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compositionComposition:KANAMYCIN-500MG
prescription
Prescription Medicine
info
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Kanamac 0.5 gm Injection is used to treat severe bacterial infections and multi-drug-resistant tuberculosis. It contains Kanamycin which works by preventing the synthesis of infection-causing bacteria. In some cases, this medicine may cause side effects such as dizziness, loss of balance, pain at the injection site, and rash. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

KANAMYCIN-500MG

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Kanamac 0.5 gm Injection

Kanamac 0.5 gm Injection is an injectable antibiotic designed to treat serious and life-threatening bacterial infections throughout the body. It is typically prescribed when other standard antibiotics are not effective or cannot be used. This medication helps eliminate harmful bacteria, allowing your body to recover from severe illness.

Because this medicine is given as an injection, its absorption is not affected by food, meaning you do not need to worry about eating before your dose. It must be administered at regular, evenly spaced times to keep a constant level of the medicine in your body. Drinking extra water and staying well-hydrated during your treatment can also help support your kidneys while you receive this therapy.

While undergoing treatment, you may experience mild side effects like irritation at the injection site, nausea, or a mild headache. However, you must contact your doctor immediately if you experience serious side effects such as ringing in your ears, hearing changes, severe dizziness, or a sudden decrease in how much you urinate. Seeking prompt medical attention for these symptoms is essential to prevent permanent damage.

Before you start taking this medicine, talk to your doctor if you have a history of kidney disease, hearing problems, or nerve disorders. Do not take this if you have had a severe allergic reaction to similar antibiotic injections in the past. Your healthcare provider will assess your medical history to ensure this treatment is safe for you.

This medicine can interact with other drugs that cause kidney or hearing damage, as well as certain water pills and muscle relaxants. It is also important to talk to your doctor or pharmacist if you are pregnant, breastfeeding, or an older adult, as these groups may require specialised monitoring during treatment. Avoid alcohol and smoking during therapy, as they can dehydrate your body and slow down your overall recovery process.

Uses of Kanamac 0.5 gm Injection

Kanamac 0.5 gm Injection is used to treat serious bacterial infections where other antibiotics may not be suitable or effective. Its common uses include:

  • Severe bacterial infections: This injection helps eliminate harmful bacteria causing serious infections in the blood, lungs, abdomen, or urinary tract.
  • Tuberculosis: It is used in combination with other medications to treat active tuberculosis infections when first-line treatments are not suitable.

Key Benefits

This medication provides vital, targeted support to help your body overcome severe, deep-seated bacterial infections. By directly stopping the growth of harmful bacteria, it delivers several key benefits:

  • Promotes faster recovery: By rapidly halting the spread of bacteria, this injection helps reduce severe symptoms, allowing your body to start healing sooner.
  • Clears drug-resistant infections: It offers a dependable treatment option for complex infections that standard oral antibiotics cannot successfully clear.
  • Protects vital organs: Stopping infections that spread through the bloodstream to multiple parts of the body early helps prevent bacteria from causing further damage to internal organs.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Kanamac 0.5 gm Injection will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Kanamac 0.5 gm Injection Works

Kanamac 0.5 gm Injection is a type of antibiotic known as an aminoglycoside that works by targeting the specific machinery inside bacterial cells responsible for making proteins. These proteins are essential for bacterial growth, multiplication, and maintenance of cellular structure. By binding to these protein-making units, Kanamycin disrupts protein production and causes bacteria to produce faulty proteins, which weakens the bacterial cells and prevents them from reproducing. This allows your body’s natural immune defences to eliminate the remaining bacteria and clear the infection.
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Alcohol

Caution

It is recommended to avoid or limit the alcohol intake while using Kanamac 0.5 gm Injection.

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Pregnancy

Unsafe

Kanamac 0.5 gm Injection is not recommended and is unsafe to use during pregnancy since it affects the baby. Please consult your doctor if you are planning to become pregnant or already pregnant before starting Kanamac 0.5 gm Injection.

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Breast Feeding

Caution

It is not known if Kanamac 0.5 gm Injection affects breastfeeding. Please consult your doctor before taking Kanamac 0.5 gm Injection if you are breastfeeding.

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Driving

Unsafe

Kanamac 0.5 gm Injection may you to feel dizzy that can alter your ability to drive. Drive or operate machinery only when you are mentally alert.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Kanamac 0.5 gm Injection. Dose adjustment may be required.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before taking Kanamac 0.5 gm Injection. Dose adjustments may be required. Regular kidney function monitoring is advised in patients with severe kidney diseases.

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Children

Caution

Kanamac 0.5 gm Injection should be used in children only when prescribed by a doctor.

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Heart

Caution

Kanamac 0.5 gm Injection should be administered with caution in patients with heart problems. Therefore, please talk to your doctor before receiving Kanamac 0.5 gm Injection.

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Geriatrics

Caution

Kanamac 0.5 gm Injection should be administered with caution in older adults. Always seek medical advice before receiving it.

What if I have taken an overdose of Kanamac 0.5 gm Injection

Because this medication is usually given by a healthcare professional, an overdose is highly unlikely. However, if you suspect an overdose or experience severe symptoms like extreme dizziness, hearing changes, severe muscle weakness, or a sudden drop in urination, seek emergency medical care immediately.

Diet & Lifestyle Advise

  • Increase fluid intake: Drink plenty of water throughout the day, unless advised otherwise by your doctor. Staying well-hydrated is essential to help your kidneys flush out the medicine safely and reduce the risk of kidney damage.
  • Avoid kidney-stressing substances: Do not take over-the-counter pain relievers like ibuprofen, naproxen, or other nonsteroidal anti-inflammatory drugs (NSAIDs) without asking your doctor, as they can put extra strain on your kidneys during treatment.
  • Rest and conserve energy: Give your body ample time to rest. Severe bacterial infections require significant energy for your immune system to fight off.
  • Monitor your hearing and balance: Pay close attention to any subtle changes in your hearing, balance, or any ringing in your ears. Documenting these changes can help you provide clear feedback to your doctor during check-ups.
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How Soon It Starts Working

The time required for Kanamac 0.5 gm Injection to start to work: Kanamac 0.5 gm Injection ideally shows its action within 1 hour after administration. The time for which the effects of Kanamac 0.5 gm Injection last: The duration of action for Kanamac 0.5 gm Injection is clinically unknown.

What if you forget to take Kanamac 0.5 gm Injection

If you receive this medicine at a clinic and miss your appointment, contact your healthcare provider immediately to reschedule. If you are administering this medicine at home and miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled injection, skip the missed dose and return to your regular schedule. Do not inject a double dose to make up for a missed one. Talk to your doctor or pharmacist if you are unsure of what to do.

Storage

• Store Kanamac 0.5 gm Injection vials at controlled room temperature, ideally between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Inspect the vial: Always look closely at the solution before injecting. Do not use the medicine if you notice any discoloration, cloudiness, or floating particles inside the vial.
  • Rotate injection sites: If you are receiving intramuscular injections, make sure to rotate the site with each dose to prevent muscle soreness and tissue damage.
  • Never reuse needles: Always use a fresh, sterile needle and syringe for every injection to prevent infections, and immediately discard them in an approved puncture-proof sharps container.
  • Complete the full course: Finish the entire prescribed course of treatment, even if you start to feel completely better, to make sure the infection is fully cleared and does not return.
  • Attend all monitoring appointments: Keep all scheduled appointments for blood tests, kidney function assessments, and hearing evaluations so your doctor can ensure the medicine is working safely.

Drug-Drug Interactions

verifiedApollotooltip

Inform your doctor if you are taking any of the following medicines, as they may interact.

  • Strong diuretics (like furosemide): May significantly increase the risk of hearing loss and balance problems.
  • Other nephrotoxic drugs (like amphotericin B or cisplatin): May increase the risk of serious kidney damage when used at the same time.
  • Neuromuscular blocking agents (muscle relaxants used during certain medical procedures): May increase the risk of severe muscle weakness and breathing difficulties.
KanamycinPolymyxin b
Severe
KanamycinCidofovir
Severe

Drug-Drug Interactions

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KanamycinPolymyxin b
Severe
How does the drug interact with Kanamac 0.5 gm Injection:
Taking Kanamac 0.5 gm Injection with Polymyxin B can increase the risk and severity of side effects.

How to manage the interaction:
There may be a possibility of interaction between polymyxin B and Kanamac 0.5 gm Injection, but it can be taken if prescribed by a doctor. However, if you experience hearing loss, ringing in the ears, vertigo, difficulty breathing, nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
KanamycinCidofovir
Severe
How does the drug interact with Kanamac 0.5 gm Injection:
Taking Kanamac 0.5 gm Injection with cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Although taking Kanamac 0.5 gm Injection and cidofovir together can possibly cause an interaction, it can be taken if your doctor has suggested it. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
KanamycinColistin
Severe
How does the drug interact with Kanamac 0.5 gm Injection:
Coadministration of Colistin with Kanamac 0.5 gm Injection can increase the level and risk of Colistin side effects.

How to manage the interaction:
Although there is a possible interaction between Colistin and Kanamac 0.5 gm Injection, you can take these medicines together if prescribed by your doctor. However, if you experience shortness of breath, swelling, muscle pain, dizziness, or palpitations call your doctor right away. Do not stop using any medications without a doctor's advice.
KanamycinTenofovir disoproxil
Severe
How does the drug interact with Kanamac 0.5 gm Injection:
Coadministration of Kanamac 0.5 gm Injection and Tenofovir disoproxil can increase the risk of developing kidney problems.

How to manage the interaction:
Taking Kanamac 0.5 gm Injection and Tenofovir disoproxil together can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, increased or decreased urination, sudden weight gain or weight loss, shortness of breath, muscle cramps, dizziness, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
KanamycinHuman immunoglobulin
Severe
How does the drug interact with Kanamac 0.5 gm Injection:
Taking Human immunoglobulin with Kanamac 0.5 gm Injection, may raise the risk of kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Human immunoglobulin and Kanamac 0.5 gm Injection, but it can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
KanamycinDeferasirox
Severe
How does the drug interact with Kanamac 0.5 gm Injection:
Deferasirox may cause kidney problems and combining it with Kanamac 0.5 gm Injection may increase that risk.

How to manage the interaction:
Although taking Kanamac 0.5 gm Injection and Deferasirox together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, or irregular heart rhythm, seek immediate medical attention. Drink plenty of water if you experience diarrhoea or vomiting while taking these medications, as dehydration can potentially affect the kidneys. Do not discontinue any medications without a doctor's advice.
KanamycinMagnesium sulfate
Severe
How does the drug interact with Kanamac 0.5 gm Injection:
Taking Magnesium sulfate with Kanamac 0.5 gm Injection can increase the risk of muscle weakness.

How to manage the interaction:
There may be a possibility of interaction between Magnesium sulfate and Kanamac 0.5 gm Injection, but it can be taken if prescribed by a doctor. However, if you experience symptoms such as muscle weakness and breathing difficulties, make sure to contact a doctor. Do not stop using any medications without talking to a doctor.
KanamycinTorasemide
Severe
How does the drug interact with Kanamac 0.5 gm Injection:
Co-administration of Kanamac 0.5 gm Injection with torasemide can increase the risk of toxicity.

How to manage the interaction:
Although taking Kanamac 0.5 gm Injection and torasemide together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as hearing loss, ringing in the ears, vertigo, and kidney problems, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
KanamycinBotulinum toxin
Severe
How does the drug interact with Kanamac 0.5 gm Injection:
Coadministration of Botulinum toxin with Kanamac 0.5 gm Injection can make it more effective for therapy.

How to manage the interaction:
Although there is an interaction between Botulinum toxin and Kanamac 0.5 gm Injection, it can be taken if prescribed by a doctor. However, contact a doctor immediately if you experience muscle weakness or trouble breathing, swallowing, or speaking. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Kanamac 0.5 gm Injection when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- BACTERIALS]

FAQs

Kanamac 0.5 gm Injection consists of Kanamycin, an antibiotic that prevents the growth of bacteria. Thus, it effectively treats bacterial infections and tuberculosis.
Kanamac 0.5 gm Injection should be used with proper caution and doctor consultation if you have asthma, muscle (myasthenia gravis) problems, nerve problems, liver or kidney diseases, sulphite allergy, and Parkinson's disease. Please inform your doctor in advance if you have any other medical concerns.
Do not stop using Kanamac 0.5 gm Injection even if you feel better until the doctor's advised course is finished.
Kanamac 0.5 gm Injection is usually given for a shorter period of 7-10 days. However, your doctor will decide the dosage and duration based on your medical condition.
While using Kanamac 0.5 gm Injection, if you experience any itching, skin rash, hoarseness (abnormal voice changes), shortness of breath, trouble breathing, trouble swallowing, and swelling of hands, face, or mouth, please stop using the medicine and seek medical advice promptly.
Kanamac 0.5 gm Injection is safe when used as per the dose and duration advised by a doctor.
Kanamac 0.5 gm Injection should be administered by a healthcare professional. The dosage of Kanamac 0.5 gm Injection may vary based on your condition and the severity of the infection. Do not self-administer.
You are not advised to take higher than recommended doses as Kanamac 0.5 gm Injection may increase the risk of serious side effects and toxicity. If your symptoms worsen and are not relieved by the recommended dose, consult your doctor for re-evaluation.
Store Kanamac 0.5 gm Injection in a cool and dry place below 30°C. Protect from light and keep it out of reach of children. Kanamac 0.5 gm Injection should be disposed, by following local guidelines or asking your pharmacist on how to properly dispose of any unused medicine.
Inform your doctor if your symptoms are not relieved after completing the entire course of Kanamac 0.5 gm Injection. If you notice any undesirable effects that bother you while taking Kanamac 0.5 gm Injection, consult your doctor.
Kanamac 0.5 gm Injection causes side effects such as dizziness, loss of balance, pain at the injection site, rash, and hearing loss. However, these side effects do not require any medical attention, as they will gradually reduce over time. Please, contact a doctor if these side effects persist for longer durations.
No, this medicine is not absorbed well by the stomach and digestive tract. It must be given as an injection into a muscle or a vein to treat infections effectively. Talk to your doctor if you have questions about how this medicine is given.
You should contact your healthcare provider immediately. Ringing in your ears (tinnitus) can be an early sign of hearing damage, which may become permanent if ignored. Talk to your doctor.
This medicine is generally not recommended during pregnancy because it can cause hearing loss in the unborn baby. It is typically only used if no other safer treatment is available. Talk to your doctor.
No, you should always complete the entire course of treatment prescribed by your healthcare provider. Stopping early can cause the remaining bacteria to multiply, making the infection return and become harder to treat. Talk to your doctor.
Yes, your doctor will likely schedule regular blood tests to check your kidney function and to monitor the level of medicine in your body. This helps keep the treatment safe and effective. Talk to your doctor.
If you have kidney disease, your doctor will need to adjust your dose carefully or monitor your kidney health very closely, as this medicine can cause further kidney damage. Talk to your doctor.
The length of treatment depends entirely on the type and severity of your infection, as well as how your body responds to the medicine. Talk to your doctor.
No, this medicine is an antibiotic and is only effective against bacterial infections. It will not work to treat viral infections such as the flu or common cold. Talk to your doctor.

Disclaimer

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Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - KAN0001
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