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Grandem 1 mg Injection 3 ml belongs to the class of 'anti-emetic' drugs, primarily used to treat nausea and vomiting caused by medical treatments after surgery or chemotherapy or radiation treatment for cancer. Nausea is defined as stomach discomfort and the sensation of an urge to vomit. Vomiting is the forcible voluntary or involuntary emptying of contents of the stomach through the mouth.
Grandem 1 mg Injection 3 ml contains an anti-emetic (eases vomiting symptoms) medicine, 'Granisetron', that belongs to the class of 5-HT3 receptor antagonists (also called serotonin receptor antagonists or serotonin blockers). It works by blocking the brain's serotonin (chemical messenger) activity that triggers nausea and vomiting during cancer treatment (chemotherapy or radiation therapy) or after surgery.
Grandem 1 mg Injection 3 ml will be administered by a healthcare professional; do not self-administer. Your doctor will decide the dose and duration based on the severity of your medical condition. Common side effects of Grandem 1 mg Injection 3 ml include diarrhoea, constipation, stomach pain, weakness, headache, fever, drowsiness, trouble sleeping, pain, redness, and swelling at the injection site. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.
If you use other prescription or non-prescription medicines, inform your doctor before using Grandem 1 mg Injection 3 ml. Let your doctor know if you have any liver, kidney or heart diseases, stomach/intestinal problems, allergic reactions, and low levels of potassium and magnesium in the blood before starting Grandem 1 mg Injection 3 ml. This medicine may make you dizzy or drowsy; hence avoid driving or operating machinery if you are not mentally alert. Consult your doctor before using Grandem 1 mg Injection 3 ml if you are pregnant, planning for pregnancy or breastfeeding. Avoid consuming alcohol while being treated with Grandem 1 mg Injection 3 ml as it could lead to unwanted side effects.
Grandem 1 mg Injection 3 ml is used in the treatment of Nausea and vomiting. The detailed uses of Grandem 1 mg Injection 3 ml are as follows:
Grandem 1 mg Injection 3 ml contains an anti-emetic medicine, 'Granisetron', that treats nausea and vomiting caused due to cancer treatment (chemotherapy or radiation therapy) or after surgery. Granisetron belongs to the class of 5-HT3 receptor antagonists (also called serotonin receptor antagonists or serotonin blockers). When the cells lining the gastrointestinal tract are damaged by chemotherapy or radiation therapy, they release a natural substance called serotonin (5HT3, 5-hydroxytryptamine). This serotonin binds to serotonin receptors on nerves that induces nausea and vomiting. Grandem 1 mg Injection 3 ml works by blocking the brain's serotonin activity and preventing postoperative nausea and vomiting.
Caution
You are recommended to limit or avoid alcohol consumption while taking Grandem 1 mg Injection 3 ml. Alcohol intake, along with Grandem 1 mg Injection 3 ml, may lead to unwanted side effects and cause increased dizziness.
Caution
It is not known if Grandem 1 mg Injection 3 ml affects pregnancy. Please inform your doctor if you are pregnant or planning pregnancy before receiving Grandem 1 mg Injection 3 ml.
Caution
It is not known if this medicine passes into breast milk. Please inform your doctor before taking Grandem 1 mg Injection 3 ml if you are a nursing mother.
Caution
Grandem 1 mg Injection 3 ml may make you feel dizzy, affecting your mental ability. Do not drive or operate machinery if you experience dizziness.
Caution
Grandem 1 mg Injection 3 ml should be used with caution if you have liver disease. Please inform your doctor if you have a history of liver impairment before starting Grandem 1 mg Injection 3 ml.
Caution
Grandem 1 mg Injection 3 ml should be used with caution if you have kidney problems. Please inform your doctor if you have a history of kidney impairment/kidney disease.
Caution
Safety and efficacy of Grandem 1 mg Injection 3 ml have not been established in children below 2 years of age.
Consult your doctor
Please consult your doctor if you have any pre-existing heart disease before using Grandem 1 mg Injection 3 ml.
Consult your doctor
Limited information available about the use of Grandem 1 mg Injection 3 ml in geriatric patients. Please consult your physician.
Have a query?
Seeking medical advice if you use prescription or non-prescription medicines while being treated with Grandem 1 mg Injection 3 ml is suggested. Inform your doctor about a history of stomach/intestinal problems, heart diseases, electrolyte imbalance (potassium, sodium or calcium), and liver or kidney diseases before starting Grandem 1 mg Injection 3 ml. Please consult your doctor if you are pregnant or breastfeeding if the doctor advised you Grandem 1 mg Injection 3 ml. This medicine may make you feel dizzy, so drive or operate machinery only if you are alert. Avoid consuming alcohol during the course, as it could lead to increased dizziness. Grandem 1 mg Injection 3 ml is not recommended in children below two years of age.
Drug-Drug Interaction: Grandem 1 mg Injection 3 ml may interact with antidepressants (fluoxetine, duloxetine), heart-related drugs (amiodarone, sotalol), antipsychotic drugs (pimozide), antibiotics (erythromycin), and St. John's wort, a plant-based medicine used for depression and mood disorders.
Drug-Food Interaction: Alcohol may increase dizziness when taken with Grandem 1 mg Injection 3 ml.
Drug-Disease Interaction: Before using Grandem 1 mg Injection 3 ml, let your doctor know if you have any stomach/intestinal problems like stomach ache, wind, feeling or being sick, difficulty passing stools, electrolyte imbalance (potassium, sodium or calcium), heart problems, liver or kidney diseases.
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Grandem 1 mg Injection 3 ml is used to treat Nausea and vomiting.
Grandem 1 mg Injection 3 ml contains Granisetron, an anti-emetic drug. It is a serotonin blocker that blocks the activity of serotonin, a chemical messenger that induces nausea and vomiting after treatments like chemotherapy and radiation therapy. Thus, Grandem 1 mg Injection 3 ml relieves post-operative nausea and vomiting symptoms.
Grandem 1 mg Injection 3 ml may cause constipation as one of its side effects. You can avoid it by including high-fibre food in your diet that improves your digestion. Limit the intake of alcohol to manage your constipation.
Grandem 1 mg Injection 3 ml should be used with caution if you have recent stomach/intestinal problems like stomach ache, wind, feeling or being sick, difficulty passing stools, heart rhythm disorder, a recent stomach or intestinal surgery, electrolyte imbalance (potassium, sodium or calcium), and liver or kidney diseases.
You are advised to complete the course prescribed by your doctor. Please do not stop taking this medicine unless advised by your doctor since it may lead to recurrent episodes of nausea and vomiting.
Common side effects of Grandem 1 mg Injection 3 ml include diarrhoea, constipation, stomach pain, weakness, headache, fever, drowsiness, trouble sleeping, pain, redness, and swelling at the injection site. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.
It is not known if Grandem 1 mg Injection 3 ml affects pregnancy. Please inform your doctor if you are pregnant or planning pregnancy before receiving Grandem 1 mg Injection 3 ml. The doctor will prescribe Grandem 1 mg Injection 3 ml only if clearly needed.
Few studies suggest that Grandem 1 mg Injection 3 ml is more effective than ondansetron. However, the doctor will decide which medicine is suitable and better for you based on your condition.
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