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K-Mac Oral Solution is used to treat renal tubular acidosis and kidney stones. It contains Magnesium citrate and Potassium citrate which prevents the crystallisation, growth and accumulation of stone-forming salts. In some cases, this medicine may cause side effects such as abdominal discomfort, diarrhoea, nausea, and vomiting. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Fourrts India Laboratories Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About K-Mac Oral Solution

The medication K-Mac Oral Solution is primarily prescribed to help prevent the formation of kidney stones and manage highly acidic urine. Modifying the acid level in your urine helps create an environment where stone-forming minerals are less likely to crystallize. It is commonly used for individuals prone to recurring kidney stones.

To achieve the best results, you must take K-Mac Oral Solution consistently at the exact frequency prescribed by your doctor. This medication should be taken during or after meals to reduce the risk of stomach irritation. Alongside taking your medicine regularly, drinking plenty of water and lowering your dietary salt intake can significantly improve your treatment outcomes.

While taking K-Mac Oral Solution , some people may experience mild side effects like a temporary upset stomach, mild nausea, or loose stools. However, if you experience more serious symptoms such as severe abdominal pain, muscle weakness, or a slow, irregular heartbeat, you must contact your doctor immediately. Your healthcare team can help manage these effects or adjust your therapy as needed.

Before starting this medication, talk to your doctor if you have a history of kidney issues, heart problems, or high levels of minerals in your blood. Do not take this if you suffer from severe kidney failure, untreated Addison's disease, or severe dehydration. These conditions can increase your risk of developing dangerous mineral imbalances while taking this medicine.

Some medicines, such as blood pressure drugs or certain water pills, can interact with K-Mac Oral Solution and cause dangerous build-ups of minerals in your system. It is also wise to limit alcohol consumption, as it can worsen stomach irritation and dehydration. If you are pregnant, breastfeeding, or an older adult, talk to your doctor or pharmacist to ensure this treatment is safe for your specific situation.

Uses of K-Mac Oral Solution

Your doctor may prescribe this medicine to treat several conditions, including:

  • Kidney Stone Prevention: This medicine raises the levels of protective citrate in your urine, which helps prevent stone-forming minerals from sticking together to form painful stones.
  • Urine Alkalization: It helps neutralize high acid levels in your urine, making it harder for acid-based crystals to grow into stones.
  • Renal Tubular Acidosis Management: Helps address chemical imbalances in your blood and urine caused by certain kidney conditions that impair normal acid excretion. This medicine may be used as part of treatment for certain people. Whether it's suitable depends on your condition and medical evaluation.
  • Rosacea: In some formulations, azelaic acid is also used to help reduce the redness and bumps associated with mild to moderate rosacea. Your doctor will prescribe the medicine based on your specific skin condition.

Key Benefits

K-Mac Oral Solution provides the following benefits when used as prescribed:

  • Supports Long-Term Relief: By maintaining a balanced urinary environment, K-Mac Oral Solution provides long-term relief from recurring kidney stones.
  • Helps Prevent Stones: Keeping your urine less acidic may help dissolve uric acid stones and reduce the risk of new stones forming or shrink small crystals before they can stick together, reducing the frequency of painful stone passages and allowing existing small particles to pass more comfortably. It doesn't dissolve most calcium oxalate stones
  • Protects Long-Term Kidney Health: This therapy also helps protect your kidneys from chronic mineral build-up. By preventing crystals from depositing in your kidney tissues, K-Mac Oral Solution plays a vital role in preserving long-term kidney function and preventing the inflammation or scarring that recurrent stones can cause.
Side effects of K-Mac Oral Solution 450 ml
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Limit fruit intake to two servings a day, choose a low-potassium options like apples and strawberries.
  • Restrict starchy vegetables like potatoes and pumpkin to half a cup daily.
  • Avoid or limit foods like tomato products, high-bran cereals, and salty or sugary snacks.
  • Limit dairy products to 200g of yoghurt or 300ml of milk per day.

Directions for Use

  • K-Mac Oral Solution can be taken after meals or as advised by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Check the label for directions before use.
  • Mix the advised dose of K-Mac Oral Solution with a glass of water as directed and take it orally.
  • Shake the bottle well before use.

How K-Mac Oral Solution Works

The medication K-Mac Oral Solution contains two active mineral components that work together to balance your urinary tract chemistry. The first component, after it's absorbed, potassium citrate is processed by your body to produce the bicarbonate, which makes your blood and urine more alkaline (less acidic). This reduction in acid levels helps keep stone-forming substances completely dissolved in the urine. The second component, magnesium citrate, provides a vital mineral that may help to bind oxalate in your digestive tract. By binding to oxalate in the gut before it reaches your kidneys, this mineral may help reduce the amount of stone-forming material excreted in your urine. Together, these two components work hand in hand to disrupt the crystallization process, keeping your urinary tract clear. This medicine is mainly used to help prevent uric acid and calcium oxalate kidney stones. Your Doctor will decide if it's suitable based on the type of kidney stone you have.
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Alcohol

Caution

It is not known if alcohol interacts with K-Mac Oral Solution . Please consult a doctor.

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Pregnancy

Caution

K-Mac Oral Solution belongs to pregnancy category C. Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking K-Mac Oral Solution ; your doctor will decide whether K-Mac Oral Solution can be taken by breastfeeding mothers or not.

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Driving

Safe if prescribed

K-Mac Oral Solution is unlikely to affect your ability to drive. However, you are advised to drive only if you are alert.

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Liver

Caution

Limited information is available regarding the usage of K-Mac Oral Solution in patients with hepatic impairment. Please consult your doctor.

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Kidney

Unsafe

K-Mac Oral Solution might cause soft tissue calcification and hyperkalaemia in patients with renal insufficiency. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

The safety and effectiveness of K-Mac Oral Solution in children have not been established.

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Heart

Caution

K-Mac Oral Solution should be taken with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems before using K-Mac Oral Solution .

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Geriatrics

Caution

K-Mac Oral Solution should be used with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using K-Mac Oral Solution .

What if I have taken an overdose of K-Mac Oral Solution

In case of an accidental overdose, seek emergency medical care immediately. Symptoms of an overdose may include extreme muscle weakness, a very slow heart rate, severe diarrhea, or confusion.

Diet & Lifestyle Advise

  • Prioritize Hydration: Drink at least 8 to 10 full glasses of water daily to keep your urine diluted and help flush out crystals.
  • Cut back on Dietary Salt: Limit your daily sodium intake, as high salt levels cause your kidneys to excrete more calcium, increasing the risk of stone formation.
  • Manage Your Protein Intake: Avoid excessive amounts of animal protein, which can increase the acidity of your urine and promote stone growth.
  • Maintain Dietary Calcium: Unless advised otherwise, consume standard amounts of calcium-rich foods, as calcium binds to oxalate in your gut to prevent it from entering your kidneys.
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How Soon It Starts Working

The time required for K-Mac Oral Solution to start to work: K-Mac Oral Solution ideally shows its action within 30 minutes to 6 hours after administration. The time for which the effects of K-Mac Oral Solution last: The duration of action for K-Mac Oral Solution is clinically unknown.

What if you forget to take K-Mac Oral Solution

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store K-Mac Oral Solution at room temperature, between 15°C and 30°C (59°F to 86°F).

Drug Warnings

  • Always Dilute the Liquid: If taking the liquid form, never swallow it undiluted, as it can cause severe irritation to your throat and stomach
  • Avoid Potassium-Rich Salt Substitutes: Do not use salt substitutes containing potassium, as they can cause dangerous mineral imbalances in your blood.
  • Monitor your Urine pH: If your doctor has asked you to track your urine acidity at home, record the readings consistently and bring them to your check-ups.
  • Watch for Signs of Mineral Buildup: Stop taking the medication and seek medical advice if you experience sudden, unexplained muscle cramps, weakness, or fatigue.

Drug-Drug Interactions

verifiedApollotooltip

Some medicines may affect how K-Mac Oral Solution works or increase the risk of side effects:

  • ACE inhibitors and ARBs (blood pressure medications): May increase potassium levels in your blood to unsafe levels when taken with K-Mac Oral Solution .
  • Potassium-Sparing Water Pills (diuretics): Taking these alongside K-Mac Oral Solution can significantly raise your risk of developing high blood potassium.
  • Antacids containing Aluminum or Magnesium: These can interfere with the absorption of your medication or cause an excess of magnesium.

Drug-Drug Interactions

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How does the drug interact with K-Mac Oral Solution 450 ml:
Taking Magnesium citrate and Potassium citrate (in tablet or capsule form) together with Mepenzolate can increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Taking K-Mac Oral Solution 450 ml with Mepenzolate is not recommended, as it may lead to an interaction, it can be taken if prescribed by a doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with K-Mac Oral Solution 450 ml:
Taking K-Mac Oral Solution 450 ml together with Meclizine can increase the risk stomach ulcers and bleeding.

How to manage the interaction:
Taking K-Mac Oral Solution 450 ml with Meclizine is not recommended, as it may lead to an interaction, it can be taken if prescribed by a doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Critical
How does the drug interact with K-Mac Oral Solution 450 ml:
Taking K-Mac Oral Solution 450 ml(in tablet or capsule form) together with Orphenadrine(citrate) can increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Taking K-Mac Oral Solution 450 ml with Orphenadrine (citrate) is not recommended, as it may lead to an interaction, it can be taken if prescribed by a doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with K-Mac Oral Solution 450 ml:
Taking K-Mac Oral Solution 450 ml(in tablet or capsule form) together with Tolterodine can increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Taking K-Mac Oral Solution 450 ml with Tolterodine is not recommended, as it may lead to an interaction, it can be taken if prescribed by a doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with K-Mac Oral Solution 450 ml:
Taking K-Mac Oral Solution 450 ml (in tablet or capsule form)together with Mesoridazine can increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Co-administration of K-Mac Oral Solution 450 ml with Mesoridazine is not recommended, as it may lead to an interaction, it can be taken if prescribed by a doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with K-Mac Oral Solution 450 ml:
Taking K-Mac Oral Solution 450 ml together with Procyclidine can increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Taking K-Mac Oral Solution 450 ml with procyclidine is not recommended, but it can be taken together if advised by your doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with K-Mac Oral Solution 450 ml:
Taking Diphenhydramine with Magnesium citrate and Potassium citrate together can increase the risk of stomach ulcers, bleeding.

How to manage the interaction:
Taking Diphenhydramine with Magnesium citrate and Potassium citrate is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with K-Mac Oral Solution 450 ml:
Taking K-Mac Oral Solution 450 ml (in tablet or capsule form) together with Scopolamine can increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Taking K-Mac Oral Solution 450 ml with Scopolamine is not recommended, as it may lead to an interaction but can be taken if prescribed by a doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with K-Mac Oral Solution 450 ml:
Co-administration of K-Mac Oral Solution 450 ml with Glycopyrrolate can increase the risk or severity of ulcers and bleeding.

How to manage the interaction:
Taking K-Mac Oral Solution 450 ml together with Glycopyrrolate is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with K-Mac Oral Solution 450 ml:
Taking K-Mac Oral Solution 450 ml (in tablet or capsule form) together with Triprolidine can increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Taking K-Mac Oral Solution 450 ml with Triprolidine is not recommended, as it may lead to an interaction, it can be taken if prescribed by a doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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The following foods and drinks may affect how K-Mac Oral Solution works or increase the risk of side effects:

Salt Substitutes: Using salt alternatives that contain potassium can lead to dangerously high blood potassium levels.
High-Sodium Diet: Consuming excess sodium directly counteracts the stone-preventative benefits of K-Mac Oral Solution .

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Therapeutic Class

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FAQs

K-Mac Oral Solution contains Magnesium citrate and Potassium citrate. K-Mac Oral Solution raises the urinary pH, potassium, magnesium and citric acid levels; this prevents the crystallisation of stone-forming salts.
No. Do not stop taking K-Mac Oral Solution without consulting your doctor, even if your kidney stones have disappeared or you feel well. The medicine continues to help prevent new stones from forming, so it should be taken for as long as your doctor prescribes. If you have concerns or experience side effects, speak with your doctor before stopping treatment.
Avoid taking K-Mac Oral Solution if you have peptic ulcers as K-Mac Oral Solution has ulcerogenic potential, which could lead to further ulceration.
Yes. Diarrhoea can occur as a side effect of K-Mac Oral Solution , especially when starting treatment. To help reduce it, take the medicine with meals and, if using the liquid form, dilute it completely in water or juice before taking it. Drink plenty of fluids to stay hydrated and avoid taking anti-diarrhoeal medicines unless advised by your doctor. If the diarrhoea is severe, persistent, or accompanied by blood or black tarry stools, seek medical attention promptly.
Consult a doctor before taking K-Mac Oral Solution if you have an active urinary tract infection, as K-Mac Oral Solution increases the urinary pH, which might promote further bacterial growth.
No, it is highly recommended to take K-Mac Oral Solution during or after a meal, or with a bedtime snack. Taking it with food or diluting it properly helps prevent stomach upset and diarrhea. Talk to your doctor or pharmacist if you experience persistent stomach discomfort.
No, you must avoid using salt substitutes that contain potassium while taking K-Mac Oral Solution . Combining them can lead to a dangerously high concentration of potassium in your bloodstream. Talk to your doctor or pharmacist about safe diet alternatives.
You should only take K-Mac Oral Solution during pregnancy if it is clearly prescribed by your healthcare provider. Your doctor will weigh the benefits of preventing kidney stones against any potential risks to your pregnancy. Talk to your doctor to discuss your treatment.
You should generally aim to drink at least 2 to 3 liters (8 to 10 glasses) of water daily while taking K-Mac Oral Solution . Staying highly hydrated is critical because it works alongside the medication to keep stone-forming minerals diluted. Talk to your doctor about your specific fluid intake goals.
Signs of high blood potassium include muscle weakness, tingling or numbness in your hands and feet, a slow or irregular pulse, and severe fatigue. If you notice any of these symptoms, seek medical help immediately. Talk to your doctor if you have concerns about your mineral levels.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

#1, Fourrts Avenue, Annai Indira Nagar, Okkiyam Thoraipakkam, Chennai, India.
Other Info - KMA0002
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