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compositionComposition:RIVASTIGMINE-18MG
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Prescription Medicine
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Hetriva 18 Transdermal Patch used to treat dementia (memory loss) associated with Alzheimer's and Parkinson's disease. It increases the levels of a brain chemical called acetylcholine, which helps nerve cells to communicate more easily. It slows cognitive decline and improves cognitive functions, including memory, cognition, and awareness. It also helps patients to perform daily activities more easily and improve their overall quality of life.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

RIVASTIGMINE-18MG

Manufacturer/Marketer :

Hetero Healthcare Pvt Ltd

Consume Type :

Topical

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Hetriva 18 Transdermal Patch

Hetriva 18 Transdermal Patch is a prescription topical treatment used to manage memory and thinking problems in people with mild to moderate Alzheimer's disease. It is also used to treat dementia associated with Parkinson's disease. This medication helps by supporting communication between nerve cells in the brain.

For this medicine to work effectively, you must apply a new patch every single day at the same time. Consistent daily use ensures a steady flow of the medication through your skin into your bloodstream. Staying physically active, keeping a regular sleep schedule, and eating nutritious meals can also help support your overall brain health while using this treatment.

While using Hetriva 18 Transdermal Patch, you may experience mild side effects such as skin redness where the patch was applied, mild nausea, or temporary loss of appetite. However, if you develop severe vomiting, persistent diarrhoea, fainting, or an unusually slow heartbeat, you must contact your doctor immediately.

Before starting this medicine, tell your doctor if you have a history of heart rhythm problems, stomach ulcers, asthma, or difficulty urinating. Do not take this if you have previously had a severe skin reaction, like blistering or intense swelling, from using this specific patch.

This medication can interact with other treatments, such as certain heart medicines or drugs used during surgery, and drinking alcohol while using it can increase dizziness. If you are pregnant, planning to become pregnant, breastfeeding, or are an older adult, talk to your doctor or pharmacist to make sure this is safe for your specific situation.

Uses of Hetriva 18 Transdermal Patch

Hetriva 18 Transdermal Patch helps manage the symptoms of dementia by improving memory, thinking, and daily functioning. Your doctor may recommend it for the following conditions:

  • Alzheimer's disease dementia: Helps manage mild-to-moderate confusion, memory loss, and thinking problems.
  • Parkinson's disease dementia: Improves cognitive function and daily functioning in people experiencing dementia related to Parkinson's disease.

Key Benefits

Hetriva 18 Transdermal Patch helps manage the symptoms of dementia by supporting memory, thinking, and daily functioning. Key benefits include:

  • Supports memory and daily activities: Helps improve memory, awareness, and the ability to carry out everyday tasks, allowing many people to remain more independent for longer.
  • Provides continuous medicine delivery: The patch releases the medicine steadily over 24 hours, helping maintain consistent levels of the medicine in the body throughout the day.
  • May reduce stomach-related side effects: Because the medicine is absorbed through the skin rather than taken by mouth, it may cause fewer stomach problems, such as nausea and vomiting.
  • Convenient once-daily application: A single patch provides all-day treatment, making it easier to follow the prescribed treatment plan.
Side effects of Hetriva 18 Transdermal Patch
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

Directions for Use

  • Apply the patch as prescribed by your doctor, typically once a day, to clean, dry, and hairless skin on the upper or lower back, upper arm, or chest.
  • Press the patch firmly onto the skin for at least 30 seconds to ensure it sticks.
  • Do not apply the patch to broken, irritated, or wounded skin, and avoid contact with your eyes, mouth, or mucous membranes.
  • Replace the patch with a new one as directed by your doctor and apply it to a different area of skin to avoid irritation.

How Hetriva 18 Transdermal Patch Works

Hetriva 18 Transdermal Patch contains rivastigmine, a cholinesterase inhibitor that helps increase the levels of acetylcholine, a natural chemical messenger in the brain that is important for memory, learning, thinking, and daily functioning. People with dementia often have reduced levels of acetylcholine, which contributes to problems with memory and cognition. By blocking the enzyme that breaks down acetylcholine, the medicine increases the amount of this chemical available in the brain. This improves communication between nerve cells, helping to reduce the symptoms of dementia and support memory, thinking, and everyday activities.
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Alcohol

Unsafe

It is advised to avoid alcohol consumption while using Hetriva 18 Transdermal Patch. Alcohol intake, along with Hetriva 18 Transdermal Patch, may cause increased dizziness and drowsiness. Please consult your doctor for more information.

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Pregnancy

Caution

Hetriva 18 Transdermal Patch should be used during pregnancy only if the benefit outweighs the risk. Please consult your doctor before using Hetriva 18 Transdermal Patch if you are pregnant or planning to conceive.

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Breast Feeding

Caution

It is not known if Hetriva 18 Transdermal Patch is excreted into breast milk. Please consult your doctor before using Hetriva 18 Transdermal Patch if you are breastfeeding.

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Driving

Caution

Hetriva 18 Transdermal Patch may cause dizziness or drowsiness. Do not drive if you experience any symptoms that affect your ability to drive or operate machinery.

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Liver

Caution

Please consult your doctor before using Hetriva 18 Transdermal Patch if you have liver problems.

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Kidney

Caution

Please consult your doctor before using Hetriva 18 Transdermal Patch if you have kidney impairment.

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Children

Caution

It is unknown whether Hetriva 18 Transdermal Patch is safe for use in patients under 18 years of age. Please consult a physician for further information.

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Heart

Caution

Hetriva 18 Transdermal Patch should be used with caution in patients with cardiovascular disease. Please inform your doctor about any existing heart problems before using Hetriva 18 Transdermal Patch.

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Geriatrics

Caution

Hetriva 18 Transdermal Patch should be used with caution in elderly patients. Please consult your doctor before use.

What if I have taken an overdose of Hetriva 18 Transdermal Patch

If you accidentally apply more than one patch at a time, or if a patch is swallowed, remove all patches immediately and seek emergency medical attention.

Diet & Lifestyle Advise

  • Stay well-hydrated: Drink plenty of water throughout the day. This is especially important to prevent dehydration if you experience mild stomach upset or diarrhoea.
  • Eat small, frequent meals: If you experience a loss of appetite, eating smaller, nutrient-rich meals throughout the day can help you maintain your weight and energy levels.
  • Create a consistent routine: Keep daily activities, meal times, and sleeping schedules as consistent as possible, as structured routines can greatly support cognitive function.
  • Engage in brain-stimulating activities: Pair your treatment with gentle mental exercises like puzzles, reading, or social conversations to help maintain cognitive engagement.
health query

Have a query?

How Soon It Starts Working

  • The time required for Hetriva 18 Transdermal Patch to start to work: The time required for Hetriva 18 Transdermal Patch to show its action is unknown.
  • The time for which the effects of Hetriva 18 Transdermal Patch last: The duration of action for Hetriva 18 Transdermal Patch is unknown.

What if you forget to take Hetriva 18 Transdermal Patch

If you forget to change your patch at your usual time, apply a new patch as soon as you remember. Change it again at your regular time the next day. Do not apply two patches at the same time to make up for a missed one. If you have missed wearing your patch for more than three days, do not apply a new one until you have spoken to your doctor, as you may need to restart at a lower dose.

Storage

• Store Hetriva 18 Transdermal Patch at room temperature, ideally between 20°C and 25°C (68°F and 77°F).

Drug Warnings

  • Apply only one patch at a time: Always remove the old patch before applying a new one. Wearing more than one patch can lead to an overdose.
  • Do not damage the patch: Do not cut, tear, or damage the patch, as this may cause the medicine to be released too quickly.
  • Avoid heat exposure: Keep the patch away from external heat sources, such as heating pads, electric blankets, hot tubs, saunas, or prolonged direct sunlight, as heat can increase the amount of medicine absorbed.
  • Check the patch regularly: Ensure the patch remains firmly attached, especially after bathing, showering, or swimming. If it falls off, follow your doctor's or the product's instructions before applying a new one.
  • Keep track of patch changes: Record the date and time you apply each patch to help ensure it is replaced according to your prescribed schedule.

Drug-Drug Interactions

verifiedApollotooltip
  • Anticholinergic medications: May reduce the effectiveness of Hetriva 18 Transdermal Patch, and Hetriva 18 Transdermal Patch can lower the effectiveness of these medications.
  • Beta-blockers: Combining these heart medications with Hetriva 18 Transdermal Patch can cause an excessively slow heartbeat or fainting.
  • Cholinergic agonists: May increase the risk of severe side effects when used at the same time as this medicine.
RivastigmineMetrizamide
Severe
RivastigmineTramadol
Severe

Drug-Drug Interactions

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RivastigmineMetrizamide
Severe
How does the drug interact with Hetriva 18 Transdermal Patch:
Taking Hetriva 18 Transdermal Patch and Metrizamide together may increase the risk of developing seizures (fits).

How to manage the interaction:
Although taking Hetriva 18 Transdermal Patch and Metrizamide together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms like muscle spasms, lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, shaking of hands and legs, jitteriness, restlessness, pacing, and foot tapping, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
RivastigmineTramadol
Severe
How does the drug interact with Hetriva 18 Transdermal Patch:
Taking Tramadol with Hetriva 18 Transdermal Patch can significantly increase the risk of seizures (fits).

How to manage the interaction:
Taking Hetriva 18 Transdermal Patch with tramadol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, shaking of hands and legs, jitteriness, restlessness, pacing, and foot tapping, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RivastigminePropranolol
Severe
How does the drug interact with Hetriva 18 Transdermal Patch:
Coadministration of Hetriva 18 Transdermal Patch with propranolol can cause an abnormally slow heart rate and low blood pressure.

How to manage the interaction:
Although taking Propranolol together with Hetriva 18 Transdermal Patch can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor if you experience lightheadedness, dizziness, fainting, or irregular heartbeat. Do not discontinue any medicine without consulting a doctor.
RivastigmineBupropion
Severe
How does the drug interact with Hetriva 18 Transdermal Patch:
Talking bupropion and Hetriva 18 Transdermal Patch together can increase risk of having seizures (fits).

How to manage the interaction:
Co-administration of bupropion along with Hetriva 18 Transdermal Patch can lead to an interaction, it can be taken if recommended by a doctor. In case you experience any symptoms like muscle spasms or movements, lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, shaking of hands and legs, jitteriness, restlessness, pacing, and foot tapping, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Avoid or limit alcohol while using this medicine, as it can increase the risk of dizziness, confusion, and drowsiness.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- ALZHEIMER'S AGENTS]

FAQs

Apply Hetriva 18 Transdermal Patch to clean, dry, healthy, hairless skin on the upper back, lower back, upper arm, or chest. Do not apply it to broken, irritated, or damaged skin, and avoid areas where tight clothing may rub the patch. Do not apply creams, lotions, oils, or powders to the application site, as they may affect adhesion. Rotate application sites and avoid using the same area again for at least 14 days to help prevent skin irritation.
Always remove your old patch before applying a new one. Wearing more than one patch at the same time can lead to an overdose. If you accidentally apply a new patch without removing the old one, remove the extra patch immediately and contact your doctor or seek emergency medical attention if you develop symptoms such as severe nausea, vomiting, dizziness, or fainting.
Yes, you can bathe, shower, or swim while wearing the patch. However, avoid rubbing the patch area excessively and do not expose it to hot water or direct heat sources like saunas, as heat can affect how the medicine is absorbed. Talk to your doctor if you have concerns.
If the patch falls off, apply a new patch to a different skin site for the rest of the day. Replace it at your usual scheduled time the next day. Talk to your doctor or pharmacist if this happens frequently.
No, you must never cut or damage the patch. Cutting it ruins the structure of the patch and can cause all of the medicine to be released into your body at once, which is dangerous. Talk to your doctor if you feel your dose needs adjusting.
You should replace the patch once every 24 hours. Try to change it at the same time every day to maintain a steady level of medicine in your body. Talk to your doctor if you struggle to keep a regular schedule.
Rotating the site daily prevents skin irritation and allows the skin to recover. Do not apply a new patch to the exact same spot for at least 14 days. Talk to your doctor if you experience persistent skin redness or itching.
It is best to limit or avoid alcohol while using this medicine. Alcohol can increase side effects like dizziness, confusion, and drowsiness. Talk to your doctor or pharmacist about safe alcohol limits for you.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

2Nd Floor, 8-3-166/7/1 Erragadda, Hyderabad-500018
Other Info - HET0072

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