apollo
logo
0

Welcome User

Login/Sign Up

Home
Buy Medicines
Lab Tests
Doctor Consult
Circle Membership
insurance
Blogs
Contact Us
Privacy Policy
Return & Refunds
Need Help
Terms and Conditions
Select Delivery Location
compositionComposition:INCLISIRAN-284MG
prescriptionPrescription Medicine
Izirize PFS 284 mg Injection 1.5 ml
Izirize PFS 284 mg Injection 1.5 ml

Izirize PFS 284 mg Injection 1.5 ml is used as part of a comprehensive treatment plan, which includes a balanced diet and other medications, to help control cholesterol levels. It lowers LDL cholesterol (LDL-C) in adults with heterozygous familial hypercholesterolemia (HeFH) or clinical atherosclerotic cardiovascular disease (ASCVD) who need further reduction of LDL-C. Some individuals may experience side effects such as headache, dizziness, cough, injection site reactions, and diarrhoea. Let the doctor know if you are pregnant, breastfeeding, taking other medicines or have pre-existing medical conditions.

Read more
Written By ,
Reviewed By Santoshini Reddy G , M Pharmacy
OffersOffers & Discounts

Get Free delivery (₹99) with circle icon

Join Circle
coupon
Get 18% Off with Coupons
coupon
coupon
coupon
Extra 10% Off with Bank Offers

More about the Product

Composition :

INCLISIRAN-284MG

Manufacturer/Marketer :

J B Chemicals & Pharmaceuticals Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Izirize PFS 284 mg Injection 1.5 ml

Izirize PFS 284 mg Injection 1.5 ml is used to lower low-density lipoprotein cholesterol (LDL-C), commonly known as bad cholesterol, in patients with hyperlipidemia. Hyperlipidemia is a condition marked by elevated levels of lipids (fats), such as cholesterol and triglycerides, in the blood, which can increase the risk of heart disease, stroke, and other health complications.

Izirize PFS 284 mg Injection 1.5 ml contains Inclisiran, a PCSK9 inhibitor monoclonal antibody. It works by blocking PCSK9, a protein that regulates receptors on liver cells responsible for clearing LDL-C from the bloodstream. Inhibiting PCSK9 increases the number of LDL receptors, which lowers LDL-C levels and reduces the risk of atherosclerotic cardiovascular diseases.

A healthcare professional will administer Izirize PFS 284 mg Injection 1.5 ml. In some cases, this medicine may cause side effects like headache, dizziness, cough, bronchitis, diarrhoea, back pain, pain in a joint, or injection site reactions. The majority of these side effects may not require medical treatment and will subside with time. However, if the side effects persist or worsen, consult a doctor.

Izirize PFS 284 mg Injection 1.5 ml should not be administered if you are allergic to it. Before receiving the injection, inform your doctor about any allergies, medications, or conditions that may affect your treatment, such as a history of heart, liver, or kidney disorder. Pregnant and breastfeeding women should consult their doctor before receiving Izirize PFS 284 mg Injection 1.5 ml. Izirize PFS 284 mg Injection 1.5 ml is not recommended for children below 18 years, as its safety and efficacy have not been established.

Uses of Izirize PFS 284 mg Injection 1.5 ml

Treatment of familial heterozygous hypercholesterolemia (HeFH):Izirize PFS 284 mg Injection 1.5 ml is used to treat heterozygous familial hypercholesterolemia (HeFH) in people who require extra LDL cholesterol reduction. It can be administered alone or in combination with other medications (e.g. statins).
  • Treatment of atherosclerotic cardiovascular disease (ASCVD):Izirize PFS 284 mg Injection 1.5 ml lowers the levels of low-density lipoprotein (LDL) cholesterol in individuals with clinical ASCVD. This helps reduce the risk of other cardiovascular issues by preventing cholesterol from blocking blood flow in the arteries.

    • Have a query?

    Directions for Use

    • Follow your doctor's instructions on the dosage and timing of this medication.
    • Izirize PFS 284 mg Injection 1.5 ml is administered by the doctor or nurse in a healthcare setting.
    • Do not self-administer.

    Key Benefits

    Izirize PFS 284 mg Injection 1.5 ml effectively reduces LDL cholesterol (LDL-C) in adults with heterozygous familial hypercholesterolemia (HeFH) or clinical atherosclerotic cardiovascular disease (ASCVD). Lowering LDL cholesterol helps prevent cholesterol buildup on the arterial walls, thereby reducing the risk of blockages that can restrict blood flow to the heart, brain, and other vital organs. It has minimal interactions with most other cholesterol-lowering medications, making it suitable for use in combination with other treatments.

    How Izirize PFS 284 mg Injection 1.5 ml Works

    Izirize PFS 284 mg Injection 1.5 ml contains Inclisiran, a PCSK9 inhibitor monoclonal antibody. It works by blocking PCSK9, a protein that regulates receptors on liver cells responsible for clearing LDL-C from the bloodstream. Inhibiting PCSK9 increases the number of LDL-C receptors, which lowers LDL-C levels and reduces the risk of atherosclerotic cardiovascular diseases.

    Storage

    Store in a cool and dry place away from sunlight
    Side effects of Izirize PFS 284 mg Injection 1.5 ml
    • Injection site reaction can include numbness or redness.
    • Get a physical examination, follow your doctor's instructions, if it worsens or gets swollen.
    • Apply cold compress for pain relief.
    • Practice good hygiene and keep the injection site away from heat and pressure.
    Here are the steps to manage Joint Pain caused by medication usage:
    • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
    • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
    • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
    • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
    • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
    • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
    Managing Medication-Triggered Bronchitis (Inflammation of the bronchial tubes): A Step-by-Step Guide:
    • If you experience symptoms like coughing, wheezing, chest tightness, or difficulty breathing after taking medication, seek medical attention immediately.
    • Your healthcare provider will work with you to stop the medication causing the reaction, start alternative treatments, and provide supportive therapy.
    • To manage symptoms and prevent complications, follow your doctor's advice to use inhalers or nebulizers as prescribed, practice good hygiene, avoid irritants, stay hydrated, and get plenty of rest.
    • Regularly track your symptoms and report any changes or concerns to your healthcare provider.

    What if I have taken an overdose of Izirize PFS 284 mg Injection 1.5 ml

    Izirize PFS 284 mg Injection 1.5 ml is administered in a controlled medical setting by a healthcare professional, and the likelihood of an overdose is much less. However, if you suspect an overdose or experience any adverse effects, seek medical attention immediately.

    Drug Warnings

    Inform your doctor if you are allergic to any of the components in Izirize PFS 284 mg Injection 1.5 ml. If you are pregnant or breastfeeding, consult your doctor before receiving Izirize PFS 284 mg Injection 1.5 ml. Let your doctor know if you have a history of heart disease, kidney or liver disease, allergic reactions, breathing problems, arthritis, psoriasis, eczema, urinary tract infections or if you have had any recent vaccinations. Izirize PFS 284 mg Injection 1.5 ml is not recommended for children below 18 years, as its safety and efficacy have not been established.

    Drug-Drug Interactions

    verifiedApollotooltip
    No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

    Drug-Drug Interactions

    Login/Sign Up

    Drug-Food Interactions

    verifiedApollotooltip
    No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

    Drug-Food Interactions

    Login/Sign Up

    Diet & Lifestyle Advise

    • To improve heart health, include omega-3-rich foods like salmon, mackerel, and sardines in your diet.
    • Limit dietary cholesterol from eggs, shellfish, and fatty meats.
    • Limit alcohol to moderate levels to avoid increasing cholesterol.
    • Relaxation techniques such as meditation and yoga might help you manage your stress.
    • Minimize processed and refined carbohydrates like white bread and sugary snacks.
    • Exercise for at least 30 minutes most days to raise HDL and lower LDL cholesterol.
    • Maintain a healthy weight to help lower LDL levels.
    • Quit smoking to improve HDL cholesterol and overall heart health.

    Habit Forming

    No

    Therapeutic Class

    [ANTILIPEMICS]

    All Substitutes & Brand Comparisons

    bannner image

    Alcohol

    Caution

    It is unknown if alcohol interacts with Izirize PFS 284 mg Injection 1.5 ml. Please consult a doctor if you have any concerns.

    bannner image

    Pregnancy

    Caution

    Please consult a doctor if you are pregnant or planning for pregnancy. Your doctor will prescribe only if the benefits outweigh the risks.

    bannner image

    Breast Feeding

    Caution

    There is limited data on the use of Izirize PFS 284 mg Injection 1.5 ml during breastfeeding. Consult your healthcare provider to assess risks and benefits.

    bannner image

    Driving

    Caution

    Izirize PFS 284 mg Injection 1.5 ml is unlikely to impair your ability to drive or operate machinery. However, sometimes, Izirize PFS 284 mg Injection 1.5 ml makes you feel tired and dizzy; if it happens to you, do not drive or operate machinery.

    bannner image

    Liver

    Caution

    Inform your doctor if you have liver impairment. Your doctor will weigh the benefits and any potential risks before prescribing Izirize PFS 284 mg Injection 1.5 ml.

    bannner image

    Kidney

    Caution

    Inform your doctor if you have kidney impairment. Your doctor will weigh the benefits and any potential risks before prescribing Izirize PFS 284 mg Injection 1.5 ml.

    bannner image

    Children

    Caution

    Izirize PFS 284 mg Injection 1.5 ml is not recommended for children below 18 years, as its safety and efficacy have not been established.

    bannner image

    Heart

    Caution

    Inform your doctor if you have heart disease before using Izirize PFS 284 mg Injection 1.5 ml. Your doctor will prescribe only if the benefits outweigh the risks.

    bannner image

    Geriatrics

    Consult your doctor

    Izirize PFS 284 mg Injection 1.5 ml can be used in the elderly when prescribed by a doctor. If you have any concerns about using Izirize PFS 284 mg Injection 1.5 ml, please consult a doctor.

    FAQs

    Izirize PFS 284 mg Injection 1.5 ml is used to reduce low-density lipoprotein cholesterol (LDL-C) in adults with heterozygous familial hypercholesterolemia (HeFH) or clinical atherosclerotic cardiovascular disease (ASCVD) who need further reduction of LDL-C.

    Izirize PFS 284 mg Injection 1.5 ml contains Inclisiran, a PCSK9 inhibitor monoclonal antibody. It works by lowering the amount of LDL cholesterol in the blood, decreasing the amount of cholesterol that may build up on the walls of the arteries and block blood flow to the heart, brain, and other parts of the body.

    Izirize PFS 284 mg Injection 1.5 ml is usually given as an initial dose, followed by a second dose after 3 months, and then administered every 6 months thereafter.

    If a dose is missed by less than 3 months, the doctor will administer Izirize PFS 284 mg Injection 1.5 ml and continue the original dosing schedule. If more than 3 months are missed, a new schedule will be started with an initial dose, another dose at 3 months, and then every 6 months.

    No dose adjustment is required for elderly patients, but caution is advised when administering Izirize PFS 284 mg Injection 1.5 ml to individuals with severe renal disease, as they may be at a higher risk for complications. Close monitoring is important during treatment.

    Some people may experience reactions at the injection site, such as pain, redness, or swelling, but these typically resolve on their own. Seek medical advice if the reactions persist.

    PCSK9 is a protein that regulates the number of LDL receptors on cells. These receptors help control cholesterol levels by binding to LDL particles, which carry cholesterol in the blood. Most of these receptors are in the liver, where they remove excess cholesterol from the body.

    Pregnant or breastfeeding women should consult their healthcare provider before using Izirize PFS 284 mg Injection 1.5 ml, as its safety during pregnancy and breastfeeding is not fully established.

    The side effects of Izirize PFS 284 mg Injection 1.5 ml may include headache, dizziness, cough, bronchitis, diarrhoea, back pain, or pain in a joint. Seek medical care if the side effects persist or worsen.

    Izirize PFS 284 mg Injection 1.5 ml may increase the risk of urinary tract infections. Consult the doctor if you experience symptoms of urinary tract infection like frequent urination, pain/burning sensation during urination, pelvic/rectal pain, discoloured urine or smelly urine.

    Country of origin

    India

    Manufacturer/Marketer address

    Cnergy It Park, Unit A2, 3rd Floor & Unit A, 8Th Floor, Appa Saheb Marathe Marg, Prabhadevi, Mumbai 400025
    Other Info - IZI0014

    Disclaimer

    While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
    whatsapp Floating Button
    Buy Now
    Add to Cart