Regular blood tests are recommended while taking Intalith CR-450 Tablet 10's to check lithium levels in blood. If you are pregnant or breastfeeding, please inform your doctor before taking Intalith CR-450 Tablet 10's. If you have hypothyroidism (underactive thyroid gland), please inform your doctor before taking Intalith CR-450 Tablet 10's as it may cause low thyroid levels. If you notice decreased amount of urine, dark, reddish urine, muscle pain or weakness, inform your doctor immediately as it may be due to a serious condition called rhabdomyolysis (muscle tissue breakdown) which may lead to kidney problems.

Drug-Drug Interaction: Intalith CR-450 Tablet 10's may have interaction with high blood pressure-lowering medicines (ramipril, lisinopril, methyldopa, amlodipine, diltiazem), pain killers (ibuprofen, diclofenac, celecoxib, indomethacin), asthma drugs (theophylline), antipsychotics (olanzapine, haloperidol, clozapine, sertindole), fits related drugs (phenytoin, clonazepam, carbamazepine), heart-related medicines (quinidine, amiodarone, propafenone, ranolazine, procainamide, disopyramide, ajmaline, cibenzoline, hydroquinidine, azimilide, ibutilide, sotalol, dofetilide), antidepressants (paroxetine, amitriptyline, fluoxetine), antibiotics (trimethoprim, spectinomycin, co-trimoxazole, metronidazole, tetracyclines).

Drug-Food Interaction: Intalith CR-450 Tablet 10's may interact with caffeine. Therefore, reduce the intake of caffeine including coffee, tea or herbal medicines as it may decrease the effect of Intalith CR-450 Tablet 10's. Also, avoid alcohol intake as it may increase side effects such as drowsiness, dizziness or difficulty in concentrating. Intake of sodium may also alter lithium levels. Hence, maintain a constant dietary intake of salt.

Drug-Disease Interaction: If you have fits, kidney or heart problems, thyroid, persistent headache, vision problems, Brugada syndrome (a hereditary syndrome affecting the heart), hypothyroidism (low thyroid levels) and low sodium levels, inform your doctor before taking Intalith CR-450 Tablet 10's.

• Avoid low-sodium diet as it may increase lithium levels in blood and cause adverse effects.
• Limit the intake of caffeine as it may reduce the effectiveness of Intalith CR-450 Tablet 10's.
• Do regular exercise and maintain a stable weight as Intalith CR-450 Tablet 10's may cause weight gain.
• Drink plenty of water to avoid dehydration and try to drink same amount of water everyday as any major changes in quantity may affect lithium levels.
• Avoid consumption of alcohol as it may increase drowsiness.

• Regular blood tests are advised every week while taking Intalith CR-450 Tablet 10's to monitor the levels of lithium in blood. When lithium levels are constant, blood tests may be done for every 3 months.
• Drink constant amount of water daily and maintain a constant sodium intake as any major changes in these two may alter the levels of lithium in blood.