IB-Tib Capsule

Your doctor may prescribe IB-Tib Capsule to help manage certain blood cancers and related conditions:

• Chronic lymphocytic leukaemia (CLL): IB-Tib Capsule helps control abnormal B cells (a type of white blood cell) and slow the progression of the disease.
• Small lymphocytic lymphoma (SLL): This medicine helps control abnormal B cells that build up mainly in the lymph nodes and other tissues.
• Waldenström's macroglobulinaemia: It helps control abnormal B cells that produce excessive amounts of an abnormal protein in the blood.
• Other conditions: Ibrutinib may be used for other approved conditions depending on the country, treatment history, age, and individual clinical situation.

IB-Tib Capsule provides targeted treatment for certain blood cancers by blocking signals that abnormal B cells need to survive and grow.

• Helps control the disease: By reducing the growth and survival of abnormal cells, this medicine can slow disease progression.
• May reduce disease-related symptoms: As the condition responds to treatment, symptoms such as swollen lymph nodes, tiredness, or night sweats may improve.
• Provides an oral treatment option: Because the medicine is taken by mouth, treatment can usually be taken at home rather than requiring an intravenous infusion for each dose.
• Supports long-term disease management: Treatment may continue for as long as it remains effective and side effects can be safely managed.

• IB-Tib Capsule can be taken with or without food.
• It is usually recommended once daily; however, follow your doctor’s advice regarding the dosage and duration.
• Swallow the capsule as a whole with a glass of water.
• Do not break, chew or crush IB-Tib Capsule.

• Stay hydrated: Drink enough fluids, particularly if you develop diarrhoea, unless your doctor has advised you to limit fluids.
• Avoid grapefruit and Seville oranges: These fruits and their juices can increase the amount of ibrutinib in your blood and raise the risk of side effects.
• Reduce infection risk: Wash your hands regularly and avoid close contact with people who have contagious infections when possible.
• Protect yourself from bleeding: Use a soft toothbrush and take care when using sharp objects, particularly if you bruise or bleed easily.
• Eat a balanced diet: Choose a varied diet that supports your nutritional needs during treatment, and discuss significant appetite or weight changes with your healthcare team.

• Watch for bleeding: Tell your doctor about unusual bruising, prolonged bleeding, black stools, blood in your urine, or other signs of bleeding.
• Tell your doctor before procedures: Your doctor may advise stopping this medicine for a short period before and after surgery or dental procedures because of the risk of bleeding.
• Watch for infections: Consult your doctor if you develop fever, chills, persistent cough, or other signs of infection.
• Monitor your heart health: Tell your doctor promptly about a racing or irregular heartbeat, chest discomfort, fainting, or new shortness of breath.
• Check your blood pressure: This medicine can cause or worsen high blood pressure, so your doctor may monitor it during treatment.
• Discuss vaccinations: Ask your doctor before receiving any vaccine. Live vaccines are generally avoided during treatment.
• Use contraception as advised: Ibrutinib may harm an unborn baby. Follow your doctor's instructions about effective contraception during treatment and for the recommended period after your last dose.
• Keep your monitoring appointments: Your doctor may arrange blood tests and other checks to monitor blood cell counts, liver function, infections, bleeding risk, and other side effects.