Isolazine Tablet 15's
MRP ₹216
(Inclusive of all Taxes)
₹32.4 Cashback (15%)
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Genuine Products
Composition :
HYDRALAZINE-37.5MG + ISOSORBIDE DINITRATE-20MG
Manufacturer/Marketer :
Lupin Ltd
Consume Type :
ORAL
Return Policy :
Not Returnable
Expires on or after :
About Isolazine Tablet
Isolazine Tablet belongs to a group of medicines called vasodilators used to treat heart failure. Heart failure occurs when the heart muscle does not pump blood normally, including shortness of breath, swollen legs, fatigue and increased heartbeat.
Isolazine Tablet contains Isosorbide dinitrate and Hydralazine. Isosorbide dinitrate relaxes the heart's muscles and widens the heart's veins and arteries for easy flow of blood to every part of the body. Hydralazine helps lower raised blood pressure by relaxing and widening the heart's muscles.
In some cases, Isolazine Tablet can cause side effects like headache, nausea, dizziness, and lightheadedness. Most of these side effects of Isolazine Tablet do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.
If you are known to be allergic to Isolazine Tablet or any other medicines, please inform your doctor. Before taking Isolazine Tablet , let your doctor know if you have had a heart attack within the last 30 days, low blood pressure, stroke (inadequate blood supply in the brain that causes damage to the brain), or high pressure within the brain.
Uses of Isolazine Tablet
Isolazine Tablet is used for the treatment of heart failure. The detailed uses of Isolazine Tablet are as follows:
- Angina pectoris treatment: Isolazine Tablet helps to relieve angina pectoris symptoms by widening blood vessels and improving blood flow to the heart, reducing chest pain.
- Prevention of angina attacks: Isolazine Tablet can be administered to prevent the occurrence of angina attacks, especially during physical activity or stressful situations.
- Management of heart failure: Isolazine Tablet helps to manage heart failure symptoms by reducing the heart workload and improving blood flow, often used alongside other medications for better heart function.
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Directions for Use
- Isolazine Tablet can be taken with or without food, as advised by your doctor.
- It is usually taken 3 times daily or as prescribed by your doctor.
- Swallow Isolazine Tablet as a whole with a glass of water.
- Do not crush, chew, or break it.
Medicinal Benefits
- Isolazine Tablet belongs to a group of vasodilators used to treat heart failure.
- Isolazine Tablet contains Isosorbide dinitrate and Hydralazine. Isosorbide dinitrate belongs to a group of drugs known as nitrates.
- Isosorbide dinitrate relaxes the heart's muscles and stretches or enlarges the heart's veins and arteries.
- Hydralazine belongs to a group of drugs known as vasodilators, which help lower raised blood pressure by relaxing and widening the heart's blood vessels.
How Isolazine Tablet Works
Isolazine Tablet contains Isosorbide dinitrate and Hydralazine. Isosorbide dinitrate relaxes the heart's muscles and widens the heart's veins and arteries for easy flow of blood to every part of the body. Hydralazine helps lower raised blood pressure by relaxing and widening the heart's muscles. Together, Isolazine Tablet helps treat heart failure.
Storage
• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Isolazine Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
- Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
- Divide your daily food intake into smaller, more frequent meals to reduce nausea.
- Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
- Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
- Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
- Use ginger (tea, ale, or candies) to help relieve nausea.
- Get adequate rest and also avoid strenuous activities that can worsen nausea.
- Talk to your doctor about taking anti-nausea medication if your nausea is severe.
- Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Dealing with Medication-Induced Headache:
- Hydrate your body: Drink enough water to prevent dehydration and headaches.
- Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
- Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
- Take rest: lie down in a quiet, dark environment.
- Cold or warm compresses can help reduce tension.
- Stay Upright: Maintain good posture to keep symptoms from getting worse.
- To treat headaches naturally, try acupuncture or massage therapy.
- Over-the-counter pain relievers include acetaminophen and ibuprofen.
- Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
- Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
- Frequent Headaches: If you get reoccurring headaches, consult your doctor.
- Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
- Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
- Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
- When standing up, do so slowly and carefully to avoid sudden dizziness.
- Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
- Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
- If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
- Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
- Rest well; get enough sleep.
- Eat a balanced diet and drink enough water.
- Manage stress with yoga and meditation.
- Limit alcohol and caffeine.
- Physical activities like walking or jogging might help boost energy and make you feel less tired.
- Change positions or take a break from activity to relieve symptoms.
- Avoid postures that put a lot of pressure on just one area of the body.
- If you have vitamin deficiency, take supplements or change your diet.
- Exercise regularly like cycling, walking or swimming.
- Avoid sitting with your legs crossed.
- Clench and unclench your fists and wiggle your toes.
- Massage the affected area.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
- If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
- Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
- As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
- Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
- Take regular breaks to sit or lie down if you need to stand for long periods.
- When lying down, elevate your head with extra pillows to help improve blood flow.
- Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
- Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
- If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
What if I have taken an overdose of Isolazine Tablet
Do not take more than the prescribed dose of Isolazine Tablet as it may cause serious adverse effects. If you suspect you have taken overdose, please consult a doctor immediately.
Drug Warnings
- Do not take Isolazine Tablet if you are allergic to any of its components.
- Do not take Isolazine Tablet if you have low blood pressure because even a low dose of Isolazine Tablet may cause your blood pressure to drop.
- If you are pregnant or planning any pregnancy, let your doctor know about this before taking Isolazine Tablet as it crosses the placenta and can affect the unborn baby (fetus).
- Do not drive while using this Isolazine Tablet because it can cause dizziness that may lead to an accident.
- You may experience tingling or numbness, so your doctor may prescribe a vitamin B6 supplement (pyridoxine).
- Hydralazine passes into breast milk, so its use in lactating mothers should be avoided.
Drug-Drug Interactions
Critical
Critical
Drug-Drug Interactions
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Critical
How does the drug interact with Isolazine Tablet:
Taking Avanafil with Isolazine Tablet can cause low blood pressure.
How to manage the interaction:
Taking Isolazine Tablet with Avanafil is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, priapism in males (persistent and painful erection unrelated to sexual activity). Do not discontinue any medications without consulting a doctor.
Taking Avanafil with Isolazine Tablet can cause low blood pressure.
How to manage the interaction:
Taking Isolazine Tablet with Avanafil is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, priapism in males (persistent and painful erection unrelated to sexual activity). Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Isolazine Tablet:
Coadministration of Isolazine Tablet and Sildenafil can increase the risk of low blood pressure.
How to manage the interaction:
Taking Isolazine Tablet and Sildenafil together is generally avoided as it can lead to an interaction, it can be taken only if advised by your doctor. However, if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, and priapism (prolonged and painful erection unrelated to sexual activity) contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Coadministration of Isolazine Tablet and Sildenafil can increase the risk of low blood pressure.
How to manage the interaction:
Taking Isolazine Tablet and Sildenafil together is generally avoided as it can lead to an interaction, it can be taken only if advised by your doctor. However, if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, and priapism (prolonged and painful erection unrelated to sexual activity) contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Critical
How does the drug interact with Isolazine Tablet:
Taking Tadalafil with Isolazine Tablet can increase the risk or severity of low blood pressure.
How to manage the interaction:
Taking Isolazine Tablet with Tadalafil is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, or heart palpitations. Do not discontinue any medications without consulting a doctor.
Taking Tadalafil with Isolazine Tablet can increase the risk or severity of low blood pressure.
How to manage the interaction:
Taking Isolazine Tablet with Tadalafil is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, or heart palpitations. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Isolazine Tablet:
Taking Riociguat with Isolazine Tablet may lead to excessively low blood pressure.
How to manage the interaction:
Taking Isolazine Tablet with Riociguat is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, priapism in males (persistent and painful erection unrelated to sexual activity). Do not discontinue any medications without consulting a doctor.
Taking Riociguat with Isolazine Tablet may lead to excessively low blood pressure.
How to manage the interaction:
Taking Isolazine Tablet with Riociguat is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, priapism in males (persistent and painful erection unrelated to sexual activity). Do not discontinue any medications without consulting a doctor.
How does the drug interact with Isolazine Tablet:
Taking Isolazine Tablet with chloroprocaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).
How to manage the interaction:
Although taking Isolazine Tablet and chloroprocaine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitations, anxiety, or confusion. Do not stop using any medications without consulting doctor.
Taking Isolazine Tablet with chloroprocaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).
How to manage the interaction:
Although taking Isolazine Tablet and chloroprocaine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitations, anxiety, or confusion. Do not stop using any medications without consulting doctor.
How does the drug interact with Isolazine Tablet:
Coadministration of Isolazine Tablet and cabergoline may decrease your blood pressure.
How to manage the interaction:
Co-administration of Isolazine Tablet with Cabergoline can result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these signs - headache, dizziness, feeling lightheaded, or fainting, contact your doctor immediately. Do not stop using any medications without talking to your doctor.
Coadministration of Isolazine Tablet and cabergoline may decrease your blood pressure.
How to manage the interaction:
Co-administration of Isolazine Tablet with Cabergoline can result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these signs - headache, dizziness, feeling lightheaded, or fainting, contact your doctor immediately. Do not stop using any medications without talking to your doctor.
How does the drug interact with Isolazine Tablet:
Taking Isolazine Tablet with lidocaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).
How to manage the interaction:
Although taking Isolazine Tablet and lidocaine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
Taking Isolazine Tablet with lidocaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).
How to manage the interaction:
Although taking Isolazine Tablet and lidocaine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
Isosorbide dinitrateRopivacaine
Severe
How does the drug interact with Isolazine Tablet:
Taking Isolazine Tablet with ropivacaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).
How to manage the interaction:
Although taking Isolazine Tablet and ropivacaine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
Taking Isolazine Tablet with ropivacaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).
How to manage the interaction:
Although taking Isolazine Tablet and ropivacaine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
How does the drug interact with Isolazine Tablet:
Taking Isolazine Tablet with levobupivacaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).
How to manage the interaction:
Although taking Isolazine Tablet and levobupivacaine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
Taking Isolazine Tablet with levobupivacaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).
How to manage the interaction:
Although taking Isolazine Tablet and levobupivacaine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
Isosorbide dinitrateSodium nitrite
Severe
How does the drug interact with Isolazine Tablet:
Taking Isolazine Tablet with sodium nitrite may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).
How to manage the interaction:
Although taking Isolazine Tablet and sodium nitrite together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
Taking Isolazine Tablet with sodium nitrite may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).
How to manage the interaction:
Although taking Isolazine Tablet and sodium nitrite together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
Drug-Food Interactions
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
Drug-Food Interactions
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Diet & Lifestyle Advise
- Follow a cholesterol-lowering diet.
- Consume low salt and a low-fat diet.
- Exercise regularly. It helps in maintaining proper weight and lowers cholesterol.
- Limit salt and sugar intake.
- Avoid smoking and alcohol consumption.
- Choose healthy fats and cut down on trans fat.
- Include omega-3 fatty acids, fibre-rich food, fruits, and vegetables.
- Get active by doing physical activities such as swimming, brisk walking, or jogging. Take the stairs instead of elevators/lifts.
Habit Forming
No
Therapeutic Class
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Alcohol
Unsafe
Consuming alcohol with the Isolazine Tablet is not advisable as it may cause unpleasant side effects, or you may become more sensitive to the effects of alcohol.
Pregnancy
Consult your doctor
Isolazine Tablet is not recommended during pregnancy. Please discuss with the doctor if you have any concerns.
Breast Feeding
Consult your doctor
Isolazine Tablet is not recommended during nursing. Please discuss with the doctor if you have any concerns.
Driving
Unsafe
Isolazine Tablet may cause dizziness in some people, so it may affect your ability to drive.
Liver
Caution
Isolazine Tablet to be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.
Kidney
Caution
Isolazine Tablet to be taken with caution, especially if you have a history of kidney disease. The dose may have to be adjusted by your doctor.
Children
Unsafe
The safety and effectiveness of Isolazine Tablet in children have not been established.
Heart
Caution
Isolazine Tablet can be used in heart patients if prescribed by the physician in heart failure patients. Please consult your physician if you have any concerns.
Geriatrics
Caution
Exercise caution while giving Isolazine Tablet in geriatric patients. Close monitoring of the individual is required.
FAQs
Country of origin
India
Manufacturer/Marketer address
Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India
Country of Origin: India
Other Info - ISO0247
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