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  3. Isolazine Tablet 15's

Isolazine Tablet 15's, Pack of 15 TABLETS
Isolazine Tablet 15's, Pack of 15 TABLETS
Isolazine Tablet 15's, Pack of 15 TABLETS
Isolazine Tablet 15's, Pack of 15 TABLETS
Isolazine Tablet 15's, Pack of 15 TABLETS
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Isolazine Tablet is used to treat heart failure. It contains Isosorbide dinitrate and Hydralazine, which relaxes the heart's muscles and widens the heart's veins and arteries for easy flow of blood to every part of the body. Thus, it helps lower raised blood pressure and treat heart failure. It may cause side effects like headache, nausea, dizziness, and lightheadedness (feeling faint). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

HYDRALAZINE-37.5MG + ISOSORBIDE DINITRATE-20MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Isolazine Tablet

Isolazine Tablet belongs to a group of medicines called vasodilators used to treat heart failure. Heart failure occurs when the heart muscle does not pump blood normally, including shortness of breath, swollen legs, fatigue and increased heartbeat. In this condition, the heart becomes too weak and cannot pump enough blood and oxygen to the organs and tissues of the body. 

Isolazine Tablet contains Isosorbide dinitrate and Hydralazine. Isosorbide dinitrate relaxes the heart's muscles and widens the heart's veins and arteries for easy flow of blood to every part of the body. Hydralazine helps lower raised blood pressure by relaxing and widening the heart's muscles. Together, Isolazine Tablet helps treat heart failure.

Take Isolazine Tablet as your doctor has prescribed it. In some cases, Isolazine Tablet can cause side effects like headache, nausea, dizziness, and lightheadedness (feeling faint). Most of these side effects of Isolazine Tablet do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

If you are known to be allergic to Isolazine Tablet or any other medicines, please inform your doctor. Before taking Isolazine Tablet , let your doctor know if you have had a heart attack within the last 30 days, low blood pressure, stroke (inadequate blood supply in the brain that causes damage to the brain), or high pressure within the brain. Please do not stop taking Isolazine Tablet on your own, as it may lead to the recurrence of symptoms or worsen the condition.

Uses of Isolazine Tablet

Treatment of Heart failure.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Isolazine Tablet belongs to a group of vasodilators used to treat heart failure. Isolazine Tablet contains Isosorbide dinitrate and Hydralazine. Isosorbide dinitrate belongs to a group of drugs known as nitrates. Isosorbide dinitrate relaxes the heart's muscles and stretches or enlarges the heart's veins and arteries. Hydralazine belongs to a group of drugs known as vasodilators, which help lower raised blood pressure by relaxing and widening the heart's blood vessels.

How Isolazine Tablet Works

Isolazine Tablet contains Isosorbide dinitrate and Hydralazine. Isosorbide dinitrate relaxes the heart's muscles and widens the heart's veins and arteries for easy flow of blood to every part of the body. Hydralazine helps lower raised blood pressure by relaxing and widening the heart's muscles. Together, Isolazine Tablet helps treat heart failure.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Isolazine Tablet

  • Headache
  • Nausea
  • Dizziness
  • Lightheadedness (feeling faint)

What if I have taken an overdose of Isolazine Tablet

Do not take more than the prescribed dose of Isolazine Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Isolazine Tablet if you have low blood pressure because even a low dose of Isolazine Tablet may produce low blood pressure. If you are pregnant or planning any pregnancy, let your doctor know about this before taking Isolazine Tablet as it crosses the placenta and can affect the unborn baby (fetus). Do not drive by using this Isolazine Tablet because it produces dizziness that may cause an accident. You may experience tingling or numbness, so your doctor may prescribe a vitamin B6 supplement (pyridoxine). Hydralazine passes into breast milk, so its use in lactating mothers should be avoided. 

Drug-Drug Interactions

verifiedApollotooltip
Isosorbide dinitrateAvanafil
Critical
Isosorbide dinitrateRiociguat
Critical

Drug-Drug Interactions

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Isosorbide dinitrateAvanafil
Critical
How does the drug interact with Isolazine Tablet:
Taking Avanafil with Isolazine Tablet can cause low blood pressure.

How to manage the interaction:
Taking Isolazine Tablet with Avanafil is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, priapism in males (persistent and painful erection unrelated to sexual activity). Do not discontinue any medications without consulting a doctor.
Isosorbide dinitrateRiociguat
Critical
How does the drug interact with Isolazine Tablet:
Taking Riociguat with Isolazine Tablet may lead to excessively low blood pressure.

How to manage the interaction:
Taking Isolazine Tablet with Riociguat is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, priapism in males (persistent and painful erection unrelated to sexual activity). Do not discontinue any medications without consulting a doctor.
Isosorbide dinitrateTadalafil
Critical
How does the drug interact with Isolazine Tablet:
Taking Tadalafil with Isolazine Tablet can increase the risk or severity of low blood pressure.

How to manage the interaction:
Taking Isolazine Tablet with Tadalafil is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, or heart palpitations. Do not discontinue any medications without consulting a doctor.
Isosorbide dinitrateSildenafil
Critical
How does the drug interact with Isolazine Tablet:
Coadministration of Isolazine Tablet and Sildenafil can increase the risk of low blood pressure.

How to manage the interaction:
Taking Isolazine Tablet and Sildenafil together is generally avoided as it can lead to an interaction, it can be taken only if advised by your doctor. However, if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, and priapism (prolonged and painful erection unrelated to sexual activity) contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Isosorbide dinitrateRopivacaine
Severe
How does the drug interact with Isolazine Tablet:
Taking Isolazine Tablet with ropivacaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking Isolazine Tablet and ropivacaine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
Isosorbide dinitrateBupivacaine
Severe
How does the drug interact with Isolazine Tablet:
Combining Bupivacaine with Isolazine Tablet can increase the risk of methemoglobinemia(a rare condition that can lead to oxygen deprivation in tissues and vital organs due to reduced oxygen-carrying capacity of the blood).

How to manage the interaction:
Co-administration of Bupivacaine with Isolazine Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like grey discolouration of the skin, abnormal blood colouration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, confusion, consult a doctor right away. Do not stop using any medications without a doctor's advice.
Isosorbide dinitrateErgotamine
Severe
How does the drug interact with Isolazine Tablet:
Taking Isolazine Tablet together with ergotamine can increase the effects of ergotamine.

How to manage the interaction:
Although taking Isolazine Tablet and ergotamine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience an irregular heartbeat, nausea, vomiting, weakness, or coldness, numbness, chest pain or pain in the hands, feet, arms, or legs. Do not discontinue any medications without consulting a doctor.
Isosorbide dinitrateChloroprocaine
Severe
How does the drug interact with Isolazine Tablet:
Taking Isolazine Tablet with chloroprocaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking Isolazine Tablet and chloroprocaine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitations, anxiety, or confusion. Do not stop using any medications without consulting doctor.
Isosorbide dinitrateLidocaine
Severe
How does the drug interact with Isolazine Tablet:
Taking Isolazine Tablet with lidocaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking Isolazine Tablet and lidocaine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
Isosorbide dinitrateCabergoline
Severe
How does the drug interact with Isolazine Tablet:
Taking Isolazine Tablet with cabergoline can increase the effects of Cabergoline.

How to manage the interaction:
Although taking Isolazine Tablet and cabergoline together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. Do not stop using any medications without consulting doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Follow a cholesterol-lowering diet.
  • Consume low salt and a low-fat diet.
  • Exercise regularly. It helps in maintaining proper weight and lowers cholesterol.
  • Limit salt and sugar intake.
  • Avoid smoking and alcohol consumption.
  • Choose healthy fats and cut down on trans fat.
  • Include omega-3 fatty acids, fibre-rich food, fruits, and vegetables.
  • Get active by doing physical activities such as swimming, brisk walking, or jogging. Take the stairs instead of elevators/lifts.

Habit Forming

No

Therapeutic Class

VASODILATORS

Isolazine Tablet Substitute

Substitutes safety advice

  • Nitrohart Tablet 10's

    by AYUR

    ₹7.92per tablet

  • Apresol Plus Tablet 10's

    by AYUR

    ₹9.95per tablet

  • Isozac Tablet 10's

    by Others

    ₹10.80per tablet

  • Hydrozolin Isdn Tablet 10's

    by Others

    ₹12.51per tablet

  • Isorus Tablet 10's

    by Others

    ₹9.86per tablet

Product Substitutes

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Alcohol

Caution

Consuming alcohol with the Isolazine Tablet is not advisable as it may cause unpleasant side effects, or you may become more sensitive to the effects of alcohol.

bannner image

Pregnancy

Caution

Isolazine Tablet is not recommended during pregnancy. Please discuss with the doctor if you have any concerns.

bannner image

Breast Feeding

Caution

Isolazine Tablet is not recommended during nursing. Please discuss with the doctor if you have any concerns.

bannner image

Driving

Caution

Isolazine Tablet may cause dizziness in some people, so it may affect your ability to drive.

bannner image

Liver

Caution

Isolazine Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

bannner image

Kidney

Caution

Isolazine Tablet to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

bannner image

Children

Caution

The safety and effectiveness of Isolazine Tablet in children have not been established.

FAQs

Isolazine Tablet is used to treat heart failure, a condition that occurs when the heart does not pump enough blood for the body's needs.

Isolazine Tablet relaxes the heart's muscles and widens the heart's veins and arteries for easy flow of blood to every part of our body. It helps lower raised blood pressure by relaxing and widening the heart's muscles.

No, keep using the Isolazine Tablet as advised by your doctor, even if you feel well. Stopping the Isolazine Tablet suddenly may lead to serious complications of heart failure.

Yes, the use of Isolazine Tablet can make you feel dizzy. This may often occur when you suddenly rise from a sitting or lying position. To lower the chance of feeling dizzy (faint) or passing out, rise slowly if you have been lying down or sitting.

Keep this medicine tightly closed in the container or the pack it came in. Store it according to the instructions mentioned on the pack or label. Dispose of unused medicine. Make sure pets, children, and other people do not consume it.

Isolazine Tablet may cause headache in some individuals, as it is reported as a common side effect. However, this effect does not require medical attention and gradually resolves over time. If this side effect persists longer, please consult your doctor.

Take Isolazine Tablet with or without food, accompanied by a glass of water. Swallow the tablet whole, without chewing, breaking, or crushing it. Follow your doctor's instructions for dose and duration, and complete the entire prescribed course.

The common side effects of the Isolazine Tablet that may occur in some individuals are headache, nausea, dizziness, and light headedness (faint feeling). Most of these side effects of Isolazine Tablet do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

No, it is advisable not to drink alcohol while taking Isolazine Tablet . Drinking alcohol during treatment may cause increased dizziness and drowsiness or it may cause unpleasant side effects.

Yes, there are some precautions or warnings associated with Isolazine Tablet . Exercise caution while using this medication and it is not advisable for individuals with low blood pressure. Pregnant or breastfeeding women should consult their doctor before use. Additionally, it may cause dizziness, so driving after taking this medication is not recommended.

If you miss a dose of Isolazine Tablet , take it as soon as you remember. However, if it's close to your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Never take a double dose to make up for a missed one.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - ISO0247

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Author Details

Doctor imageDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Doctor imageDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 2:49 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.drugs.com/mtm/isosorbide-dinitrate.html
  2. https://www.rxlist.com/bidil-drug.htm#warnings
  3. https://www.webmd.com/drugs/2/drug-93713/isosorbide-hydralazine-oral/details
  4. https://www.drugs.com/cdi/isosorbide-dinitrate-and-hydralazine.html
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