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compositionComposition:PACLITAXEL-100MG
prescription
Prescription Medicine
info
Intaxel 100 mg Injection 17 ml

INTAXEL 100MG INJECTION is used to treat various types of cancers, including ovarian and breast cancer (in advanced/spreading state or after surgery) and advanced-stage non-small cell lung cancer. It contains ‘Paclitaxel’, which stops cell division and prevents certain cancer cell growth. Sometimes, INTAXEL 100MG INJECTION may cause common side effects, such as nausea, vomiting, mild diarrhoea, and joint or muscle pain. It is not recommended for children below 18 years.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

PACLITAXEL-100MG

Manufacturer/Marketer :

Fresenius Kabi India Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About INTAXEL 100MG INJECTION

INTAXEL 100MG INJECTION belongs to the group of anti-cancer medicines called anti-microtubule agents used to treat various types of cancers, including ovarian and breast cancer (in advanced/spreading state or after surgery) and advanced-stage non-small cell lung cancer.

INTAXEL 100MG INJECTION contains ‘Paclitaxel’, which works by stopping cell division and preventing the growth of certain cancer cells.

In some cases, INTAXEL 100MG INJECTION may cause common side effects, such as nausea, vomiting, mild diarrhoea, and joint or muscle pain. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.

Consult your doctor if you are pregnant, breastfeeding, think you may be pregnant or are planning pregnancy. INTAXEL 100MG INJECTION is not recommended for children below 18 years. Inform your doctor about your health condition and medications to rule out any side effects.

Uses of INTAXEL 100MG INJECTION

INTAXEL 100MG INJECTION is used in the treatment of ovarian cancer, breast cancer, and non-small cell lung cancer. The detailed uses of INTAXEL 100MG INJECTION are as follows:

  • Treating Ovarian Cancer: INTAXEL 100MG INJECTION helps to treat ovarian cancer by inhibiting cancer cell growth and proliferation.
  • Managing Breast Cancer: INTAXEL 100MG INJECTION is used to manage breast cancer, particularly in patients with metastatic disease, slowing disease progression and improving symptoms.
  • Treating Non-Small Cell Lung Cancer (NSCLC): INTAXEL 100MG INJECTION treats NSCLC by interfering with cell division, inhibiting tumour growth, and slowing disease progression.
  • Reducing Tumour Growth in AIDS-Related Kaposi Sarcoma: INTAXEL 100MG INJECTION also helps to manage Kaposi sarcoma in patients with AIDS by reducing tumour growth and alleviating symptoms.

Key Benefits

INTAXEL 100MG INJECTION belongs to the group of anti-cancer medicines called anti-microtubule agents used to treat various types of cancers, including ovarian and breast cancer (in advanced/spreading state or after surgery) and advanced-stage non-small cell lung cancer. It may also be used when other treatments have failed or in combination with other treatments. INTAXEL 100MG INJECTION may also be indicated in patients with Kaposi’s sarcoma (cancer that develops from the cells that line lymph or blood vessels) associated with AIDS (Acquired Immuno-Deficiency Syndrome), where other treatments have not been effective. INTAXEL 100MG INJECTION contains ‘Paclitaxel’, which works by preventing the growth of certain cancer cells. 

Side effects of Intaxel 100 Mg Injection 16.67 Ml
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
  • Eat protein-rich foods like fish, poultry, eggs, and legumes.
  • Include foods with minerals and vitamins essential for hair health.
  • Join a support group to connect with others experiencing hair loss.
  • Openly discuss your feelings about hair loss.
  • Consider covering up with wigs, hats, or scarves.
  • Be patient and avoid seeking miracle cures.
  • If you experience symptoms such as mouth ulcers, redness, difficulty in swallowing or talking, abdominal pain, and painful bowel movements as a drug side effect, consult your doctor as they may adjust the dose if necessary or prescribe alternative medication.
  • Practice good hygiene, such as washing your hands regularly, to prevent infection.
  • Drink plenty of water to keep your mucous membranes hydrated and promote healing.
  • Avoid spicy or acidic foods, which can irritate the mucous membranes and exacerbate inflammation.
  • Increase your intake of omega-3 fatty acids, found in fatty fish, nuts, and seeds, to reduce inflammation.
  • Follow a soft food diet to reduce discomfort and promote healing.
  • Eat well-cooked food to minimize infection risk.
  • Practice good hand hygiene to prevent infections.
  • Avoid crowds and people with illnesses to reduce exposure.
  • Wear a mask when necessary to lower infection risk.
  • Rest adequately to support your body's healing process.
  • Stay hydrated by drinking plenty of water.
  • Regularly monitor blood cell counts for changes.
  • Seek immediate medical help if symptoms like fever, chills, or fatigue occur.
  • Consult your doctor right away if concerning symptoms arise.
  • Follow your doctor's guidance on managing myelosuppression and infection prevention.
  • Your doctor may recommend regular liver function tests (LFT) to monitor liver enzyme levels.
  • To support your liver, eat a healthy diet with lots of fruits, vegetables, lean proteins, and healthy fats.
  • Avoid eating processed meats, sugary foods, and unhealthy fats.
  • Limit your alcohol consumption, since too much can worsen liver function and contribute to high levels of Alkaline Phosphatase (ALP).
  • Stay active with regular exercise, drink plenty of water, and try to avoid harmful chemicals that can damage your liver.
  • Quit smoking to lower the risk of elevated ALP levels.
  • Try taking pain relievers like paracetamol, ibuprofen or naproxen to releve discomfort and pain.
  • Avoid strenuous activities that worsen muscle and joint pain.
  • Do gentle stretching exercises to enhance muscle flexibility and reduce joint pain.
  • Apply cold or warm compresses to your joints and muscles for pain relief.
  • Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • If your joint/muscle pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • INTAXEL 100MG INJECTION will be administered by the doctor or healthcare professional in a medical setting.
  • Do not self-administer.

How INTAXEL 100MG INJECTION Works

INTAXEL 100MG INJECTION contains Paclitaxel, which works by stopping cell division and preventing the growth of certain cancer cells.
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Alcohol

Consult your doctor

It is not known if alcohol interacts with this medicine. Please consult your doctor.

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Pregnancy

Unsafe

INTAXEL 100MG INJECTION must not be given during pregnancy unless clearly necessary, as it may cause birth defects. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving INTAXEL 100MG INJECTION.

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Breast Feeding

Unsafe

Avoid breastfeeding whilst on treatment with INTAXEL 100MG INJECTION. Do not restart breastfeeding until your doctor tells you it is safe to do so.

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Driving

Caution

INTAXEL 100MG INJECTION may cause dizziness, tiredness, or nausea. Drive or operate heavy machinery only if you are alert.

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Liver

Caution

Do not use INTAXEL 100MG INJECTION if you have severe liver problems. If you have a history of liver disease, inform your doctor before receiving INTAXEL 100MG INJECTION.

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Kidney

Consult your doctor

If you have a history of kidney diseases, inform your doctor before receiving INTAXEL 100MG INJECTION. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

INTAXEL 100MG INJECTION is not recommended for children below 18 years due to a lack of data on the safety and effectiveness.

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Heart

Caution

INTAXEL 100MG INJECTION should be avoided in heart patients unless strictly advised by a specialist. It may cause serious cardiac side effects like low blood pressure or heart rhythm issues.

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Geriatrics

Caution

Geriatric patients may receive INTAXEL 100MG INJECTION, but only with strict medical supervision. Age-related risks like heart issues, neuropathy, and reduced liver function require careful monitoring during therapy.

What if I have taken an overdose of INTAXEL 100MG INJECTION

An overdose of INTAXEL 100MG INJECTION may cause severe bone marrow suppression, mucositis (inflammation of the mucosa), and peripheral neurotoxicity. There is no known antidote for INTAXEL 100MG INJECTION overdose; in case of an overdose, the patient should be closely monitored, and the treatment should be supportive.

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs and spices in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.

Have a query?

How Soon It Starts Working

The time required for INTAXEL 100MG INJECTION to start to work: The time required for INTAXEL 100MG INJECTION to show its action is unknown. The time for which the effects of INTAXEL 100MG INJECTION last: The effect of INTAXEL 100MG INJECTION lasts for 27 hours.

What if you forget to take INTAXEL 100MG INJECTION

As this medication will be administered in a hospital by your healthcare professional, the chances of missing a dose are less. However, if you have any concerns, contact your doctor.

Storage

• Store in a cool and dry place away from sunlight.• Keep INTAXEL 100MG INJECTION out of sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
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Keep Refrigerated. Do not freeze.

Drug Warnings

Do not take INTAXEL 100MG INJECTION if you are allergic to any of its components, if your white blood cell or platelet count is very low (< 1,500 cells/mm3), if you have a serious uncontrolled infection, or if you have severe liver problems. Inform your doctor if you have heart disease, abnormal blood cell counts, irregular heartbeat, tingling, numbness, or burning sensation in fingers or toes, visual problems, if you are on radiation therapy, or if you have Kaposi’s sarcoma and have a sore or inflamed mouth. Also, inform your doctor if you are pregnant, breastfeeding, think you are pregnant or planning pregnancy.

Drug-Drug Interactions

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Drug-Drug Interactions: Inform your doctor if you are taking antibiotics (rifampicin, erythromycin), anti-fungal (ketoconazole), anti-depressant (fluoxetine), anti-epileptic (carbamazepine, phenytoin), lipid regulating agent (gemfibrozil), antacid (cimetidine), medicines used to treat HIV/AIDS (ritonavir, saquinavir, indinavir, nelfinavir, efavirenz, nevirapine), anti-platelet (clopidogrel).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Inform your doctor if you have a very low white blood cell or platelet count, a serious uncontrolled infection, or severe liver problems.

PaclitaxelEtanercept
Severe
PaclitaxelClozapine
Severe

Drug-Drug Interactions

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PaclitaxelEtanercept
Severe
How does the drug interact with Intaxel 100 Mg Injection 16.67 Ml:
When Etanercept is used with Intaxel 100 Mg Injection 16.67 Ml, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between Etanercept and Intaxel 100 Mg Injection 16.67 Ml, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
PaclitaxelClozapine
Severe
How does the drug interact with Intaxel 100 Mg Injection 16.67 Ml:
Combining Intaxel 100 Mg Injection 16.67 Ml with Clozapine can increase the risk of infection.

How to manage the interaction:
Taking Intaxel 100 Mg Injection 16.67 Ml with Clozapine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
PaclitaxelTofacitinib
Severe
How does the drug interact with Intaxel 100 Mg Injection 16.67 Ml:
Taking Tofacitinib with Intaxel 100 Mg Injection 16.67 Ml may increase the risk of infection.

How to manage the interaction:
Although taking Intaxel 100 Mg Injection 16.67 Ml and Tofacitinib together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
PaclitaxelCladribine
Severe
How does the drug interact with Intaxel 100 Mg Injection 16.67 Ml:
Combining Cladribine with Intaxel 100 Mg Injection 16.67 Ml can increase the risk of developing serious infections.

How to manage the interaction:
Taking Intaxel 100 Mg Injection 16.67 Ml with Cladribine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
PaclitaxelInfliximab
Severe
How does the drug interact with Intaxel 100 Mg Injection 16.67 Ml:
Combining Infliximab with Intaxel 100 Mg Injection 16.67 Ml can enhance the breakdown of Intaxel 100 Mg Injection 16.67 Ml in the body. This can reduce the treatment outcomes and can increase the risk or severity of developing serious infections.

How to manage the interaction:
Taking Intaxel 100 Mg Injection 16.67 Ml with Infliximab together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PaclitaxelRitonavir
Severe
How does the drug interact with Intaxel 100 Mg Injection 16.67 Ml:
Taking Ritonavir and Intaxel 100 Mg Injection 16.67 Ml may significantly increase the blood levels of Intaxel 100 Mg Injection 16.67 Ml.

How to manage the interaction:
Taking Ritonavir with Intaxel 100 Mg Injection 16.67 Ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. In case of any unusual symptoms, consult a doctor. Do not stop using any medications without talking to a doctor.
PaclitaxelThalidomide
Severe
How does the drug interact with Intaxel 100 Mg Injection 16.67 Ml:
Taking thalidomide together with Intaxel 100 Mg Injection 16.67 Ml may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Intaxel 100 Mg Injection 16.67 Ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
PaclitaxelBaricitinib
Severe
How does the drug interact with Intaxel 100 Mg Injection 16.67 Ml:
Coadministration of baricitinib and Intaxel 100 Mg Injection 16.67 Ml can raise the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Intaxel 100 Mg Injection 16.67 Ml if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[CHEMOTHERAPY]

FAQs

INTAXEL 100MG INJECTION is used to treat Ovarian cancer, breast cancer, non-small cell lung cancer.
INTAXEL 100MG INJECTION works by stopping cell division and preventing the growth of certain cancer cells.
INTAXEL 100MG INJECTION might cause sterility which could be permanent. Please talk to your doctor if you have any concerns.
The most common side effect of INTAXEL 100MG INJECTION is hair loss. The hair may grow back after the treatment with INTAXEL 100MG INJECTION is finished. However, consult your doctor if you have any concerns.
Yes, INTAXEL 100MG INJECTION is cytotoxic. It works by interfering with the growth of cancer cells, preventing them from dividing and causing them to die. However, its cytotoxic nature also means it can affect normal, healthy cells, potentially leading to side effects.
Yes, INTAXEL 100MG INJECTION is considered a vesicant. A vesicant is a chemical substance that, if it leaks out of the vein (extravasation), can cause blistering of the skin and surrounding tissues. If INTAXEL 100MG INJECTION accidentally leaks during intravenous (IV) infusion, it may lead to inflammation, blistering, or even tissue necrosis. Your healthcare provider will take precautions to ensure the drug is infused properly and monitor the infusion site for any signs of leakage. If extravasation occurs, the infusion should be stopped immediately, and steps should be taken to minimize the damage.
INTAXEL 100MG INJECTION is an effective cancer treatment with a low risk of cardiac side effects. Your healthcare team will closely monitor your heart function to ensure your safety. They'll watch for any changes in heart rhythms or blood pressure, and work with you to manage any potential issues. With careful monitoring, you can receive this life-saving treatment with confidence.
INTAXEL 100MG INJECTION is a natural product derived from the bark of the Pacific yew tree (Taxus baccata). It is a chemotherapy medication used to treat various cancers, including breast, ovarian, and lung cancer.
The common side effects of INTAXEL 100MG INJECTION include nausea, vomiting, mild diarrhoea, and joint or muscle pain. Not everyone will experience all of these side effects, and they typically resolve once the treatment is stopped. However, if the side effects persist or worsen, please consult your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.3891 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  2. Paclitaxel Paclitaxel. 2005. [Accessed on 24 Jan. 2019] Check here
  3. Paclitaxel Paclitaxel. 2005. [Accessed on 26 Mar. 2019] Check here
  4. Drugs and Lactation Database (LactMed) [Internet]. 2006. [Accessed on 18 Feb. 2020] Check here
  5. Abraxane 5 mg/ml powder for dispersion for infusion - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2024 [Accessed on 31 December 2024] Check here
  6. Abraxane 5 mg/ml powder for dispersion for infusion - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2024 [Accessed on 31 December 2024] Check here
  7. Maela C. Farrar; Tibb F. Jacobs. Paclitaxel. NIH National Library of Medicine. National Center for Biotechnology Information. StatPearls [Internet]. [Revised in May 2022] [Accessed on 7th October 2021]Check here

Country of origin

India

Manufacturer/Marketer address

Plot No 11 Echleon, Institutional Area, Sector 32, Gurugram, Haryana 122018
Other Info - INT0005

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