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Imiren 0.5 gm Injection 1's is used to treat severe bacterial infections of the lungs, heart, bladder, skin, kidneys, bones, joints, blood, stomach and female reproductive organs. Imiren 0.5 gm Injection 1's may also be used in the management of patients with low white blood cell count who have a fever, which is suspected to be due to bacterial infection. Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. Imiren 0.5 gm Injection 1's does not work against infections caused by the virus, including cold and flu.
Imiren 0.5 gm Injection 1's is a combination of two drugs, namely: Cilastatin (dehydropeptidase inhibitor) and Imipenem (antibacterial). Cilastatin inhibits the dehydropeptidase enzyme, which causes the breakdown of Imipenem, thereby helps imipenem to stay active for a longer duration. Imipenem prevents the formation of the bacterial protective covering, which is necessary for the survival of the bacteria. Together, Imiren 0.5 gm Injection 1's helps to treat bacterial infections.
Imiren 0.5 gm Injection 1's will be administered by a healthcare professional; do not self-administer. In some cases, Imiren 0.5 gm Injection 1's may cause common side effects such as nausea, vomiting, diarrhoea, swelling, and redness at the site of injection. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Consult your doctor if you are pregnant or breastfeeding. Imiren 0.5 gm Injection 1's may cause dizziness, so drive with caution. Avoid alcohol consumption as it might cause increased dizziness and sleepiness. Imiren 0.5 gm Injection 1's should not be given to children below one year or those who weigh below 30kg with kidney problems. Imiren 0.5 gm Injection 1's is not recommended in paediatric patients with CNS infections due to the risk of seizures. Keep your doctor informed about your health condition and medications to rule out any unpleasant side effects.
Imiren 0.5 gm Injection 1's is used in the treatment of Severe bacterial infections. The detailed use of Imiren 0.5 gm Injection 1's is as follows:
Imiren 0.5 gm Injection 1's is a combination of two drugs, namely: Cilastatin (dehydropeptidase inhibitor) and Imipenem (antibacterial). Imiren 0.5 gm Injection 1's is used to treat severe bacterial infections of the lungs, heart, bladder, skin, kidneys, bones, joints, blood, stomach, and female reproductive organs. Imiren 0.5 gm Injection 1's may also be used in the management of patients with low white blood cell count who have a fever, which is suspected to be due to bacterial infection. Cilastatin inhibits the dehydropeptidase enzyme, which causes the breakdown of Imipenem, thereby helps imipenem to stay active for a longer duration. Imipenem prevents the formation of the bacterial protective covering, which is necessary for the survival of the bacteria. Together, Imiren 0.5 gm Injection 1's helps to treat bacterial infections. Imipenem is a broad-spectrum antibiotic that is effective against a wide range of aerobic and anaerobic bacteria.
Caution
Avoid alcohol consumption as it might cause increased dizziness and sleepiness.
Caution
Please consult your doctor if you are pregnant or planning for pregnancy. Your doctor will prescribe Imiren 0.5 gm Injection 1's only if the benefits outweigh the risks.
Caution
Imiren 0.5 gm Injection 1's may pass into breast milk. Please consult your doctor if you are breastfeeding; your doctor will decide if Imiren 0.5 gm Injection 1's can be given to breastfeeding mothers or not.
Caution
Imiren 0.5 gm Injection 1's may cause dizziness and sleepiness. Avoid driving or operating machinery unless you are alert.
Caution
Dose adjustment may be needed. Please consult your doctor if you have liver impairment/liver disease.
Caution
Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease.
Caution
Imiren 0.5 gm Injection 1's should not be given to children below one year or those who weigh below 30kg with kidney problems. Imiren 0.5 gm Injection 1's is not recommended in paediatric patients with CNS infections due to the risk of seizures.
Caution
Imiren 0.5 gm Injection 1's should be administered with caution, especially if you have a history of heart problems. Please inform your doctor about any existing heart problems before receiving Imiren 0.5 gm Injection 1's.
Caution
Imiren 0.5 gm Injection 1's should be administered with caution in elderly patients due to an increased risk of side effects. Dose adjustment may be required based on their health condition.

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Do not take Imiren 0.5 gm Injection 1's if you are allergic to any of its components. Inform your doctor if you have an allergy to antibiotics, colitis, gastrointestinal disease, urinary/kidney problems, CNS disorders, seizures/fits, or liver problems. Consult your doctor if you are pregnant or breastfeeding. Avoid alcohol consumption as it might cause increased dizziness and sleepiness. Imiren 0.5 gm Injection 1's should not be given to children below one year or those who weigh below 30kg with kidney problems. Imiren 0.5 gm Injection 1's is not recommended in paediatric patients with CNS infections due to the risk of seizures. Imiren 0.5 gm Injection 1's may cause dizziness and sleepiness, so drive with caution.
Drug-Drug Interactions: Imiren 0.5 gm Injection 1's may interact with anti-viral (Ganciclovir), uricosurics (Probenecid), anti-epileptic (Valproic acid, Divalproex sodium), blood thinner (warfarin).
Drug-Food Interactions: No interactions found/established.
Drug-Disease Interactions: Inform your doctor if you have colitis (inflammation in the lining of the colon), CNS disorders, hemodialysis, kidney or liver dysfunction.
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Imiren 0.5 gm Injection 1's is used to treat severe bacterial infections of the lungs, heart, bladder, skin, kidneys, bones, joints, blood, stomach and female reproductive organs.
Imiren 0.5 gm Injection 1's is a combination of two drugs, namely: Cilastatin and Imipenem. Cilastatin inhibits the dehydropeptidase enzyme, which causes the breakdown of Imipenem, thereby helps imipenem to stay active for a longer duration. Imipenem prevents the formation of the bacterial protective covering, which is necessary for the survival of the bacteria. Together, Imiren 0.5 gm Injection 1's helps to treat bacterial infections.
Diarrhoea might be a side-effect of Imiren 0.5 gm Injection 1's. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience prolonged diarrhoea with abdominal pain, consult your doctor. Do not take anti-diarrheal medicine on your own.
Concomitant administration of Probenecid (used to treat gout and hyperuricemia) along with Imiren 0.5 gm Injection 1's is not recommended as it might result in an increase of plasma levels and half-life of Imipenem.
Ganciclovir (anti-viral) should not be co-administered along with Imiren 0.5 gm Injection 1's unless benefits outweigh the risks as generalised seizures have been reported when taken together.
Imiren 0.5 gm Injection 1's may cause changes in urine colour and amount of urine. Do not worry and consult your doctor if you have any concerns regarding this.
Imiren 0.5 gm Injection 1's may rarely cause thrush or candidiasis, which is a fungal infection occurring due to the overgrowth of yeast-like fungus in the mouth or throat. Regularly rinse your mouth with water to prevent the growth of fungus.
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