Indofos-150Mg Tablet 1'S
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About Indofos-150Mg Tablet
Indofos-150Mg Tablet is used to prevent post-menopausal osteoporosis. It is indicated in adults for the prevention of skeletal events such as pathological fractures and bone complications requiring surgery or radiotherapy in patients with bone metastases or breast cancer.
Indofos-150Mg Tablet contains 'Ibandronic acid', which suppresses the activity of osteoclasts and makes the bone stronger. It lowers the risk of getting a fracture and reduces pain in the bones. Indofos-150Mg Tablet may reverse bone loss by increasing bone mass and stopping more bone loss.
Take Indofos-150Mg Tablet exactly as prescribed by the doctor. In some cases, Indofos-150Mg Tablet may cause side effects like heartburn, muscle pain, indigestion, headache, and nausea. Most of these side effects of Indofos-150Mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, consult your doctor.
Do not lie down for 60 minutes after taking Indofos-150Mg Tablet, and avoid eating your first food of the day for at least 60 minutes after taking Indofos-150Mg Tablet.Consult your doctor if you are pregnant or breastfeeding. Indofos-150Mg Tablet is not recommended for children below 18 years as safety and effectiveness have not been established.
Uses of Indofos-150Mg Tablet
Indofos-150Mg Tablet is used in the treatment of osteoporosis, a condition characterized by weakened bones and an increased risk of fractures. The detailed uses of Indofos-150Mg Tablet are as follows:
- Treatment of osteoporosis: Indofos-150Mg Tablet helps strengthen bones and reduce the likelihood of spine, hip, and other bone fractures in individuals with osteoporosis, particularly postmenopausal women.
- Bone resorption inhibition: Indofos-150Mg Tablet works by inhibiting the activity of osteoclasts (bone-resorbing cells), thereby slowing down the breakdown of bone and maintaining bone density.
- Postmenopausal osteoporosis management: Indofos-150Mg Tablet is used for the prevention and treatment of osteoporosis in postmenopausal women who are at high risk of fractures.
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Directions for Use
- Indofos-150Mg Tablet should be taken on an empty stomach as food may lower its absorption. It should be taken after you first get up for the day, at least 6 hours after you last had anything to eat or drink except water.
- It is usually to be taken once a month; however, follow your doctor’s advice regarding the dosage and duration.
- Swallow Indofos-150Mg Tablet as a whole with a full glass of water.
- Do not crush, chew, or break it.
- Avoid lying down, eating, or drinking (except water) for 60 minutes after taking Indofos-150Mg Tablet.
Medicinal Benefits
Indofos-150Mg Tablet belongs to a group of medications called 'bisphosphonates' used to prevent post-menopausal osteoporosis. It is indicated in adults for the prevention of skeletal events such as pathological fractures and bone complications requiring surgery or radiotherapy in patients with bone metastases or breast cancer. Indofos-150Mg Tablet may also be used to lower hypercalcemia (higher levels of calcium in the blood). Indofos-150Mg Tablet contains 'Ibandronic acid', which suppresses the activity of osteoclasts and makes the bone stronger. It lowers the risk of getting a fracture and reduces pain in the bones. Indofos-150Mg Tablet may reverse bone loss by increasing bone mass and stopping more bone loss.
How Indofos-150Mg Tablet Works
Storage
- Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
- Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
- Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
- Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
- Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
- Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
- Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
- Talk to your doctor about your back pain and potential medication substitutes or dose changes.
- Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
- To lessen the tension on your back, sit and stand upright and maintain proper posture.
- To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
- Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
- Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
- To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
- Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
- Back discomfort can worsen by bending, twisting, and heavy lifting.
- Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
- Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
- Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
- Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
- Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
- Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
- If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
- Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
- Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
- Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
- Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
- Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
- Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
- Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
- Drink water or other clear fluids.
- To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
- Include bland foods like rice, toast, crackers, and rice in your diet.
- Avoid lying down immediately after eating as it may cause indigestion or heartburn.
- Avoid acidic and spicy food as it may cause indigestion.
- Report to Your Doctor: Inform your doctor about the muscle pain, as they may need to adjust your medication.
- Stretch Regularly: Gentle stretching can help relieve muscle pain and stiffness.
- Stay Hydrated: Adequate water intake supports muscle health by removing harmful substances and maintaining proper muscle function.
- Warm or Cold Compresses: Apply cold or warm compresses to the affected area to reduce pain and inflammation.
- Rest and Relaxation: Adequate rest helps alleviate muscle strain, while relaxation techniques like deep breathing and meditation can soothe muscle tightness, calm the mind, and promote relief from discomfort.
- Gentle Exercise: Participate in low-impact activities, such as yoga or short walks, to improve flexibility, reduce muscle tension, and alleviate discomfort.
- Consult a physician: If your symptoms don't improve or get worse, go to the doctor for help and guidance.
- Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
- Divide your daily food intake into smaller, more frequent meals to reduce nausea.
- Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
- Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
- Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
- Use ginger (tea, ale, or candies) to help relieve nausea.
- Get adequate rest and also avoid strenuous activities that can worsen nausea.
- Talk to your doctor about taking anti-nausea medication if your nausea is severe.
- Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
What if I have taken an overdose of Indofos-150Mg Tablet
Drug Warnings
Do not take Indofos-150Mg Tablet if you are allergic to any of its components, have problems with the oesophagus, cannot sit or stand upright for at least 60 minutes, or have low calcium levels in the blood. Inform your doctor if you have problems with swallowing, stomach or digestive problems, malabsorption syndrome, kidney or liver problems, or if you plan to have teeth removal or dental surgery. Consult your doctor if you are pregnant or breastfeeding. Indofos-150Mg Tablet may cause problems with the oesophagus, low blood calcium levels, bone, joint, or muscle pain, osteonecrosis (severe jaw bone problems), and unusual thigh bone fractures. Keep your doctor informed about your health condition and medications to rule out any interactions/side effects.
Drug-Drug Interactions
Drug-Drug Interactions
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Taking Tacrolimus and Indofos-150Mg Tablet together may increase the risk of kidney problems.
How to manage the interaction:
Although taking Tacrolimus and Indofos-150Mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
Co-administration of Deferasirox with Indofos-150Mg Tablet (oral form) may raise your chance of experiencing gastrointestinal (stomach & intestine) bleeding and ulcers.
How to manage the interaction:
Co-administration of Indofos-150Mg Tablet with Deferasirox can result in an interaction, but it can be taken if a doctor has advised it. If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's essential to consult a doctor. Do not stop using any medications without a doctor's advice.
Co-administration of Sirolimus and Indofos-150Mg Tablet may cause an increase in the risk or severity of kidney damage.
How to manage the interaction:
Although taking Indofos-150Mg Tablet and Sirolimus together may lead to an interaction, it can be taken if a doctor has suggested it. However, if you experience symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, pain in the muscles, weakness, tiredness, dizziness, confusion, and irregular heart rhythm, consult a doctor. Do not stop using any medication without consulting a doctor.
Co-administration of Metrizamide with Indofos-150Mg Tablet may increase the risk or severity of kidney damage
How to manage the interaction:
Taking Indofos-150Mg Tablet with Metrizamide together can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
Co-administration of Iohexol with Indofos-150Mg Tablet may increase the risk of kidney damage.
How to manage the interaction:
There may be a possibility of interaction between Indofos-150Mg Tablet and Iohexol, but it can be taken if prescribed by a doctor. However, contact a doctor immediately if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
Co-administration of Cidofovir with Indofos-150Mg Tablet can increase the risk of kidney problems.
How to manage the interaction:
Although taking Indofos-150Mg Tablet and Cidofovir together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
Co-administration of Tenofovir alafenamide with Indofos-150Mg Tablet can increase the risk of kidney damage.
How to manage the interaction:
Taking Indofos-150Mg Tablet with Tenofovir alafenamide together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, pain in the muscles, weakness, tiredness, dizziness, confusion, and irregular heart rhythm, consult a doctor. Do not stop using any medications without consulting a doctor.
Co-administration of Human immunoglobulin with Indofos-150Mg Tablet may raise the risk of kidney problems.
How to manage the interaction:
Although there is a possible interaction between Human immunoglobulin and Indofos-150Mg Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
Drug-Food Interactions
Drug-Food Interactions
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Diet & Lifestyle Advise
- Eat a balanced diet rich in calcium and vitamin D.
- Avoid smoking and heavy alcohol consumption.
- Do walking, weight-bearing, and strength-training exercises.
- Include fresh fruits, vegetables, and whole grains in your diet.
- Limit your intake of caffeine.
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Alcohol
Caution
It is not known if alcohol affects Indofos-150Mg Tablet. Please consult your doctor.
Pregnancy
Caution
Indofos-150Mg Tablet belongs to pregnancy category C. Consult your doctor if you are pregnant. Your doctor will prescribe Indofos-150Mg Tablet only if the benefits outweigh the risks.
Breast Feeding
Caution
It is not known if Indofos-150Mg Tablet passes into breast milk. Consult your doctor before taking this medicine if you are breastfeeding.
Driving
Safe if prescribed
Indofos-150Mg Tablet has no or negligible influence on the ability to drive.
Liver
Caution
Please consult your doctor before taking Indofos-150Mg Tablet if you have a liver impairment or any concerns regarding this.
Kidney
Caution
Indofos-150Mg Tablet is not recommended for people with severe renal impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Children
Unsafe
Indofos-150Mg Tablet is not recommended for children below 18 years as safety and effectiveness have not been established.
Heart
Please consult your doctor if you have any concerns regarding the usage of Indofos-150Mg Tablet in heart patients.
Geriatrics
Consult your doctor
Please consult a doctor before administering Indofos-150Mg Tablet to geriatric patients. Your doctor will prescribe Indofos-150Mg Tablet if the benefits outweigh the risks.
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Reference
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/021455s019lbl.pdf
- https://www.ema.europa.eu/en/documents/product-information/ibandronic-acid-teva-epar-product-information_en.pdf
- https://medikamio.com/en-gb/drugs/ibandronic-acid-teva-150-mg-film-coated-tablets/pil
- https://www.nhs.uk/ipgmedia/National/Macmillan%20Cancer%20Support/assets/Ibandronicacid(CB).pdf
