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compositionComposition:HEPARIN-5000IU
prescription
Prescription Medicine
info
Hepaglan-5 Injection 5000Iu/5Ml

Hepaglan-5 Injection 5000Iu/5Ml is used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks. It contains Heparin, which works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation. Some people may experience haemorrhage (bleeding), thrombocytopenia (low platelets), hypersensitivity reactions, and elevations of liver enzyme (aminotransferase) levels. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

HEPARIN-5000IU

Manufacturer/Marketer :

Gland Pharma Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Hepaglan-5 Injection 5000Iu/5Ml

Hepaglan-5 Injection 5000Iu/5Ml is an injection used to prevent and treat blood clots in your veins, arteries, or lungs. It is medically prescribed to stop harmful clots from forming or growing larger, which helps protect you from serious heart or vascular conditions.

Because this medicine is given as an injection, you must use it consistently and exactly as scheduled to keep a steady amount in your blood. Your doctor will determine how often you need to inject it, and it can be given regardless of when you eat. Making healthy changes like staying active and drinking plenty of water can also support your treatment results.

While using Hepaglan-5 Injection 5000Iu/5Ml, you might notice mild bruising or soreness where you inject it. These are common, but you must contact your doctor immediately if you experience severe bleeding, unusual bruising, or dark, tarry stools.

Before starting this medicine, tell your doctor if you have high blood pressure, liver damage, or a history of bleeding disorders. Do not take this if you have active, uncontrolled bleeding or a severe drop in blood platelets from previous use of this type of medicine.

Certain medications like aspirin, as well as alcohol, can increase your risk of bleeding while using Hepaglan-5 Injection 5000Iu/5Ml. If you are pregnant, breastfeeding, or are an older adult, talk to your doctor to ensure this medicine is safe for your specific situation.

Uses of Hepaglan-5 Injection 5000Iu/5Ml

Hepaglan-5 Injection 5000Iu/5Ml is used to prevent and treat harmful blood clots in different medical situations. The detailed uses of Hepaglan-5 Injection 5000Iu/5Ml are as follows: 

  • Deep vein thrombosis (DVT) and pulmonary embolism (PE): Hepaglan-5 Injection 5000Iu/5Ml helps stop blood clots from forming in your legs or travelling to your lungs, which can be life-threatening.
  • Blood clots during medical procedures: It prevents blood from clotting during heart surgeries, blood transfusions, or kidney dialysis.
  • Arterial blood clots: It is used to treat or prevent clots in the arteries that could lead to heart attacks or other serious circulatory problems.
     

Key Benefits

Hepaglan-5 Injection 5000Iu/5Ml helps prevent the formation and growth of harmful blood clots, providing important protection in situations where the risk of clotting is increased. Its rapid onset of action makes it particularly valuable when immediate anticoagulation is needed.

  • Rapid Protection Against Blood Clots: Because it begins working soon after administration, Hepaglan-5 Injection 5000Iu/5Ml helps reduce the risk of dangerous clot formation during and after surgeries, hospital stays, or other high-risk medical situations.
  • Supports Healthy Blood Flow and Recovery: By preventing existing clots from getting larger and allowing the body's natural processes to break them down, Hepaglan-5 Injection 5000Iu/5Ml helps maintain blood circulation and may reduce symptoms such as swelling and discomfort associated with blood clots.

Directions for Use

This medicine is given as an injection, either under the skin (subcutaneously) or directly into a vein (intravenously). If you are injecting this medicine at home, follow these steps:

  • Wash your hands thoroughly with soap and water before handling the medicine.
  • Clean the injection site on your skin with an alcohol wipe and let it dry.
  • Gently pinch a fold of skin and insert the needle fully at the angle recommended by your doctor.
  • Inject the medicine slowly, then remove the needle and press gently with a clean cotton ball. Do not rub the site.
  • Dispose of the used needle immediately in a safe sharps container.

Always rotate your injection sites to prevent skin irritation. Be sure to follow your doctor's exact instructions on how and when to inject this medicine.

How Hepaglan-5 Injection 5000Iu/5Ml Works

Hepaglan-5 Injection 5000Iu/5Ml contains heparin, which works as an anticoagulant, commonly known as a blood thinner. It does not actually thin your blood, but instead blocks certain natural proteins in your body that are responsible for forming clots. By keeping these proteins inactive, the medicine prevents new clots from starting and stops existing clots from getting any bigger, allowing your body to naturally break them down over time.
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Alcohol

Caution

You are recommended to avoid consumption of alcohol with Hepaglan-5 Injection 5000Iu/5Ml as it may cause severe bleeding in the stomach and harmful side effects to the liver.

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Pregnancy

Caution

Hepaglan-5 Injection 5000Iu/5Ml is a Category C pregnancy drug and should be given to pregnant women only if clearly needed and has more benefits than risks. Preservative-free forms are preferred in pregnant women as preservatives such as benzyl alcohol may cross the placenta.

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Breast Feeding

Caution

Hepaglan-5 Injection 5000Iu/5Ml should be given to breastfeeding mothers only if clearly needed and has more benefits than risks.

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Driving

Safe if prescribed

Hepaglan-5 Injection 5000Iu/5Ml usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Hepaglan-5 Injection 5000Iu/5Ml should be given with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Hepaglan-5 Injection 5000Iu/5Ml should be given with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Hepaglan-5 Injection 5000Iu/5Ml is not recommended for children below 2 months.

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Heart

Caution

Hepaglan-5 Injection 5000Iu/5Ml can be used in heart patients for the prevention of blood clots. However, caution should be exercised while receiving Hepaglan-5 Injection 5000Iu/5Ml.

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Geriatrics

Caution

Geriatric patients can receive Hepaglan-5 Injection 5000Iu/5Ml if prescribed by the physician. It's important to use it under close medical supervision with tailored dosing and regular monitoring.

What if I have taken an overdose of Hepaglan-5 Injection 5000Iu/5Ml

The overdose of Hepaglan-5 Injection 5000Iu/5Ml is unlikely as it is administered by a doctor. Too much heparin may cause bleeding. Therefore, if you suspect any adverse reactions or unusual symptoms or more severe bleeding while on treatment with Hepaglan-5 Injection 5000Iu/5Ml, please inform your doctor immediately.

Diet & Lifestyle Advise

  • Avoid injury risks: Use a soft-bristle toothbrush and an electric razor to lower your risk of bleeding from minor cuts.
  • Be cautious with activities: Skip high-impact or contact sports where you might bump your head or body, as this can cause internal bleeding.
  • Stay hydrated: Drink plenty of water unless your doctor tells you otherwise, as good hydration supports healthy circulation while you are receiving heparin treatment.
  • Keep a consistent diet: Avoid making sudden, drastic changes to your diet, especially regarding herbs and supplements, without talking to your doctor.
     

Have a query?

How Soon It Starts Working

The time required for Hepaglan-5 Injection 5000Iu/5Ml to start to work: The time required for Hepaglan-5 Injection 5000Iu/5Ml to start to work is immediately after IV and 20 to 60 minutes after subcutaneous administration. The time for which the effects of Hepaglan-5 Injection 5000Iu/5Ml last: The duration of action for Hepaglan-5 Injection 5000Iu/5Ml is unknown.

What if you forget to take Hepaglan-5 Injection 5000Iu/5Ml

As Hepaglan-5 Injection 5000Iu/5Ml is administered under medical supervision, the chances of missing a dose are less. However, if you have any concerns, contact your doctor.

Storage

Store Hepaglan-5 Injection 5000Iu/5Ml at room temperature, between 20°C and 25°C (68°F to 77°F). Do not freeze this medicine, and keep it away from direct heat and light.

Drug Warnings

  • Inspect the Solution Before Injection: Always inspect the liquid vial before use. Do not inject the medicine if you notice particles or if the solution appears discoloured.
  • Never Reuse Needles or Syringes: Always use a new needle and syringe for each injection, as reusing them may increase the risk of serious infections.
  • Avoid Rubbing the Injection Site: Do not rub the skin after injecting Hepaglan-5 Injection 5000Iu/5Ml, as this may increase the risk of bruising, irritation, or pain at the injection site.
  • Carry Medical Identification: Wear a medical alert bracelet or carry a card stating that you are using an injectable blood thinner so healthcare professionals can provide appropriate care in an emergency.
  • Inform Healthcare Providers Before Procedures: Inform all healthcare providers, including your dentist, that you are using Hepaglan-5 Injection 5000Iu/5Ml before any medical procedure or surgery is scheduled.

Drug-Drug Interactions

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Drug-Drug Interactions


Inform your doctor if you are taking any of the following medicines, as they may interact with Hepaglan-5 Injection 5000Iu/5Ml: 

  • Aspirin and NSAIDs (like ibuprofen): These can greatly increase your risk of stomach bleeding and other bleeding complications when used with Hepaglan-5 Injection 5000Iu/5Ml.
  • Other blood thinners: Combining this medicine with oral anticoagulants can significantly raise your risk of bleeding.


Drug-Food Interactions


Certain foods, beverages, herbs, and dietary supplements may affect how Hepaglan-5 Injection 5000Iu/5Ml works or increase the risk of side effects. Examples include: 

  • Herbal supplements: Supplements like ginkgo biloba, garlic, ginger, and high doses of vitamin E can increase your risk of bleeding when taken with Hepaglan-5 Injection 5000Iu/5Ml.


Drug-Disease Interactions


Inform your doctor if you have any of the following medical conditions before using Hepaglan-5 Injection 5000Iu/5Ml, as additional monitoring or treatment adjustments may be required: 

  • Active bleeding: Do not use this medicine if you currently have a major bleeding medical issue, such as a bleeding ulcer.
  • Severe liver damage or kidney disease: These conditions can affect how your body processes the medicine, raising the risk of side effects.
  • Uncontrolled high blood pressure: High blood pressure can increase the risk of bleeding in the brain while using this medicine.
HeparinTiclopidine
Critical
HeparinOritavancin
Critical

Drug-Drug Interactions

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HeparinTiclopidine
Critical
How does the drug interact with Hepaglan-5 Injection 5000Iu/5Ml:
Taking Ticlopidine with Hepaglan-5 Injection 5000Iu/5Ml can increase the risk of bleeding.

How to manage the interaction:
Taking Ticlopidine with Hepaglan-5 Injection 5000Iu/5Ml is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
HeparinOritavancin
Critical
How does the drug interact with Hepaglan-5 Injection 5000Iu/5Ml:
Using Hepaglan-5 Injection 5000Iu/5Ml with Oritavancin can make Hepaglan-5 Injection 5000Iu/5Ml less effective as a therapy.

How to manage the interaction:
Hepaglan-5 Injection 5000Iu/5Ml is not recommended within 120 hours (5 days) of taking oritavancin. Oritavancin can interfere with certain of the major coagulation tests used to assess Hepaglan-5 Injection 5000Iu/5Ml's effectiveness and safety, it can be taken only if prescribed by a doctor. Do not discontinue any medications without a doctor's advice.
HeparinBazedoxifene
Critical
How does the drug interact with Hepaglan-5 Injection 5000Iu/5Ml:
When Hepaglan-5 Injection 5000Iu/5Ml is taken with bazedoxifene the effects of Hepaglan-5 Injection 5000Iu/5Ml are reduced by bazedoxifene.

How to manage the interaction:
Taking Bazedoxifene with Hepaglan-5 Injection 5000Iu/5Ml is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
HeparinAlteplase
Critical
How does the drug interact with Hepaglan-5 Injection 5000Iu/5Ml:
Taking Alteplase with Hepaglan-5 Injection 5000Iu/5Ml can increase the risk of bleeding.

How to manage the interaction:
Taking Hepaglan-5 Injection 5000Iu/5Ml with Alteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
HeparinTenecteplase
Critical
How does the drug interact with Hepaglan-5 Injection 5000Iu/5Ml:
Taking Tenecteplase with Hepaglan-5 Injection 5000Iu/5Ml can increase the risk of bleeding.

How to manage the interaction:
Taking Hepaglan-5 Injection 5000Iu/5Ml with Tenecteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
HeparinMifepristone
Critical
How does the drug interact with Hepaglan-5 Injection 5000Iu/5Ml:
Taking Mifepristone with Hepaglan-5 Injection 5000Iu/5Ml can increase the risk of negative side effects.

How to manage the interaction:
Taking Hepaglan-5 Injection 5000Iu/5Ml with Mifepristone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
HeparinDasatinib
Severe
How does the drug interact with Hepaglan-5 Injection 5000Iu/5Ml:
Taking Dasatinib with Hepaglan-5 Injection 5000Iu/5Ml can increase the risk and severity of bleeding.

How to manage the interaction:
Although there is a possible interaction between Hepaglan-5 Injection 5000Iu/5Ml and Dasatinib, you can take these medicines together if prescribed by a doctor. However, consult a doctor, if you experience bruising, dizziness, red or black, tarry stools, severe headache, and weakness. Do not stop using any medications without a doctor's advice.
HeparinProtamine
Severe
How does the drug interact with Hepaglan-5 Injection 5000Iu/5Ml:
When Protamine and Hepaglan-5 Injection 5000Iu/5Ml are used together, can increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Protamine and Hepaglan-5 Injection 5000Iu/5Ml, but it can be taken if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
HeparinSulfadiazine
Severe
How does the drug interact with Hepaglan-5 Injection 5000Iu/5Ml:
Sulfadiazine enhances the effects of Hepaglan-5 Injection 5000Iu/5Ml by slowing its breakdown.

How to manage the interaction:
Co-administration of Sulfadiazine with Hepaglan-5 Injection 5000Iu/5Ml can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
HeparinTirofiban
Severe
How does the drug interact with Hepaglan-5 Injection 5000Iu/5Ml:
Taking Tirofiban with Hepaglan-5 Injection 5000Iu/5Ml can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Hepaglan-5 Injection 5000Iu/5Ml and Tirofiban, you can take these medicines together if prescribed by a doctor. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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HEPARIN-5000IUHerbal products/medicines
Moderate

Drug-Food Interactions

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HEPARIN-5000IUHerbal products/medicines
Moderate
Common Foods to Avoid:
Garlic Pill

How to manage the interaction:
Taking Hepaglan-5 Injection 5000Iu/5Ml along with herbs and supplements such as garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba can lead to an increased risk of bleeding Avoid taking herbs and supplements such as garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba while taking Hepaglan-5 Injection 5000Iu/5Ml.

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTICOAGULANTS / ANTITHROMBOTICS. ANTICONVULSANTS]

FAQs

Hepaglan-5 Injection 5000Iu/5Ml is used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks.
Hepaglan-5 Injection 5000Iu/5Ml works by reducing the blood's ability to form harmful clots. It helps prevent existing clots from getting larger and reduces the risk of new clots forming, thereby helping to prevent complications such as deep vein thrombosis, pulmonary embolism, stroke, and heart attack.
Yes, Hepaglan-5 Injection 5000Iu/5Ml may increase potassium levels in the blood (hyperkalaemia), especially when given for a long period. Therefore, it is advised to inform your doctor if you are taking any medicines that increase potassium levels in the blood.
Yes, Hepaglan-5 Injection 5000Iu/5Ml may cause bleeding. If you notice purple spots on the skin or unusual bruising, blood in urine, black tarry stools, unusual bleeding from gums or nose, please inform your doctor immediately as these are signs of bleeding more easily.
Yes, Hepaglan-5 Injection 5000Iu/5Ml may cause allergic reactions such as fever, chills, difficulty in breathing, wheezing, blue shade to the lips, swelling of lips, and eyes. It is not necessary for everyone taking Hepaglan-5 Injection 5000Iu/5Ml to experience an allergic reaction. However, if you notice any of these signs, please inform your doctor immediately.
Yes, many patients are taught how to inject Hepaglan-5 Injection 5000Iu/5Ml under the skin at home. Your healthcare provider will show you exactly how to prepare and inject the medicine safely. Talk to your doctor if you have any questions about the injection process.
Mild bleeding can sometimes happen, but frequent nosebleeds or bleeding gums can be a sign that your dose needs adjustment. You should contact your healthcare provider right away to have your symptoms evaluated. Talk to your doctor.
It is best to avoid or strictly limit alcohol while using Hepaglan-5 Injection 5000Iu/5Ml, as alcohol can increase your risk of stomach bleeding and affect how your blood clots. Talk to your doctor or pharmacist about safe alcohol limits.
This medicine is often preferred over other blood thinners during pregnancy because it does not cross the placenta to reach the baby. However, it must still be used under close medical supervision. Talk to your doctor to see if this is right for you.
Your doctor needs to check how quickly your blood clots to ensure you are getting the correct dose. These tests help prevent complications like bleeding or further clotting. Talk to your doctor.
No, you should avoid taking ibuprofen, aspirin, naproxen, or other NSAID pain relievers unless specifically directed by your doctor, as they can significantly increase the risk of bleeding while using Hepaglan-5 Injection 5000Iu/5Ml. Acetaminophen (paracetamol) may be a safer alternative, but always consult your doctor or pharmacist before taking any additional medicines.
For minor cuts, apply firm, direct pressure with a clean cloth for at least 5 to 10 minutes. If the bleeding does not stop, or if you experience a hard blow to the head or body, seek medical help immediately. Talk to your doctor.
Long-term use of Hepaglan-5 Injection 5000Iu/5Ml can sometimes cause temporary hair thinning or loss. This side effect usually stops once you finish the treatment. Talk to your doctor if this concerns you.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

INDIA

Manufacturer/Marketer address

Gland Pharma Limited, 6-3-865/1/2, Greenland Apartments, Ameerpet, Hyderabad - 500016, India
Other Info - HEP0257

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