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Kolder DMR 100ml Syp is a combination medicine which belongs to the class of expectorants. It is used in the treatment of dry cough and also sometimes to relieve allergic symptoms. This medicine works by preventing nerve signals from the brain's cough centre from reaching the muscles that cause coughing and thus reduce cough. Some people may experience side effects like dry mouth, throat or nose, drowsiness, blurred vision, constipation, dizziness, restlessness, or excitation

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CHLORPHENIRAMINE MALEATE-2MG+DEXTROMETHORPHAN-10MG+PHENYLEPHRINE-5MG

Manufacturer/Marketer :

Klokter Life Sciences Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Kolder DMR 100ml Syp

Kolder DMR 100ml Syp is used to treat dry cough. Coughing is the body's way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. A dry cough is tickly and doesn't produce any viscous or thick mucus, while a chesty cough (wet cough) means mucus or sputum is created to help clear the airways.

Kolder DMR 100ml Syp is a combination of Chlorpheniramine, Phenylephrine, and Dextromethorphan. Chlorpheniramine works by blocking the action of histamine. Phenylephrine helps in shrinking the blood vessels located in the nasal passage. Dextromethorphan works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce a cough.

Some people may experience dry mouth, throat, or nose, as well as drowsiness, blurred vision, constipation, dizziness, restlessness, or excitation. Most of these side effects do not require medical attention. However, if the side effects persist or worsen, please consult your doctor.

If you are pregnant or breastfeeding, it is advised to inform your doctor before using Kolder DMR 100ml Syp. Avoid using Kolder DMR 100ml Syp if you have taken monoamine oxidase inhibitors in the past 14 days. If you have glaucoma, urinary problems, enlarged prostate, phenylketonuria (a congenital disability that causes accumulation of amino acid, phenylalanine in the body), cough with mucus or cough caused by asthma, smoking, inform your doctor before taking it.

Uses of Kolder DMR 100ml Syp

Kolder DMR 100ml Syp is used to treat dry cough and symptoms of upper respiratory tract infections and allergies. The detailed uses of Kolder DMR 100ml Syp are as follows:

  • Dry cough: Kolder DMR 100ml Syp contains a cough suppressant that acts on the brain’s cough center to reduce dry, irritating cough.
  • Treatment of common cold symptoms: Kolder DMR 100ml Syp reduces nasal congestion, runny nose, and sneezing caused by viral infections.
  • Upper respiratory tract infections: Kolder DMR 100ml Syp provides relief in conditions like pharyngitis, laryngitis, and other non-bacterial infections.
  • Relief from allergy-related symptoms: Kolder DMR 100ml Syp used to treat symptoms like itchy nose, watery eyes, and sneezing due to allergic rhinitis.

Key Benefits

  • Kolder DMR 100ml Syp contains Chlorpheniramine maleate, Phenylephrine, and Dextromethorphan used to treat dry cough. 
  • Chlorpheniramine maleate helps to provide relief from allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness.
  • Phenylephrine helps in shrinking the blood vessels located in the nasal passage, thereby reducing the stuffy nose. 
  • Dextromethorphan works by blocking the transmission of nerve signals from the cough center in the brain to the muscles that produce cough.
  • Thus, Kolder DMR 100ml Syp helps to relieve overall cough, cold and allergic symptoms.
Side effects of Kolder DMR 100ml Syp
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Try to get 7-9 hours of sleep per night.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is cool, quiet and dark to maximize your sleep quality.
  • Get plenty of sunlight in the morning.
  • Do moderate-intensity exercises most days of the week and avoid strenuous exercise close to bedtime.
  • Limit processed foods and sugary drinks.
  • Avoid caffeine late in the day and drink in moderation in the morning.
  • Take short nap (20 to 30 minutes) mid-afternoon if required.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.

Directions for Use

  • Kolder DMR 100ml Syp can be taken with or without food as advised by the doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Measure the prescribed dose using a measuring cup and administer it orally.
  • Shake well before each use.

How Kolder DMR 100ml Syp Works

Kolder DMR 100ml Syp is a combination of three drugs, namely: Chlorpheniramine maleate (antihistamine), Phenylephrine (decongestant), and Dextromethorphan (cough suppressant). Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine helps in shrinking the blood vessels located in the nasal passage, thereby reducing the stuffy nose. Dextromethorphan works by blocking the transmission of nerve signals from the cough center in the brain to the muscles that produce cough. Collectively, it helps to provide relief from dry cough.
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Alcohol

Consult your doctor

Avoid consumption of alcohol with Kolder DMR 100ml Syp as it may increase drowsiness. Please consult a doctor before consuming alcohol with Kolder DMR 100ml Syp.

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Pregnancy

Consult your doctor

The safety of Kolder DMR 100ml Syp in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

It is unknown whether Kolder DMR 100ml Syp is excreted in human milk. Kolder DMR 100ml Syp is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

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Driving

Caution

Kolder DMR 100ml Syp may cause dizziness or drowsiness in some people. Therefore, drive only if you are alert after taking Kolder DMR 100ml Syp.

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Liver

Caution

Take Kolder DMR 100ml Syp with caution, especially if you have a history of liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Kolder DMR 100ml Syp with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Consult your doctor

Kolder DMR 100ml Syp is not recommended for children below 4 years of age. However, please consult a doctor before using Kolder DMR 100ml Syp in children.

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Heart

Caution

Kolder DMR 100ml Syp should be taken with caution in patients with heart problems. Your doctor will prescribe only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Please consult a doctor before giving this medication to geriatric patients due to the risk of side effects.

What if I have taken an overdose of Kolder DMR 100ml Syp

Do not take more than the prescribed dose of Kolder DMR 100ml Syp as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Avoid dairy products such as milk, as it may increase mucus production. Also, avoid processed or refined foods to have relief from cough.
  • Drink plenty of fluids to avoid dry throat while you have a cough and loosen mucus.
  • Avoid citrus fruits as they may worsen the cough. Eat fruits rich in water content, such as pears, watermelon, peaches and pineapples.
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How Soon It Starts Working

The time required for Kolder DMR 100ml Syp to start to work: Kolder DMR 100ml Syp starts to show its action within 15 to 30 minutes of administration. 

The time for which the effects of Kolder DMR 100ml Syp last: Kolder DMR 100ml Syp effect lasts for 4 to 6 hours.

What if you forget to take Kolder DMR 100ml Syp

If you miss a dose of Kolder DMR 100ml Syp, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed dose.

Storage

• Store in a cool and dry place away from sunlight.• Keep Kolder DMR 100ml Syp out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • If you are allergic to Kolder DMR 100ml Syp or any other medicines, please tell your doctor.
  • If you are pregnant or breastfeeding, it is advised to inform your doctor before using it.
  • Kolder DMR 100ml Syp is not recommended for children below 12 years of age.
  • If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking this medicine.
  • Avoid taking Kolder DMR 100ml Syp if you have taken medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine and methylene blue injection in the past 14 days.
  • If you have glaucoma, urinary problems, enlarged prostate, phenylketonuria (a birth defect that causes accumulation of amino acid, phenylalanine in the body), cough with mucus or cough caused by asthma, smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), inform your doctor before taking Kolder DMR 100ml Syp.

Drug-Drug Interactions

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Drug-Drug Interaction: Kolder DMR 100ml Syp may have interaction with anti-allergic drugs (diphenhydramine), anti-psychotic (escitalopram, desvenlafaxine, vilazodone), pain killer (aspirin), cold medicines (acetaminophen), antibiotics (amoxicillin), anti-depressants (linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine), beta-blockers (metoprolol, atenolol), muscle relaxants (carisoprodol, cyclobenzaprine).

Drug-Food Interaction: Kolder DMR 100ml Syp may interact with alcohol. Therefore, avoid alcohol consumption with Kolder DMR 100ml Syp as it may increase the risk of adverse effects such as drowsiness, dizziness or difficulty in concentrating.

Drug-Disease Interaction: Kolder DMR 100ml Syp is known to interact in patients with liver or kidney disease, asthma, diabetes, glaucoma, cardiovascular diseases, enlarged prostate gland, chronic bronchitis or emphysema (a lung condition causing shortness of breath).

Chlorpheniramine + Phenylephrine + DextromethorphanPropofol
Critical
Chlorpheniramine + Phenylephrine + DextromethorphanTranylcypromine
Critical

Drug-Drug Interactions

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Chlorpheniramine + Phenylephrine + DextromethorphanPropofol
Critical
How does the drug interact with Kolder DMR 100ml Syp:
Taking Kolder DMR 100ml Syp with Propofol may lead to increased levels of phenylephrine leading to side effects.

How to manage the interaction:
Taking Kolder DMR 100ml Syp with Propofol is not recommended, as it can lead to an interaction, but it can be taken if prescribed by a doctor. Do not discontinue the medications without consulting a doctor.
Chlorpheniramine + Phenylephrine + DextromethorphanTranylcypromine
Critical
How does the drug interact with Kolder DMR 100ml Syp:
Co-administration of Kolder DMR 100ml Syp with Tranylcypromine can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Although taking Kolder DMR 100ml Syp together with Tranylcypromine is not recommended as it can result in an interaction, it can be taken if prescribed by a doctor. However, if you develop confusion, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Chlorpheniramine + Phenylephrine + DextromethorphanPotassium chloride
Critical
How does the drug interact with Kolder DMR 100ml Syp:
Taking Kolder DMR 100ml Syp with Potassium chloride may make potassium more irritating to your upper intestine and stomach.

How to manage the interaction:
Taking Kolder DMR 100ml Syp with Potassium chloride it not recommended as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience any symptoms such as severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult a doctor. Do not discontinue any medications without a doctor's advice.
Chlorpheniramine + Phenylephrine + DextromethorphanSelegiline
Critical
How does the drug interact with Kolder DMR 100ml Syp:
Co-administration of Kolder DMR 100ml Syp with selegiline can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body) and high blood pressure.

How to manage the interaction:
Co-administration of Kolder DMR 100ml Syp with Selegiline can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you notice any of these symptoms - confusion, seizure, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, diarrhea, severe headache, chest pain, sudden numbness or weakness (especially on one side of the body), speech difficulties, lightheadedness, and/or fainting - make sure to contact a doctor right away. Do not stop using any medications without consulting a doctor.
Chlorpheniramine + Phenylephrine + DextromethorphanPhenelzine
Critical
How does the drug interact with Kolder DMR 100ml Syp:
Co-administration of Kolder DMR 100ml Syp with Phenelzine can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body) and high blood pressure.

How to manage the interaction:
Co-administration of Kolder DMR 100ml Syp with Phenelzine can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you notice any of these symptoms - confusion, seizure, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, diarrhea, severe headache, chest pain, sudden numbness or weakness (especially on one side of the body), speech difficulties, lightheadedness, and/or fainting - make sure to contact a doctor right away. Do not stop using any medications without consulting a doctor.
Chlorpheniramine + Phenylephrine + DextromethorphanPotassium citrate
Critical
How does the drug interact with Kolder DMR 100ml Syp:
Taking Kolder DMR 100ml Syp with Potassium chloride may make potassium more irritating to your upper intestine and stomach.

How to manage the interaction:
Taking Kolder DMR 100ml Syp with Potassium citrate is not recommended as it can lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience any symptoms such as severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Chlorpheniramine + Phenylephrine + DextromethorphanProcarbazine
Critical
How does the drug interact with Kolder DMR 100ml Syp:
Co-administration of Kolder DMR 100ml Syp with Procarbazine can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body) and high blood pressure.

How to manage the interaction:
Co-administration of Kolder DMR 100ml Syp with Procarbazine can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you notice any of these symptoms - confusion, seizure, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, diarrhea, severe headache, chest pain, sudden numbness or weakness (especially on one side of the body), speech difficulties, lightheadedness, and/or fainting - make sure to contact a doctor right away. Do not stop using any medications without consulting a doctor.
Chlorpheniramine + Phenylephrine + DextromethorphanRasagiline
Critical
How does the drug interact with Kolder DMR 100ml Syp:
Taking Kolder DMR 100ml Syp with Dextromethorphan can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Kolder DMR 100ml Syp with Rasagiline is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like confusion, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking, incoordination, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor. Do not discontinue any medications without consulting a doctor.
Chlorpheniramine + Phenylephrine + DextromethorphanIsocarboxazid
Critical
How does the drug interact with Kolder DMR 100ml Syp:
Co-administration of Kolder DMR 100ml Syp with Isocarboxazid can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Although taking Kolder DMR 100ml Syp together with Isocarboxazid is not recommended as it can result in an interaction, it can be taken if prescribed by a doctor. However, if you develop confusion, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Chlorpheniramine + Phenylephrine + DextromethorphanMethylene blue
Critical
How does the drug interact with Kolder DMR 100ml Syp:
Co-administration of Kolder DMR 100ml Syp with Methylene blue can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Although taking Kolder DMR 100ml Syp together with Methylene blue is not recommended as it can result in an interaction, it can be taken if prescribed by a doctor. However, if you develop confusion, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[COUGH AND COLD PREPARATIONS ]

FAQs

Kolder DMR 100ml Syp belongs to a class of medication called 'cough and cold preparations primarily used to treat dry cough. Coughing (dry or productive) is the body way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection.
Kolder DMR 100ml Syp contains Chlorpheniramine maleate, Phenylephrine, and Dextromethorphan. Chlorpheniramine works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine is a decongestant that helps in shrinking the blood vessels located in the nasal passage, thereby reducing stuffy nose. Dextromethorphan works by blocking the transmission of nerve signals from the cough center in the brain to the muscles that produce cough.
No, you should not take Kolder DMR 100ml Syp if you need to undergo surgery as it may lead to excessive drowsiness and sleepiness when given along with anaesthesia. Therefore, if you are about to undergo any surgery, please inform your doctor that you are taking Kolder DMR 100ml Syp. Your doctor may advise you to stop taking Kolder DMR 100ml Syp 72 hours before the surgery.
It is not recommended to take Kolder DMR 100ml Syp along with any anti-depressant medication, especially MAO inhibitors (linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine), as it may lead to unpleasant side-effects or any drug interaction. Also, Kolder DMR 100ml Syp should be taken at least 15 days after your last dose of anti-depressants.
Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take Kolder DMR 100ml Syp and skip the missed dose. Do not take extra medicine to make up for the missed dose.
Kolder DMR 100ml Syp should be used with caution and only when prescribed by a doctor in patients with glaucoma, as Kolder DMR 100ml Syp may rarely worsen the symptoms of glaucoma.

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Country of origin

India

Manufacturer/Marketer address

913, D-Mall, Netaji Subhash Place Pitampura New Deli New Delhi DL 110034 IN
Other Info - KOL0108
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