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compositionComposition:ITRACONAZOLE-100MG
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Prescription Medicine
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I-Tyza Sb 100 Cap is an antifungal medicine used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. It contains Itraconazole, which works by killing fungi. Some people may experience side effects such as nausea, headache, diarrhoea, tiredness, cough, cold, throat pain, back pain and stomach pain. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ITRACONAZOLE-100MG

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About I-Tyza Sb 100 Cap

I-Tyza Sb 100 Cap is an antifungal medicine used to treat a wide variety of fungal infections. It is commonly prescribed for infections affecting the nails, skin, mouth, throat, or lungs. By stopping the growth of fungi, this medicine helps clear the infection and prevents it from spreading.

To get the best results, you must take I-Tyza Sb 100 Cap consistently at the same times every day as directed by your healthcare provider. If you are taking the capsule form, it is highly recommended to take it with a full meal to ensure your body absorbs the medication properly. Keeping your skin clean and dry and wearing breathable cotton clothing can also support your recovery.

While taking I-Tyza Sb 100 Cap , some people may experience mild side effects like an upset stomach, nausea, or headaches. However, you must contact your doctor immediately if you experience signs of liver damage, such as yellowing of the skin or eyes, dark urine, or severe fatigue.

Talk to your doctor before starting this medicine if you have a history of heart problems, liver disease, or kidney issues. Do not take this if you have heart failure or a history of congestive heart failure, as this medication can make these conditions worse.

I-Tyza Sb 100 Cap can interact with several other medications, including certain blood thinners, cholesterol-lowering drugs, and acid reducers, which can lower its effectiveness. Avoid drinking alcohol while taking this medicine, as it can increase the risk of liver damage. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, consult your doctor before using this medicine.

Uses of I-Tyza Sb 100 Cap

Your doctor may prescribe I-Tyza Sb 100 Cap to treat several conditions, including:

  • Fungal nail infections (onychomycosis): I-Tyza Sb 100 Cap helps clear fungal infections in both toenails and fingernails, allowing healthy, normal nails to grow back over time.
  • Ringworm and athlete's foot (tinea infections): It treats stubborn skin infections by stopping the spread of the fungus on the surface of the skin, relieving itching and scaling.
  • Thrush (oral candidiasis): It clears yeast infections in the mouth and throat, reducing pain and making swallowing comfortable again.
  • Systemic fungal infections: It treats deeper, more serious fungal infections that can affect internal organs like the lungs, helping your body fight off the infection.

Key Benefits

I-Tyza Sb 100 Cap offers reliable relief from the uncomfortable symptoms of fungal infections, helping you return to your normal daily routine.

  • Targeted clearance: It works directly at the site of the infection, whether deep in the nail bed or on the skin surface.
  • Convenient oral routine: Being an oral medication, it treats widespread or deep-seated infections that topical creams cannot reach.
  • Long-lasting protection: The medicine remains in your skin and nail tissues for some time even after you finish the course, helping prevent the infection from returning.
Side effects of I-Tyza SB 100 Capsule
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Eat potassium-rich foods like avocados, bananas, spinach, and potatoes.
  • Stay hydrated by drinking plenty of water.
  • Exercise regularly and maintain healthy weight.
  • Manage stress.
  • Prioritize 7-9 hours of sleep each night to help your body and mind recharge.
  • Avoid smoking and limit intake of caffeine.
  • Practice stress-reducing activities like meditation, yoga, or deep breathing to help calm your mind and body.
  • Avoid stimulants and illegal drugs.
  • Call your doctor if it worsens.

Directions for Use

I-Tyza Sb 100 Cap offers reliable relief from the uncomfortable symptoms of fungal infections, helping you return to your normal daily routine.

  • Targeted clearance: It works directly at the site of the infection, whether deep in the nail bed or on the skin surface.
  • Convenient oral routine: Being an oral medication, it treats widespread or deep-seated infections that topical creams cannot reach.
  • Long-lasting protection: The medicine remains in your skin and nail tissues for some time even after you finish the course, helping prevent the infection from returning.

How I-Tyza Sb 100 Cap Works

I-Tyza Sb 100 Cap contains Itraconazole, an antifungal that works by inhibiting the production of ergosterol (a main component of the cell membranes of fungi). This weakens and damages the fungal cell membranes that are essential for their survival, as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, it causes the main components of fungal cells to leak out, killing fungi and clearing the fungal infection.
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Alcohol

Unsafe

Avoid consumption of alcohol with I-Tyza Sb 100 Cap as it may increase the risk of liver problems and other adverse effects.

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Pregnancy

Unsafe

I-Tyza Sb 100 Cap is category C pregnancy drug and is unsafe for pregnant women as it may cause harm to the unborn baby. Therefore, inform your doctor if you are pregnant or planning for pregnancy before taking I-Tyza Sb 100 Cap .

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Breast Feeding

Consult your doctor

I-Tyza Sb 100 Cap is excreted in human milk and may harm the baby. Therefore, I-Tyza Sb 100 Cap is given to breastfeeding mothers only if doctor thinks benefits are greater than risks.

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Driving

Unsafe

I-Tyza Sb 100 Cap may cause dizziness, hearing loss, double or blurred vision in some people. Therefore, drive only if you alert after taking I-Tyza Sb 100 Cap .

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Liver

Caution

Take I-Tyza Sb 100 Cap with caution, especially if you have a history of liver disease. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take I-Tyza Sb 100 Cap with caution, especially if you have a history of kidney disease. The dose may be adjusted by your doctor as required.

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Children

Unsafe

I-Tyza Sb 100 Cap is not recommended for children below 12 years as the safety and effectiveness were not established.

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Heart

Unsafe

I-Tyza Sb 100 Cap is not recommended for use in heart patients as it can lead to cardiovascular effects.

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Geriatrics

Caution

Elderly patients taking I-Tyza Sb 100 Cap should maintain caution during the treatment, as it is known to cause side effects like hearing loss or age-related problems.

What if I have taken an overdose of I-Tyza Sb 100 Cap

If you take too much of this medication, seek immediate medical attention or call a poison control center right away.

Diet & Lifestyle Advise

  • Take with acidic drinks if needed: If you take stomach acid reducers, taking I-Tyza Sb 100 Cap capsules with an acidic drink like cola can help your body absorb the medicine better.
  • Keep infected areas dry: Fungi thrive in warm, moist environments. Dry your skin thoroughly after showering, especially between your toes and in skin folds.
  • Wear breathable clothing: Choose loose-fitting cotton clothing and breathable leather or canvas shoes to reduce moisture buildup.
  • Avoid sharing personal items: Do not share towels, nail clippers, socks, or footwear with others to prevent spreading or re-infecting yourself.
health query

Have a query?

How Soon It Starts Working

  • The time required for I-Tyza Sb 100 Cap to start to work: I-Tyza Sb 100 Cap ideally shows its action within 5 hours after administration.
  • The time for which the effects of I-Tyza Sb 100 Cap last: The effect of I-Tyza Sb 100 Cap lasts for 16 to 28 hours.

What if you forget to take I-Tyza Sb 100 Cap

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store I-Tyza Sb 100 Cap at room temperature, ideally between 15°C and 25°C (59°F to 77°F). • Keep the medication in its original container, tightly closed, to protect it from light and direct moisture.

Drug Warnings

  • Monitor your liver: Your doctor may require regular blood tests to check your liver function while you are taking this medicine.
  • Check the oral liquid: If you are using the liquid form, inspect the solution before use; it should be clear and free of particles.
  • Watch for heart failure signs: Stop taking the medication and seek emergency care if you develop unexpected shortness of breath or swelling in your ankles.
  • Limit acid reducers: Avoid taking antacids within 2 hours of taking I-Tyza Sb 100 Cap capsules, as they can prevent the medicine from being absorbed properly.

Drug-Drug Interactions

verifiedApollotooltip

Inform your doctor if you are taking any of the following medicines, as they may interact.

  • Acid reducers (antacids, PPIs): May lower the absorption of I-Tyza Sb 100 Cap , making it less effective.
  • Statins (cholesterol-lowering drugs): I-Tyza Sb 100 Cap can increase the levels of these drugs in your blood, increasing the risk of muscle damage.
  • Blood thinners: Taking I-Tyza Sb 100 Cap with certain blood thinners can increase the risk of bleeding.
  • Heart rhythm medications: Combining these can lead to serious, life-threatening heart rhythm issues.
ItraconazoleTicagrelor
Critical
ItraconazoleErgotamine
Critical

Drug-Drug Interactions

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ItraconazoleTicagrelor
Critical
How does the drug interact with I-Tyza SB 100 Capsule:
The blood levels and effects of ticagrelor may be greatly increased when combined with I-Tyza SB 100 Capsule.

How to manage the interaction:
I-Tyza SB 100 Capsule and ticagrelor may interact, however if prescribed by a physician, they can be used together. While receiving therapy, you should consult a doctor if you develop any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Without consulting a doctor, never stop taking any medication.
ItraconazoleErgotamine
Critical
How does the drug interact with I-Tyza SB 100 Capsule:
The blood levels and effects of ergotamine may be greatly increased when combined with I-Tyza SB 100 Capsule.

How to manage the interaction:
Ergotamine and I-Tyza SB 100 Capsule may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you experience a severe headache, shortness of breath, blurred vision, confusion, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of the fingers or toes, pale or cold skin, or chest pain or tightness. Without first consulting your doctor, never stop taking medicines.
ItraconazoleSolifenacin
Critical
How does the drug interact with I-Tyza SB 100 Capsule:
The blood levels and effects of solifenacin may be greatly increased when combined with I-Tyza SB 100 Capsule.

How to manage the interaction:
Solifenacin and I-Tyza SB 100 Capsule may interact, however, if recommended by a physician, they are safe to consume. Consult a doctor if you feel sleepy, or uneasy, have an irregular heartbeat, have blurry vision, have trouble urinating, have a dry mouth, a headache, have digestive problems, or have constipation. Without consulting a doctor, never stop taking any medication.
ItraconazoleFelodipine
Critical
How does the drug interact with I-Tyza SB 100 Capsule:
The blood levels and effects of felodipine may be considerably increased by taking I-Tyza SB 100 Capsule together with felodipine.

How to manage the interaction:
Although there is a possible interaction between felodipine and I-Tyza SB 100 Capsule, they can be taken if prescribed by a doctor. Consult a physician if you have an irregular heartbeat, Edema (accumulation of fluid in hands or legs), or abnormally low blood pressure. Without first consulting a doctor, never stop taking medicines.
ItraconazoleNisoldipine
Critical
How does the drug interact with I-Tyza SB 100 Capsule:
The blood levels and effects of nisoldipine may be greatly increased when used with I-Tyza SB 100 Capsule.

How to manage the interaction:
Nisoldipine and I-Tyza SB 100 Capsule may interact, but if prescribed by a doctor, they can be used together. Consult a physician if you have symptoms that include an irregular heartbeat, accumulation of fluid in legs or hands, or abnormally low blood pressure. Without consulting a doctor, never stop taking any medication.
ItraconazoleCisapride
Critical
How does the drug interact with I-Tyza SB 100 Capsule:
The blood level of Cisapride may be significantly raised by combining Cisapride with I-Tyza SB 100 Capsule.

How to manage the interaction:
Despite the possibility of an interaction when cisapride and I-Tyza SB 100 Capsule are combined, they can be taken if a doctor prescribes them. Consult a doctor if you develop any side symptoms, such as fainting, lightheadedness, dizziness, or rapid or pounding heartbeats. Without consulting a doctor, never stop taking any medication. Note: Cisapride is no longer available in the market.
ItraconazoleSilodosin
Critical
How does the drug interact with I-Tyza SB 100 Capsule:
Coadministration of I-Tyza SB 100 Capsule with Silodosin can increase the blood levels and effects of Silodosin, which may lead to side effects including extremely low blood pressure and increased heart rate.

How to manage the interaction:
Taking I-Tyza SB 100 Capsule with Silodosin together is not recommended as it can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, or heart palpitation. Do not discontinue any medications without consulting a doctor.
ItraconazoleTolvaptan
Critical
How does the drug interact with I-Tyza SB 100 Capsule:
Co-administration of Tolvaptan and I-Tyza SB 100 Capsule may significantly raise Tolvaptan blood levels and effects.

How to manage the interaction:
There may be a possibility of interaction between Tolvaptan and I-Tyza SB 100 Capsule, but it can be taken if prescribed by a doctor. If you notice any of these signs -difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures, call a doctor right away. Do not stop using any medications without a doctor's advice.
ItraconazoleIsavuconazole
Critical
How does the drug interact with I-Tyza SB 100 Capsule:
The blood levels and effects of Isavuconazole may be significantly enhanced by taking I-Tyza SB 100 Capsule along with it.

How to manage the interaction:
Co-administration of Isavuconazole and I-Tyza SB 100 Capsule can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like nausea, vomiting, or diarrhoea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ItraconazoleMethylergometrine
Critical
How does the drug interact with I-Tyza SB 100 Capsule:
Co-administration of Methylergometrine and I-Tyza SB 100 Capsule may increase the blood levels of Methylergometrine.

How to manage the interaction:
Methylergometrine and I-Tyza SB 100 Capsule may interact, but if prescribed by a doctor, they can be used together. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Grapefruit juice: Avoid drinking grapefruit juice, as it can interfere with how your body processes I-Tyza Sb 100 Cap and increase the risk of side effects.
  • Full meals: I-Tyza Sb 100 Cap capsules require food in the stomach to be properly absorbed, whereas the oral solution should not be taken with food.
ITRACONAZOLE-100MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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ITRACONAZOLE-100MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consuming Grapefruit, Grapefruit juice with I-Tyza SB 100 Capsule may impair the absorption of I-Tyza SB 100 Capsule, resulting in decreased antifungal effects. Avoid consuming Grapefruit and grapefruit juice with I-Tyza SB 100 Capsule.

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Habit Forming

No

Therapeutic Class

[ANTIFUNGALS]

FAQs

I-Tyza Sb 100 Cap is used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. It works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby killing fungi and clearing the fungal infection.
You are not recommended to take I-Tyza Sb 100 Cap with simvastatin, as co-administration of these two medicines may cause muscle weakness, unexplained muscle pain or tenderness, dark-coloured urine, fever, or flu-like symptoms. However, please consult a doctor before using I-Tyza Sb 100 Cap with other medicines.
I-Tyza Sb 100 Cap may cause temporary or permanent hearing loss in some people. It is not necessary for everyone taking I-Tyza Sb 100 Cap to experience this adverse effect. However, if you notice any changes in hearing, stop taking I-Tyza Sb 100 Cap and consult a doctor immediately.
Yes, fungal infection is a contagious skin condition which spreads from one person to another through direct skin to skin contact or by contact with contaminated soil or surfaces and infected animals. Therefore, it is recommended to avoid close direct contact until the infection is clear and avoid sharing things with the infected person as it can also spread the infection.
You are not recommended to stop taking I-Tyza Sb 100 Cap without consulting your doctor as it may cause recurring infection. Therefore, take I-Tyza Sb 100 Cap for as long as your doctor has prescribed it, and if you experience any difficulty while taking I-Tyza Sb 100 Cap , please consult your doctor.
Inform your doctor if you are sexually active and discuss effective contraception methods. I-Tyza Sb 100 Cap may reduce the effectiveness of oral contraceptive pills. Thus, you are advised to use barrier methods of contraception like condoms, if you are taking I-Tyza Sb 100 Cap .
Inform the doctor about your detailed medical and surgical history, if you have liver, kidney or heart disease or fits and if you are pregnant, breastfeeding or planning pregnancy. Inform your doctor if you are taking any other medicines including supplements or herbal products as I-Tyza Sb 100 Cap may interact with other medicines. Also, let your doctor know if you are stopping any medicine.
I-Tyza Sb 100 Cap contains Itraconazole, an antifungal that works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, it causes the main components of fungal cells to leak out, kill fungi, and clear the fungal infection.
Yes, you should swallow the capsule whole with a glass of water. Do not crush, chew or break it.
The side effects of I-Tyza Sb 100 Cap include nausea, headache, diarrhoea, stomach pain, fatigue (overtiredness), back pain, cough, and sore throat. If these side effects persist or worsen, please consult your doctor.
If you have taken overdose of I-Tyza Sb 100 Cap , please consult your doctor immediately.
Store I-Tyza Sb 100 Cap at room temperature. Protect from light and moisture. Keep out of reach and sight of children.
It is best to avoid alcohol while taking I-Tyza Sb 100 Cap . Both alcohol and this medicine are processed by the liver, and combining them can increase your risk of liver damage. Talk to your doctor if you have concerns.
Nail infections take time to clear because the healthy nail must grow out. While the medicine starts working immediately to stop the fungus, you may not see the full results until several months after completing your treatment. Talk to your doctor if you do not notice improvement.
No, I-Tyza Sb 100 Cap is generally not recommended during pregnancy as it can harm an unborn baby. You should use effective birth control while taking this medicine and for several weeks after stopping it. Talk to your doctor for safer alternatives.
Yes, if you are taking the capsule form, you should take it with a full meal to help your body absorb it. If you are taking the oral solution, it should be taken on an empty stomach. Talk to your doctor or pharmacist to confirm which form you have.
Mild stomach upset or nausea is common when first starting this medicine. Taking the capsule form with a meal can help reduce these side effects. If your stomach issues are severe or do not go away, talk to your doctor.
Antacids and other acid reducers can stop your body from absorbing I-Tyza Sb 100 Cap capsules. You should take antacids at least 2 hours after taking this medicine, or take the capsules with an acidic beverage like cola. Talk to your pharmacist for specific advice.
Watch for warning signs of liver damage, including yellowing of your skin or eyes, unusually dark urine, pale stools, severe nausea, vomiting, or extreme fatigue. If you notice any of these symptoms, stop taking the medicine and call your doctor right away.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. U.S. Food and Drug Administration (FDA). 022484S000Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  2. MIMS Drug Reference Compendium. Itraconazole+ +oral Monograph. Singapore: MIMS; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Drugs.com Clinical Review Team. Itraconazole Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  4. Itraconazole Itraconazole. 1992. [Accessed on 29 Mar. 2019]Check here
  5. Kurn H, Wadhwa R Itraconazole. [Updated 2023 Apr 17]. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023Check here
  6. Janssen Pharmaceutical. SPORANOX® (itraconazole) Capsules: Prescribing Information [Internet]. Titusville (NJ): Janssen Pharmaceutical; [Accessed on 2025 Sep 16]Check here
  7. Thame Laboratories. Itraconazole 10 mg/ml Oral Solution: Summary of Product Characteristics [Internet]. High Wycombe: electronic Medicines Compendium (emc); [Accessed on 2025 Sep 16]Check here

Country of origin

India

Manufacturer/Marketer address

16Th Floor, Godrej Bkc, Plot €“ C, €Œg” Block, Bandra-Kurla Complex, Bandra (East), Mumbai €“ 400 051, India
Other Info - ITY0006
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