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  3. Isordil-10 Tablet 10's

Isordil-10 Tablet 10's, Pack of 10 TABLETS
Isordil-10 Tablet 10's, Pack of 10 TABLETS
Isordil-10 Tablet 10's, Pack of 10 TABLETS
Isordil-10 Tablet 10's, Pack of 10 TABLETS
Isordil-10 Tablet 10's, Pack of 10 TABLETS
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Isordil-10 Tablet is used in the prevention of angina (heart-related chest pain) or heart failure. It contains Isosorbide dinitrate, which works by dilating, relaxing, and widening the constricted blood vessels, thereby increasing the blood and oxygen supply to the heart. Thus, it effectively helps prevent the risk of future heart attack and stroke in the future, especially in high blood pressure patients. It may cause common side effects such as headache (during initial days of therapy) and flushing (reddening of the skin, especially the face). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

ISOSORBIDE DINITRATE-10MG

Manufacturer/Marketer :

Ipca Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Isordil-10 Tablet

Isordil-10 Tablet belongs to the class of blood pressure-lowering medications called ‘nitrate vasodilators’ used in the prevention of angina (heart-related chest pain) or heart failure. Angina pectoris (angina) is chest pain occurring due to reduced blood flow to the heart (coronary artery disease). It occurs when the blood vessels supplying the heart are blocked or narrowed.

Isordil-10 Tablet contains ‘isosorbide dinitrate’, which works by dilating, relaxing, and widening the constricted blood vessels, thereby increasing the blood and oxygen supply to the heart. Thus, it effectively helps prevent the risk of future heart attack and stroke in the future, especially in high blood pressure patients. 

Take Isordil-10 Tablet as prescribed. Your doctor will advise you on how often you take Isordil-10 Tablet based on your medical condition. The common side-effects of Isordil-10 Tablet are headache (during initial days of therapy) and flushing (reddening of the skin, especially the face). These side effects usually disappear without requiring medical attention. However, consult your doctor immediately if these effects persist or worsen.

Do not take it if you are allergic to ‘isosorbide dinitrate’ or any of its ingredients. Do not use in patients with severe heart failure, severe hypotension (low blood pressure), bleeding in the brain, severe dehydration, heart valve problems, progressive heart failure due to chronic lung disease, severe anemia (low levels of iron), and severe hypoxemia (low levels of oxygen in the blood). Inform your doctor if you have an underactive thyroid gland, glaucoma (an eye condition), or head injury. Inform your doctor if you are taking other prescription or non-prescription medicines, especially medicines used to treat erectile dysfunction in men. Isordil-10 Tablet contains lactose, so inform your doctor if you have an intolerance to some sugars. Also, inform your doctor if you are pregnant or breastfeeding.

Uses of Isordil-10 Tablet

Isordil-10 Tablet is used for the treatment of angina (heart-related chest pain). The detailed uses of Isordil-10 Tablet are as follows: <br/>• Angina pectoris treatment: Isordil-10 Tablet helps to relieve angina pectoris symptoms by widening blood vessels and improving blood flow to the heart, reducing chest pain.<br/>• Prevention of angina attacks: Isordil-10 Tablet can be administered to prevent the occurrence of angina attacks, especially during physical activity or stressful situations.<br/>• Management of heart failure: Isordil-10 Tablet helps to manage heart failure symptoms by reducing the heart's workload and improving blood flow, often used alongside other medications for better heart function.<br/>• Vasodilation: Isordil-10 Tablet works by causing vasodilation, widening blood vessels, which reduces blood pressure and decreases the heart's workload, providing relief.<br/>• Post-myocardial infarction care: Isordil-10 Tablet helps to improve oxygen supply to the heart and reduces cardiac workload in post-heart attack patients, supporting recovery and potentially lowering the risk of future heart issues.<br/>

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Directions for Use

• Isordil-10 Tablet can be taken on an empty stomach, at least 30 minutes before or 2 hours after food as advised by your doctor.• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Swallow Isordil-10 Tablet as a whole with a glass of water.• Do not chew, crush or break it.

Medicinal Benefits

Isordil-10 Tablet contains ‘isosorbide dinitrate’, which is a ‘nitrate’ and a vasodilator. It acts by dilating and relaxing the constricted blood vessels due to increased blood pressure (hypertension). This effect helps in improving the blood and oxygen supply to the heart, thus decreasing the risk of angina or heart-related chest pain. Thus, Isordil-10 Tablet prevents the risk of chest pain in heart conditions like coronary artery disease.

How Isordil-10 Tablet Works

Isordil-10 Tablet contains ‘isosorbide dinitrate’, which works by dilating, relaxing, and widening the constricted blood vessels, thereby increasing the blood and oxygen supply to the heart. Thus, it effectively helps prevent the risk of future heart attack and stroke in the future, especially in high blood pressure patients.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Isordil-10 Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
  • Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
  • Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
  • Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
  • Gently massage the swollen area with firm but not painful pressure.
  • Keep the swollen area clean and moisturized to prevent injury and infection.
  • Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
  • If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

What if I have taken an overdose of Isordil-10 Tablet

Do not take more than the prescribed dose of Isordil-10 Tablet as it may cause overdose. The symptoms of overdose include fever, confusion, severe throbbing headache, fast or pounding heartbeats, severe dizziness, nausea, vomiting, stomach pain, vision problems, bloody diarrhoea, stomach pain, sweating, trouble breathing, fainting, cold or clammy skin, and seizures (fits). If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Isordil-10 Tablet if you are allergic to ‘isosorbide dinitrate’ or its contents. Do not take it if you have severe low blood pressure, bleeding or increased pressure in the brain, severe dehydration, heart valve problems, inflammation of the heart wall, high blood pressure due to long-term lung disease, and severe anemia. Before taking Isordil-10 Tablet , inform your doctor if you have glaucoma (increased pressure in the eye), glucose 6 phosphate dehydrogenase deficiency (a type of anemia), underactive thyroid (hypothyroidism), kidney or liver problems, head injury, hypothermia (low body temperature), or intolerance to some sugars. This medicine should not be used with medicines used for erectile dysfunction like sildenafil or tadalafil. Inform your doctor if you are pregnant or breastfeeding.

Drug-Drug Interactions

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Isosorbide dinitrateAvanafil
Critical
Isosorbide dinitrateRiociguat
Critical

Drug-Drug Interactions

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Isosorbide dinitrateAvanafil
Critical
How does the drug interact with Isordil-10 Tablet:
Taking Avanafil with Isordil-10 Tablet can cause low blood pressure.

How to manage the interaction:
Taking Isordil-10 Tablet with Avanafil is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, priapism in males (persistent and painful erection unrelated to sexual activity). Do not discontinue any medications without consulting a doctor.
Isosorbide dinitrateRiociguat
Critical
How does the drug interact with Isordil-10 Tablet:
Taking Riociguat with Isordil-10 Tablet may lead to excessively low blood pressure.

How to manage the interaction:
Taking Isordil-10 Tablet with Riociguat is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, priapism in males (persistent and painful erection unrelated to sexual activity). Do not discontinue any medications without consulting a doctor.
Isosorbide dinitrateTadalafil
Critical
How does the drug interact with Isordil-10 Tablet:
Taking Tadalafil with Isordil-10 Tablet can increase the risk or severity of low blood pressure.

How to manage the interaction:
Taking Isordil-10 Tablet with Tadalafil is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, or heart palpitations. Do not discontinue any medications without consulting a doctor.
Isosorbide dinitrateSildenafil
Critical
How does the drug interact with Isordil-10 Tablet:
Coadministration of Isordil-10 Tablet and Sildenafil can increase the risk of low blood pressure.

How to manage the interaction:
Taking Isordil-10 Tablet and Sildenafil together is generally avoided as it can lead to an interaction, it can be taken only if advised by your doctor. However, if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, and priapism (prolonged and painful erection unrelated to sexual activity) contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Isosorbide dinitrateBupivacaine
Severe
How does the drug interact with Isordil-10 Tablet:
Combining Bupivacaine with Isordil-10 Tablet can increase the risk of methemoglobinemia(a rare condition that can lead to oxygen deprivation in tissues and vital organs due to reduced oxygen-carrying capacity of the blood).

How to manage the interaction:
Co-administration of Bupivacaine with Isordil-10 Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like grey discolouration of the skin, abnormal blood colouration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, confusion, consult a doctor right away. Do not stop using any medications without a doctor's advice.
Isosorbide dinitrateChloroprocaine
Severe
How does the drug interact with Isordil-10 Tablet:
Taking Isordil-10 Tablet with chloroprocaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking Isordil-10 Tablet and chloroprocaine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitations, anxiety, or confusion. Do not stop using any medications without consulting doctor.
Isosorbide dinitrateCabergoline
Severe
How does the drug interact with Isordil-10 Tablet:
Taking Isordil-10 Tablet with cabergoline can increase the effects of Cabergoline.

How to manage the interaction:
Although taking Isordil-10 Tablet and cabergoline together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. Do not stop using any medications without consulting doctor.
Isosorbide dinitrateSodium nitrite
Severe
How does the drug interact with Isordil-10 Tablet:
Taking Isordil-10 Tablet with sodium nitrite may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking Isordil-10 Tablet and sodium nitrite together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
Isosorbide dinitrateLidocaine
Severe
How does the drug interact with Isordil-10 Tablet:
Taking Isordil-10 Tablet with lidocaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking Isordil-10 Tablet and lidocaine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
Isosorbide dinitrateErgotamine
Severe
How does the drug interact with Isordil-10 Tablet:
Taking Isordil-10 Tablet together with ergotamine can increase the effects of ergotamine.

How to manage the interaction:
Although taking Isordil-10 Tablet and ergotamine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience an irregular heartbeat, nausea, vomiting, weakness, or coldness, numbness, chest pain or pain in the hands, feet, arms, or legs. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat plenty of fresh fruits and vegetables. Choose whole grains rather than refined or polished grains. Choose lean proteins, such as skinless chicken and fish. Choose non-fat or low-fat dairy products.
  • Do not take food containing high levels of sodium (salt).
  • Drink plenty of fluids to prevent dehydration. 
  • Maintain a normal weight. Shed excess weight by exercising regularly for at least 30 min a day.
  • Manage stress.
  • Limit alcohol intake and quit smoking.

Habit Forming

No

Therapeutic Class

ANTIANGINALS

Isordil-10 Tablet Substitute

Substitutes safety advice
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Alcohol

Caution

Alcohol may worsen the condition by increasing the risk of side-effects. So, do not consume alcohol.

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Pregnancy

Caution

Isordil-10 Tablet is a category C medicine and may cause harm to the fetus. It should be used in pregnant women if clinically needed and when benefits outweigh the risks.

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Breast Feeding

Caution

Isordil-10 Tablet should be used with caution in breastfeeding mothers.

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Driving

Caution

Isordil-10 Tablet may cause dizziness and affect your ability to drive. So, avoid driving or operating heavy machinery while using Isordil-10 Tablet .

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Liver

Caution

Isordil-10 Tablet should be used with caution in patients with liver diseases. Dose adjustments may be required in severe liver disease patient.

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Kidney

Caution

Isordil-10 Tablet should be used with caution in patients with kidney diseases. Dose adjustments may be required.

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Children

Caution

$should not be used in children unless clinically needed. Dose adjustments may be necessary.

FAQs

Isordil-10 Tablet is used to prevent angina (heart-related chest pain) or heart failure.

Isordil-10 Tablet is a &amp;#039;vasodilator&amp;#039; and can prevent angina effectively. It works by relaxing the muscles of blood vessels. It helps to dilate the narrowed blood vessels resulting in increased blood and oxygen supply to the heart. This prevents heart-related chest pain known as angina.

Isordil-10 Tablet is used to prevent angina attacks. However, it cannot stop the angina attack that has already started as it works very slowly (delayed onset of action).

Isordil-10 Tablet may decrease blood pressure (hypotension). So it should not be used in patients with severe hypotension.

Lisinopril is a medication used to treat high blood pressure. Using Isordil-10 Tablet with lisinopril may cause a decrease in blood pressure (hypotension). So, consult your doctor before taking other medications while using Isordil-10 Tablet .

Use of Isordil-10 Tablet together with sildenafil is not recommended as it may cause a sudden decrease in blood pressure leading to loss of consciousness, even leading to coma stage.

Isordil-10 Tablet is given for heart-related chest pain (angina), a life-long or chronic disease, especially in high blood pressure patients and coronary heart disease (CAD). So, do not stop taking Isordil-10 Tablet even if you feel better. It would be best if you took Isordil-10 Tablet until your doctor tells you to stop.

Isordil-10 Tablet is sometimes used only when needed, you may not be on a dosing schedule. If you are on a schedule, take the missed dose as soon as you remember or if it&amp;#039;s nearly time for your next dose, skip your missed dose. Do not use extra medicine to make up a missed dose.

Isordil-10 Tablet is not typically used to treat a heart attack. However, it can help manage angina, which can be a symptom of an underlying heart condition. In the event of a heart attack, it's crucial to seek immediate medical attention. Call emergency services or go to the hospital right away.

Isordil-10 Tablet works by relaxing and widening blood vessels, which can lead to reduced blood pressure and increased blood flow. However, this can also trigger a reflexive response, causing increased heart rate (tachycardia). As a result, while Isordil-10 Tablet can help alleviate angina symptoms, it may not lower heart rate and might even increase it in some cases.

Yes, Isordil-10 Tablet can lower blood pressure. It works by relaxing and widening blood vessels, which decreases the pressure on the heart and allows blood to flow more easily. This can result in a reduction in blood pressure. Please consult your doctor before taking Isordil-10 Tablet .

Country of origin

India

Manufacturer/Marketer address

142 AB, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra.
Other Info - ISO0019

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 6, 2025 | 10:58 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.5795.pdf

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