changes as recommended, such as avoiding trigger foods or reducing stress.
  • Monitor your condition closely and track your symptoms to report them to your doctor.
  • Consult your doctor again if symptoms worsen or do not improve or if you experience any new or concerning symptoms.
  • Let your doctor know if there are unsual symptoms after taking the medication, such as red patches on your skin.
  • Your doctor may change your medication, lower the dose, or stop the treatment to help manage the symptoms.
  • Avoid heavy physical activity and get plenty of rest to prevent further worsening of the symptoms.
  • Apply cold packs to the affected areas for relief.
  • Keep yourself hydrated or take supplements to get enough vitamins.
  • Over-the-counter pain relievers can help with discomfort.
  • Changes in kidney function need immediate medical attention.
  • Always monitor your blood pressure and inform your healthcare team if there are any sudden changes.
  • Take medicines as prescribed and eat a balanced diet suggested by your dietician for healthy kidney function.
  • Physical activity and exercise must be included in your daily routine to have proper kidney functioning and to maintain a healthy weight.
  • Get enough sleep to reduce the stress levels that have a direct impact on your kidney functioning.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Directions for Use

Follow these guidelines to ensure you take Grandclav Dry Syrup safely and effectively:

  • Take it by mouth: Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet unless your doctor tells you to.
  • Measure liquid doses carefully: If you are taking the liquid suspension form, always use the provided measuring syringe or cup to get the exact dose. Shake the bottle well before each use.
  • Keep a consistent schedule: Take your doses at evenly spaced intervals throughout the day to keep a constant level of medicine in your body.
  • Finish the entire course: Even if you start feeling better within a few days, continue taking the medication until the full prescribed course is finished. Stopping early can allow the remaining bacteria to multiply and become resistant to future treatments.
  • Always follow your doctor's exact instructions regarding your specific dose and duration of treatment.
     

How Grandclav Dry Syrup Works

To understand how Grandclav Dry Syrup works, it helps to look at its two active ingredients and how they cooperate in your body. The primary antibiotic ingredient targets the bacteria directly. It works by interfering with the construction of the bacterial cell wall, which is essential for the bacteria's survival. Without a strong wall, the bacteria burst and die. This action stops the spread of the infection and allows your immune system to clear the remaining bacteria. However, some bacteria produce defensive enzymes called beta-lactamases that can destroy antibiotics before they can work. This is where the second protective ingredient comes in. It acts as a shield, binding to and disabling these destructive enzymes. This protective action allows the primary antibiotic to do its job uninterrupted, ensuring the infection is wiped out effectively.
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Alcohol

Caution

Avoid consuming alcohol while taking Grandclav Dry Syrup to prevent unpleasant side-effects.

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Pregnancy

Caution

Please consult your doctor if you are pregnant, your doctor will prescribe Grandclav Dry Syrup only if the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult your doctor if you are breastfeeding, your doctor will prescribe Grandclav Dry Syrup only if the benefits outweigh the risks.

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Driving

Caution

Grandclav Dry Syrup may cause confusion, decreased alertness, and unusual muscle stiffness or movements. Do not drive or operate machinery if you experience these symptoms.

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Liver

Caution

Please consult your doctor before taking Grandclav Dry Syrup if you have liver impairment/liver disease before taking Grandclav Dry Syrup.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease before taking Grandclav Dry Syrup.

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Children

Safe if prescribed

Grandclav Dry Syrup is safe for children if prescribed by a doctor. The dose and duration may vary depending upon age and severity of the infection.

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Heart

Consult your doctor

Caution should be exercised while taking Grandclav Dry Syrup in patients with heart disease. Inform your physician on priority if you/your child have chest discomfort, palpitations or irregular heartbeat. Your physician may adjust the dose of the medicine based on your health condition.

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Geriatrics

Safe if prescribed

Grandclav Dry Syrup is safe for use in geriatric patients if recommended by the physician. Your doctor will decide the dose and duration of medicine.<br />

What if I have taken an overdose of Grandclav Dry Syrup

Do not take more than the prescribed dose of Grandclav Dry Syrup as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Support your gut health: Antibiotics can disrupt your natural gut bacteria. Consider eating probiotic-rich foods like yoghurt, kefir, or fermented vegetables a few hours after taking your dose to help maintain a healthy gut balance.
  • Stay hydrated: Drink plenty of water throughout the day, especially if you experience mild diarrhoea or loose stools, to prevent dehydration.
  • Rest up: Give your body the energy it needs to fight the infection by getting plenty of quality sleep and avoiding strenuous physical activity.
  • Avoid stomach irritants: Steer clear of highly spicy, greasy, or acidic foods while on this medication to minimise the risk of nausea and stomach upset.
     

Have a query?

How Soon It Starts Working

The time required for Grandclav Dry Syrup to start to work: Grandclav Dry Syrup ideally shows its action within 2 to 4 hours after administration. The time for which the effects of Grandclav Dry Syrup last: The duration of action for Grandclav Dry Syrup is unknown.

What if you forget to take Grandclav Dry Syrup

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next dose at the scheduled time. Do not take a double dose.

Storage

•Store the tablets at room temperature, ideally between 20°C and 25°C (68°F to 77°F) •Keep them in their original packaging to protect them from light and moisture. Do not store them in the bathroom.

Drug Warnings

  • Inspect the liquid: If using the suspension, check the colour and consistency before each use. Shake well, and do not use if it looks discoloured or contains unusual clumps.
  • Complete the full course: Never stop taking Grandclav Dry Syrup early just because your symptoms disappear; doing so increases the risk of the infection returning stronger and resistant to treatments.
  • Hormonal contraception: Current evidence does not suggest that routine use of additional contraception is required for most people taking cefixime-containing antibiotics. However, if you experience severe diarrhoea or vomiting, contraceptive absorption may be affected. Consult your doctor or pharmacist if you have concerns about contraception while taking this medicine.
  • Watch for signs of thrush: Prolonged use of antibiotics can cause oral thrush or vaginal yeast infections. Contact your doctor if you notice white patches in your mouth or unusual discharge.
  • Inform other healthcare providers: Always let dentists, surgeons, or lab technicians know you are taking Grandclav Dry Syrup, as it can occasionally interfere with certain medical tests (like urine sugar tests).
     

Drug-Drug Interactions

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Drug-Drug Interactions

  • Blood Thinners (e.g., Warfarin): Combining Grandclav Dry Syrup with blood thinners may increase the risk of bleeding. Your doctor may need to monitor your blood clotting times more closely.
  • Gout Medications (e.g., Probenecid): Taking these together can increase the level of the antibiotic in your blood, making side effects more likely.
  • Live Vaccines (e.g., Oral Typhoid Vaccine): This antibiotic can stop live bacterial vaccines from working properly. It is best to delay vaccines until your treatment is complete.

Drug-Food Interactions

  • Dairy and Calcium: While you can take this medication with food, consuming very large amounts of dairy products simultaneously might slightly affect absorption. Normal dietary amounts are generally fine.

Drug-Disease Interactions

  • Kidney Disease: If your kidneys are not working fully, this medication can build up in your body, meaning your doctor may need to adjust your dose.
  • Colitis or Gastrointestinal Disease: If you have a history of severe bowel inflammation, this medication can trigger severe diarrhoea flare-ups.
  • History of Penicillin or Cephalosporin Allergy: Patients with a history of severe allergic reactions to cephalosporins should generally avoid Grandclav Dry Syrup. Individuals with a penicillin allergy may have a small risk of cross-reactivity with cephalosporins, so a careful medical history should be reviewed before treatment. 
     
Cefixime + Clavulanic acidCholera, live attenuated
Severe
Cefixime + Clavulanic acidBCG vaccine
Severe

Drug-Drug Interactions

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Cefixime + Clavulanic acidCholera, live attenuated
Severe
How does the drug interact with Grandclav Dry Syrup:
Co-administration of Cefixime with Cholera vaccine may reduce the effectiveness of the vaccine.

How to manage the interaction:
Talk to your doctor before receiving the cholera vaccine if you are currently being treated with cefixime or have been treated within the last 14 days. To ensure adequate vaccine response, you should not receive cholera vaccine until at least 14 days after you complete your antibiotic therapy. Do not discontinue the medication without consulting a doctor.
Cefixime + Clavulanic acidBCG vaccine
Severe
How does the drug interact with Grandclav Dry Syrup:
Taking cefixime and the BCG vaccine together can reduce the anti-tumor activity of BCG in the bladder.

How to manage the interaction:
Talk to your doctor before receiving the BCG vaccine. To ensure an adequate vaccine response, you should not receive BCG vaccine until after you complete your antibiotic therapy. Do not discontinue the medication without consulting a doctor.
Cefixime + Clavulanic acidMycophenolic acid
Severe
How does the drug interact with Grandclav Dry Syrup:
Taking cefixime and mycophenolic acid together can reduce the blood levels and effects of mycophenolic acid.

How to manage the interaction:
Using cefixime and mycophenolic acid together can lead to an interaction; it can be taken if your doctor has suggested it. If you experience any symptoms like less urine output, shortness of breath, swelling, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Grandclav Dry Syrup is used to treat various bacterial infections of the urinary tract, ear, throat, lungs, and uncomplicated gonorrhoea.

Grandclav Dry Syrup is a combination of two antibiotics, namely: Cefixime (cephalosporin antibiotic) and Clavulanic acid (beta-lactamase inhibitor). Cefixime works by preventing the formation of bacterial cell covering, which is necessary for their survival, thereby, killing the bacteria, preventing the spread of infections. Clavulanic acid works by enhancing the activity of cefixime against bacteria and decreases bacterial resistance.

Do not take Grandclav Dry Syrup if you are pregnant or planning for pregnancy unless prescribed by a doctor. Your doctor will prescribe Grandclav Dry Syrup only if the benefits outweigh the risks.

It is safe to give Grandclav Dry Syrup to a child if prescribed by the doctor. The dose and duration may vary depending upon the age and severity of the infection.

Do not take Grandclav Dry Syrup on your own as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections.

Grandclav Dry Syrup may affect certain laboratory test results such as blood tests, glucose test, and coombs test. Inform the person doing the tests that you are taking Grandclav Dry Syrup. Your doctor might ask you to stop the intake of Grandclav Dry Syrup before conducting these tests.

Current evidence does not suggest that cefixime significantly reduces the effectiveness of most hormonal contraceptives. However, severe diarrhoea or vomiting while taking Grandclav Dry Syrup may reduce the absorption of oral contraceptives. If this occurs, follow the instructions provided with your contraceptive product and consult your doctor or pharmacist for advice.

You should take Grandclav Dry Syrup for the full duration prescribed by your doctor, even if you start feeling better before completing the course. Stopping treatment too early may allow the infection to return and can contribute to antibiotic resistance. Do not stop taking Grandclav Dry Syrup without consulting your doctor.

No. Grandclav Dry Syrup is an antibiotic that works only against bacterial infections. It is not effective against viral infections such as the common cold or flu. Using antibiotics unnecessarily may contribute to antibiotic resistance

It is advisable to avoid alcohol while taking Grandclav Dry Syrup. Alcohol may worsen stomach-related side effects such as nausea, vomiting, and indigestion and may contribute to dehydration. Consult your doctor if you have questions about alcohol use during treatment.

Swallow the medicine as a whole with a glass of water; do not chew or crush. Follow your doctor's dosage and duration instructions.

If you have Renal problems, use Grandclav Dry Syrup with caution. Your doctor may need to adjust the dose if you are based on your renal impairment. Always consult your healthcare provider for specific guidance on using Grandclav Dry Syrup with renal impairment.

When taking Grandclav Dry Syrup, follow these precautions: take the medication as directed, inform your doctor about allergies, kidney/liver issues, and other medications. Avoid excessive alcohol, be cautious while driving, and monitor blood clotting if taking anticoagulants. Pregnant or breastfeeding women should consult their doctor before taking. Complete the full course to prevent antibiotic resistance and watch for signs of allergy, diarrhea, or liver damage. Store them safely and consult your doctor/pharmacist for personalized guidance if necessary.

In rare cases, Grandclav Dry Syrup may cause serious side effects such as severe allergic reactions (rash, itching), kidney issues, severe stomach pain, diarrhea that is watery, jaundice, seizure, and low blood cell counts. If you are experiencing any of these effects, please consult your physician immediately. Your doctor will suggest the best way to overcome these events.

Before using this medication, you should inform your doctor about your medical history, including any ongoing medicines, to avoid potential interactions and minimise side effects.

If you don't feel better after completing Grandclav Dry Syrup, consult the doctor. The infection may not be responding due to incorrect diagnosis, antibiotic resistance, or underlying conditions. The doctor will reassess, possibly conduct tests, and adjust treatment. Don't self-medicate or repeat the course without consulting your doctor, as this risks antibiotic resistance and side effects.

Store Grandclav Dry Syrup its original container, keeping it cool, dry, and out of sunlight. Make sure it's out of reach of children. Regularly check the expiration date. When you need to dispose of the medicine, remove the label, place it in a plastic bag, and throw it away in the household trash. Remember, never flush the medicine down the toilet or sink to prevent harm to others and the environment.

If you miss a dose of Grandclav Dry Syrup, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to complications.

When taking Grandclav Dry Syrup, be cautious with antacids. Only take antacids if your doctor advises it, and timing is crucial. Take antacids at least two hours before or four hours after taking Grandclav Dry Syrup to avoid any interactions. This will help ensure your safety and the effectiveness of your medication. Always consult your doctor for personalized guidance.

The most common side effects of Grandclav Dry Syrup, including diarrhea, nausea, vomiting, stomach pain, indigestion, bloating, flatulence, headache, dizziness, and weakness. These side effects are usually mild and temporary, resolving as your body adjusts to the medication. However, if any side effects persist or worsen, it's essential to consult your doctor for proper guidance and care.

Diarrhoea may occur as a side effect of Grandclav Dry Syrup. Drink plenty of fluids to stay hydrated. However, if you develop severe, persistent, watery, or bloody diarrhoea, especially with stomach cramps, stop taking the medicine and contact your doctor immediately. Do not take anti-diarrhoeal medicines without medical advice.

Yes, you can take Grandclav Dry Syrup with or without food. However, if you find that it causes stomach discomfort or mild nausea, taking it with a meal or a small snack can help settle your stomach. Talk to your doctor or pharmacist if stomach issues persist.

Grandclav Dry Syrup begins working soon after you start taking it, although symptom improvement is usually noticed within 24–48 hours. Recovery time varies depending on the type and severity of the infection and your individual response to treatment. Continue taking the medicine for the full prescribed course even if you start feeling bet

If you have had a severe allergic reaction (such as hives, swelling, or breathing issues) to penicillin, you may also be allergic to Grandclav Dry Syrup. You must inform your healthcare provider about any antibiotic allergies before starting this medication. Talk to your doctor to find a safe alternative.

Once mixed by your pharmacist, the liquid suspension form of Grandclav Dry Syrup must be kept in the refrigerator, ideally between 2°C and 8°C, and should never be frozen. Any unused liquid must be thrown away after 10 to 14 days. Talk to your doctor or pharmacist if you are unsure how to store your specific prescription.

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Country of origin

India

Manufacturer/Marketer address

A/707, Signature II, Near Sarkhej Sanand Cross Road, Sarkhej 382210 Ahmedabad gujarat
Other Info - GR39434
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