Ketraz 200mg Tablet
MRP ₹140
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₹21.0 Cashback (15%)
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About Ketraz 200mg Tablet
Ketraz 200mg Tablet is indicated to treat various systemic fungal infections such as blastomycosis (infection caused by Blastomyces fungus), chromomycosis (chronic infection of the skin and subcutaneous tissue), Coccidioidomycosis (infection caused by Coccidioides fungus), paracoccidioidomycosis (infection caused by Paracoccidioides fungus) and histoplasmosis (lung infection caused by Histoplasma fungus).
Ketraz 200mg Tablet contains ketoconazole, which works by destroying fungal cell membranes that are essential for their survival. Thus, kills fungi and treats the fungal infection.
Some people may experience headache, nausea, stomach pain, and diarrhoea as side effects. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are allergic to ketoconazole or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, inform your doctor before taking Ketraz 200mg Tablet. Avoid breastfeeding while taking Ketraz 200mg Tablet as it may be excreted in breast milk. Ketraz 200mg Tablet is not recommended for children below 2 years of age.
Uses of Ketraz 200mg Tablet
Ketraz 200mg Tablet is used in the treatment of severe fungal infections when other antifungal treatments are unsuitable or ineffective. The detailed uses of Ketraz 200mg Tablet include:
- Treatment of systemic fungal infections: Ketraz 200mg Tablet is prescribed for serious fungal infections affecting internal organs such as the lungs, liver, or skin.
- Management of fungal infections resistant to first-line therapy: Ketraz 200mg Tablet is used when alternative antifungal agents are not tolerated or fail to provide adequate results.
- Destruction of fungal cell membranes: Ketraz 200mg Tablet works by disrupting the integrity of fungal cell membranes, leading to cell death and resolution of the infection.
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Directions for Use
- Ketraz 200mg Tablet can be taken with or without food.
- Your doctor will decide the dose and duration depending on your condition.
- Swallow the medicine as a whole with a glass of water.
- Do not crush, chew, or break Ketraz 200mg Tablet as it may affect the way the medication is absorbed.
Medicinal Benefits
- Ketraz 200mg Tablet is an antifungal used to treat severe fungal infections.
- It is used only when other effective antifungal therapies are not available or tolerated and if potential benefits outweigh potential risks.
- It destroys fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.
How Ketraz 200mg Tablet Works
Storage
- Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
- Divide your daily food intake into smaller, more frequent meals to reduce nausea.
- Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
- Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
- Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
- Use ginger (tea, ale, or candies) to help relieve nausea.
- Get adequate rest and also avoid strenuous activities that can worsen nausea.
- Talk to your doctor about taking anti-nausea medication if your nausea is severe.
- Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
What if I have taken an overdose of Ketraz 200mg Tablet
Drug Warnings
- If you are allergic to Ketoconazole or any other medicines, please tell your doctor.
- If you are pregnant or planning for pregnancy, inform your doctor before taking Ketraz 200mg Tablet.
- Avoid breastfeeding while taking Ketraz 200mg Tablet as it may be excreted in breast milk.
- You are recommended to avoid alcohol consumption with Ketraz 200mg Tablet.
- If you have a loss of appetite, tiredness, stomach pain, vomiting, yellowing of skin or eyes, dark urine, or light-coloured stools, inform your doctor immediately as they might be symptoms of hepatotoxicity (liver damage).
Drug-Drug Interactions
Drug-Drug Interactions
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Taking Ketraz 200mg Tablet and Disopyramide together can increase the risk of irregular heart rhythm.
How to manage the interaction:
Taking Ketraz 200mg Tablet with Disopyramide is not recommended as it can cause an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms like dizziness, irritation, confusion, chest pain or tightness, swelling, fatigue, palpitations, shortness of breath, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Using irinotecan together with Ketraz 200mg Tablet can increase the risk of side effects.
How to manage the interaction:
Taking Ketraz 200mg Tablet with Irinotecan is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience any symptoms such as paleness, fatigue, dizziness, fainting, unexpected bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, consult the doctor immediately.
Using Ketraz 200mg Tablet with Halofantrine can increase the chance of a serious abnormal heart rhythm.
How to manage the interaction:
Taking Ketraz 200mg Tablet with Halofantrine is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
When Triazolam is taken with Ketraz 200mg Tablet, it can increase the risk of drowsiness and slowed breathing.
How to manage the interaction:
Taking Triazolam with Ketraz 200mg Tablet is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
When Lomitapide is taken with Ketraz 200mg Tablet, it may increase the risk of side effects.
How to manage the interaction:
Taking Ketraz 200mg Tablet with Lomitapide is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor immediately. Do not stop using any medications without talking to the doctor.
Coadministration of Ketraz 200mg Tablet with Eplerenone can increase the levels of blood potassium which can lead to kidney damage and irregular heart rate.
How to manage the interaction:
Taking Ketraz 200mg Tablet with Eplerenone is not recommended as it can result in an interaction, but it can be taken if a doctor has advised it. However, if you notice any symptoms of headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, you should contact a doctor immediately. Do not stop using any medications without the doctor's advice.
Using Ketraz 200mg Tablet with Methylergometrine can increase the concentration of Methylergometrine, which may lead to side effects.
How to manage the interaction:
Taking Ketraz 200mg Tablet with Methylergometrine is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
When Dronedarone is taken with Ketraz 200mg Tablet, it can increase the chance of a serious abnormal heart rhythm.
How to manage the interaction:
Taking Ketraz 200mg Tablet with Dronedarone is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
When Naloxegol is taken with Ketraz 200mg Tablet, it can increase the blood levels of naloxegol which may cause the side effects.
How to manage the interaction:
Taking Ketraz 200mg Tablet with Naloxegol is not recommended as it can cause an interaction, but it can be taken if prescribe by the doctor. However, if you experience symptoms such as sweating, tearing, runny nose, chills, diarrhea, stomach pain, anxiety, difficulty sleeping, irritability, restlessness, and yawning, consult the doctor. Do not stop using any medications without talking to a doctor.
Co-administration of ticagrelor with Ketraz 200mg Tablet can cause severe bleeding.
How to manage the interaction:
Taking Ticagrelor with Ketraz 200mg Tablet is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Drug-Food Interactions
Drug-Food Interactions
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Grapefruit Juice, Grapefruit
How to manage the interaction:
Consumption of grapefruit or its juice with Ketraz 200mg Tablet may result in side effects such as joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, dark urine, light colored stools, and yellowing of the skin or eyes. Avoid consuming grapefruit, grapefruit juice, or any supplements that include grapefruit extract while taking Ketraz 200mg Tablet.
Diet & Lifestyle Advise
- Avoid high-risk areas such as renovated buildings, construction sites, pigeon or chick coops, and caves.
- Wear a respiratory mask when there is a risk of exposure to spores.
- People with a weak immune system are advised to avoid activities that involve close contact with dust or dirt including digging, yard work, and gardening.
- Close windows and stay inside during dust storms.
- Clean skin injuries well with soap and water to reduce the risk of developing a skin infection.
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Alcohol
Unsafe
Avoid consumption of alcohol while taking Ketraz 200mg Tablet as it may increase the risk of liver damage and cause adverse effects.
Pregnancy
Consult your doctor
Ketraz 200mg Tablet is a Category C pregnancy drug and is given to pregnant women only if the doctor thinks the benefits outweigh the risks.
Breast Feeding
Unsafe
Ketraz 200mg Tablet may be excreted in breast milk. Therefore, it is recommended to avoid breastfeeding while taking Ketraz 200mg Tablet.
Driving
Caution
Ketraz 200mg Tablet may cause dizziness or drowsiness. Therefore, drive only if you alert after taking Ketraz 200mg Tablet.
Liver
Unsafe
Ketraz 200mg Tablet is contraindicated in patients with chronic or acute liver disease. Therefore, inform your doctor if you have any Liver diseases/conditions.
Kidney
Consult your doctor
If you have any concerns regarding the use of Ketraz 200mg Tablet in patients with kiver diseases/conditions, consult a doctor.
Children
Consult your doctor
Ketraz 200mg Tablet is not recommended for children below 2 years of age. For children above 2 years, it is recommended to use only if the doctor has determined that benefits outweigh risks.
Heart
If you have any concerns regarding the use of Ketraz 200mg Tablet in patients with heart diseases/conditions, consult a doctor.
Geriatrics
Caution
Ketraz 200mg Tablet should be used with caution in elderly patients. Please consult your doctor before use.
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