Granirex Syrup 10 ml
MRP ₹49
(Inclusive of all Taxes)
₹7.3 Cashback (15%)
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About Granirex Syrup
Granirex Syrup belongs to the class of ‘anti-emetic’ drugs, primarily used to treat nausea and vomiting caused by medical treatments, such as chemotherapy or radiation treatment for cancer. Nausea is defined as stomach discomfort and the sensation of an urge to vomit. Vomiting is the forcible, voluntary, or involuntary emptying of the contents of the stomach through the mouth.
Granirex Syrup contains an anti-emetic (eases vomiting symptoms) medicine, 'Granisetron', that belongs to the serotonin receptor antagonists or serotonin blockers class. It works by blocking the activity of serotonin (chemical messenger) in the brain that triggers nausea and vomiting during cancer treatment (chemotherapy or radiation therapy) or after surgery.
Your doctor will decide the dose and duration based on the severity of your medical condition. Common side effects of Granirex Syrup include diarrhoea, constipation, stomach pain, weakness, headache, fever, dizziness, drowsiness, trouble sleeping, and anxiety. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.
If you use other prescription or non-prescription medicines, inform your doctor before using Granirex Syrup. Let your doctor know if you have any liver, kidney, or heart diseases, stomach/intestinal problems, allergic reactions, or low potassium and magnesium levels in the blood before starting Granirex Syrup. Granirex Syrup may make you dizzy or drowsy, hence avoid driving if you are not mentally alert. Consult your doctor before taking Granirex Syrup if you are pregnant, planning for pregnancy, or breastfeeding. Avoid consuming alcohol along with Granirex Syrup as it could lead to increased drowsiness.
Uses of Granirex Syrup
Granirex Syrup is an antiemetic medication used primarily to prevent and treat nausea and vomiting, especially those caused by chemotherapy, radiation therapy, or surgery. The detailed uses of Granirex Syrup are as follows:
- Chemotherapy-Induced Nausea and Vomiting (CINV): Given before and sometimes after chemotherapy to prevent severe nausea and vomiting. Often used in combination with other antiemetics for a more effective result.
- Radiation-Induced Nausea and Vomiting (RINV): Prevents nausea associated with radiation therapy, especially to the abdomen or whole body.
- Postoperative Nausea and Vomiting (PONV): Used to prevent or treat nausea and vomiting after surgery under general anaesthesia.
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Directions for Use
- Granirex Syrup can be taken with or without food, or as your doctor advises.
- Follow your doctor's instructions on the dosage and timing of this medication.
- Swallow Granirex Syrup as a whole with a glass of water.
- Do not crush, break, or chew it.
Key Benefits
Granirex Syrup contains an anti-emetic drug, 'Granisetron', that treats nausea and vomiting caused by cancer treatment (chemotherapy or radiation therapy) or after surgery, etc. Granisetron belongs to the class of 5-HT3 receptor antagonists (also called serotonin receptor antagonists or serotonin blockers). When the cells lining the gastrointestinal tract are damaged by chemotherapy or radiation therapy, they release a natural substance called serotonin (5HT3, 5-hydroxytryptamine). This serotonin binds to serotonin receptors on nerves that induce nausea and vomiting. Granirex Syrup works by blocking the brain's serotonin activity and preventing post-operative nausea and vomiting.
How Granirex Syrup Works
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What if I have taken an overdose of Granirex Syrup
Drug Warnings
Granirex Syrup may cause serotonin syndrome/toxicity when used with other drugs like ecstasy (MDMA) and antidepressants. Hence it is suggested to seek medical advice if you are using any prescription or non-prescription medicines. Inform your doctor if you have a history of stomach/intestinal problems like stomach ache, wind, feeling or being sick, and difficulty passing stools, heart problems, electrolyte imbalance (potassium, sodium or calcium), and liver or kidney diseases before starting Granirex Syrup. Please consult your doctor if you are pregnant or breastfeeding if the doctor has advised you Granirex Syrup. Granirex Syrup may make you feel dizzy, so drive only if you are alert. Avoid consuming alcohol as it could lead to increased dizziness. Granirex Syrup is not recommended in children below two years of age.
Drug-Drug Interactions
Drug-Drug Interactions
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Taking Granirex Syrup 10 ml with Dronedarone can increase the risk of irregular heart rhythm.
How to manage the interaction:
Taking Granirex Syrup 10 ml with Dronedarone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
When Granirex Syrup 10 ml is taken with Saquinavir, can increase the risk of an irregular heart rhythm.
How to manage the interaction:
Taking Granirex Syrup 10 ml with Saquinavir is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Taking Granirex Syrup 10 ml with Cisapride can increase the risk of an irregular heart rhythm.
How to manage the interaction:
Taking Granirex Syrup 10 ml with Cisapride is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Taking Granirex Syrup 10 ml with mesoridazine can increase the risk of an irregular heart rhythm. I
How to manage the interaction:
Taking Mesoridazine with Granirex Syrup 10 ml is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Taking Granirex Syrup 10 ml with Thioridazine can increase the risk of an irregular heart rhythm.
How to manage the interaction:
Taking Granirex Syrup 10 ml with Thioridazine is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Taking Granirex Syrup 10 ml with Ziprasidone can increase the risk of abnormal heart rhythm.
How to manage the interaction:
Taking Granirex Syrup 10 ml with Ziprasidone is not recommended, as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
Taking Granirex Syrup 10 ml with Sparfloxacin can increase the chance of a serious abnormal heart rhythm.
How to manage the interaction:
Taking Granirex Syrup 10 ml with Sparfloxacin is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
Taking Granirex Syrup 10 ml with Pimozide can increase the risk of an irregular heart rhythm.
How to manage the interaction:
Taking Granirex Syrup 10 ml with Pimozide is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not stop using any medications without talking to a doctor.
Taking Granirex Syrup 10 ml with Procarbazine can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in body).
How to manage the interaction:
Co-administration of Granirex Syrup 10 ml with Procarbazine can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, blurred vision, muscle spasm, stomach cramp, nausea, vomiting, diarrhea, dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Using Granirex Syrup 10 ml together with Alfentanil can increase the risk of a serious condition called serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is a mood stabilizer).
How to manage the interaction:
Co-administration of Alfentanil with Granirex Syrup 10 ml can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, seek immediate medical attention. Do not discontinue any medications without consulting a doctor.
Drug-Food Interactions
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Diet & Lifestyle Advise
- Avoid chocolates, junk food, cheese, processed food, alcohol and smoking.
- You can try increasing your mindfulness by doing yoga, meditation, mindfulness-based cognitive therapy and stress reduction techniques.
- Drink enough water to stay hydrated and limit or avoid alcohol and caffeine.
- Include a diet rich in whole grains, vegetables and fruits. This is a healthier option than eating a lot of simple carbohydrates found in processed foods.
- You can include antioxidants in your daily diet like ashwagandha, omega-3 fatty acids, green tea and lemon balm.
- Try to spend time with your friends and family. Having a strong social network may help you lower your risk of anxiety.
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Alcohol
Safe if prescribed
You are recommended to limit or avoid alcohol consumption while taking Granirex Syrup. Alcohol intake, along with Granirex Syrup, may cause increased dizziness.
Pregnancy
Consult your doctor
It is not known if Granirex Syrup affects pregnancy. Please consult your doctor if you are pregnant or planning to conceive before using Granirex Syrup.
Breast Feeding
Consult your doctor
It is not known if this medicine passes into breast milk. Please consult your doctor before taking Granirex Syrup if you are a nursing mother.
Driving
Safe if prescribed
Granirex Syrup may make you feel dizzy that affects your mental ability. Do not drive or operate machinery if you experience dizziness.
Liver
Consult your doctor
Granirex Syrup should be cautiously used by patients with liver diseases. Please consult your doctor if you have a history of liver impairment before starting Granirex Syrup.
Kidney
Consult your doctor
Granirex Syrup should be cautiously used by patients with kidney problems. Please consult your doctor if you have a history of kidney impairment/kidney disease.
Children
Safe if prescribed
Safety and efficacy of Granirex Syrup are not established in children below 2 years of age.
Heart
Granirex Syrup should be taken with caution in patients with heart problems. Please inform your doctor about any existing heart problems before using Granirex Syrup.
Geriatrics
Consult your doctor
Granirex Syrup is safe for use in elderly patients if prescribed by the physician.
FAQs
Granirex Syrup is used to treat nausea and vomiting caused by medical treatments.
Granirex Syrup contains Granisetron, an anti-emetic drug. It is a serotonin blocker that blocks the activity of serotonin, a chemical messenger that induces nausea and vomiting after treatments like chemotherapy and radiation therapy. Thus, Granirex Syrup relieves from post-operative nausea and vomiting symptoms.
Granirex Syrup may cause constipation as one of its side effects. You can avoid it by including high fibre food in your diet that improves your digestion. Limit the intake of alcohol to manage your constipation.
Granirex Syrup should be used with caution if you have recent stomach/intestinal problems like stomach ache, wind, feeling or being sick or difficulty passing stools, heart problems, electrolyte imbalance (potassium, sodium or calcium), and liver or kidney diseases.
You are advised to complete the course prescribed by your doctor. Please do not stop taking this medicine unless advised by your doctor since it may lead to recurrent episodes of nausea and vomiting.
Take Granirex Syrup as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose.
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