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compositionComposition:CLINDAMYCIN-300MG
prescription
Prescription Medicine
info
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Klinset 300mg Capsule is an antibiotic medicine used in the treatment of bacterial infections. This medicine contains clindamycin, which works by inhibiting protein synthesis in bacterial cells and thereby helps fight infection-causing bacteria. This medicine is not effective for treating viral infections. Common side effects include stomach pain, nausea, vomiting, diarrhoea, heartburn, and skin rash.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

CLINDAMYCIN-300MG

Manufacturer/Marketer :

Duken Pharmaceuticals

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Klinset 300mg Capsule

Klinset 300mg Capsule is an antibiotic used to treat a wide variety of serious bacterial infections. It works by stopping the growth of bacteria in areas like the lungs, skin, bones, joints, and internal organs. Doctors prescribe this medicine to clear up infections that other antibiotics may not be able to treat effectively.

For the best results, you must take this medicine at evenly spaced times throughout the day and complete the entire course exactly as prescribed. You can take it with or without food, but taking it with a full glass of water is highly recommended to prevent throat irritation. Drinking plenty of fluids and getting adequate rest during your treatment helps your body recover faster.

While taking Klinset 300mg Capsule, you may experience mild side effects like nausea, vomiting, or mild diarrhoea. However, if you develop severe, watery diarrhoea, stomach cramps, or signs of an allergic reaction like a skin rash, you should contact your doctor immediately.

Before starting this medicine, tell your doctor if you have a history of bowel disease (such as colitis), liver damage, or kidney problems. Do not take this if you have ever had a severe allergic reaction to it or similar antibiotics.

This medication can interact with other drugs like muscle relaxants used during surgery, potentially making them stronger and more dangerous. If you are pregnant, breastfeeding, or an older adult, consult your doctor or pharmacist to discuss the risks and benefits of using this medicine.

Uses of Klinset 300mg Capsule

Klinset 300mg Capsule is used to treat a wide variety of serious bacterial infections. The detailed uses of Klinset 300mg Capsule are as follows:

  • Serious respiratory tract infections: Klinset 300mg Capsule helps clear serious infections in your lungs, such as pneumonia or lung abscesses, by stopping the underlying bacterial growth.
  • Skin and soft tissue infections: It is used to treat severe skin infections, deep tissue wounds, and abscesses that are resistant to other treatments.
  • Bone and joint infections: It penetrates deeply into bone tissues to eliminate persistent bacterial infections like osteomyelitis.
  • Dental infections: Doctors and dentists prescribe it to treat severe tooth abscesses and jaw infections when first-line treatments are not suitable.
  • Intra-abdominal and pelvic infections: It helps treat complex infections within the abdomen and pelvis by targeting specific bacteria that thrive without oxygen.

Key Benefits

Klinset 300mg Capsule helps treat bacterial infections by eliminating the bacteria causing the illness. With regular use as prescribed, it helps relieve symptoms, promotes faster recovery, and reduces the risk of infection-related complications.

  • Clears Bacterial Infections: By stopping the growth of infection-causing bacteria, this medicine helps reduce symptoms such as fever, pain, redness, swelling, and discomfort, allowing you to recover more quickly.
  • Promotes Faster Recovery: As the infection clears, this medicine supports the body's natural healing process, helping you return to your normal daily activities sooner.
  • Helps Prevent Recurrence: Completing the full course of treatment helps eliminate the infection completely, reducing the risk of the infection returning and helping prevent the development of antibiotic-resistant bacteria.
Side effects of Klinset 300mg Capsule
  • Take cold water baths avoiding soap.
  • Avoid scratching and scrubbing to prevent infections while itching.
  • Use nets to prevent insects and mosquitoes.
  • Stop using lotions and creams that cause irritation.
  • Avoid alcohol and caffeine intake.
  • Abnormal liver function requires immediate medical attention. Your doctor may recommend lifestyle modifications along with needed medication.
  • Avoid intake of alcohol as it has a direct impact on liver functioning.
  • Prevent medications like paracetamol, over-the-counter painkillers or those mentioned by your doctor, as they may have issues getting metabolised in your body.
  • If you have overweight issues, losing weight can be a good thing to manage abnormal liver function.
  • Cut down the number of fatty foods that are taken daily.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.

Directions for Use

  • Take Klinset 300mg Capsule with or without food as advised by your doctor.
  • It is advised to take Klinset 300mg Capsule 3 to 4 times daily; however, follow your doctor's advice regarding the dosage and duration.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, chew, or break the medicine.

How Klinset 300mg Capsule Works

Klinset 300mg Capsule contains clindamycin, which belongs to a class of medicines known as lincosamide antibiotics. It works by binding to a specific part of the bacteria's cellular machinery, which prevents them from producing the essential proteins they need to grow and multiply. Without these proteins, the bacteria cannot survive or spread, allowing your body's natural immune system to easily destroy the remaining germs and clear the infection.
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Alcohol

Caution

Avoid taking alcohol while using Klinset 300mg Capsule since it may worsen the side effects.

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Pregnancy

Consult your doctor

Please consult your doctor before taking Klinset 300mg Capsule if you are pregnant or planning to conceive.

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Breast Feeding

Consult your doctor

Klinset 300mg Capsule is not recommended during breastfeeding since it can be excreted into breast milk. Please consult your doctor before taking Klinset 300mg Capsule if you are breastfeeding.

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Driving

Safe if prescribed

Klinset 300mg Capsule usually does not interfere with your driving ability.

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Liver

Consult your doctor

Let your doctor know if you have any history of liver diseases before taking Klinset 300mg Capsule since it may cause jaundice and abnormal liver function tests.

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Kidney

Consult your doctor

Let your doctor know if you have any history of kidney diseases before taking Klinset 300mg Capsule.

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Children

Consult your doctor

Klinset 300mg Capsule should be used in children only when prescribed by a doctor. Your doctor will prescribe the dose depending on the child's age and body weight.

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Heart

Consult your doctor

Please consult your doctor before using Klinset 300mg Capsule if you have pre-existing heart problems. Your doctor will prescribe Klinset 300mg Capsule if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Limited information available about the use of Klinset 300mg Capsule in geriatric patients. Please consult your physician.

What if I have taken an overdose of Klinset 300mg Capsule

If you or someone else takes too much of this medicine, seek immediate medical attention or contact a nearby medical centre right away.

Diet & Lifestyle Advise

  • Drink plenty of fluids: Ensure you drink a full glass of water with each dose and stay hydrated throughout the day to protect your throat and stomach from irritation.
  • Support your gut health: Consider taking a probiotic supplement or eating yoghurt with active cultures a few hours after your antibiotic dose to help maintain a healthy balance of gut bacteria.
  • Avoid alcohol: While alcohol does not directly stop the medicine from working, it can worsen side effects like stomach upset and dizziness, and may slow down your body's natural recovery process.
  • Do not use anti-diarrhoea medicines: If you develop diarrhoea while taking this antibiotic, do not take over-the-counter anti-diarrhoea medications without asking a doctor, as they can make severe bowel conditions worse.
health query

Have a query?

How Soon It Starts Working

  • The time required for Klinset 300mg Capsule to start to work: Klinset 300mg Capsule ideally shows its action within 45 minutes after administration.
  • The time for which the effects of Klinset 300mg Capsule last: The effect of Klinset 300mg Capsule lasts for 6 to 8 hours.

What if you forget to take Klinset 300mg Capsule

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and return to your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store Klinset 300mg Capsule capsules at room temperature, between 20°C to 25°C (68°F to 77°F), in a dry place away from direct sunlight and moisture. • Do not store them in the bathroom cabinet.

Drug Warnings

  • Watch for severe diarrhoea: Be alert for watery or bloody stools, which can be a sign of a serious gut infection. This can occur during treatment or up to 8 weeks after you finish taking the antibiotic.
  • Do not lie down immediately: Stay upright for at least 30 minutes after swallowing your capsule to prevent severe irritation or ulcers in your oesophagus.
  • Finish the entire course: Never stop taking this medicine early, even if your symptoms clear up, as the remaining bacteria can multiply and cause a stronger, drug-resistant infection.
  • Inform surgical teams: Tell your doctor or anesthesiologist that you are taking Klinset 300mg Capsule if you are scheduled for any surgery, as it can interact with drugs used to relax your muscles during procedures.

Drug-Drug Interactions

verifiedApollotooltip
  • Neuromuscular blocking agents: Klinset 300mg Capsule may increase the effects of muscle relaxants used during surgery, which can affect your breathing.
  • Erythromycin: Taking these two antibiotics together can reduce the effectiveness of Klinset 300mg Capsule because they compete for the same target in bacteria.
  • Oral contraceptives: Current evidence does not support a clinically significant reduction in the effectiveness of hormonal contraceptives with clindamycin. However, if you experience severe vomiting or diarrhoea while taking this medicine, absorption of oral contraceptives may be reduced. If you have concerns, discuss contraception with your doctor or pharmacist.
ClindamycinFosphenytoin
Severe
ClindamycinBoceprevir
Severe

Drug-Drug Interactions

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ClindamycinFosphenytoin
Severe
How does the drug interact with Klinset 300mg Capsule:
When Klinset 300mg Capsule is taken with Fosphenytoin, it can cause the body to process Klinset 300mg Capsule faster.

How to manage the interaction:
Although there is a possible interaction between Klinset 300mg Capsule and Fosphenytoin, you can take these medicines together if prescribed by your doctor. If you notice any symptoms like sudden drowsiness, fatigue, confusion, itching, burning, or tingling sensation, abnormal body movements, or loss of coordination, make sure to contact your doctor right away. Do not stop using any medications without first talking to your doctor.
ClindamycinBoceprevir
Severe
How does the drug interact with Klinset 300mg Capsule:
Co-administration of Boceprevir together with Klinset 300mg Capsule can increase the effects of Klinset 300mg Capsule.

How to manage the interaction:
Although there is a possible interaction between Klinset 300mg Capsule and Boceprevir, you can take these medicines together if prescribed by your doctor. If you have ongoing feelings of sickness, throwing up, having loose stools, or pain in your stomach, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
ClindamycinEstradiol
Severe
How does the drug interact with Klinset 300mg Capsule:
When taken in combination, Klinset 300mg Capsule can lower the amount or action of estradiol.

How to manage the interaction:
Co-administration of Estradiol with Klinset 300mg Capsule can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
ClindamycinEthinylestradiol
Severe
How does the drug interact with Klinset 300mg Capsule:
When Ethinylestradiol and Klinset 300mg Capsule are taken together, the effects of Klinset 300mg Capsule can be reduced.

How to manage the interaction:
There may be a possibility of interaction between Ethinylestradiol and Klinset 300mg Capsule, but it can be taken if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ClindamycinAtracurium
Severe
How does the drug interact with Klinset 300mg Capsule:
Co-administration of Klinset 300mg Capsule with Atracurium can increase the risk of muscle weakness.

How to manage the interaction:
Taking Klinset 300mg Capsule with Atracurium together can possibly result in an interaction, but it can be taken if a doctor has advised it. "Klinset 300mg Capsule can affect the muscles and nerves in your body. When used with other medications that also affect the muscles and nerves, it can cause a serious problem called neuromuscular blockade. If you have trouble breathing or can't breathe at all, please call your doctor right away." Do not stop using any medications without a doctor's advice.
ClindamycinBalsalazide
Severe
How does the drug interact with Klinset 300mg Capsule:
Co-administration of Klinset 300mg Capsule with Balsalazide may reduce the effectiveness of Balsalazide.

How to manage the interaction:
Although there is a possible interaction, Klinset 300mg Capsule can be taken with balsalazide if prescribed by the doctor. Consult the prescriber if you have any concerns, the doctor may prescribe alternatives that do not interact, dose adjustment, or more frequent monitoring to safely use both medications. Do not discontinue the medication without consulting a doctor.
ClindamycinItraconazole
Severe
How does the drug interact with Klinset 300mg Capsule:
Concomitant use of Klinset 300mg Capsule with itraconazole can reduce the metabolism and increase the levels of Klinset 300mg Capsule in the body. This may increase the risk or severity of side effects.

How to manage the interaction:
Although there is a possible interaction, Klinset 300mg Capsule can be taken with itraconazole if prescribed by the doctor. Consult a doctor immediately if you experience persistent vomiting, nausea, abdominal pain, or diarrhea. Do not stop using any medications without first talking to your doctor.
ClindamycinCholera, live attenuated
Severe
How does the drug interact with Klinset 300mg Capsule:
Co-administration of Klinset 300mg Capsule may reduce the activity of the cholera vaccine.

How to manage the interaction:
Talk to your doctor before receiving the Cholera vaccine if you are currently being treated with Klinset 300mg Capsule or have been treated within the last 14 days. To ensure adequate vaccine response, you should not receive cholera vaccine until at least 14 days after you complete antibiotic therapy. Do not discontinue the medication without consulting a doctor.
ClindamycinBacitracin
Severe
How does the drug interact with Klinset 300mg Capsule:
Co-administration of Klinset 300mg Capsule with Bacitracin may increase the risk of kidney and/or nerve damage.

How to manage the interaction:
Although there is a possible interaction, Klinset 300mg Capsule can be taken with bacitracin if prescribed by the doctor. Consult the prescriber if you experience signs and symptoms of kidney damage such as sudden weight gain or weight loss, nausea, vomiting, fluid retention, loss of appetite, increased or decreased urination, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Let your doctor know if you develop seizures; hearing problems; or numbness, burning or tingling in your hands and feet. If you develop diarrhoea or vomiting during treatment with these medications, drink plenty of fluids to prevent dehydration, as dehydration may harm the kidney.
ClindamycinCeritinib
Severe
How does the drug interact with Klinset 300mg Capsule:
Concomitant use of Klinset 300mg Capsule with ceritinib can increase the effects of Klinset 300mg Capsule

How to manage the interaction:
Although there is a possible interaction, Klinset 300mg Capsule can be taken with ceritinib if prescribed by the doctor. Consult the prescriber if you experience persistent vomiting, nausea, abdominal pain, or diarrhoea.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Klinset 300mg Capsule when used as directed. 
 

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Klinset 300mg Capsule is used to treat bacterial infections.
Klinset 300mg Capsule is an antibiotic that treats bacterial infections. It works by inhibiting bacterial protein synthesis, which retards bacterial growth.
Klinset 300mg Capsule should be used with proper caution and doctor consultation if you have any liver or kidney disease, gastrointestinal diseases (colitis, an inflammation of the colon), yellow food dye allergy, or allergic conditions (asthma, hay fever, eczema).
Klinset 300mg Capsule can affect live vaccines, like the typhoid vaccine, and decrease their effectiveness. Please consult a doctor before you start Klinset 300mg Capsule if you are due to undergo any vaccinations.
Klinset 300mg Capsule may cause abnormal liver function tests as one of its side effects. Please consult your doctor before starting Klinset 300mg Capsule if you have any history of liver problems.
It is recommended to complete the course of Klinset 300mg Capsule even if you feel better, as it is an antibiotic, and stopping it midway may lead to recurring infections.
Diarrhoea can be a side-effect of Klinset 300mg Capsule. Drink enough fluids and eat non-spicy food if you experience diarrhoea. If you find blood in your stools (tarry stools) or experience severe diarrhoea, consult your doctor. Do not take anti-diarrhoeal medicine on your own.
Yes, you can take Klinset 300mg Capsule with or without food. If you experience stomach upset, taking it with a meal can help ease your symptoms. Make sure to drink a full glass of water with each dose. Talk to your doctor or pharmacist if you experience persistent stomach issues.
While alcohol does not directly stop Klinset 300mg Capsule from working, it is best to avoid it during your treatment. Alcohol can increase side effects like nausea and dizziness, and can dehydrate your body, slowing down your recovery. Talk to your doctor for personalised advice.
Klinset 300mg Capsule should only be used during pregnancy if it is clearly needed and prescribed by your healthcare provider. Your doctor will weigh the benefits of treating your infection against any potential risks to the baby. Talk to your doctor if you are pregnant or planning to become pregnant.
No, Klinset 300mg Capsule is an antibiotic and is only effective against bacterial infections. It will not work for viral infections like colds, flu, or bronchitis caused by viruses. Using antibiotics when they are not needed increases the risk of drug-resistant infections. Talk to your doctor about the right treatment for your symptoms.
No, you should not lie down for at least 30 minutes after taking Klinset 300mg Capsule. Staying upright helps the capsule pass smoothly into your stomach and prevents it from irritating or damaging your throat and oesophagus. Talk to your doctor or pharmacist if you have difficulty swallowing pills.
Current evidence indicates that clindamycin does not have a clinically significant interaction with hormonal contraceptives. However, if you develop severe vomiting or diarrhoea during treatment, oral contraceptive absorption may be affected. If you have questions about contraception while taking this medicine, speak with your doctor or pharmacist.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Drugs.com Clinical Review Team. Clindamycin Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  2. WebMD Medical Reference Review Board. Details Drug and Treatment Monograph. Atlanta, GA: WebMD; 2026. [Accessed on 02 Jun. 2026]Check here
  3. Clindamycin phosphate [Package Leaflet]. 2023. [Accessed on 20 Feb. 2024]Check here
  4. Clindamycin Phosphate Gel [Prescribing Information]. 2021. [Accessed on 21 Oct. 2024]Check here
  5. Clindamycin Topical: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2022 [Accessed on 31 Oct 2025]Check here
  6. Clindagel® (clindamycin phosphate) topical gel, 1%For Topical Use Only [Internet]. Dailymed.nlm.nih.gov. 2022 [Accessed on 31 Oct 2025]Check here
  7. Patrick B, Murphy, Karlyle G. Bistas, Jacqueline K.Le. Clindamycin. National Library of medicine, National center for biotechnology information. [Revised in July 2021] [Accessed on 11th May 2022]Check here

Country of origin

India
Other Info - KLIN272
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