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  3. Inmeth 50 mg Suppositories 5's

Prescription drug
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Inmeth 50 mg Suppositories 5's, Pack of 5 SuppositoryS
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Inmeth 50 mg Suppositories is an NSAID (Non-Steroidal Anti-Inflammatory Drugs) medicine used to relieve pain, swelling, and stiffness caused by osteoarthritis, ankylosing spondylitis, acute gouty arthritis, bursitis and/or tendinitis, and rheumatoid arthritis This medicine inhibits cyclo-oxygenase (COX) enzymes and thus helps reduce pain. Common side effects include headache, dizziness, indigestion, rectal pain, application site reactions, and nausea.
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Composition :

INDOMETHACIN-50MG

Manufacturer/Marketer :

Hetero Healthcare Pvt Ltd

Consume Type :

RECTAL

Return Policy :

Not Returnable

Expires on or after :

About Inmeth 50 mg Suppositories

Inmeth 50 mg Suppositories belongs to the group of pain killers known as NSAID's (Non-Steroidal Anti-Inflammatory Drugs) used to relieve symptoms caused by osteoarthritis, ankylosing spondylitis, and rheumatoid arthritis such as stiffness, swelling and joint pain. Inmeth 50 mg Suppositories is also used to treat acute gouty arthritis and bursitis and/or tendinitis (painful shoulder).

Inmeth 50 mg Suppositories contains 'Indomethacin' that works by blocking the effect of chemical messengers known as cyclo-oxygenase (COX) enzymes. By blocking the effect of COX enzymes, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

You are advised to take Inmeth 50 mg Suppositories for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side effects such as headache, dizziness, indigestion, and nausea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

If you have had any recent heart surgery, do not use Inmeth 50 mg Suppositories as it may increase the risk of heart attack or stroke. Inmeth 50 mg Suppositories may also increase the chances of stomach ulcers and bleeding. Do not use Inmeth 50 mg Suppositories if you are pregnant or breastfeeding unless prescribed. Inmeth 50 mg Suppositories may cause dizziness, so drive with caution. Inmeth 50 mg Suppositories is not recommended for children below 14 years as safety and efficacy have not been established. Avoid consuming alcohol along with Inmeth 50 mg Suppositories as it could lead to increased dizziness; it might also increase the risk of stomach bleeding.

Uses of Inmeth 50 mg Suppositories

Inmeth 50 mg Suppositories is used in the treatment of Osteoarthritis, Ankylosing spondylitis, and Rheumatoid arthritis. The detailed uses of Inmeth 50 mg Suppositories are as follows:<br/>• Osteoarthritis: Inmeth 50 mg Suppositories helps to relieve osteoarthritis pain, tenderness, swelling, and stiffness caused by joint lining breakdown.<br/>• Rheumatoid Arthritis: Inmeth 50 mg Suppositories manages rheumatoid arthritis pain, inflammation, and joint damage associated with joint lining swelling.<br/>• Ankylosing Spondylitis: Inmeth 50 mg Suppositories relieves ankylosing spondylitis pain, stiffness, and inflammation in the spine and other affected joints.<br/>• Acute Gouty Arthritis: Inmeth 50 mg Suppositories treats severe joint pain and swelling caused by a buildup of certain substances in the joints.<br/>• Bursitis: Inmeth 50 mg Suppositories relieves bursitis pain and inflammation in the shoulder joint caused by swelling of the fluid-filled sac.<br/>• Tendinitis: Inmeth 50 mg Suppositories manages tendinitis pain and inflammation of the tissue connecting muscle to bone.<br/>

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Directions for Use

• It is advised to use Inmeth 50 mg Suppositories 2 to 4 times daily; however, follow your doctor's advice regarding the dosage and duration.• Lie down on your left side and raise your right knee to the chest. Remove the wrapper and insert the pointed end of the suppository into the rectum. Hold it in place for a few moments.• Remain lying down for 5 minutes to prevent the suppository from coming out.

Medicinal Benefits

Inmeth 50 mg Suppositories belongs to the group of pain killers known as NSAIDs (Non-Steroidal Anti-Inflammatory Drugs). Inmeth 50 mg Suppositories is used to relieve symptoms caused by osteoarthritis, ankylosing spondylitis, and rheumatoid arthritis such as stiffness, swelling and joint pain. Inmeth 50 mg Suppositories is also used to treat acute gouty arthritis and bursitis and/or tendinitis (painful shoulder). Inmeth 50 mg Suppositories works by blocking the effect of chemical messengers known as cyclo-oxygenase (COX) enzymes. By blocking the effect of COX enzymes, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

How Inmeth 50 mg Suppositories Works

Inmeth 50 mg Suppositories contains 'Indomethacin' that works by blocking the effect of chemical messengers known as cyclo-oxygenase (COX) enzymes. By blocking the effect of COX enzymes, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Storage

• Store in a cool and dry place away from sunlight.• Keep Inmeth 50 mg Suppositories out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Inmeth 50 mg Suppositories
  • Maintain a healthy diet with fruits, whole grains, and vegetables.
  • Include easy-to-digest and antioxidant-rich food in your diet.
  • Drink plenty of water and unsweetened liquids.
  • Limit sugary foods, alcohol, refined carbs and fried foods.
  • High levels of liver enzymes need immediate medical attention.
  • Watch your diet and consume low-fat foods, like green leafy vegetables, fish, whole grains, nuts, etc.
  • Regularly do strengthening exercises to control your cholesterol levels.
  • Avoid drinking alcohol as it can affect your liver.
  • Focus on losing weight as it can help control cholesterol and maintain liver enzymes.
  • Practice yoga and meditation to improve liver functioning and overall health.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

What if I have taken an overdose of Inmeth 50 mg Suppositories

Use Inmeth 50 mg Suppositories as prescribed. Overdose may cause symptoms like confusion about identity, place, and time, severe headache and unusual drowsiness, dullness, or a feeling of sluggishness. Seek medical help if an overdose is suspected.

Drug Warnings

Do not take Inmeth 50 mg Suppositories if you are allergic to Inmeth 50 mg Suppositories. Inform your doctor if you are due to undergo heart bypass surgery (CABG) or graft surgery, have severe heart failure, history of proctitis (inflammation of the lining of the rectum) or recent rectal bleeding, or have suffered bleeding problems such as bleeding from the stomach or bowels while taking any pain killers or if you have liver or kidney problems. Do not take Inmeth 50 mg Suppositories if you are pregnant or breastfeeding unless prescribed. Inmeth 50 mg Suppositories causes dizziness, so drive only if you are alert. Inmeth 50 mg Suppositories is not recommended for children as safety has not been established. Avoid consuming alcohol along with Inmeth 50 mg Suppositories as it could lead to increased dizziness and might increase the risk of stomach bleeding. Stop taking Inmeth 50 mg Suppositories and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach like blood in stools.

Drug-Drug Interactions

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IndometacinCidofovir
Critical
IndometacinKetorolac
Critical

Drug-Drug Interactions

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IndometacinCidofovir
Critical
How does the drug interact with Inmeth 50 mg Suppositories:
Co-administration of Indomethacin with Cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Inmeth 50 mg Suppositories with Cidofovir is not recommended as it can lead to an interaction, it can be used if prescribed by a doctor. However, if you experience nausea, vomiting, decreased hunger, increased or decreased urination, weight gain or loss that occurs suddenly, fluid retention, swelling, shortness of breath, cramping in the muscles, weakness, confusion, and irregular heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
IndometacinKetorolac
Critical
How does the drug interact with Inmeth 50 mg Suppositories:
Co-administration of Ketorolac together with Indomethacin may increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, and ulcers.

How to manage the interaction:
Taking Inmeth 50 mg Suppositories with Ketorolac is not recommended, as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
IndometacinLithium
Severe
How does the drug interact with Inmeth 50 mg Suppositories:
Taking lithium with indomethacin may significantly increase the blood levels of lithium.

How to manage the interaction:
Taking Inmeth 50 mg Suppositories with Lithium together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience drowsiness, dizziness, confusion, diarrhoea, vomiting, muscle weakness, muscle incoordination, shaking of hands and legs, blurred vision, ringing in the ear, excessive thirst, and increased urination consult a doctor. Do not stop using any medications without a doctor's advice.
IndometacinDiclofenac
Severe
How does the drug interact with Inmeth 50 mg Suppositories:
The combined use of diclofenac and Indomethacin can increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Co-administration of Diclofenac and Indomethacin can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
IndometacinFondaparinux
Severe
How does the drug interact with Inmeth 50 mg Suppositories:
Taking indomethacin with fondaparinux can increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between fondaparinux and Inmeth 50 mg Suppositories, it can be taken if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness contact a doctor immediately. Do not stop using any medications without talking to a doctor.
IndometacinEdoxaban
Severe
How does the drug interact with Inmeth 50 mg Suppositories:
Using Inmeth 50 mg Suppositories with Edoxaban can increase the risk of bleeding.

How to manage the interaction:
Taking Inmeth 50 mg Suppositories with Edoxaban together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
IndometacinMeloxicam
Severe
How does the drug interact with Inmeth 50 mg Suppositories:
The combined use of Inmeth 50 mg Suppositories and meloxicam can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
Taking Inmeth 50 mg Suppositories with Meloxicam together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
IndometacinRivaroxaban
Severe
How does the drug interact with Inmeth 50 mg Suppositories:
Coadministration of Indomethacin with Rivaroxaban can increase the risk of bleeding problems.

How to manage the interaction:
Taking Inmeth 50 mg Suppositories with Rivaroxaban together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
IndometacinApixaban
Severe
How does the drug interact with Inmeth 50 mg Suppositories:
Coadministration of Indomethacin and Apixaban may raise the risk of bleeding.

How to manage the interaction:
Taking Indomethacin and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
IndometacinAdefovir dipivoxil
Severe
How does the drug interact with Inmeth 50 mg Suppositories:
Using Indomethacin with Adefovir dipivoxil can increase the risk of kidney damage.

How to manage the interaction:
Co-administration of Inmeth 50 mg Suppositories with Adefovir dipivoxil can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you have nausea, vomiting, decreased hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, breathing difficulty, bone pain, muscle cramps, weakness, dizziness, confusion, and irregular heart rhythm, consult the doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listen to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANALGESICS
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Inmeth 50 mg Suppositories. Alcohol intake, along with Inmeth 50 mg Suppositories, may cause increased dizziness. It may also elevate the risk of stomach bleeding.

bannner image

Pregnancy

Unsafe

It is not recommended to use Inmeth 50 mg Suppositories while you are pregnant. Please consult your doctor if you are pregnant or if you are having any concerns regarding this.

bannner image

Breast Feeding

Unsafe

It is not recommended to use Inmeth 50 mg Suppositories while you are breastfeeding. Please consult your doctor if you are breastfeeding or if you are having any concerns regarding this.

bannner image

Driving

Caution

Inmeth 50 mg Suppositories may cause dizziness. Do not drive or operate heavy machinery if you feel dizzy.

bannner image

Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have liver impairment/liver disease.

bannner image

Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have kidney impairment or any concerns regarding this.

bannner image

Children

Unsafe

Inmeth 50 mg Suppositories is not recommended for children as efficacy and safety have not been established.

FAQs

Inmeth 50 mg Suppositories belongs to the group of pain killers known as NSAID's (Non-Steroidal Anti-Inflammatory Drugs) used to relieve symptoms caused by osteoarthritis, ankylosing spondylitis, and rheumatoid arthritis such as stiffness, swelling and joint pain. Inmeth 50 mg Suppositories is also used to treat acute gouty arthritis and bursitis and/or tendinitis (painful shoulder).

Inmeth 50 mg Suppositories works by blocking the effect of chemical messengers (prostaglandin), thereby helps in reducing joint pain, stiffness, swelling and inflammation.

Diarrhoea might be a side-effect of Inmeth 50 mg Suppositories. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you have severe diarrhoea consult your doctor. Do not take anti-diarrheal medicine on your own.

Do not take Inmeth 50 mg Suppositories for longer durations or high doses as it may increase the risk of stomach bleeding. Do not exceed the dose and duration prescribed by your doctor.

Inmeth 50 mg Suppositories may increase the risk of heart attack or stroke. Do not use Inmeth 50 mg Suppositories immediately before or after heart surgery. Consult your doctor before using Inmeth 50 mg Suppositories if you have/ had heart problems.

Inmeth 50 mg Suppositories may affect laboratory test results. Inform the person doing the tests that you are using Inmeth 50 mg Suppositories.

Inmeth 50 mg Suppositories may affect fertility. However, the effect is reversible on stopping Inmeth 50 mg Suppositories. Consult your doctor before using Inmeth 50 mg Suppositories if you are planning to become pregnant.

Country of origin

INDIA

Manufacturer/Marketer address

2Nd Floor, 8-3-166/7/1 Erragadda, Hyderabad-500018
Other Info - INM0026

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Veda MaddalaDoctor badge

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Jul 18, 2025 | 7:00 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.nps.org.au/assets/medicines/acf8856d-f8c1-49fc-956c-a53300ff7736.pdf
  2. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a8ed14ef-cd4b-3be7-0b5f-b677c72d2e88
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/017814s041s042lbl.pdf

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