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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Justoza GM 1 Tablet 10's is an antidiabetic medicine used to treat Type II Diabetes. It contains Dapagliflozin (sodium-glucose cotransporter-2 inhibitors), Metformin (biguanides), and Glimepiride (sulfonylurea), which work by increasing the amounts of certain natural substances that lower blood sugar when it is high. Common side effects of this medication include vomiting, nausea, abdominal pain, headache, and allergic reactions.

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Manufacturer/Marketer :

Mankind Pharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Justoza GM 1 Tablet 10's

Justoza GM 1 Tablet 10's is an antidiabetic medicine used to treat diabetes. It is used for the treatment of Type II Diabetes. Type II Diabetes Mellitus is a chronic condition that influences the body's metabolism of glucose or blood sugar. Insulin resistance or insufficient insulin production are the two main causes of type 2 diabetes.

Justoza GM 1 Tablet 10's contains Dapagliflozin (sodium-glucose cotransporter-2 inhibitors), Metformin (biguanides), and Glimepiride (sulfonylurea), which work by increasing the amounts of certain natural substances that lower blood sugar when it is high.

Justoza GM 1 Tablet 10's may cause certain side effects, such as vomiting, nausea, abdominal pain, headache, and allergic reactions. If these side effects persist or worsen, please consult your doctor. Justoza GM 1 Tablet 10's should be taken as prescribed by your doctor. 

Justoza GM 1 Tablet 10's should be avoided if you are allergic to any of the medicines or their components. Inform your doctor about your medical history and the medicines you are taking, including herbs and supplements, before starting the treatment with Justoza GM 1 Tablet 10's. This can help prevent unwanted effects. Let your doctor know if you are pregnant or breastfeeding before taking Justoza GM 1 Tablet 10's. It is not recommended for use in children below 18 years of age.

Uses of Justoza GM 1 Tablet 10's

Justoza GM 1 Tablet 10's is used in the treatment of Type II Diabetes Mellitus. The detailed uses of Justoza GM 1 Tablet 10's are as follows:<br/>• Type 2 diabetes management: Justoza GM 1 Tablet 10's helps control high blood sugar levels in adults when lifestyle changes and dual therapy are not sufficient.<br/>• Improved glycemic control: Justoza GM 1 Tablet 10's regulates blood glucose through several complementary actions, including enhancing insulin secretion, improving how the body responds to insulin, and increasing the elimination of excess glucose through urine.<br/>• Reduction of HbA1c levels: Justoza GM 1 Tablet 10's aims to lower glycated hemoglobin (HbA1c), which reflects long-term blood sugar control.<br/>• Prevention of complications: Justoza GM 1 Tablet 10's helps reduce the risk of diabetes-related complications such as kidney damage, nerve issues, and heart disease.<br/>

Directions for Use

• Take Justoza GM 1 Tablet 10's with food to reduce stomach upset or gastrointestinal side effects.• Recommended to take it once daily in the morning or as advised by your doctor.• Swallow the medicine as a whole with glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Justoza GM 1 Tablet 10's is a combination of three drugs, namely: Dapagliflozin, Metformin and Glimepiride. Justoza GM 1 Tablet 10's belongs to the group of anti-diabetic medicines used to treat type-2 diabetes mellitus. Dapagliflozin helps remove excess sugar from the body via urine. Metformin helps reduce the sugar production by cells in the liver and delays sugar absorption from the intestines. Glimepiride works by stimulating beta cells in the pancreas that produce insulin. Thus, insulin helps to remove sugar from the blood.

How Justoza GM 1 Tablet 10's Works

Justoza GM 1 Tablet 10's contains Dapagliflozin (sodium-glucose cotransporter-2 inhibitors), Metformin (biguanides), and Glimepiride (sulfonylurea), which work by increasing the amounts of certain natural substances that lower blood sugar when it is high.

Storage

• Store in a cool and dry place away from sunlight.• Keep Justoza GM 1 Tablet 10's out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Justoza GM 1 Tablet
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
  • Get plenty of rest and sleep.
  • Keep your body warm.
  • Drink plenty of fluids to stay hydrated.
  • Avoid strenuous activities.
  • Maintain good hygiene to prevent flu from spreading.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

What if I have taken an overdose of Justoza GM 1 Tablet 10's

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Justoza GM 1 Tablet 10's may include low blood sugar, stomach pain and diarrhoea. Seek immediate medical attention if you observe these symptoms or think you might have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Justoza GM 1 Tablet 10's should be avoided if you are allergic to any of the medicines or their components. Before starting the treatment, inform your doctor about your medical history and the medications you take, including herbs and supplements, to rule out any side effects. It is unknown whether Justoza GM 1 Tablet 10's can be given to pregnant women or breastfeeding mothers. Hence, inform your doctor if you are pregnant or breastfeeding. It is not recommended for use in children below 18 years of age. Avoid drinking alcohol while on Justoza GM 1 Tablet 10's as it increases the risk of hypoglycemia and lactic acidosis (when the lactic acid increases in the body, which impacts the functioning of various organs in the body). Inform your doctor if you have any liver/kidney disease, heart problems, and hypertension before taking Justoza GM 1 Tablet 10's.

Drug-Drug Interactions

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MetforminIopamidol
Critical

Drug-Drug Interactions

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How does the drug interact with Justoza GM 1 Tablet:
Co-administration of Justoza GM 1 Tablet with Gatifloxacin may sometimes affect blood glucose levels. Both low blood glucose and, less frequently, high blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Gatifloxacin can be taken with Justoza GM 1 Tablet if prescribed by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremor, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue the medication without consulting a doctor.
MetforminIopamidol
Critical
How does the drug interact with Justoza GM 1 Tablet:
Co-administration of Iopamidol with Justoza GM 1 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Justoza GM 1 Tablet with Iopamidol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIocetamic acid
Critical
How does the drug interact with Justoza GM 1 Tablet:
Co-administration of Justoza GM 1 Tablet and Iocetamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Justoza GM 1 Tablet with Iocetamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIoxitalamic acid
Critical
How does the drug interact with Justoza GM 1 Tablet:
Co-administration of Justoza GM 1 Tablet and Ioxitalamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Justoza GM 1 Tablet with Ioxitalamic acid is not recommended, please consult your doctor before taking it.
MetforminIotroxic acid
Critical
How does the drug interact with Justoza GM 1 Tablet:
Co-administration of Iotroxic acid with Justoza GM 1 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Justoza GM 1 Tablet with Iotroxic acid is not recommended, please consult your doctor before taking it.
MetforminIopanoic acid
Critical
How does the drug interact with Justoza GM 1 Tablet:
Co-administration of Iopanoic acid with Justoza GM 1 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Justoza GM 1 Tablet with Iopanoic acid is not recommended, please consult your doctor before taking it.
MetforminIodamide
Critical
How does the drug interact with Justoza GM 1 Tablet:
Co-administration of Justoza GM 1 Tablet and Iodamide can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Justoza GM 1 Tablet with Iodamide is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIohexol
Critical
How does the drug interact with Justoza GM 1 Tablet:
Co-administration of Iohexol with Justoza GM 1 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Justoza GM 1 Tablet with Iohexol is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminMetrizamide
Critical
How does the drug interact with Justoza GM 1 Tablet:
Co-administration of Justoza GM 1 Tablet with Metrizamide together can cause the risk of lactic acidosis (when the body produces too much lactic acid ).

How to manage the interaction:
Taking Justoza GM 1 Tablet with Metrizamide is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience headaches, muscle cramps or pain, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetforminIoglicic acid
Critical
How does the drug interact with Justoza GM 1 Tablet:
Co-administration of Ioglicic acid with Justoza GM 1 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Justoza GM 1 Tablet with Ioglicic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Try doing 30 minutes of moderate-intensity physical activity or one hour and 15 minutes of high-intensity exercise weekly. 
  • Include your diet with whole grain foods, fruits and veggies and other fiber-enriched foods. 
  • Add omega-3 fatty acid-containing oils for daily cooking.
  • Avoid taking too much stress as it may elevate your blood sugar level. You can adopt stress management techniques like mindfulness, meditation, or yoga to control stress-related blood sugar changes.
  • Loss of weight gradually to achieve a healthy body mass index (18.5 to 24.9).
  • Keep your blood pressure as normal (140/90) as possible, as it reduces the risk of cardiovascular diseases in diabetes patients.
  • Avoid smoking and alcohol consumption while on treatment with Justoza GM 1 Tablet 10's.
  • Take short, frequent meals, and avoid prolonged fasting when taking Justoza GM 1 Tablet 10's.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS
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Alcohol

Unsafe

Alcohol increases the impact of metformin on lactate metabolism. Hence, you should not consume excessive amounts of alcohol, either temporarily or permanently, while taking Justoza GM 1 Tablet 10's.

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Pregnancy

Caution

There are no adequate studies on the effect of Justoza GM 1 Tablet 10's in pregnancy. If you are pregnant or planning pregnancy, inform your doctor before taking Justoza GM 1 Tablet 10's.

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Breast Feeding

Caution

Justoza GM 1 Tablet 10's is generally not recommended in breastfeeding. Hence, if you are breastfeeding, inform your doctor before using Justoza GM 1 Tablet 10's.

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Driving

Caution

Justoza GM 1 Tablet 10's usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Justoza GM 1 Tablet 10's may cause lactic acidosis due to metformin accumulation. The risk increases with hepatic insufficiency. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

Renal impairment also increases the risk of lactic acidosis. Hence, Justoza GM 1 Tablet 10's should be used cautiously if you have kidney problems. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Justoza GM 1 Tablet 10's is not recommended for children below 18 years as the safety and effectiveness were not established.

Have a query?

FAQs

Justoza GM 1 Tablet 10's is used for the treatment of Type II Diabetes.

Justoza GM 1 Tablet 10's contains Dapagliflozin, Metformin, and Glimepiride, which work by increasing the amounts of certain natural substances that lower blood sugar when it is high.

Please consult your doctor if you have concerns and for more information on this.

If you forget to take Justoza GM 1 Tablet 10's, take it as soon as you remember. However, if it is time for the next dose, avoid taking it and do not double dose to make up for the missed dose. Taking an overdose might cause your sugar level to fall down rapidly.

Country of origin

India

Manufacturer/Marketer address

208, Okhla Industrial Estate, Phase Iii, New Delhi - 110020.
Other Info - JUS0117

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