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  3. Itralase 100 Capsule 15's

Itralase 100 Capsule 15's, Pack of 15 CapsuleS
Itralase 100 Capsule 15's, Pack of 15 CapsuleS
Itralase 100 Capsule 15's, Pack of 15 CapsuleS
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Itralase 100 Capsule is an antifungal medicine used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. It contains Itraconazole, which works by killing fungi. Some people may experience side effects such as nausea, headache, diarrhoea, tiredness, cough, cold, throat pain, back pain and stomach pain. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

ITRACONAZOLE-100MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Itralase 100 Capsule

Itralase 100 Capsule is an antifungal medicine used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. Fungal infection is a disease in which a fungus attacks the tissue and causes infection. Fungal infections may be contagious (spread from one person to another).

Itralase 100 Capsule contains Itraconazole, an antifungal that works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents.Thus, it causes the main components of fungal cells to leak out, killing fungi and clearing the fungal infection.

Take Itralase 100 Capsule as prescribed. Your doctor will advise you on how often you take Itralase 100 Capsule based on your medical condition. Some people may experience nausea, headache, diarrhoea, tiredness, cough, cold, throat pain, back pain and stomach pain. Most of these side effects of Itralase 100 Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Itralase 100 Capsule or any other medicines, please tell your doctor. Itralase 100 Capsule is a pregnancy category C drug and may cause harm to the unborn baby. However, if you are pregnant, planning for pregnancy or a nursing mother, it is advised to consult a doctor before using Itralase 100 Capsule . Do not take Itralase 100 Capsule if you have or have heart failure, as it may cause severe life-threatening adverse effects. If you have kidney, liver, heart or lung problems, inform your doctor before taking Itralase 100 Capsule . Avoid taking fentanyl (a strong opioid narcotic medicine) with Itralase 100 Capsule as it may cause severe breathing problems and can even lead to death. If you experience numbness or tingling in your hands or feet, stop taking Itralase 100 Capsule and consult your doctor immediately as they might be symptoms of nerve damage.

Uses of Itralase 100 Capsule

Itralase 100 Capsule is used in the treatment of fungal infections. The detailed uses of Itralase 100 Capsule are as follows:
• Yeast Infection Treatment: Itralase 100 Capsule is commonly used to combat vaginal yeast infections caused by the Candida fungus.
• Fungal Infection Management: Itralase 100 Capsule effectively treats various systemic fungal infections, especially in individuals with weakened immune systems.
• Preventive Care: Doctors may prescribe Itralase 100 Capsule to prevent fungal infections in patients undergoing chemotherapy or those prone to such infections due to immune deficiencies.
• Oral Thrush Treatment: Itralase 100 Capsule is also useful in managing oral candidiasis (thrush), a fungal overgrowth in the mouth caused by Candida.

Directions for Use

Tablet: Take it with food to avoid stomach upset or as advised by the doctor. Swallow the whole tablet with a glass of water. Do not break, crush or chew it. If you are taking any stomach acid suppressor or have achlorhydria (stomach does not produce hydrochloric acid), take Itralase 100 Capsule with cola.

Medicinal Benefits

Itralase 100 Capsule is an antifungal used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Itralase 100 Capsule inhibits the production of ergosterol (a main component of the cell membranes of fungi). This weakens and damages the fungal cell membranes, causing the main components of fungal cells to leak out. Thus, it kills fungi and clears the fungal infection.

How Itralase 100 Capsule Works

Itralase 100 Capsule contains Itraconazole, an antifungal that works by inhibiting the production of ergosterol (a main component of the cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents.Thus, it causes the main components of fungal cells to leak out, killing fungi and clearing the fungal infection.

Storage

Store in a cool and dry place away from sunlight
Side effects of Itralase 100 Capsule
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Eat potassium-rich foods like avocados, bananas, spinach, and potatoes.
  • Stay hydrated by drinking plenty of water.
  • Exercise regularly and maintain healthy weight.
  • Manage stress.
  • Prioritize 7-9 hours of sleep each night to help your body and mind recharge.
  • Avoid smoking and limit intake of caffeine.
  • Practice stress-reducing activities like meditation, yoga, or deep breathing to help calm your mind and body.
  • Avoid stimulants and illegal drugs.
  • Call your doctor if it worsens.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

What if I have taken an overdose of Itralase 100 Capsule

Do not take more than the prescribed dose of Itralase 100 Capsule as it may cause an overdose. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

If you are known to be allergic to Itralase 100 Capsule or any other medicines, please tell your doctor. Itralase 100 Capsule is a pregnancy category C drug and may cause harm to the unborn baby. However, if you are pregnant, planning for pregnancy, or are a nursing mother, it is advised to consult a doctor before using Itralase 100 Capsule . Avoid taking fentanyl (a strong opioid pain killer narcotic medicine) with Itralase 100 Capsule , as it may cause severe breathing problems and can even lead to death. Do not take Itralase 100 Capsule if you have had heart failure, as it may cause severe, life-threatening adverse effects. If you experience a yellow colour change of your eyes or skin, dark coloured urine, stomach pain, pale stools, loss of appetite, unusual tiredness, vomiting or nausea, stop taking Itralase 100 Capsule and consult a doctor immediately, as they might be symptoms of liver failure. If you have kidney, liver, heart, or lung problems, inform your doctor before taking Itralase 100 Capsule .

Drug-Drug Interactions

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ItraconazoleIsavuconazole
Critical
ItraconazoleTolvaptan
Critical

Drug-Drug Interactions

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ItraconazoleIsavuconazole
Critical
How does the drug interact with Itralase 100 Capsule:
The blood levels and effects of Isavuconazole may be significantly enhanced by taking Itralase 100 Capsule along with it.

How to manage the interaction:
Co-administration of Isavuconazole and Itralase 100 Capsule can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like nausea, vomiting, or diarrhoea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ItraconazoleTolvaptan
Critical
How does the drug interact with Itralase 100 Capsule:
Co-administration of Tolvaptan and Itralase 100 Capsule may significantly raise Tolvaptan blood levels and effects.

How to manage the interaction:
There may be a possibility of interaction between Tolvaptan and Itralase 100 Capsule, but it can be taken if prescribed by a doctor. If you notice any of these signs -difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures, call a doctor right away. Do not stop using any medications without a doctor's advice.
ItraconazoleErgotamine
Critical
How does the drug interact with Itralase 100 Capsule:
The blood levels and effects of ergotamine may be greatly increased when combined with Itralase 100 Capsule.

How to manage the interaction:
Ergotamine and Itralase 100 Capsule may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you experience a severe headache, shortness of breath, blurred vision, confusion, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of the fingers or toes, pale or cold skin, or chest pain or tightness. Without first consulting your doctor, never stop taking medicines.
ItraconazoleAvanafil
Critical
How does the drug interact with Itralase 100 Capsule:
Co-administartion of avanafil and Itralase 100 Capsule may considerably raise the blood levels of Avanafil.

How to manage the interaction:
Although combining avanafil and Itralase 100 Capsule may possibly lead to an interaction, they can be taken if prescribed by a doctor. Consult a physician if you develop any side effects, including priapism (prolonged and painful erection unrelated to sexual activity), low blood pressure, fainting, visual problems, including loss of vision, ringing in the ears, hearing loss, and low blood pressure. Without consulting a doctor, never stop taking any medication.
ItraconazoleEplerenone
Critical
How does the drug interact with Itralase 100 Capsule:
The blood levels and effects of eplerenone may be greatly increased when combined with Itralase 100 Capsule.

How to manage the interaction:
Although there is a possible interaction between Eplerenone and Itralase 100 Capsule, it is not recommended; they can be taken if prescribed by a doctor. Consult a doctor if you have complications such as hyperkalemia (high blood potassium), which in extreme circumstances can result in kidney problems, muscle paralysis, and an irregular heartbeat. Without first consulting your doctor, never stop taking medicines.
ItraconazoleSimvastatin
Critical
How does the drug interact with Itralase 100 Capsule:
Simvastatin's blood levels and effects may be greatly increased when combined with Itralase 100 Capsule.

How to manage the interaction:
Simvastatin and Itralase 100 Capsule may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you have side effects such unexplained pain in the muscles or tenderness, muscle weakness, fever or flu-like symptoms, or dark urine. Without consulting a doctor, never stop taking any medication.
ItraconazoleAlprazolam
Critical
How does the drug interact with Itralase 100 Capsule:
Alprazolam's blood levels may be significantly raised when combined with Itralase 100 Capsule.

How to manage the interaction:
Although combining Alprazolam and Itralase 100 Capsule may lead to an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you get extremely drowsy and your breathing becomes slow. Without consulting a doctor, never stop taking any medication.
ItraconazoleTicagrelor
Critical
How does the drug interact with Itralase 100 Capsule:
The blood levels and effects of ticagrelor may be greatly increased when combined with Itralase 100 Capsule.

How to manage the interaction:
Itralase 100 Capsule and ticagrelor may interact, however if prescribed by a physician, they can be used together. While receiving therapy, you should consult a doctor if you develop any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Without consulting a doctor, never stop taking any medication.
ItraconazoleTriazolam
Critical
How does the drug interact with Itralase 100 Capsule:
Co-administration of Triazolam and Itralase 100 Capsule may significantly increase the levels of Triazolam.

How to manage the interaction:
Although combining Triazolam and Itralase 100 Capsule may possibly lead to an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you get extremely drowsy and your breathing becomes slow. Without consulting a doctor, never stop taking any medication.
ItraconazoleSolifenacin
Critical
How does the drug interact with Itralase 100 Capsule:
The blood levels and effects of solifenacin may be greatly increased when combined with Itralase 100 Capsule.

How to manage the interaction:
Solifenacin and Itralase 100 Capsule may interact, however, if recommended by a physician, they are safe to consume. Consult a doctor if you feel sleepy, or uneasy, have an irregular heartbeat, have blurry vision, have trouble urinating, have a dry mouth, a headache, have digestive problems, or have constipation. Without consulting a doctor, never stop taking any medication.

Drug-Food Interactions

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ITRACONAZOLE-100MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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ITRACONAZOLE-100MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consuming Grapefruit, Grapefruit juice with Itralase 100 Capsule may impair the absorption of Itralase 100 Capsule, resulting in decreased antifungal effects. Avoid consuming Grapefruit and grapefruit juice with Itralase 100 Capsule.

Diet & Lifestyle Advise

  • Regularly change your socks and wash your feet. Avoid shoes that make your feet sweaty and hot.
  • Don't walk barefoot in wet places such as changing rooms and gym showers to prevent fungal infections.
  • Do not scratch the affected area of skin, as it can spread the infection to other body parts.
  • Avoid sharing towels, combs, bedsheets, shoes or socks with others.
  • Wash your bed sheets and towels regularly.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS

Itralase 100 Capsule Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol with Itralase 100 Capsule as it may increase the risk of liver problems and other adverse effects.

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Pregnancy

Unsafe

Itralase 100 Capsule is category C pregnancy drug and is unsafe for pregnant women as it may cause harm to the unborn baby. Therefore, inform your doctor if you are pregnant or planning for pregnancy before taking Itralase 100 Capsule .

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Breast Feeding

Caution

Itralase 100 Capsule is excreted in human milk and may harm the baby. Therefore, Itralase 100 Capsule is given to breastfeeding mothers only if doctor thinks benefits are greater than risks.

bannner image

Driving

Caution

Itralase 100 Capsule may cause dizziness, hearing loss, double or blurred vision in some people. Therefore, drive only if you alert after taking Itralase 100 Capsule .

bannner image

Liver

Caution

Take Itralase 100 Capsule with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

bannner image

Kidney

Caution

Take Itralase 100 Capsule with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

bannner image

Children

Unsafe

Itralase 100 Capsule is not recommended for children below 12 years as the safety and effectiveness were not established.

Have a query?

FAQs

Itralase 100 Capsule is used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. It works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby killing fungi and clearing the fungal infection.

You are not recommended to take Itralase 100 Capsule with simvastatin as co-administration of these two medicines may cause muscle weakness, unexplained muscle pain or tenderness, dark coloured urine, fever or flu symptoms. However, please consult a doctor before using Itralase 100 Capsule with other medicines.

No, Itralase 100 Capsule is not recommended for use during pregnancy as it may cause harm to the fetus. Also, it is advised to use effective contraceptive measures while taking Itralase 100 Capsule and after 2 months of stopping treatment with Itralase 100 Capsule . However, please inform your doctor if you are pregnant, planning for pregnancy or breastfeeding before taking Itralase 100 Capsule .

Itralase 100 Capsule may cause temporary or permanent hearing loss in some people. It is not necessary for everyone taking Itralase 100 Capsule to experience this adverse effect. However, if you notice any changes in hearing, stop taking Itralase 100 Capsule and consult a doctor immediately.

You are advised to take antacids (drugs used to reduce acid in the stomach) such as omeprazole, pantoprazole and esomeprazole at least 1 hour before or 2 hours after taking Itralase 100 Capsule as co-administration of these medicines at the same time may reduce the effectiveness of Itralase 100 Capsule because antacids decrease the absorption and blood levels of Itralase 100 Capsule . However, please consult a doctor before taking other medicines with Itralase 100 Capsule .

Yes, fungal infection is a contagious skin condition which spreads from one person to another through direct skin to skin contact or by contact with contaminated soil or surfaces and infected animals. Therefore, it is recommended to avoid close direct contact until the infection is clear and avoid sharing things with the infected person as it can also spread the infection.

You are not recommended to stop taking Itralase 100 Capsule without consulting your doctor as it may cause recurring infection. Therefore, take Itralase 100 Capsule for as long as your doctor has prescribed it, and if you experience any difficulty while taking Itralase 100 Capsule , please consult your doctor.

Inform your doctor if you are sexually active and discuss effective contraception methods. Itralase 100 Capsule may reduce the effectiveness of oral contraceptive pills. Thus, you are advised to use barrier methods of contraception like condoms, if you are taking Itralase 100 Capsule .

Inform the doctor about your detailed medical and surgical history, if you have liver, kidney or heart disease or fits and if you are pregnant, breastfeeding or planning pregnancy. Inform your doctor if you are taking any other medicines including supplements or herbal products as Itralase 100 Capsule may interact with other medicines. Also, let your doctor know if you are stopping any medicine.

Itralase 100 Capsule contains Itraconazole, an antifungal that works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, it causes the main components of fungal cells to leak out, kill fungi, and clear the fungal infection.

Yes, you should swallow the capsule whole with a glass of water. Do not crush, chew or break it.

The side effects of Itralase 100 Capsule include nausea, headache, diarrhoea, stomach pain, fatigue (overtiredness), back pain, cough, and sore throat. If these side effects persist or worsen, please consult your doctor.

If you have taken overdose of Itralase 100 Capsule , please consult your doctor immediately.

Store Itralase 100 Capsule at room temperature. Protect from light and moisture. Keep out of reach and sight of children.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - ITR0108

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

May 2, 2025 | 1:20 PM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/022484s000lbl.pdf
  2. https://mims.com/malaysia/drug/info/itraconazole/patientmedicine/itraconazole%2B-%2Boral
  3. https://www.drugs.com/mtm/itraconazole.html
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