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  3. Itratuf Oral Solution 100 ml

Itratuf Oral Solution 100 ml, Pack of 1 ORAL SOLUTION
Itratuf Oral Solution 100 ml, Pack of 1 ORAL SOLUTION
Itratuf Oral Solution 100 ml, Pack of 1 ORAL SOLUTION
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Itratuf Oral Solution is an antifungal medicine used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. It contains Itraconazole, which works by killing fungi. Some people may experience side effects such as nausea, headache, diarrhoea, tiredness, cough, cold, throat pain, back pain and stomach pain. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

ITRACONAZOLE-10MG

Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Itratuf Oral Solution

Itratuf Oral Solution is an antifungal medicine used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. Fungal infection is a disease in which a fungus attacks the tissue and causes infection. Fungal infections may be contagious (spread from one person to another).

Itratuf Oral Solution contains Itraconazole, an antifungal that works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents.Thus, it causes the main components of fungal cells to leak out, killing fungi and clearing the fungal infection.

Take Itratuf Oral Solution as prescribed. Your doctor will advise you on how often you take Itratuf Oral Solution based on your medical condition. Some people may experience nausea, headache, diarrhoea, tiredness, cough, cold, throat pain, back pain and stomach pain. Most of these side effects of Itratuf Oral Solution do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Itratuf Oral Solution or any other medicines, please tell your doctor. Itratuf Oral Solution is a pregnancy category C drug and may cause harm to the unborn baby. However, if you are pregnant, planning for pregnancy or a nursing mother, it is advised to consult a doctor before using Itratuf Oral Solution . Do not take Itratuf Oral Solution if you have or have heart failure, as it may cause severe life-threatening adverse effects. If you have kidney, liver, heart or lung problems, inform your doctor before taking Itratuf Oral Solution . Avoid taking fentanyl (a strong opioid narcotic medicine) with Itratuf Oral Solution as it may cause severe breathing problems and can even lead to death. If you experience numbness or tingling in your hands or feet, stop taking Itratuf Oral Solution and consult your doctor immediately as they might be symptoms of nerve damage.

Uses of Itratuf Oral Solution

Itratuf Oral Solution is used in the treatment of fungal infections. The detailed uses of Itratuf Oral Solution are as follows:
• Yeast Infection Treatment: Itratuf Oral Solution is commonly used to combat vaginal yeast infections caused by the Candida fungus.
• Fungal Infection Management: Itratuf Oral Solution effectively treats various systemic fungal infections, especially in individuals with weakened immune systems.
• Preventive Care: Doctors may prescribe Itratuf Oral Solution to prevent fungal infections in patients undergoing chemotherapy or those prone to such infections due to immune deficiencies.
• Oral Thrush Treatment: Itratuf Oral Solution is also useful in managing oral candidiasis (thrush), a fungal overgrowth in the mouth caused by Candida.

Directions for Use

Tablet: Take it with food to avoid stomach upset or as advised by the doctor. Swallow the whole tablet with a glass of water. Do not break, crush or chew it. If you are taking any stomach acid suppressor or have achlorhydria (stomach does not produce hydrochloric acid), take Itratuf Oral Solution with cola.

Medicinal Benefits

Itratuf Oral Solution is an antifungal used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Itratuf Oral Solution inhibits the production of ergosterol (a main component of the cell membranes of fungi). This weakens and damages the fungal cell membranes, causing the main components of fungal cells to leak out. Thus, it kills fungi and clears the fungal infection.

How Itratuf Oral Solution Works

Itratuf Oral Solution contains Itraconazole, an antifungal that works by inhibiting the production of ergosterol (a main component of the cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents.Thus, it causes the main components of fungal cells to leak out, killing fungi and clearing the fungal infection.

Storage

Store in a cool and dry place away from sunlight
Side effects of Itratuf Oral Solution 100 ml
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Exercise for at least 30 minutes most days of the week.
  • Limit alcohol consumption.
  • Consider a low carbohydrate diet that limits grains, starchy vegetables and fruit. Include foods rich in protein and fat.
  • Avoid excess sugar, fatty foods and carbohydrates.
  • Aim for weight loss as it helps to improve cardiovascular health and minimize the risk of complications related to obesity.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

What if I have taken an overdose of Itratuf Oral Solution

Do not take more than the prescribed dose of Itratuf Oral Solution as it may cause an overdose. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

If you are known to be allergic to Itratuf Oral Solution or any other medicines, please tell your doctor. Itratuf Oral Solution is a pregnancy category C drug and may cause harm to the unborn baby. However, if you are pregnant, planning for pregnancy, or are a nursing mother, it is advised to consult a doctor before using Itratuf Oral Solution . Avoid taking fentanyl (a strong opioid pain killer narcotic medicine) with Itratuf Oral Solution , as it may cause severe breathing problems and can even lead to death. Do not take Itratuf Oral Solution if you have had heart failure, as it may cause severe, life-threatening adverse effects. If you experience a yellow colour change of your eyes or skin, dark coloured urine, stomach pain, pale stools, loss of appetite, unusual tiredness, vomiting or nausea, stop taking Itratuf Oral Solution and consult a doctor immediately, as they might be symptoms of liver failure. If you have kidney, liver, heart, or lung problems, inform your doctor before taking Itratuf Oral Solution .

Drug-Drug Interactions

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ItraconazoleSimvastatin
Critical
ItraconazoleFelodipine
Critical

Drug-Drug Interactions

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ItraconazoleSimvastatin
Critical
How does the drug interact with Itratuf Oral Solution 100 ml:
Simvastatin's blood levels and effects may be greatly increased when combined with Itratuf Oral Solution 100 ml.

How to manage the interaction:
Simvastatin and Itratuf Oral Solution 100 ml may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you have side effects such unexplained pain in the muscles or tenderness, muscle weakness, fever or flu-like symptoms, or dark urine. Without consulting a doctor, never stop taking any medication.
ItraconazoleFelodipine
Critical
How does the drug interact with Itratuf Oral Solution 100 ml:
The blood levels and effects of felodipine may be considerably increased by taking Itratuf Oral Solution 100 ml together with felodipine.

How to manage the interaction:
Although there is a possible interaction between felodipine and Itratuf Oral Solution 100 ml, they can be taken if prescribed by a doctor. Consult a physician if you have an irregular heartbeat, Edema (accumulation of fluid in hands or legs), or abnormally low blood pressure. Without first consulting a doctor, never stop taking medicines.
ItraconazoleTolvaptan
Critical
How does the drug interact with Itratuf Oral Solution 100 ml:
Co-administration of Tolvaptan and Itratuf Oral Solution 100 ml may significantly raise Tolvaptan blood levels and effects.

How to manage the interaction:
There may be a possibility of interaction between Tolvaptan and Itratuf Oral Solution 100 ml, but it can be taken if prescribed by a doctor. If you notice any of these signs -difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures, call a doctor right away. Do not stop using any medications without a doctor's advice.
ItraconazoleNisoldipine
Critical
How does the drug interact with Itratuf Oral Solution 100 ml:
The blood levels and effects of nisoldipine may be greatly increased when used with Itratuf Oral Solution 100 ml.

How to manage the interaction:
Nisoldipine and Itratuf Oral Solution 100 ml may interact, but if prescribed by a doctor, they can be used together. Consult a physician if you have symptoms that include an irregular heartbeat, accumulation of fluid in legs or hands, or abnormally low blood pressure. Without consulting a doctor, never stop taking any medication.
ItraconazoleDisopyramide
Critical
How does the drug interact with Itratuf Oral Solution 100 ml:
Coadministration of Itratuf Oral Solution 100 ml with Disopyramide can reduce the metabolism and increase the levels of Disopyramide in the body. This may increase the risk or severity of side effects like irregular heart rhythms.

How to manage the interaction:
Taking Itratuf Oral Solution 100 ml with Disopyramide together is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of headaches, dizziness, irritation, confusion, chest pain or tightness, swelling, fatigue, palpitations, shortness of breath, or constipation, you should contact your doctor immediately. Do not stop using any medications without talking to your doctor.
ItraconazoleColchicine
Critical
How does the drug interact with Itratuf Oral Solution 100 ml:
Coadministration of colchicine with Itratuf Oral Solution 100 ml may increase the blood levels of colchicine, increasing the risk of serious side effects.

How to manage the interaction:
Colchicine with Itratuf Oral Solution 100 ml can be taken if prescribed by a doctor, despite the possibility of an interaction. However, contact a doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop using any medications without first talking to your doctor.
ItraconazoleIsavuconazole
Critical
How does the drug interact with Itratuf Oral Solution 100 ml:
The blood levels and effects of Isavuconazole may be significantly enhanced by taking Itratuf Oral Solution 100 ml along with it.

How to manage the interaction:
Co-administration of Isavuconazole and Itratuf Oral Solution 100 ml can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like nausea, vomiting, or diarrhoea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ItraconazoleSilodosin
Critical
How does the drug interact with Itratuf Oral Solution 100 ml:
Coadministration of Itratuf Oral Solution 100 ml with Silodosin can increase the blood levels and effects of Silodosin, which may lead to side effects including extremely low blood pressure and increased heart rate.

How to manage the interaction:
Taking Itratuf Oral Solution 100 ml with Silodosin together is not recommended as it can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, or heart palpitation. Do not discontinue any medications without consulting a doctor.
ItraconazoleEplerenone
Critical
How does the drug interact with Itratuf Oral Solution 100 ml:
The blood levels and effects of eplerenone may be greatly increased when combined with Itratuf Oral Solution 100 ml.

How to manage the interaction:
Although there is a possible interaction between Eplerenone and Itratuf Oral Solution 100 ml, it is not recommended; they can be taken if prescribed by a doctor. Consult a doctor if you have complications such as hyperkalemia (high blood potassium), which in extreme circumstances can result in kidney problems, muscle paralysis, and an irregular heartbeat. Without first consulting your doctor, never stop taking medicines.
ItraconazoleTicagrelor
Critical
How does the drug interact with Itratuf Oral Solution 100 ml:
The blood levels and effects of ticagrelor may be greatly increased when combined with Itratuf Oral Solution 100 ml.

How to manage the interaction:
Itratuf Oral Solution 100 ml and ticagrelor may interact, however if prescribed by a physician, they can be used together. While receiving therapy, you should consult a doctor if you develop any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Without consulting a doctor, never stop taking any medication.

Drug-Food Interactions

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ITRACONAZOLE-10MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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ITRACONAZOLE-10MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consuming Grapefruit, Grapefruit juice with Itratuf Oral Solution 100 ml may impair the absorption of Itratuf Oral Solution 100 ml, resulting in decreased antifungal effects. Avoid consuming Grapefruit and grapefruit juice with Itratuf Oral Solution 100 ml.

Diet & Lifestyle Advise

  • Regularly change your socks and wash your feet. Avoid shoes that make your feet sweaty and hot.
  • Don't walk barefoot in wet places such as changing rooms and gym showers to prevent fungal infections.
  • Do not scratch the affected area of skin, as it can spread the infection to other body parts.
  • Avoid sharing towels, combs, bedsheets, shoes or socks with others.
  • Wash your bed sheets and towels regularly.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS

Itratuf Oral Solution Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol with Itratuf Oral Solution as it may increase the risk of liver problems and other adverse effects.

bannner image

Pregnancy

Unsafe

Itratuf Oral Solution is category C pregnancy drug and is unsafe for pregnant women as it may cause harm to the unborn baby. Therefore, inform your doctor if you are pregnant or planning for pregnancy before taking Itratuf Oral Solution .

bannner image

Breast Feeding

Caution

Itratuf Oral Solution is excreted in human milk and may harm the baby. Therefore, Itratuf Oral Solution is given to breastfeeding mothers only if doctor thinks benefits are greater than risks.

bannner image

Driving

Caution

Itratuf Oral Solution may cause dizziness, hearing loss, double or blurred vision in some people. Therefore, drive only if you alert after taking Itratuf Oral Solution .

bannner image

Liver

Caution

Take Itratuf Oral Solution with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

bannner image

Kidney

Caution

Take Itratuf Oral Solution with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

bannner image

Children

Unsafe

Itratuf Oral Solution is not recommended for children below 12 years as the safety and effectiveness were not established.

Have a query?

FAQs

Itratuf Oral Solution is used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. It works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby killing fungi and clearing the fungal infection.

You are not recommended to take Itratuf Oral Solution with simvastatin as co-administration of these two medicines may cause muscle weakness, unexplained muscle pain or tenderness, dark coloured urine, fever or flu symptoms. However, please consult a doctor before using Itratuf Oral Solution with other medicines.

No, Itratuf Oral Solution is not recommended for use during pregnancy as it may cause harm to the fetus. Also, it is advised to use effective contraceptive measures while taking Itratuf Oral Solution and after 2 months of stopping treatment with Itratuf Oral Solution . However, please inform your doctor if you are pregnant, planning for pregnancy or breastfeeding before taking Itratuf Oral Solution .

Itratuf Oral Solution may cause temporary or permanent hearing loss in some people. It is not necessary for everyone taking Itratuf Oral Solution to experience this adverse effect. However, if you notice any changes in hearing, stop taking Itratuf Oral Solution and consult a doctor immediately.

You are advised to take antacids (drugs used to reduce acid in the stomach) such as omeprazole, pantoprazole and esomeprazole at least 1 hour before or 2 hours after taking Itratuf Oral Solution as co-administration of these medicines at the same time may reduce the effectiveness of Itratuf Oral Solution because antacids decrease the absorption and blood levels of Itratuf Oral Solution . However, please consult a doctor before taking other medicines with Itratuf Oral Solution .

Yes, fungal infection is a contagious skin condition which spreads from one person to another through direct skin to skin contact or by contact with contaminated soil or surfaces and infected animals. Therefore, it is recommended to avoid close direct contact until the infection is clear and avoid sharing things with the infected person as it can also spread the infection.

You are not recommended to stop taking Itratuf Oral Solution without consulting your doctor as it may cause recurring infection. Therefore, take Itratuf Oral Solution for as long as your doctor has prescribed it, and if you experience any difficulty while taking Itratuf Oral Solution , please consult your doctor.

Inform your doctor if you are sexually active and discuss effective contraception methods. Itratuf Oral Solution may reduce the effectiveness of oral contraceptive pills. Thus, you are advised to use barrier methods of contraception like condoms, if you are taking Itratuf Oral Solution .

Inform the doctor about your detailed medical and surgical history, if you have liver, kidney or heart disease or fits and if you are pregnant, breastfeeding or planning pregnancy. Inform your doctor if you are taking any other medicines including supplements or herbal products as Itratuf Oral Solution may interact with other medicines. Also, let your doctor know if you are stopping any medicine.

Itratuf Oral Solution contains Itraconazole, an antifungal that works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, it causes the main components of fungal cells to leak out, kill fungi, and clear the fungal infection.

Yes, you should swallow the capsule whole with a glass of water. Do not crush, chew or break it.

The side effects of Itratuf Oral Solution include nausea, headache, diarrhoea, stomach pain, fatigue (overtiredness), back pain, cough, and sore throat. If these side effects persist or worsen, please consult your doctor.

If you have taken overdose of Itratuf Oral Solution , please consult your doctor immediately.

Store Itratuf Oral Solution at room temperature. Protect from light and moisture. Keep out of reach and sight of children.

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - ITR0162

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

May 2, 2025 | 1:20 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/022484s000lbl.pdf
  2. https://mims.com/malaysia/drug/info/itraconazole/patientmedicine/itraconazole%2B-%2Boral
  3. https://www.drugs.com/mtm/itraconazole.html
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