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compositionComposition:IBUPROFEN-400MG
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Inzan 400 mg Infusion is used to treat pain and inflammation caused by musculoskeletal conditions. This medicine is also used in post-operative pain management plans. It contains Ibuprofen, which works by blocking the effect of a chemical known as prostaglandin, which mediates the pain pathway in our body. Common side effects of this medication include stomach pain, headache, diarrhoea, nausea, vomiting, and injection site reactions.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

IBUPROFEN-400MG

Manufacturer/Marketer :

Hetero Healthcare Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Inzan 400 mg Infusion

Inzan 400 mg Infusion is an injectable medication used to manage mild to moderate pain, moderate to severe pain, and to lower high body temperatures. It is typically used in hospital or clinical settings when oral medications are not possible or practical. This treatment helps bring rapid relief to patients recovering from surgery or those experiencing acute pain episodes.

This medicine is given as an injection or a slow infusion into a vein by a healthcare professional. The frequency of your treatment will depend entirely on your specific clinical condition and how well you respond to it. To help support your recovery, your care team may also recommend rest and lifestyle adjustments, such as drinking plenty of fluids and avoiding strenuous physical activity while you heal.

While this medication is highly effective, some people may experience mild side effects like nausea, headache, or slight irritation at the injection site. However, you must inform your doctor or nurse immediately if you experience serious side effects, such as dark, tarry stools, sudden shortness of breath, or severe stomach pain.

Do not take this if you have a history of severe allergic reactions to aspirin or other similar pain relievers. Before receiving this medicine, tell your doctor if you have a history of asthma, heart problems, high blood pressure, stomach ulcers, or kidney disease, as special precautions may be needed.

This medication can interact with other drugs, including blood thinners, water pills, and certain blood pressure medicines, which may increase your risk of bleeding or kidney strain. Drinking alcohol or smoking during your treatment course can also raise your risk of stomach irritation. If you are pregnant (especially in the last three months), breastfeeding, or an older adult, talk to your doctor or pharmacist before receiving this medicine.

Uses of Inzan 400 mg Infusion

Inzan 400 mg Infusion is used in the treatment of Pain and Inflammation. The detailed uses of Inzan 400 mg Infusion are as follows:

  • Moderate to severe pain: Inzan 400 mg Infusion helps reduce severe discomfort, particularly after surgical procedures, often when combined with other pain-relief medications.
  • Fever reduction: It works efficiently to lower high body temperature in adults who cannot take medications by mouth.
  • Inflammation control: It targets swelling and tenderness in the body associated with acute injuries or inflammatory flare-ups.

Key Benefits

  • Provides rapid pain relief because it is given directly into a vein, allowing it to enter the bloodstream quickly without passing through the digestive system.
  • Helps reduce fever quickly, making it useful when fast temperature control is needed.
  • An effective option for patients who cannot take medicines by mouth, such as after surgery, during severe nausea or vomiting, or when swallowing is difficult.
  • Offers reliable pain relief in hospital settings, especially after surgery or during acute illness.
  • May reduce the need for opioid pain medicines, helping lower the risk of opioid-related side effects such as excessive drowsiness, confusion, constipation, and nausea.
  • Supports faster recovery and improved comfort by effectively managing pain and fever when oral medicines are not suitable.
Side effects of Inzan 400 mg Infusion
  • Take cold water baths avoiding soap.
  • Avoid scratching and scrubbing to prevent infections while itching.
  • Use nets to prevent insects and mosquitoes.
  • Stop using lotions and creams that cause irritation.
  • Avoid alcohol and caffeine intake.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Inzan 400 mg Infusion will be administered by a healthcare professional.
  • Do not self-administer it.

How Inzan 400 mg Infusion Works

Inzan 400 mg Infusion belongs to a class of medications called non-steroidal anti-inflammatory drugs (NSAIDs). It works by blocking the activity of natural enzymes in your body known as cyclooxygenase (COX) enzymes. These enzymes are responsible for producing chemicals called prostaglandins, which your body releases in response to injury or illness. Prostaglandins cause pain, swelling, and fever. By stopping these enzymes from making these chemicals, Inzan 400 mg Infusion effectively reduces pain signals, minimizes swelling, and lowers body temperature.
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Alcohol

Unsafe

Avoid consuming alcohol along with Inzan 400 mg Infusion as it may worsen gastrointestinal adverse effects.

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Pregnancy

Caution

If you are pregnant or plan to have a baby, inform your doctor before using this medication. Inzan 400 mg Infusion should also be avoided if you intend to become pregnant, as the medication may make conception more difficult.

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Breast Feeding

Caution

Inzan 400 mg Infusion is only present in trace amounts in breast milk. If you are breastfeeding, you should not use this medicine for long periods or in heavy doses.

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Driving

Not applicable

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Liver

Caution

Inform your doctor if you have/had liver disease before receiving Inzan 400 mg Infusion. Dose adjustment may be needed based on your health condition.

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Kidney

Caution

Inzan 400 mg Infusion should be used cautiously for mild to moderate kidney disease. Dose adjustment may be needed based on the health condition. It is not recommended in case of severe kidney disease. Inform your doctor if you have/had kidney diseases before receiving Inzan 400 mg Infusion.

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Children

Unsafe

Inzan 400 mg Infusion is not recommended for use in children below 18 years of age as the safety and efficacy are not established.

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Heart

Caution

Inzan 400 mg Infusion may increase the risk of heart problems. Therefore, please consult your doctor if you have any heart-related problems before using Inzan 400 mg Infusion.

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Geriatrics

Safe if prescribed

Inzan 400 mg Infusion is generally safe for geriatric individuals. Please consult your doctor if you have any concerns.

What if I have taken an overdose of Inzan 400 mg Infusion

Since this medicine is prepared and measured carefully by healthcare professionals, an overdose is extremely rare. However, if you experience sudden symptoms like severe stomach pain, extreme drowsiness, shallow breathing, or confusion, notify your healthcare provider immediately.

Diet & Lifestyle Advise

  • Drink plenty of water before and after your infusion, as staying well-hydrated helps protect your kidneys while receiving this medicine.
  • If you experience mild stomach upset after your treatment, stick to simple, bland meals and avoid highly spiced, greasy, or acidic foods.
  • Ensure you get adequate rest to allow your body to heal and recover from the underlying illness or surgery.
  • Avoid drinking alcohol during your treatment period, as it can significantly increase your risk of stomach irritation and bleeding.
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How Soon It Starts Working

The time required for Inzan 400 mg Infusion to start to work: Inzan 400 mg Infusion ideally shows its action within an hour after administration. The time for which the effects of Inzan 400 mg Infusion last: The effect of Inzan 400 mg Infusion lasts for 4 to 6 hours.

What if you forget to take Inzan 400 mg Infusion

Because this medication is scheduled and given by medical professionals in a clinic or hospital, it is highly unlikely that you will miss a dose. If you believe a scheduled dose has been missed or delayed, notify your nurse or doctor right away.

Storage

•Store Inzan 400 mg Infusion vials or infusion bags at room temperature, ideally between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Always inspect the liquid inside the vial or infusion bag before it is given; it should be clear and colorless. Do not use if you see particles or discoloration.
  • Ensure your healthcare provider uses a new, sterile needle and syringe for every injection, and disposes of them in a puncture-proof sharps container.
  • Monitor your injection site closely during the infusion and immediately report any feelings of burning, pain, swelling, or redness to your nurse.
  • Tell your surgical or dental team that you have received Inzan 400 mg Infusion, as this medicine can temporarily affect how your blood clots.
  • Do not receive this medicine if you are in your third trimester of pregnancy, as it can cause serious developmental issues for the unborn baby.

Drug-Drug Interactions

verifiedApollotooltip
  • Blood thinners (like warfarin): May increase the risk of severe stomach bleeding.
  • Water pills (diuretics) and blood pressure medicines: Inzan 400 mg Infusion may reduce their effectiveness and increase the strain on your kidneys.
  • Other NSAIDs or aspirin: Combining these can significantly raise the risk of stomach ulcers and internal bleeding.
  • Lithium: May increase lithium levels in your blood, potentially leading to toxic side effects.

Drug-Drug Interactions

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How does the drug interact with Inzan 400 mg Infusion:
Taking Ketorolac and Inzan 400 mg Infusion can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding and ulceration.

How to manage the interaction:
Taking Ketorolac and Inzan 400 mg Infusion together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, red or black, dark stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Inzan 400 mg Infusion:
Combining Meloxicam and Inzan 400 mg Infusion can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
Taking Meloxicam and Inzan 400 mg Infusion together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, red or black, dark stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Inzan 400 mg Infusion:
Coadministration of Tenofovir disoproxil and Inzan 400 mg Infusion can increase the risk of developing kidney problems.

How to manage the interaction:
Co-administration of Tenofovir disoproxil and Inzan 400 mg Infusion can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, irregular urination, sudden weight gain or weight loss, shortness of breath, muscle cramps, weakness, and irregular heart rhythm, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Inzan 400 mg Infusion:
The combined use of Cabozantinib and Inzan 400 mg Infusion can increase the risk of bleeding.

How to manage the interaction:
using Cabozantinib and Inzan 400 mg Infusion can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black tarry stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Inzan 400 mg Infusion:
The combined use of Teriflunomide and Inzan 400 mg Infusion can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Inzan 400 mg Infusion can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, light- colored stools, and/or yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Inzan 400 mg Infusion:
Taking risedronic acid with Inzan 400 mg Infusion can increase the risk of developing kidney problems, gastrointestinal bleeding, and ulcers.

How to manage the interaction:
Co-administration of Risedronic acid and Inzan 400 mg Infusion can lead to an interaction but it can be taken if your doctor has advised it. However, consult your doctor if you experience abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools. Do not discotinue any medications without consulting a doctor.
How does the drug interact with Inzan 400 mg Infusion:
Co-administration of Rivaroxaban and Inzan 400 mg Infusion can increase the risk of bleeding problems.

How to manage the interaction:
Co-administration of Rivaroxaban and Inzan 400 mg Infusion can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Inzan 400 mg Infusion:
Taking cidofovir and Inzan 400 mg Infusion can increase the risk of Kidney problems.

How to manage the interaction:
Taking Cidofovir and Inzan 400 mg Infusion can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss , swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Inzan 400 mg Infusion:
Use of Etodolac and Inzan 400 mg Infusion can increase the risk of side effects in the gastrointestinal tract (inflammation, bleeding, ulceration, and rarely perforation).

How to manage the interaction:
Taking Etodolac and Inzan 400 mg Infusion together can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenVorapaxar
Severe
How does the drug interact with Inzan 400 mg Infusion:
The combined use of Vorapaxar and Inzan 400 mg Infusion can increase the risk of bleeding, including severe and sometimes haemorrhage.

How to manage the interaction:
Co-administration of Vorapaxar and Inzan 400 mg Infusion can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache; and weakness. consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Drinking alcohol while undergoing treatment can significantly increase the risk of stomach irritation and gastrointestinal bleeding.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANALGESICS]

FAQs

Inzan 400 mg Infusion is used to treat Pain and Inflammation.
Inzan 400 mg Infusion contains Ibuprofen, which works by blocking the effect of a chemical known as prostaglandin, which is responsible for inducing pain and inflammation in the body.
No. Inzan 400 mg Infusion is contraindicated in patients with stomach ulcers. Before taking Inzan 400 mg Infusion, tell your doctor if you have ever had a stomach or duodenal ulcer, bowel ulcer, ulcerative colitis, or Crohn's disease, liver/kidney disease or a respiratory condition.
No, Inzan 400 mg Infusion is a parenteral medicine that must be prepared and given by a healthcare professional in a clinic or hospital setting. Talk to your doctor if you have questions about your treatment plan.
You should avoid using Inzan 400 mg Infusion during pregnancy, especially during the last three months, as it can cause complications for your baby. Talk to your doctor to discuss safer pain relief alternatives.
Do not take this if you have active stomach ulcers or a history of gastrointestinal bleeding, as it can worsen these conditions. Talk to your doctor about your complete medical history before starting treatment.
Mild soreness or redness at the injection site is common and usually resolves quickly. If the pain worsens, or if you notice swelling, warmth, or severe tenderness, tell your healthcare provider immediately.
Since Inzan 400 mg Infusion can sometimes cause dizziness, drowsiness, or lightheadedness, you should avoid driving or operating machinery until you know how the medication affects you. Talk to your doctor for advice.
Yes, taking Inzan 400 mg Infusion with other NSAIDs or aspirin can increase the risk of side effects like stomach bleeding and ulcers. Talk to your doctor or pharmacist before combining any pain medications.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

2Nd Floor, 8-3-166/7/1 Erragadda, Hyderabad-500018
Other Info - INZ0017
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