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Written By Thota sri Harshini ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Kefnir Capsule is used to treat bacterial infections in children. It contains Cefdinir, which interferes with bacterial cell wall formation and kills the bacteria. In some cases, this medicine may cause side effects such as diarrhea, nausea, stomach pain, vomiting, rash, and abnormal stools. Before giving this medicine to your child, inform the doctor if the child is taking any other medications or has any pre-existing medical conditions.

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Composition :

CEFDINIR-300MG

Manufacturer/Marketer :

Glenmark Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

About Kefnir Capsule

Kefnir Capsule belongs to a class of medications called antibiotics. It is used to treat bacterial infections of the urinary tract, bones and joints, heart, lungs, brain, chest, ears, skin, and soft tissues. Bacteria infection occurs when harmful bacteria grow in the body and multiply quickly. It can infect any part of the body. It does not work against infections caused by viruses such as flu or the common cold.

Kefnir Capsule contains Cefdinir, a cephalosporin antibiotic that works by interfering with the formation of the bacterial cell wall (a protective covering) necessary for their survival. This damages the bacterial cell wall and kills bacteria.

Kefnir Capsule to be given as prescribed by your doctor. Use it for as long as your doctor has prescribed it for your child based on their medical condition. In some cases, your child may experience diarrhea, nausea, stomach pain, vomiting, rash, and abnormal stools. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Please tell your doctor if your child is allergic to Kefnir Capsule, cephalosporin antibiotics or any other medicines. You are advised to maintain a time gap of a minimum of 2 hours if you are giving this medicine to your child with other medicines like antacids containing aluminium, magnesium, iron supplements, and multivitamins containing iron. It is not recommended for infants under 6 months of age as the safety and efficacy were not established.

Uses of Kefnir Capsule

Kefnir Capsule is used to treat bacterial infections in children. The detailed uses of Kefnir Capsule are as follows:

  • Treatment of Bacterial Infections: Kefnir Capsule is a third-generation cephalosporin antibiotic used to treat various bacterial infections.
  • Respiratory Tract Infections: Kefnir Capsule is effective against pneumonia, bronchitis, and sinusitis, helping clear infections in the lungs and airways.
  • Ear and Throat Infections: Kefnir Capsule is commonly prescribed for middle ear infections (otitis media), strep throat, and tonsillitis.
  • Skin and Soft Tissue Infections: Kefnir Capsule helps treat cellulitis and other bacterial skin infections, preventing the spread of harmful bacteria.

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Directions for Use

  • Kefnir Capsule can be given with or without food.
  • Follow your doctor's instructions regarding the dosage and duration of the medication.
  • Shake well before use. Administer the advised dose to the child using the measuring cup/measuring spoon/dropper.
  • Avoid using regular household spoons, as they may not measure the dose correctly.

Key Benefits

Kefnir Capsule contains Cefdinir, a cephalosporin antibiotic used to treat several bacterial infections. Cefdinir is a broad-spectrum antibiotic that acts against aerobic (grow in the presence of oxygen) and anaerobic (grow in the absence of oxygen) gram-negative and gram-positive bacteria. It interferes with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. Thus, it damages the bacterial cell wall and kills bacteria.

How Kefnir Capsule Works

Kefnir Capsule contains Cefdinir, a cephalosporin antibiotic that works by interfering with the formation of the bacterial cell wall (a protective covering) necessary for their survival. This damages the bacterial cell wall and kills bacteria.

Storage

Store in a cool and dry place away from sunlight
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
  • Your doctor may adjust the dose of your medication, discontinue, or switch to alternative medicines to manage your symptoms.
  • Drink plenty of water and caffeine-free drinks.
  • Eat more fibre by consuming fruits, vegetables, and whole grains.
  • Avoid processed, spicy, or fatty foods.
  • Try not to skip meals, delay eating, or eat too quickly.
  • Regular exercise can help improve digestion and promote better stool movement.

What if I have taken an overdose of Kefnir Capsule

Never give more than the prescribed dose. An overdose of Kefnir Capsule causes nausea, vomiting, stomach pain, diarrhoea, or seizures. Seek immediate medical attention if it happens accidentally and if you experience any unusual symptoms.

Drug Warnings

Please tell your doctor if the child is allergic to Kefnir Capsule, penicillins, cephalosporin antibiotics, or any of its ingredients. If your child has diabetes, kidney or liver problems, a weak immune system or inflammation of the large intestine, inform your doctor before giving this medicine. It is not recommended for babies below six months of age, as the safety and effectiveness were not established.  You are recommended to complete the entire course of Kefnir Capsule as your doctor prescribes for effective results. Kefnir Capsule may interact with specific tests such as glucose (sugar) in urine and Coomb’s test, giving false-positive results. Therefore, please inform your doctor that the child takes it before undergoing any tests. You are advised to maintain a time gap of a minimum of 2 hours between giving Kefnir Capsule and antacids containing aluminium, magnesium, iron supplements and multivitamins containing iron. These may reduce the body's absorption of this medicine.

Drug-Drug Interactions

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CefdinirBCG vaccine
Critical

Drug-Drug Interactions

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CefdinirBCG vaccine
Critical
How does the drug interact with Kefnir Capsule:
Taking Kefnir Capsule with BCG vaccine may reduce the effects of BCG vaccine.

How to manage the interaction:
Taking Kefnir Capsule with BCG vaccine is not recommended, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Kefnir Capsule:
Taking Kefnir Capsule with argatroban may lead to increase in the effects of Argatroban.

How to manage the interaction:
Although taking Kefnir Capsule and Argatroban together can evidently cause an interaction, but it can be taken if prescribed by a doctor. In case you experience any side effects like chest tightness, shortness of breath, swelling of legs, or palpitations, consult a doctor. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Kefnir Capsule:
Taking Kefnir Capsule with dalteparin together may decrease the therapeutic effects of dalteparin.

How to manage the interaction:
Although taking Kefnir Capsule and dalteparin can evidently cause an interaction, it can be taken if your doctor has suggested it. In case you experience aby unusual effects like lightheadedness, dizziness, unusual bruising, bleeding tendencies, blood in stools or urine, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Kefnir Capsule:
Taking fondaparinux and Kefnir Capsule may increase the effects of fondaparinux.

How to manage the interaction:
Although taking Kefnir Capsule and Fondaparinux can evidently cause an interaction, it can be taken if your doctor has suggested it. In case you experience aby unusual effects like lightheadedness, dizziness, unusual bruising, bleeding tendencies, blood in stools or urine, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Kefnir Capsule:
Taking Kefnir Capsule with bivalirudin may increase the effects of bivalirudin.

How to manage the interaction:
Although taking Kefnir Capsule and Argatroban together can evidently cause an interaction, but it can be taken if prescribed by a doctor. In case you experience any side effects like chest tightness, shortness of breath, swelling of legs, or palpitations, consult a doctor. Do not stop using any medications without first talking to your doctor.
CefdinirCholera, live attenuated
Severe
How does the drug interact with Kefnir Capsule:
Taking Kefnir Capsule with Cholera vaccine can reduce the activity of the Cholera vaccine.

How to manage the interaction:
Taking Kefnir Capsule with Cholera, live attenuated together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Kefnir Capsule:
Taking Kefnir Capsule with heparin may enhance the effects of heparin by anticoagulation(preventing blood from clotting).

How to manage the interaction:
Although taking Kefnir Capsule and Heparin can cause an interaction, it can be taken if a doctor has suggested it. In case you experience aby unusual effects like lightheadedness, dizziness, unusual bruising, bleeding tendencies, blood in stools or urine, consult a doctor. Do not stop using any medications without a doctor's advice.
CefdinirLepirudin
Severe
How does the drug interact with Kefnir Capsule:
Taking Kefnir Capsule with lepirudin may reduce the beneficial effects of therapy.

How to manage the interaction:
Although taking Kefnir Capsule and Lepirudin together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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CEFDINIR-300MGVitamin B complex foods, Vitamin B12 rich foods
Moderate

Drug-Food Interactions

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CEFDINIR-300MGVitamin B complex foods, Vitamin B12 rich foods
Moderate
Common Foods to Avoid:
Avocado, Beetroot, Cereals, Cheese, Chicken, Black Beans, Eggs, Clams, Chickpea, Whole Grains, Shellfish, Spinach, Salmon, Red Meat, Oysters, Potatoes, Kidney Beans, Mackerel, Milk, Kale, Tuna, Yogurt, Liver, Low-Fat Milk, Trout, Fortified Breakfast Cereal, Fish, Beef

How to manage the interaction:
Kefnir Capsule and multivitamin with minerals should not be taken orally at the same time. Iron-containing products decreases the effects of Kefnir Capsule. Although there is an interaction between Kefnir Capsule and multivitamins, it can be taken if advised by a doctor. It should be taken two hours either before or after the dosage of the multivitamin with minerals.

Diet & Lifestyle Advise

  • After completing the entire course of Kefnir Capsule, give probiotics under the doctor's guidance to restore any healthy bacteria that may have been killed in the intestines. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea.
  • Giving certain fermented foods like cheese, yogurt, kombucha, sauerkraut, and kimchi to a child can restore the good bacteria in the intestine.
  • Fibre-rich foods can be easily digested by gut bacteria, which helps stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after antibiotics. Whole grains such as brown rice and whole-grain bread should be included in your child's diet.
  • Make sure the child drinks plenty of water or other fluids every day while you are taking Kefnir Capsule.

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

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Alcohol

Safe if prescribed

-

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Pregnancy

Consult your doctor

-

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Breast Feeding

Consult your doctor

-

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Driving

Safe if prescribed

-

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Liver

Consult your doctor

Give Kefnir Capsule with caution under doctor guidance, especially if the child has a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Consult your doctor

Give Kefnir Capsule with caution as advised by the doctor, especially if the child has a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Safe if prescribed

Kefnir Capsule should not be used in infants less than 6 months of age as the safety and efficacy were not established.

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Heart

If your child has any heart disease, please consult a doctor before giving Kefnir Capsule.

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Geriatrics

Consult your doctor

Kefnir Capsule is for paediatric patients only.

FAQs

Kefnir Capsule is used to treat bacterial infections of the urinary tract, blood, bones and joints, heart, lungs, brain, chest, ears, skin or soft tissues.

Kefnir Capsule works by interfering with the formation of the bacterial cell wall (a protective covering) necessary for their survival. This damages the bacterial cell wall and kills bacteria.

Kefnir Capsule may cause diarrhoea in some children as a common side effect. However, if the condition persists, worsens, or notices blood or mucus in stools, avoid giving it and consult a doctor immediately.

Kefnir Capsule may interfere with the urine test (for sugar) and blood test giving false-positive results. Therefore, if your child is about to undergo any laboratory tests, inform your doctor or lab technician that the child is taking Kefnir Capsule.

Kefnir Capsule is not used to treat viral infections. It is an antibiotic that is used to treat only bacterial infections.

Kefnir Capsule is not recommended for babies below six months of age as the safety and effectiveness are not established.

Do not exceed the recommended dose of Kefnir Capsule of your child, as it may lead to severe side effects. If you think your child has taken too much, consult your doctor immediately. Always follow the prescribed dosage and administration instructions carefully to keep your child safe.

If your child is on insulin therapy you are recommended to consult your doctor before giving Kefnir Capsule to your child as it may change glucose levels in the blood. Always follow the doctor's instructions.

Do not give other medications along with Kefnir Capsule unless prescribed by your doctor. This medicine may interact with other medications such as lower high uric acid levels (probenecid), steroids (dexamethasone, methylprednisolone, prednisone), blood thinner (warfarin), immune suppressants (tacrolimus, ciclosporin), cholera vaccine, and typhoid vaccine.

If your child is on iron therapy, you should consult your doctor before giving Kefnir Capsule to your child, as iron may reduce the absorption of this medicine, making it less effective.

Antibiotics usually do not interfere with the components in vaccines or cause a bad reaction in a child who has just been vaccinated. However, it’s best to consult your doctor before going to treatment with Kefnir Capsule if your child is vaccinated.

The doctor may order regular kidney and liver tests to monitor your child's health and ensure their organs are working properly while taking Kefnir Capsule or having a specific medical condition.

Yellow or green mucus from a child's nose can indicate that their body is fighting off an infection, as it may contain white blood cells and other debris. However, it's always best to consult with your paediatrician for guidance and proper evaluation.

It is unknown. However, if your child has stomach pain, cramps, or very loose, watery, or bloody stools consult your doctor immediately.

The common side effects of Kefnir Capsule may include diarrhoea, nausea, vomiting, stomach pain, abnormal stools, and rash in some cases. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

INDIA

Manufacturer/Marketer address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai €“ 400 026.
Other Info - KEF0017

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