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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Kenz Tablet is an antifungal medicine used in the treatment of fungal infections such as blastomycosis, coccidioidomycosis, paracoccidioidomycosis, and histoplasmosis (lung infection caused by Histoplasma fungus). This medicine works by inhibiting the growth and multiplication of fungal cells that are responsible for the growth of infection-causing fungi.
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Composition :

KETOCONAZOLE-200MG

Manufacturer/Marketer :

Klm Laboratories Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Kenz Tablet

Kenz Tablet belongs to a class of drugs called antifungals indicated to treat various systemic fungal infections such as blastomycosis (infection caused by Blastomyces fungus), chromomycosis (chronic infection of the skin and subcutaneous tissue), Coccidioidomycosis (infection caused by Coccidioides fungus), paracoccidioidomycosis (infection caused by Paracoccidioides fungus) and histoplasmosis (lung infection caused by Histoplasma fungus). It is used only when other effective antifungal therapies are not available or tolerated and if potential benefits outweigh potential risks.

Kenz Tablet contains Ketoconazole which works by destroying fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

Take Kenz Tablet as prescribed. Your doctor will advise you on how often you need to take Kenz Tablet based on your medical condition. Some people may experience headache, nausea, stomach pain, and diarrhoea. Most of these side effects of Kenz Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Ketoconazole or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, inform your doctor before taking Kenz Tablet . Avoid breastfeeding while taking Kenz Tablet as it may be excreted in breast milk. You are recommended to avoid alcohol consumption whilst on treatment with Kenz Tablet . Kenz Tablet is not recommended for children below 2 years of age. For children above 2 years, it is recommended to use only if the doctor has determined that the benefits outweigh the risks.

Uses of Kenz Tablet

Treatment of Systemic fungal infections

Directions for Use

Take Kenz Tablet with food to avoid stomach upset or take it as advised by the doctor. Swallow the whole tablet/capsule with a glass of water. Do not break, crush or chew it.

Medicinal Benefits

Kenz Tablet is an antifungal used to treat severe fungal infections. It is used only when other effective antifungal therapies are not available or tolerated and if potential benefits outweigh potential risks. It destroys fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

How Kenz Tablet Works

Kenz Tablet contains Ketoconazole which works by destroying fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Kenz Tablet

  • Headache
  • Nausea
  • Stomach pain
  • Diarrhoea 

What if I have taken an overdose of Kenz Tablet

Never take more than the prescribed dose. When Kenz Tablet is used at high doses, it may, though unlikely, result in decreased testosterone levels, sperm production, and an issue with the adrenal glands (adrenal insufficiency). Seek emergency medical help if an overdose is suspected.

Drug Warnings

If you are allergic to Ketoconazole or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, inform your doctor before taking Kenz Tablet . Avoid breastfeeding while taking Kenz Tablet as it may be excreted in breast milk. You are recommended to avoid alcohol consumption with Kenz Tablet . If you have a loss of appetite, tiredness, stomach pain, vomiting, yellowing of skin or eyes, dark urine, or light-coloured stools, inform your doctor immediately as they might be symptoms of hepatotoxicity (liver damage). 

Drug-Drug Interactions

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KetoconazoleSilodosin
Critical
KetoconazoleMethylergometrine
Critical

Drug-Drug Interactions

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KetoconazoleSilodosin
Critical
How does the drug interact with Kenz Tablet:
Coadministration of Silodosin with Kenz Tablet may lead to side effects including extremely low blood pressure, and increased heart rate.

How to manage the interaction:
Taking Kenz Tablet with Silodosin together is not recommended as it can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, heart palpitation. Do not discontinue any medications without consulting a doctor.
KetoconazoleMethylergometrine
Critical
How does the drug interact with Kenz Tablet:
Using Kenz Tablet with Methylergometrine can increase the concentration of Methylergometrine, which may lead to side effects.

How to manage the interaction:
Taking Kenz Tablet with Methylergometrine is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
KetoconazoleDronedarone
Critical
How does the drug interact with Kenz Tablet:
When Dronedarone is taken with Kenz Tablet, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Kenz Tablet with Dronedarone is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
KetoconazoleEplerenone
Critical
How does the drug interact with Kenz Tablet:
Coadministration of Kenz Tablet with Eplerenone can increase the levels of blood potassium which can lead to kidney damage and irregular heart rate.

How to manage the interaction:
Taking Kenz Tablet with Eplerenone is not recommended as it can result in an interaction, but it can be taken if a doctor has advised it. However, if you notice any symptoms of headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, you should contact a doctor immediately. Do not stop using any medications without the doctor's advice.
KetoconazoleIvabradine
Critical
How does the drug interact with Kenz Tablet:
Coadministration of Ivabradine with Kenz Tablet can increase the risk or severity of side effects.

How to manage the interaction:
Taking Ivabradine with Kenz Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
KetoconazoleLomitapide
Critical
How does the drug interact with Kenz Tablet:
When Lomitapide is taken with Kenz Tablet, it may increase the risk of side effects.

How to manage the interaction:
Taking Kenz Tablet with Lomitapide is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor immediately. Do not stop using any medications without talking to the doctor.
KetoconazoleVenetoclax
Critical
How does the drug interact with Kenz Tablet:
When Venetoclax is taken with Kenz Tablet, it can increase the risk of side effects.

How to manage the interaction:
Taking Kenz Tablet with Venetoclax is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. if you experience nausea, vomiting, diarrhea, fatigue, bleeding problems, and infections, consult a doctor. Do not stop using any medications without talking to a doctor.
KetoconazoleNimodipine
Critical
How does the drug interact with Kenz Tablet:
When Nimodipine is taken with Kenz Tablet, it can increase the blood levels of Nimodipine which may lead to serious side effects .

How to manage the interaction:
Taking Kenz Tablet with Nimodipine is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience -irregular heart rhythm, swelling, and low blood pressure, consult the doctor. Do not discontinue any medications without consulting the doctor.
KetoconazoleEliglustat
Critical
How does the drug interact with Kenz Tablet:
When Eliglustat is taken with Kenz Tablet, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Kenz Tablet with Eliglustat is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or slow heart rate, weak pulse, or heart palpitations, consult the doctor immediately. Do not stop any medications without a doctor's advice.
KetoconazoleTicagrelor
Critical
How does the drug interact with Kenz Tablet:
Co-administration of ticagrelor with Kenz Tablet can cause severe bleeding.

How to manage the interaction:
Taking Ticagrelor with Kenz Tablet is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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KETOCONAZOLE-200MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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KETOCONAZOLE-200MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consumption of grapefruit or its juice with Kenz Tablet may result in side effects such as joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, dark urine, light colored stools, and yellowing of the skin or eyes. Avoid consuming grapefruit, grapefruit juice, or any supplements that include grapefruit extract while taking Kenz Tablet.

Diet & Lifestyle Advise

  • Avoid high-risk areas such as renovated buildings, construction sites, pigeon or chick coops, and caves.
  • Wear a respiratory mask when there is a risk of exposure to spores.
  • People with a weak immune system are advised to avoid activities that involve close contact with dust or dirt including digging, yard work, and gardening.
  • Close windows and stay inside during dust storms.
  • Clean skin injuries well with soap and water to reduce the risk of developing a skin infection.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS - ORAL

Kenz Tablet Substitute

Substitutes safety advice
  • Fungicide Tablet 10's

    by Others

    47.52per tablet
  • Phytoral Tablet 10's

    by Others

    46.08per tablet
  • Hyphoral Tablet 10's

    by Others

    34.61per tablet
  • Ketocip 200 mg Tablet 10's

    by Others

    21.78per tablet
  • Ketafung Tablet 10's

    by Others

    20.70per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Kenz Tablet as it may increase the risk of liver damage and cause adverse effects.

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Pregnancy

Caution

Kenz Tablet is a Category C pregnancy drug and is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Unsafe

Kenz Tablet may be excreted in breast milk. Therefore, it is recommended to avoid breastfeeding while taking Kenz Tablet .

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Driving

Caution

Kenz Tablet may cause dizziness or drowsiness. Therefore, drive only if you alert after taking Kenz Tablet .

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Liver

Unsafe

Kenz Tablet is contraindicated in patients with chronic or acute liver disease. Therefore, inform your doctor if you have any Liver diseases/conditions.

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Kidney

Caution

If you have any concerns regarding the use of Kenz Tablet in patients with kiver diseases/conditions, consult a doctor.

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Children

Caution

Kenz Tablet is not recommended for children below 2 years of age. For children above 2 years, it is recommended to use only if the doctor has determined that benefits outweigh risks.

FAQs

Kenz Tablet belongs to a class of drugs called antifungals indicated to treat various systemic fungal infections such as blastomycosis (infection caused by Blastomyces fungus), chromomycosis (chronic infection of the skin and subcutaneous tissue), Coccidioidomycosis (infection caused by Coccidioides fungus), paracoccidioidomycosis (infection caused by Paracoccidioides fungus) and histoplasmosis (lung infection caused by Histoplasma fungus).

Kenz Tablet works by destroying fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

Kenz Tablet is not recommended to treat fungal meningitis (fungal infection spreads to the brain and spinal cord) as it poorly penetrates into the cerebrospinal fluid. Therefore, inform your doctor if you have fungal meningitis so that appropriate medication may be prescribed.

You are recommended to avoid foods containing chocolate and caffeine such as cocoa beans, tea, coffee, cola and energy drinks while taking Kenz Tablet as it may increase the adverse effects of caffeine such as drowsiness, nervousness or nausea.

You are not recommended to take Kenz Tablet with simvastatin (lipid-lowering drug) as co-administration of these medicines may cause muscle problems. Therefore, please consult a doctor before taking Kenz Tablet with other medicines.

No, you are not recommended to stop taking Kenz Tablet without consulting your doctor as it may cause recurring infection. Therefore, take Kenz Tablet for as long as your doctor has prescribed it and if you experience any difficulty while taking Kenz Tablet , please consult your doctor.

Country of origin

INDIA

Manufacturer/Marketer address

KLM LABORATORIES PVT LTD, 1004, Hubtown Viva, Jogeshwari (E), Mumbai-400060, Maharashtra, India.
Other Info - KEN0050

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