Jakbic XR Tablet 14's
MRP ₹420
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About Jakbic XR Tablet 14's
Jakbic XR Tablet 14's is used to treat rheumatoid arthritis (an autoimmune disease which leads to joint pain and damage), psoriatic arthritis (an inflammatory condition of the joints), and ulcerative colitis (an inflammatory disease of the large intestine).
Jakbic XR Tablet 14's contains Tofacitinib, which works by blocking the Janus kinase enzyme, thereby lowering inflammation and symptoms associated with rheumatoid and psoriatic arthritis.
Not everyone who is taking Jakbic XR Tablet 14's will get these side effects. In some cases, you may experience common side effects such as diarrhoea, headache, upper respiratory tract infection, cold, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
You can take Jakbic XR Tablet 14's with or without food. It should be swallowed as a whole with a glass of water. Do not chew, bite, crush, or break it. Your doctor will advise you on how often you should take your tablets based on your medical condition. It is always important to complete your treatment course for better results.
Avoid taking Jakbic XR Tablet 14's if you are allergic to it. Inform your doctor if you have an active infection, if you are taking immunosuppressants, medicines that affect the immune system or corticosteroids. Avoid taking Jakbic XR Tablet 14's if you are pregnant or breastfeeding. Jakbic XR Tablet 14's is not recommended for use in children below 18 years as safety and effectiveness have not been established.
Uses of Jakbic XR Tablet 14's
Jakbic XR Tablet 14's is used in the treatment of Rheumatoid arthritis, Psoriatic arthritis, and Ulcerative colitis. The detailed uses of Jakbic XR Tablet 14's are as follows:
- Treatment of Rheumatoid Arthritis: Jakbic XR Tablet 14's helps to manage moderate to severe rheumatoid arthritis by reducing joint pain, inflammation, and slowing disease progression.
- Management of Psoriatic Arthritis: Jakbic XR Tablet 14's treats active psoriatic arthritis by reducing joint pain, swelling, stiffness, and improving overall joint function.
- Treatment of Ulcerative Colitis: Jakbic XR Tablet 14's helps to induce and maintain remission in moderate to severe ulcerative colitis.
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Directions for Use
- Jakbic XR Tablet 14's can be taken with or without food.
- It is recommended to take Jakbic XR Tablet 14's 1-2 times a day, depending on your medical condition, or as prescribed by your doctor.
- Swallow Jakbic XR Tablet 14's as a whole with a glass of water.
- Do not crush, chew, or break it.
Key Benefits
- Jakbic XR Tablet 14's belongs to a group of medicines called Janus kinase inhibitors used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis.
- Jakbic XR Tablet 14's is indicated for patients with moderate to severe rheumatic arthritis, and psoriatic arthritis who have had intolerance or inadequate response to methotrexate or DMARDs (Disease-Modifying Anti-Rheumatic Drugs).
- This medicine helps lower inflammation and symptoms associated with rheumatoid and psoriatic arthritis.
How Jakbic XR Tablet 14's Works
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- Practice good hygiene by washing hands frequently when touching any wounds.
- Apply creams or lotions to the dry skin and moisturize it.
- Wear the proper clothing and footwear when working outside.
- Cover the wounds with bandage and change it daily.
- Avoid baths at swimming pools, lakes and rivers.
- Inform your doctor about the medication you're taking and the UTI symptoms you're experiencing.
- Your doctor may adjust your medication regimen or consider alternative medications or dosages that may reduce the risk of UTIs.
- Drink plenty of water (at least 8-10 glasses a day) to help flush out bacteria. Avoid sugary drinks and caffeine, which can exacerbate UTI symptoms.
- Urinate when you feel the need rather than holding it in. This can help prevent bacterial growth and reduce the risk of UTIs.
- Consider cranberry supplements: Cranberry supplements may help prevent UTIs by preventing bacterial adhesion.
- Monitor UTI symptoms and report any changes to your doctor.
- If antibiotics are prescribed, take them as directed and complete the full course.
- Drink a lot of water to control diarrhoea and prevent dehydration.
- Avoid spicy, fatty, or high-fiber foods that may irritate the colon.
- Reduce stress through methods such as deep breathing or meditation.
- Include probiotics or supplements containing live bacteria to maintain the health of the gut.
- Quit smoking since smoking makes colitis symptoms worse.
- See your doctor right away if you experience extreme inflammation, bleeding stools, or abdominal pain.
- Inform your doctor about the common cold symptoms you're experiencing due to medication.
- Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
- Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
- Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
- Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
- To promote overall health, drink plenty of water and consume hydrating foods like watermelon and leafy greens.
- Support gut health with probiotic-rich foods such as yoghurt and sauerkraut.
- Eat antioxidant-rich foods like berries and green tea, while limiting sugary drinks, alcohol, and processed foods.
- Additionally, reduce stress through relaxation techniques like deep breathing and meditation.
- Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
- Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
- Protect your skin from extreme heat and try to apply wet compresses.
- Soak in the cool bath, which gives a soothing impact to the affected area.
What if I have taken an overdose of Jakbic XR Tablet 14's
Drug Warnings
- Do not take Jakbic XR Tablet 14's if you are allergic to any of its components; if you have a severe infection, bloodstream infection, or if you have severe liver problems such as cirrhosis.
- Inform your doctor if you have an infection, symptoms of infection, a condition that increases chances of infection, are taking any medicines that affect the immune system; have or had a history of tuberculosis, chronic lung disease, liver problems, hepatitis B/C, cancer, inflammation/ulcers of the large intestine, or kidney problems; are planning to get vaccinated; or have heart problems, high cholesterol, high blood pressure, heart attack, diabetes, or blood clotting problems.
- If your white blood cell count or red blood cell count is low, avoid taking Jakbic XR Tablet 14's.
- Inform your doctor if you notice painful blisters on the skin or if you experience breathing difficulties. Inform your doctor about your complete medical and medication history before starting treatment with Jakbic XR Tablet 14's, which helps the physician decide the best treatment plan.
Drug-Drug Interactions
Drug-Drug Interactions
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Taking Ifosfamide with Jakbic XR Tablet may increase the risk of serious infection.
How to manage the interaction:
Taking Jakbic XR Tablet with Ifosfamide together can possibly result in an interaction, but it can be taken if your doctor has advised it. It is important to keep a close eye on your condition. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
Taking Jakbic XR Tablet with Vincristine may increase the risk of infection.
How to manage the interaction:
Co-administration of Vincristine with Jakbic XR Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
The use of Jakbic XR Tablet with azathioprine may raise the risk of severe infections.
How to manage the interaction:
Co-administration of Azathioprine with Jakbic XR Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
When Jakbic XR Tablet is taken with Vinblastine it may increase the risk of infection.
How to manage the interaction:
There may be a possibility of interaction between Vinblastine and Jakbic XR Tablet, but it can be taken if prescribed by a doctor. It is important to keep a close eye on your symptoms. If you notice any of the following - fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, or pain while urinating - make sure to contact your doctor right away. They will be able to help you and provide the necessary care. Do not discontinue any medications without first consulting your doctor.
Using Jakbic XR Tablet together with cabazitaxel may increase the risk of serious infections.
How to manage the interaction:
Taking Cabazitaxel with Jakbic XR Tablet together can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.
Taking Ibrutinib with Jakbic XR Tablet may increase the risk of infection.
How to manage the interaction:
Although taking Jakbic XR Tablet and Ibrutinib together can cause an interaction, it can be taken if a doctor has suggested it. However, consult a doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting a doctor.
Taking Ceritinib with Jakbic XR Tablet may increase the risk of side effects.
How to manage the interaction:
Although there is a possible interaction between Ceritinib and Jakbic XR Tablet, you can take these medicines together if prescribed by your doctor. If you notice any symptoms like feeling tired, dizzy, or faint, or if you have a fever, diarrhea, or difficulty breathing, it is important to contact a doctor. Do not discontinue any medications without consulting a doctor.
Taking Jakbic XR Tablet with Cladribine may increase the risk of developing serious infections.
How to manage the interaction:
Although taking Cladribine and Jakbic XR Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
Co-administration of Deflazacort with Jakbic XR Tablet may increase the risk of serious infections.
How to manage the interaction:
Although there is a possible interaction between Deflazacort and Jakbic XR Tablet, you can take these medicines together if prescribed by your doctor. If you have any of the symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you urinate, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Taking Jakbic XR Tablet with Topotecan may increase the risk of infection.
How to manage the interaction:
Although there is a possible interaction between Jakbic XR Tablet and Topotecan, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
Drug-Food Interactions
Drug-Food Interactions
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Grapefruit, Grapefruit Juice
How to manage the interaction:
Consuming grapefruit products while taking Jakbic XR Tablet can increase the risk of side effects. Avoid consuming grapefruit products while being treated with Jakbic XR Tablet, as it can lead to an interaction.
Diet & Lifestyle Advise
- Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
- Performing yoga may also help in improving joint flexibility and pain management.
- Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
- Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
- De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
- Acupuncture, massage and physical therapy may also be helpful.
- Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
- Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
- Avoid smoking and alcohol consumption.
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Alcohol
Safe if prescribed
It is not known if alcohol interacts with Jakbic XR Tablet 14's, so please consult a doctor.
Pregnancy
Consult your doctor
Jakbic XR Tablet 14's must not be taken during pregnancy. If you are a woman of child-bearing potential, use effective contraception during the treatment with Jakbic XR Tablet 14's and for 4 weeks after discontinuation.
Breast Feeding
Consult your doctor
Avoid breastfeeding while taking Jakbic XR Tablet 14's. Please consult a doctor if you have any concerns.
Driving
Safe if prescribed
Jakbic XR Tablet 14's generally does not affect your ability to drive. However, drive or operate machinery only if you are alert.
Liver
Consult your doctor
Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this. Jakbic XR Tablet 14's is not recommended for patients with severe liver problems.
Kidney
Consult your doctor
Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Children
Safe if prescribed
Jakbic XR Tablet 14's is not recommended for children below 18 years as safety and effectiveness were not established.
Heart
No serious side effects were observed. But it requires careful consideration and monitoring due to increased risks of heart-related problems, particularly in patients with existing cardiovascular risk factors.
Geriatrics
Consult your doctor
No serious adverse effects were observed; however, it requires careful consideration and caution due to the increased risk of certain adverse events, particularly infections.
FAQs
Jakbic XR Tablet 14's is used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis.
Jakbic XR Tablet 14's works by blocking Janus kinase enzyme, thereby lowers inflammation and symptoms associated with rheumatoid and psoriatic arthritis.
Hypertension/high blood pressure could be a side-effect of Jakbic XR Tablet 14's. Consult your doctor before taking Jakbic XR Tablet 14's if you have high blood pressure or if you are taking anti-hypertensive medicines.
Diarrhoea might be a side-effect of Jakbic XR Tablet 14's. Eat non-spicy meals and drink plenty of fluids to prevent dehydration if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Jakbic XR Tablet 14's might impair fertility in females of reproductive potential. It is not known if the effect is reversible. Therefore, talk to a doctor before starting Jakbic XR Tablet 14's if you are trying to become pregnant or if you have any concerns regarding this.
Jakbic XR Tablet 14's affects the immune system and might lower the ability of the immune system to fight infections. Inform your doctor if you have an active infection, if you have a condition that increases the chance of having infections, if you are taking immunosuppressants, medicines that affect the immune system or corticosteroids.
Jakbic XR Tablet 14's is not recommended for patients with severe liver impairment. Dose adjustment may be needed in patients with mild to moderate liver impairment. Please consult the doctor if you have liver problems.
Jakbic XR Tablet 14's may increase the risk of cancer by changing the way the immune system works. Inform the doctor if you ever had any type of cancer.
Jakbic XR Tablet 14's may begin working within 2-8 weeks after starting the treatment.
Jakbic XR Tablet 14's should not be taken along with tocilizumab as it might increase the risk of infections. Before starting Jakbic XR Tablet 14's, inform the doctor if you are taking tocilizumab.
Prior to starting Jakbic XR Tablet 14's, active or latent tuberculosis test, CBC (complete blood count), LFT (liver function test), and lipid profile tests should be done.
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