Ibrunat Capsule 30's
MRP ₹8906
(Inclusive of all Taxes)
₹1335.9 Cashback (15%)
Know Your Delivery Time
Provide Delivery Location
Secure Payment
India's Most Trusted Pharmacy
Genuine Products
Composition :
Manufacturer/Marketer :
Consume Type :
Expires on or after :
Return Policy :
About Ibrunat Capsule
Ibrunat Capsule belongs to the group of anti-cancer medicines called protein kinase inhibitors used to treat the following blood cancers in adults- mantle cell lymphoma (cancer affecting the lymph nodes), chronic lymphocytic leukaemia (cancer affecting white blood cells and lymph nodes), and waldenström's macroglobulinaemia (cancer affecting white blood cells).
Ibrunat Capsule contains Ibrutinib, which works by blocking Bruton's tyrosine kinase, a protein in the body that helps cancer cells grow and survive. Thereby, it kills and reduces the number of cancer cells. It also slows down the worsening of cancer.
In some cases, Ibrunat Capsule may cause side effects such as nausea, vomiting, diarrhoea, constipation, indigestion, and fatigue. Most of these side effects may not require medical attention and resolve gradually over time. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.
Do not take Ibrunat Capsule if you are pregnant or breastfeeding. Consult the doctor immediately if you become pregnant during treatment with Ibrunat Capsule . This medicine is not recommended for children as safety and effectiveness have not been established. Inform the doctor about your health condition and medications to rule out any side effects/interactions.
Uses of Ibrunat Capsule
Ibrunat Capsule is used in the treatment of Mantle cell lymphoma, chronic lymphocytic leukaemia, and Waldenstramps macro globulinaemia. The detailed uses of Ibrunat Capsule are as follows:
- Mantle cell lymphoma (MCL): Ibrunat Capsule is used in adults who have received at least one prior therapy. It helps slow the progression of this aggressive form of non-Hodgkin lymphoma.
- Chronic lymphocytic leukemia (CLL):Ibrunat Capsule is used for patients with CLL, including those with the 17p deletion, a genetic mutation associated with poor prognosis.
- Waldenstramps macro globulinemia (WM): Ibrunat Capsule is also used to treat this rare type of non-Hodgkin lymphoma that affects B cells and leads to abnormal protein build up in the blood.
Have a query?
Directions for Use
- Ibrunat Capsule can be taken with or without food.
- It is usually recommended once daily; however, follow your doctor’s advice regarding the dosage and duration.
- Swallow the capsule as a whole with a glass of water.
- Do not break, chew or crush Ibrunat Capsule .
Key Benefits
Ibrunat Capsule belongs to the group of anti-cancer medicines called protein kinase inhibitors used to treat the following blood cancers in adults- mantle cell lymphoma, chronic lymphocytic leukaemia, and waldenström's macroglobulinaemia. This medicine may also be used to treat marginal zone lymphoma (cancer that begins in a type of white blood cells that normally fights infection) and chronic graft vs host disease (a complication of hematopoietic stem-cell transplant). Ibrunat Capsule contains Ibrutinib, which works by blocking Bruton's tyrosine kinase (a protein in the body that helps cancer cells grow and survive). Thereby, it kills and reduces the number of cancer cells. It also slows down the worsening of cancer.
How Ibrunat Capsule Works
Storage
- Inform your doctor about the medication you're taking and the UTI symptoms you're experiencing.
- Your doctor may adjust your medication regimen or consider alternative medications or dosages that may reduce the risk of UTIs.
- Drink plenty of water (at least 8-10 glasses a day) to help flush out bacteria. Avoid sugary drinks and caffeine, which can exacerbate UTI symptoms.
- Urinate when you feel the need rather than holding it in. This can help prevent bacterial growth and reduce the risk of UTIs.
- Consider cranberry supplements: Cranberry supplements may help prevent UTIs by preventing bacterial adhesion.
- Monitor UTI symptoms and report any changes to your doctor.
- If antibiotics are prescribed, take them as directed and complete the full course.
- Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
- Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
- Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
- Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
- If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
- In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
- Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
- If you experience severe bleeding or bruising, seek emergency medical attention immediately.
- Avoid taking raw fruits, nuts and vegetables.
- Do not share your personal things with others like toothbrushes.
- Clean the wounds and cuts using soap and water.
- Wash your hands thoroughly and frequently and maintain hygiene.
- Get a good quality of sleep.
- Include lean proteins like skinless poultry and fish.
- Choose whole grains and low-fat dairy products.
- Limit intake of fat and oil.
- Stay hydrated by drinking plenty of water.
- Restrict heavy sugar intake.
- Avoid red meat, processed foods, and refined sugar.
- Eat more fruits and vegetables.
- Stay hydrated by drinking plenty of water.
- Avoid rubbing your eyes, which can exacerbate the issue.
- Lubricate your eyes using artificial tears or eye drops.
- Wear sunglasses while you are out in the sun to protect your eyes from sun and wind.
- Avoid irritants like smoke, dust, and strong chemicals.
- Get enough rest and sleep to help your eyes recover.
What if I have taken an overdose of Ibrunat Capsule
Drug Warnings
Do not take Ibrunat Capsule if you are allergic to any of its components, if you are taking St. John's wort (herbal medicine) or if you are pregnant/breastfeeding. Inform the doctor if you have/had unusual bruising or bleeding, irregular heartbeat, heart failure, hepatitis B infection, liver problems, high blood pressure, kidney problems, or if you are due to undergo any surgery. Seek immediate medical attention if you experience symptoms of progressive multifocal leukoencephalopathy, a serious brain infection (trouble thinking, memory loss, sight loss, or difficulty walking), stroke (sudden confusion, numbness or weakness, trouble speaking, sight loss, loss of balance, or sudden severe headache), heart failure (breathlessness, difficulty breathing when lying down, weakness/tiredness, or swelling of the feet, ankles, or legs), rupture of the spleen (left abdominal pain, pain below the left rib cage or at the tip of left shoulder), infection (chills, fever, weakness, body aches, cold, flu symptoms, or confusion), or haemophagocytic lymphohistiocytosis, an inflammatory disorder (fever, bruising, swollen glands, or skin rash).
Drug-Drug Interactions
Drug-Drug Interactions
Login/Sign Up
Taking Fosamprenavir with Ibrunat Capsule may increase the levels of Ibrunat Capsule.
How to manage the interaction:
There may be a possibility of interaction between Ibrunat Capsule and Fosamprenavir, but it can be taken if prescribed by a doctor. However, if you experience paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhoea, sore throat, muscle aches, breathing difficulty, blood in coughing fluid, red or inflamed skin, body sores, pain or burning during urination, nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, irregular heart rhythm, consult a doctor. Do not discontinue any medications without a doctor's advice.
Co-administration of Ibrunat Capsule and Certolizumab can increase the risk of developing serious infections.
How to manage the interaction:
Although there is an interaction, Ibrunat Capsule can be taken with Certolizumab, if prescribed by the doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscle aches, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medications without a doctor's advice.
Taking Ibrunat Capsule with itraconazole may increase the levels of Ibrunat Capsule.
How to manage the interaction:
Although there is a possible interaction between Ibrunat Capsule and Itraconazole, they can be taken in case a doctor prescribes it. However, consult a doctor if you notice any of the following symptoms: paleness, tiredness, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhoea, sore throat, aches in the muscles, shortness of breath, blood in the phlegm, red or irritated skin, body sores, or pain or burning when urinating, nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without a doctor's advice.
Co-administration of Ibrunat Capsule and Rivaroxaban can increase the risk of bleeding problems.
How to manage the interaction:
Co-administration of Ibrunat Capsule and Rivaroxaban can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Co-administration of Ibrunat Capsule with Tirofiban can increase the risk of bleeding leading to serious blood loss.
How to manage the interaction:
Taking Ibrunat Capsule with Tirofiban together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
Co-administration of Ibrunat Capsule with Alteplase can increase the risk of bleeding.
How to manage the interaction:
Taking Ibrunat Capsule with Alteplase together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Co-administration of Enzalutamide may decrease the blood levels of Ibrunat Capsule, which may make Ibrunat Capsule less effective in treating your condition.
How to manage the interaction:
Although taking Enzalutamide and Ibrunat Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
Co-administration of Naproxen and Ibrunat Capsule can increase the risk or severity of bleeding.
How to manage the interaction:
Taking Naproxen and Ibrunat Capsule together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without consulting a doctor.
Taking Ibrunat Capsule with Clarithromycin may increase the levels of Ibrunat Capsule.
How to manage the interaction:
Although there is a possible interaction, Clarithromycin can be taken with Ibrunat Capsule if prescribed by the doctor. However, if you experience paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, blood in coughing fluid, red or inflamed skin, body sores, pain or burning during urination, nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, irregular heart rhythm, consult a doctor. Do not discontinue the medication without consulting a doctor.
When Ibrunat Capsule and Abciximab are taken together, there is a chance that bleeding and haemorrhage risk or severity will rise.
How to manage the interaction:
Taking Abciximab with Ibrunat Capsule together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness, consult a doctor. Do not discontinue any medications without a doctor's advice.
Drug-Food Interactions
Drug-Food Interactions
Login/Sign Up
Grapefruit Juice, Grapefruit, St. John’S Wort
How to manage the interaction:
Consumption of grape fruit or its products, St. John’S Wort during Ibrunat Capsule treatment may lead to an interaction. Avoid consumption of grape fruit or its products, St. John’S Wort while on therapy with Ibrunat Capsule.
Diet & Lifestyle Advise
- Eat a healthy diet and exercise regularly to maintain proper weight.
- Avoid smoking and alcohol consumption.
- Include vegetables and fruits in your diet.
- Avoid fast food, fried food, processed meats, refined carbs and added sugar.
- Get optimal sleep; rest well.
- Drink enough water.
Habit Forming
Therapeutic Class
All Substitutes & Brand Comparisons
RX
Ibrumed 140 mg Capsule 30's
Medicamen Biotech Ltd
₹303.5
(₹10.12 per unit)
95% CHEAPERRX
Out of StockImbruvica 140Mg Capsule 90'S
Johnson & Johnson Pvt Ltd
₹3644
(₹35.63 per unit)
85% CHEAPERRX
Out of StockBdbrut Capsule 30's
BDR Pharmaceuticals Internationals Pvt Ltd
₹7200
(₹196.8 per unit)
19% CHEAPER
Alcohol
Safe if prescribed
It is not known if alcohol affects Ibrunat Capsule . However, avoid consumption of alcohol while on treatment with Ibrunat Capsule as it may worsen your condition.
Pregnancy
Consult your doctor
Ibrutinib belongs to pregnancy category D. Ibrunat Capsule should not be used during pregnancy. Use effective contraception and avoid pregnancy during treatment with Ibrunat Capsule .
Breast Feeding
Consult your doctor
Avoid breastfeeding while taking Ibrunat Capsule .
Driving
Safe if prescribed
Ibrunat Capsule may cause dizziness and tiredness. Do not drive or operate machinery if you experience any side effects that might lessen your ability to do so.
Liver
Consult your doctor
Avoid taking Ibrunat Capsule if you have moderate or severe baseline liver impairment. Dose adjustment may be needed in patients with mild liver impairment. If you have a history of liver disease, inform the doctor.
Kidney
Consult your doctor
If you have a history of kidney disease, inform your doctor before taking Ibrunat Capsule .
Children
Safe if prescribed
Ibrunat Capsule is not recommended for children as safety and effectiveness have not been established.
Heart
Take Ibrunat Capsule with caution, especially if you have a history of heart diseases/conditions. The dose may be adjusted by your doctor as required.
Geriatrics
Consult your doctor
Ibrunat Capsule should be used with caution in elderly patients. Please consult your doctor before use.
FAQs
Ibrunat Capsule is used to treat Mantle cell lymphoma, chronic lymphocytic leukaemia, and Waldenstr’s macroglobulinaemia.
Ibrunat Capsule works by blocking the action of an abnormal protein that helps cancer cells multiply. Thereby, it stops the spread of cancer cells.
Ibrunat Capsule may make you bleed more easily. Therefore, consult the doctor if you are taking blood thinner medicines (heparin, warfarin), NSAIDs (aspirin, ibuprofen, naproxen), or supplements that may increase the risk of bleeding (flaxseed, vitamin E, fish oil).
Ibrunat Capsule may affect the heart, especially if you already have heart diseases like heart failure, heart rhythm problems, diabetes, high blood pressure, or are of advanced age. Consult the doctor instantly if you experience symptoms of heart failure like breathlessness, difficulty breathing when lying down, weakness/tiredness, or swelling of the feet, ankles, or legs.
Country of origin
Manufacturer/Marketer address
Disclaimer
Author Details
