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compositionComposition:AXITINIB-1MG
prescription
Prescription Medicine
info
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Inlyta 1mg Tablet is used to treat Renal Cell Carcinoma. It contains Axitinib, which works by stopping the action of a tyrosine kinase enzyme that causes the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body. It also decreases the blood supply to cancer tumors to slow down the growth of the tumor. In this way, Inlyta 1mg Tablet stops the production, spread and growth of cancerous cells.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

AXITINIB-1MG

Manufacturer/Marketer :

Pfizer Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Inlyta 1mg Tablet

Inlyta 1mg Tablet is a targeted anticancer medicine used to treat advanced kidney cancer (renal cell carcinoma). It works by blocking proteins involved in the formation of new blood vessels that supply tumours, helping to slow or stop cancer growth and spread. This medicine is commonly prescribed alone or in combination with other anticancer therapies to improve disease control in patients with advanced renal cell carcinoma.

You will typically take Inlyta 1mg Tablet twice daily, approximately 12 hours apart. You can take this medication with or without food, but it is important to take it consistently at the same times each day. To support your body during treatment, your doctor may suggest making simple lifestyle changes, such as eating a low-sodium diet and staying well-hydrated to help manage potential side effects.

While taking Inlyta 1mg Tablet , you may experience common side effects like diarrhoea, high blood pressure, and feeling unusually tired. If you experience severe side effects, such as sudden chest pain, unusual bleeding, or severe abdominal pain, you must contact your healthcare provider immediately.

Do not take this if you have uncontrolled high blood pressure or are allergic to any of its ingredients. Before starting this treatment, talk to your doctor if you have a history of blood clots, heart problems, liver damage, bleeding issues, or thyroid conditions.

Certain medications, as well as smoking and drinking alcohol, can change how Inlyta 1mg Tablet works in your body. It is vital to consult your doctor if you are pregnant, breastfeeding, or planning a family, as this medication can harm an unborn baby. Elderly individuals should also talk to their doctor to ensure this medication is safe for them.

Uses of Inlyta 1mg Tablet

Inlyta 1mg Tablet is used to treat advanced kidney cancer (renal cell carcinoma).. The detailed uses of Inlyta 1mg Tablet are as follows:

  • Advanced Kidney Cancer: Inlyta 1mg Tablet is used to treat advanced renal cell carcinoma (kidney cancer) that has spread to other parts of the body, particularly after other initial treatments have stopped working.

Key Benefits

Inlyta 1mg Tablet helps treat advanced kidney cancer by slowing the growth and spread of cancer cells. With regular use as prescribed, it helps control disease progression, reduce tumour-related symptoms, and support better long-term treatment outcomes.

  • Helps Slow Cancer Progression: By targeting pathways that promote cancer cell growth, this medicine helps delay the progression of advanced kidney cancer and supports effective disease control.
  • Reduces Tumour-Related Symptoms: By slowing the growth or shrinking tumours, this medicine may help relieve pain, pressure, and other symptoms caused by cancer, improving overall comfort.
  • Supports Quality of Life: Effective disease control helps maintain energy levels, improve daily functioning, and allows many patients to continue their regular activities with greater comfort during treatment.
Side effects of Inlyta 1mg Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Consume more protein-rich foods and healthy fats like beans, avocados, cheese, nuts and lean meats to minimize appetite.
  • Prefer foods high in fiber to help feel full for a long time.
  • If you have decreased appetite, eat only when you are hungry.
  • Eat several small meals or snacks all day.
  • Try to take only small sips of fluids while eating.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Directions for Use

  • Inlyta 1mg Tablet can be taken with or without food as prescribed by your doctor.
  • It is recommended to take twice daily; however, follow your doctor’s advice regarding the dosage and duration.
  • Swallow the medicine as a whole with a glass of water.
  • Do not break, chew or crush Inlyta 1mg Tablet .

How Inlyta 1mg Tablet Works

Inlyta 1mg Tablet contains axitinib, which belongs to a group of medicines known as targeted therapies. It works by blocking specific proteins on the surface of cells that control the growth of blood vessels. Tumours need a constant blood supply to grow and spread throughout the body. By blocking these proteins, Inlyta 1mg Tablet helps cut off the blood supply to the kidney cancer cells, essentially starving them of the oxygen and nutrients they need to multiply.
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Alcohol

Caution

Limit alcohol consumption while taking Inlyta 1mg Tablet .

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Pregnancy

Unsafe

Inlyta 1mg Tablet is not recommended for use in pregnancy as it may cause embryo-fetal toxicity and harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before taking Inlyta 1mg Tablet . You should not become pregnant while you are taking Inlyta 1mg Tablet . Using effective birth control methods while on treatment with Inlyta 1mg Tablet is suggested.

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Breast Feeding

Caution

It is not known whether Inlyta 1mg Tablet passes into breastmilk. Hence, if you are breastfeeding, inform your doctor before taking Inlyta 1mg Tablet . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Unsafe

Inlyta 1mg Tablet may cause dizziness and visual disturbances in some patients. Hence, do not drive, operate machinery, or engage in any activity that needs clear vision until you are confident that you can do so safely while you are on treatment with Inlyta 1mg Tablet .

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Liver

Caution

If you have a pre-existing or a history of liver problems, tell your doctor before taking this medicine. Inlyta 1mg Tablet is known to cause elevated liver enzymes, which may be fatal. Hence, this medicine should be taken cautiously in patients with moderate liver impairment. Your doctor may suggest tests to monitor your liver function while on treatment with this medicine.

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Kidney

Caution

If you have a pre-existing or a history of kidney diseases, inform your doctor before taking Inlyta 1mg Tablet . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Inlyta 1mg Tablet is not recommended for use in children below 18 years of age as the safety and efficacy is not established.

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Heart

Consult your doctor

Please consult your doctor if you have any heart problems before taking Inlyta 1mg Tablet .

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Geriatrics

Consult your doctor

Please consult a doctor before administering Inlyta 1mg Tablet to geriatric patients. Your doctor will prescribe Inlyta 1mg Tablet if the benefits outweigh the risks.

What if I have taken an overdose of Inlyta 1mg Tablet

If you take too much of this medicine, seek immediate medical attention or contact a nearby hospital. Do not wait for symptoms of an overdose to appear.

Diet & Lifestyle Advise

  • Monitor your blood pressure daily and keep a log to share with your healthcare provider, as this medication commonly raises blood pressure.
  • Protect your hands and feet by wearing comfortable, well-fitting shoes and applying thick moisturising creams to prevent peeling or soreness.
  • Stay well-hydrated throughout the day by drinking plenty of water, which helps manage and prevent dehydration from diarrhoea.
  • Avoid eating grapefruit or drinking grapefruit juice, as these can increase the level of the drug in your body to unsafe levels.
health query

Have a query?

How Soon It Starts Working

The time required for Inlyta 1mg Tablet to start to work: The time required for Inlyta 1mg Tablet to show its action is not clinically established. The time for which the effects of Inlyta 1mg Tablet last: The duration of action for Inlyta 1mg Tablet is not clinically established.

What if you forget to take Inlyta 1mg Tablet

If you miss a dose of Inlyta 1mg Tablet , skip the missed dose and take your next dose at your regularly scheduled time. Do not take two doses at the same time to make up for a missed one. If you vomit after taking a dose, do not take an extra tablet; simply wait and take your next scheduled dose at the normal time.

Storage

• Store Inlyta 1mg Tablet tablets at room temperature, between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Inspect your tablets before taking them; do not take any tablet that is broken, chipped, or damp.
  • Make sure your doctor knows you are taking Inlyta 1mg Tablet before scheduling any surgery or dental procedures, as you may need to temporarily stop taking this medicine to allow wounds to heal properly.
  • Get your thyroid function checked regularly with blood tests, as this medicine can affect your thyroid hormone levels.
  • Keep a written record of your daily blood pressure readings so your doctor can adjust your blood pressure medications if necessary.

Drug-Drug Interactions

verifiedApollotooltip

  • Strong CYP3A4/5 inhibitors: Taking these medications (such as certain antibiotics or antifungals) alongside Inlyta 1mg Tablet can raise the amount of the drug in your body, increasing the risk of serious side effects.
  • Strong CYP3A4/5 inducers: Taking these medications (such as certain seizure medicines or tuberculosis treatments) can decrease the amount of Inlyta 1mg Tablet in your blood, making the treatment less effective.
AxitinibMitotane
Severe
AxitinibSaquinavir
Severe

Drug-Drug Interactions

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AxitinibMitotane
Severe
How does the drug interact with Inlyta 1mg Tablet:
Mitotane may decrease the blood levels of Inlyta 1mg Tablet, which may make Inlyta 1mg Tablet less effective in treating the condition.

How to manage the interaction:
Although taking Inlyta 1mg Tablet and Mitotane together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without talking to a doctor.
AxitinibSaquinavir
Severe
How does the drug interact with Inlyta 1mg Tablet:
When Inlyta 1mg Tablet is taken with Saquinavir, the body's ability to break down Inlyta 1mg Tablet may be reduced.

How to manage the interaction:
There may be a possibility of interaction between Inlyta 1mg Tablet and Saquinavir, but it can be taken if prescribed by a doctor. However, if you experience Chest pain or pressure, pain in the arms, back, neck, or jaw, swelling, shortness of breath, numbness or weakness on one side of the body, headache, vision changes, seizures, unusual bleeding or bruising, red or black stools, coughing up or vomiting blood or blood clots, and extreme stomach or abdominal pain, consult a doctor immediately. Do not stop using any medications without talking to a doctor.
AxitinibTroleandomycin
Severe
How does the drug interact with Inlyta 1mg Tablet:
Co-administration of Inlyta 1mg Tablet with troleandomycin may cause Inlyta 1mg Tablet blood levels to rise significantly, leading to an increased risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Inlyta 1mg Tablet and Troleandomycin, you can take these medicines together if prescribed by a doctor. However, if you experience high blood pressure, diarrhea, nausea, vomiting, constipation, decreased appetite, weight loss, rash, itching or peeling of skin on the hands and feet, chest pain or pressure, pain in the arms, back, neck or jaw, swelling, shortness of breath, numbness or weakness on one side of the body, headache, vision changes, seizures, unusual bleeding or bruising, red or black stools, coughing up or vomiting blood or blood clots, and severe stomach or abdominal pain, consult a doctor. Do not stop using any medications without a doctor’s advice.
AxitinibEfavirenz
Severe
How does the drug interact with Inlyta 1mg Tablet:
Efavirenz may decrease the blood levels of Inlyta 1mg Tablet, which may make Inlyta 1mg Tablet less effective in treating the condition.

How to manage the interaction:
Although there is a possible interaction between Inlyta 1mg Tablet and Efavirenz, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
AxitinibCobicistat
Severe
How does the drug interact with Inlyta 1mg Tablet:
When Inlyta 1mg Tablet is taken with Cobicistat, the body's ability to break down Inlyta 1mg Tablet is reduced.

How to manage the interaction:
There may be a possibility of interaction between Cobicistat and Inlyta 1mg Tablet, but it can be taken if prescribed by a doctor. However, if you experience Chest pain or pressure, pain in the arms, back, neck, or jaw, swelling, shortness of breath, numbness or weakness on one side of the body, headache, vision changes, seizures, unusual bleeding or bruising, red or black stools, coughing up or vomiting blood or blood clots, and extreme stomach or abdominal pain, seek immediate medical attention. Do not discontinue any medications without consulting a doctor.
AxitinibModafinil
Severe
How does the drug interact with Inlyta 1mg Tablet:
Coadministration of Modafinil with Inlyta 1mg Tablet may decrease the blood levels of Inlyta 1mg Tablet, which may make Inlyta 1mg Tablet less effective in treating the condition.

How to manage the interaction:
Although there is a possible interaction between Inlyta 1mg Tablet and Modafinil, you can take these medicines together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
AxitinibClotrimazole
Severe
How does the drug interact with Inlyta 1mg Tablet:
Taking Inlyta 1mg Tablet with clotrimazole can increase the effect of Inlyta 1mg Tablet.

How to manage the interaction:
Although taking Clotrimazole with Inlyta 1mg Tablet may result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
AxitinibAtazanavir
Severe
How does the drug interact with Inlyta 1mg Tablet:
When Inlyta 1mg Tablet is taken with Atazanavir, it can cause a decrease in the way the body processes Inlyta 1mg Tablet.

How to manage the interaction:
Although there is a possible interaction between Inlyta 1mg Tablet and Atazanavir, you can take these medicines together if prescribed by a doctor. However, if you experience chest pain or pressure, pain in the arms, back, neck, or jaw, swelling, shortness of breath, numbness or weakness on one side of the body, headache, vision changes, seizures, unusual bleeding or bruising, red or black stools, coughing up or vomiting blood or blood clots, and severe stomach or abdominal pain, seek immediate medical attention. Do not discontinue any medications without consulting a doctor.
AxitinibArmodafinil
Severe
How does the drug interact with Inlyta 1mg Tablet:
Armodafinil may reduce the blood levels of Inlyta 1mg Tablet, which may reduce the effect of Inlyta 1mg Tablet.

How to manage the interaction:
If you are supposed to take Armodafinil and Inlyta 1mg Tablet together, your doctor may adjust the dose or monitor you more frequently to safely use both medications. If your symptoms worsen or your condition changes, contact your doctor.
AxitinibNefazodone
Severe
How does the drug interact with Inlyta 1mg Tablet:
Co-administration of Inlyta 1mg Tablet with nefazodone may cause Inlyta 1mg Tablet blood levels to rise significantly, leading to an increased risk of side effects.

How to manage the interaction:
Taking Inlyta 1mg Tablet with Nefazodone together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience high blood pressure, diarrhea, nausea, vomiting, constipation, decreased appetite, weight loss, rash, itching or peeling of skin on the hands and feet, chest pain or pressure, pain in the arms, back, neck or jaw, swelling, shortness of breath, numbness or weakness on one side of the body, headache, vision changes, seizures, unusual bleeding or bruising, red or black stools, coughing up or vomiting blood or blood clots, and severe stomach or abdominal pain, consult a doctor. Do not stop using any medications without a doctor’s advice.

Drug-Food Interactions

verifiedApollotooltip
  • Grapefruit and grapefruit juice: May increase the risk of severe side effects by slowing down how your body breaks down the medication.
  • Smoking tobacco: Can decrease the amount of the medication in your body, which may reduce how well the drug works.
AXITINIB-1MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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AXITINIB-1MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consuming grapefruit or grapefruit juice might raise the medication's levels in the blood leading to side effects such as high blood pressure, diarrhea, nausea, vomiting, constipation, decreased appetite, weight loss, and rash, itching or peeling of skin on the hands and feet. Avoid consuming grapefruit or grapefruit juice during treatment with Inlyta 1mg Tablet.

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTINEOPLASTIC]

FAQs

No. Inlyta 1mg Tablet should not be used during pregnancy because it can seriously harm an unborn baby. It is also not recommended while breastfeeding. Do not take Inlyta 1mg Tablet if you are allergic to axitinib or any of its ingredients. Use effective contraception during treatment and for the period recommended by your doctor. If you are pregnant, planning a pregnancy, or think you may be pregnant, contact your doctor immediately.
Yes, you can take Inlyta 1mg Tablet with or without food. Try to be consistent with how you take it each day. Talk to your doctor or pharmacist if you need help planning your schedule.
If you throw up after taking your dose, do not take an extra dose. Simply wait and take your next dose at your regular scheduled time. Talk to your doctor or pharmacist if vomiting continues.
Some people may experience hair thinning or hair loss while taking Inlyta 1mg Tablet , though this is usually temporary. Talk to your doctor if you are concerned about hair changes.
While there is no direct interaction, alcohol can worsen side effects like dehydration, dizziness, and liver strain. Talk to your doctor or pharmacist before drinking alcohol during your treatment.
You should check your blood pressure regularly, often daily, especially during the first few weeks of starting Inlyta 1mg Tablet . Talk to your doctor if your blood pressure begins to rise.
Inlyta 1mg Tablet can interfere with how your body heals wounds. You may need to stop taking it before and after a planned surgery or dental work. Talk to your doctor for specific instructions.
No, Inlyta 1mg Tablet is a targeted therapy rather than traditional chemotherapy. It specifically blocks the signals and blood supply that cancer cells need to grow, rather than killing all fast-growing cells. Talk to your doctor for more details.

Disclaimer

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Country of origin

INDIA

Manufacturer/Marketer address

The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051
Other Info - INL0074
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