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GRANDEM 1MG INJECTION 1ML

Manufacturer/Marketer

ARI-ARISTO PHARMACEUTICALS

Consume Type

PARENTERAL

In Stock

Prescription Required
Product Details

About GRANDEM 1MG INJECTION 1ML

GRANDEM 1MG INJECTION 1ML belongs to the class of 'anti-emetic' drugs, primarily used to treat nausea and vomiting caused by medical treatments after surgery or chemotherapy or radiation treatment for cancer. Nausea is defined as stomach discomfort and the sensation of an urge to vomit. Vomiting is the forcible voluntary or involuntary emptying of contents of the stomach through the mouth.

GRANDEM 1MG INJECTION 1ML contains an anti-emetic (eases vomiting symptoms) medicine, 'Granisetron', that belongs to the class of 5-HT3 receptor antagonists (also called serotonin receptor antagonists or serotonin blockers). It works by blocking the brain's serotonin (chemical messenger) activity that triggers nausea and vomiting during cancer treatment (chemotherapy or radiation therapy) or after surgery.

GRANDEM 1MG INJECTION 1ML will be administered by a healthcare professional; do not self-administer. Your doctor will decide the dose and duration based on the severity of your medical condition. Common side effects of GRANDEM 1MG INJECTION 1ML include diarrhoea, constipation, stomach pain, weakness, headache, fever, drowsiness, trouble sleeping, pain, redness, and swelling at the injection site. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

If you use other prescription or non-prescription medicines, inform your doctor before using GRANDEM 1MG INJECTION 1ML. Let your doctor know if you have any liver, kidney or heart diseases, stomach/intestinal problems, allergic reactions, and low levels of potassium and magnesium in the blood before starting GRANDEM 1MG INJECTION 1ML. This medicine may make you dizzy or drowsy; hence avoid driving or operating machinery if you are not mentally alert. Consult your doctor before using GRANDEM 1MG INJECTION 1ML if you are pregnant, planning for pregnancy or breastfeeding. Avoid consuming alcohol while being treated with GRANDEM 1MG INJECTION 1ML as it could lead to unwanted side effects. 

Uses of GRANDEM 1MG INJECTION 1ML

Nausea and vomiting.

Medicinal Benefits

GRANDEM 1MG INJECTION 1ML contains an anti-emetic medicine, 'Granisetron', that treats nausea and vomiting caused due to cancer treatment (chemotherapy or radiation therapy) or after surgery. Granisetron belongs to the class of 5-HT3 receptor antagonists (also called serotonin receptor antagonists or serotonin blockers). When the cells lining the gastrointestinal tract are damaged by chemotherapy or radiation therapy, they release a natural substance called serotonin (5HT3, 5-hydroxytryptamine). This serotonin binds to serotonin receptors on nerves that induces nausea and vomiting. GRANDEM 1MG INJECTION 1ML works by blocking the brain's serotonin activity and preventing postoperative nausea and vomiting. 

Directions for Use

It will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of GRANDEM 1MG INJECTION 1ML

  • Diarrhoea
  • Constipation
  • Stomach pain
  • Weakness
  • Headache
  • Fever
  • Dizziness
  • Drowsiness
  • Trouble sleeping
  • Pain, redness, and swelling at the injection site

In-Depth Precautions and Warning

Drug Warnings

Seeking medical advice if you use prescription or non-prescription medicines while being treated with GRANDEM 1MG INJECTION 1ML is suggested. Inform your doctor about a history of stomach/intestinal problems, heart diseases, electrolyte imbalance (potassium, sodium or calcium), and liver or kidney diseases before starting GRANDEM 1MG INJECTION 1ML. Please consult your doctor if you are pregnant or breastfeeding if the doctor advised you GRANDEM 1MG INJECTION 1ML. This medicine may make you feel dizzy, so drive or operate machinery only if you are alert. Avoid consuming alcohol during the course, as it could lead to increased dizziness. GRANDEM 1MG INJECTION 1ML is not recommended in children below two years of age.

Drug Interactions

Drug-Drug Interaction: GRANDEM 1MG INJECTION 1ML may interact with antidepressants (fluoxetine, duloxetine), heart-related drugs (amiodarone, sotalol), antipsychotic drugs (pimozide), antibiotics (erythromycin), and St. John's wort, a plant-based medicine used for depression and mood disorders.

Drug-Food Interaction: Alcohol may increase dizziness when taken with GRANDEM 1MG INJECTION 1ML.

Drug-Disease Interaction: Before using GRANDEM 1MG INJECTION 1ML, let your doctor know if you have any stomach/intestinal problems like stomach ache, wind, feeling or being sick, difficulty passing stools, electrolyte imbalance (potassium, sodium or calcium), heart problems, liver or kidney diseases.

Drug-Drug Interactions Checker List:

  • FLUOXETINE
  • DULOXETINE
  • AMIODARONE
  • SOTALOL
  • PIMOZIDE
  • ERYTHROMYCIN
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      You are recommended to limit or avoid alcohol consumption while taking GRANDEM 1MG INJECTION 1ML. Alcohol intake, along with GRANDEM 1MG INJECTION 1ML, may lead to unwanted side effects and cause increased dizziness.

    • Safety Warning

      Pregnancy

      caution

      It is not known if GRANDEM 1MG INJECTION 1ML affects pregnancy. Please inform your doctor if you are pregnant or planning pregnancy before receiving GRANDEM 1MG INJECTION 1ML.

    • Safety Warning

      Breast Feeding

      caution

      It is not known if this medicine passes into breast milk. Please inform your doctor before taking GRANDEM 1MG INJECTION 1ML if you are a nursing mother.

    • Safety Warning

      Driving

      caution

      GRANDEM 1MG INJECTION 1ML may make you feel dizzy, affecting your mental ability. Do not drive or operate machinery if you experience dizziness.

    • Safety Warning

      Liver

      caution

      GRANDEM 1MG INJECTION 1ML should be used with caution if you have liver disease. Please inform your doctor if you have a history of liver impairment before starting GRANDEM 1MG INJECTION 1ML.

    • Safety Warning

      Kidney

      caution

      GRANDEM 1MG INJECTION 1ML should be used with caution if you have kidney problems. Please inform your doctor if you have a history of kidney impairment/kidney disease.

    • Safety Warning

      Children

      caution

      Safety and efficacy of GRANDEM 1MG INJECTION 1ML have not been established in children below 2 years of age.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Avoid chocolates, junk food, cheese, processed food, alcohol, and smoking. 
    • You can try increasing your mindfulness by doing yoga, meditation, mindfulness-based cognitive therapy, and stress reduction techniques.
    • Drink enough water to stay hydrated and limit or avoid alcohol and caffeine.
    • Include a diet rich in whole grains, vegetables, and fruits.
    • You can include antioxidants in your daily diet, like ashwagandha, omega-3 fatty acids, green tea, and lemon.
    • Try to spend time with your friends and family. Having a strong social network may help you lower your risk of anxiety.

    Special Advise

    • Let your doctor know you are taking GRANDEM 1MG INJECTION 1ML if you undergo medical tests.
    • Heart function monitoring with an ECG or EKG (electrocardiogram) is recommended in heart patients since GRANDEM 1MG INJECTION 1ML may cause irregular heartbeat and QT prolongation (heart muscle takes longer than normal to recharge between beats).

    Other Information (GRA0008)

    This item is Not Returnable.

    Expires on or after - Sep-23

    Patients Concern

    Disease/Condition Glossary

    Nausea is defined as stomach discomfort and the sensation of an urge to vomit. It is a precursor to vomiting. It is not a painful symptom but can cause discomfort in the chest, upper abdomen, or back of the throat. Nausea can be triggered by various factors like motion from a car and plane, taking pills on an empty stomach, eating too much or too little, and drinking excessive amounts of alcohol. 

    Vomiting or throwing up is the forcible voluntary or involuntary emptying of contents of the stomach through the mouth. Vomiting can also occur without any underlying diseases like pregnancy, hangovers, overeating, and motion sickness. Nausea or vomiting may be triggered by many factors, including food poisoning, gastritis (inflammation of the stomach lining), an ulcer, or bulimia (eating disorder).

    FAQs

    GRANDEM 1MG INJECTION 1ML contains Granisetron, an anti-emetic drug. It is a serotonin blocker that blocks the activity of serotonin, a chemical messenger that induces nausea and vomiting after treatments like chemotherapy and radiation therapy. Thus, GRANDEM 1MG INJECTION 1ML relieves post-operative nausea and vomiting symptoms.

    GRANDEM 1MG INJECTION 1ML may cause constipation as one of its side effects. You can avoid it by including high-fibre food in your diet that improves your digestion. Limit the intake of alcohol to manage your constipation.

    GRANDEM 1MG INJECTION 1ML should be used with caution if you have recent stomach/intestinal problems like stomach ache, wind, feeling or being sick, difficulty passing stools, heart rhythm disorder, a recent stomach or intestinal surgery, electrolyte imbalance (potassium, sodium or calcium), and liver or kidney diseases.

    You are advised to complete the course prescribed by your doctor. Please do not stop taking this medicine unless advised by your doctor since it may lead to recurrent episodes of nausea and vomiting.

    PRODUCT SUBSTITUTES

    GRANDEM 1MG INJECTION 1ML

    Country Of Origin

    India

    Manufacturer/Marketer address

    Mercantile Chamber, 3rd Floor, 12, J.N. Heredia Marg, Ballard Estate, Mumbai – 400 001, India.

    Disclaimer

    While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

    (Inclusive of all taxes)

    Provide Delivery Location

    Vial

    1

    1 ml Injection in 1 Vial