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Indoiv Injection is used to close patent ductus arteriosus (PDA) in premature babies. It works by inhibiting prostaglandin production, which keeps the ductus arteriosus open. As a result, the ductus arteriosus contracts and closes, improving blood flow to the lungs and reducing the risk of complications such as pulmonary hypertension and heart failure. Indoiv Injection may cause side effects like bleeding problems, temporary decrease in urine production, and kidney function impairment.
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About Indoiv Injection
Indoiv Injection is used to close patent ductus arteriosus (PDA) in premature babies. Patent ductus arteriosus is a congenital heart defect where the ductus arteriosus, a blood vessel connecting the aorta and pulmonary artery, fails to close after birth. This causes excessive blood flow to the lungs, increased pressure in the pulmonary arteries, and strain on the heart. Symptoms include shortness of breath, fatigue, poor feeding, and failure to thrive (fail to grow and develop normally).
Indoiv Injection contains Indomethacin. It works by inhibiting prostaglandin production, specifically prostaglandin E2 (PGE2), which keeps the ductus arteriosus open. By blocking PGE2, the ductus arteriosus contracts and closes, allowing blood to flow normally to the lungs, effectively reducing the risk of complications and improving lung function.
The dose and duration of treatment with Indoiv Injection will be determined by your doctor based on your child’s medical condition. Your child may experience some common side effects like bleeding problems, temporary decrease in urine production, and kidney function impairment, which will be closely monitored by your child's doctor.
Before giving Indoiv Injection to your baby, it's essential to inform your pediatrician about any medication or food allergies, pre-existing medical conditions such as kidney or liver disease, heart disease, or high blood pressure, and any current infections. This is crucial, as Indoiv Injection may mask infection symptoms, potentially leading to delayed diagnosis or underestimation of severity, ensuring your pediatrician can provide the best possible care for your baby.
Uses of Indoiv Injection
Indoiv Injection is used to close the patent ductus arteriosus (PDA) in premature babies. The detailed use of Indoiv Injection is as follows:

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Directions for Use
Medicinal Benefits
Indoiv Injection provides several medicinal benefits, including the effective closure of Patent Ductus Arteriosus (PDA) in premature babies, reduction of prostaglandin production, and improved lung function. Additionally, it provides pain relief, anti-inflammatory effects, and fever reduction. By treating PDA, Indoiv Injection helps prevent complications such as respiratory distress, making it a crucial medication in neonatal care.
How Indoiv Injection Works
Storage
What if I have taken an overdose of Indoiv Injection
Drug Warnings
Inform your pediatrician about any medication or food allergies, pre-existing medical conditions such as kidney or liver disease, heart disease, or high blood pressure, and any current infections. Inform your child had bleeding disorders such as active intracranial hemorrhage or gastrointestinal bleeding, thrombocytopenia, coagulation defects, suspected or confirmed necrotizing enterocolitis, severe renal impairment, and congenital heart disease.
Drug-Drug Interactions
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Drug-Food Interactions
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Habit Forming
Therapeutic Class
Alcohol
Not applicable
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Pregnancy
Not applicable
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Breast Feeding
Not applicable
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Driving
Not applicable
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Liver
Caution
Before administering Indoiv Injection, please inform your pediatrician if your child has a history of liver impairments or problems.
Kidney
Caution
Before administering Indoiv Injection, please inform your pediatrician if your child has a history of kidney impairments or problems.
Children
Safe if prescribed
Indoiv Injection is generally safe when prescribed by a doctor, particularly in premature babies. Please consult your doctor for further information.
Heart
Indoiv Injection may increase the risk of heart problems. Therefore, please inform your doctor if you have any pre-existing heart problems before prescribing Indoiv Injection.
Geriatrics
Caution
Elderly patients may require caution and dose adjustments, as Indoiv Injection may increase the risk of side effects like confusion and drowsiness.
Indoiv Injection is specifically used to treat premature infants weighing between 500 and 1750 grams who have a hemodynamically significant patent ductus arteriosus (PDA). Its primary purpose is to close the PDA, a congenital heart defect that can cause significant health issues in premature babies.
Indoiv Injection works by inhibiting prostaglandin production, specifically prostaglandin E2 (PGE2), which keeps the ductus arteriosus open. By blocking PGE2, the ductus arteriosus contracts and closes, allowing blood to flow normally to the lungs, effectively reducing the risk of complications and improving lung function.
Indoiv Injection is contraindicated in neonates with certain medical conditions, including untreated infections, bleeding disorders such as active intracranial hemorrhage or gastrointestinal bleeding, thrombocytopenia, coagulation defects, suspected or confirmed necrotizing enterocolitis, severe renal impairment, and congenital heart disease requiring patency of the ductus arteriosus for pulmonary or systemic blood flow.
Your child may experience some common side effects like bleeding problems, temporary decrease in urine production, and kidney function impairment, which will be closely monitored by your child's doctor.
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